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The map label for this gene is fabF [H]

Identifier: 71906811

GI number: 71906811

Start: 1277502

End: 1278716

Strand: Reverse

Name: fabF [H]

Synonym: Daro_1172

Alternate gene names: 71906811

Gene position: 1278716-1277502 (Counterclockwise)

Preceding gene: 71906812

Following gene: 71906810

Centisome position: 28.41

GC content: 62.96

Gene sequence:

>1215_bases
ATGAAACGACGCGTCGTCATCACGGGTCTCGGACTTGTTTCGCCTCTCGGCGACACACCGGATCAAGTGTTCGAGAGCGT
GATGTCTGGCCGCTCGGCCGTTGAACTCTGGTCTGACGACGAAATCGATCCCCCGGCCGTCGTGGCGAGAAGCCCCTTCG
ATGTTAGCCGCTGGTTCAATCGTCTTCAGCTTGCCGGCGTTGATCGGGTTAGCCAGCTGGCTGTCGCCGCAGCCGAAATG
GCCAGAGCGGATGCCGGTCTCGCGGCGCTCGACGAGAACAGTGGCGTCTATGTCGGAAGCGGCATGGGCGGTGCAGCGGC
AATAGAAAAGGCTTTCAACAACCATCTCGAATCCGGACGCGTCCCGCCGCTGACCGTACCGGCCTTCATGCCCAATGCAC
CGGCCGCCCATGTGGCAATGCGGGCAGGCATCCACGGACCGGTATTTACCTATTCGATCGCCTGCGCCTCGTCAGCTGTG
GCCATTTCCGAAGCCGCCAAGGCAGTTTCCCGGGGCGAGATCGATTATGCGTTGGCCGGTGGCAGCGAAGCCCTGCTCGT
GCCCAGTGTCATTCGTGCCTGGCAAGCCCTGCAAACGCTGGCCTCTCCCACTGGCGACGATCCCTCGAAAGCCTGTCAGC
CGTTTAGCAAAGACCGCTCCGGTCTGGTCCTTGGCGAAGGCTCCGCCTTTCTGGTCATTGAATCGCTGGACTCCGCCCTG
GCACGGGGAGCGAGAATCTACGCCGAACTGGCTGGCAGCGGCATCTCTTGTGATGCAACCCACCTGACCAAGCCCGATGC
GGCCGGACAGGTTCGGGCGCTCCATGCCGCCTTGCGCGACAGCGGCCTTTCTCCGACCGAGATCGGCTACTGCAATGCCC
ACGGTACGGCCACCCTGGTCGGCGATGTCATCGAGTGCGAGGCGCTTCGGCAAGTCTGGGGGAACGATATCGACCAACTG
GCCGTCAGCTCGACCAAATCGATGCACGGCCATCTGCTCGGCGCCGCCGGTGCACTCGAAGCCGTCATTACGACCCTGGC
GGTTGCGCGGGGCGCCTTGCCACCGAACATGAACATGACGGAACAGGACCCGGCTTGCGGCATTCGCGTCGTTACCGAAC
CCGGCACGCCAGCCCCCGACCTGAAAGCGGCCATCAGCAACTCGTTCGCCTTCGGCGGAACGAACGCCGTTCTGGTATTC
CGCCGAATAGATTGA

Upstream 100 bases:

>100_bases
AGGAACATTTCAACCTGGACTTTCCGGATGACCGGGCTGACGTCAAGACGCTCGCAGGTCTTGCAGCGTTGATTGACGAA
CTCAAGCTGGCCGCCATCGC

Downstream 100 bases:

>100_bases
AACACGACGACCGAGCCCTGATGATGAAAAGGCTACTTGCTGTTTTTGTCTTGGCGCTAGCGCTGGCACCCCTCGCCGTT
GCCGAGGCCCAGCCGGATGC

Product: Beta-ketoacyl synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MKRRVVITGLGLVSPLGDTPDQVFESVMSGRSAVELWSDDEIDPPAVVARSPFDVSRWFNRLQLAGVDRVSQLAVAAAEM
ARADAGLAALDENSGVYVGSGMGGAAAIEKAFNNHLESGRVPPLTVPAFMPNAPAAHVAMRAGIHGPVFTYSIACASSAV
AISEAAKAVSRGEIDYALAGGSEALLVPSVIRAWQALQTLASPTGDDPSKACQPFSKDRSGLVLGEGSAFLVIESLDSAL
ARGARIYAELAGSGISCDATHLTKPDAAGQVRALHAALRDSGLSPTEIGYCNAHGTATLVGDVIECEALRQVWGNDIDQL
AVSSTKSMHGHLLGAAGALEAVITTLAVARGALPPNMNMTEQDPACGIRVVTEPGTPAPDLKAAISNSFAFGGTNAVLVF
RRID

Sequences:

>Translated_404_residues
MKRRVVITGLGLVSPLGDTPDQVFESVMSGRSAVELWSDDEIDPPAVVARSPFDVSRWFNRLQLAGVDRVSQLAVAAAEM
ARADAGLAALDENSGVYVGSGMGGAAAIEKAFNNHLESGRVPPLTVPAFMPNAPAAHVAMRAGIHGPVFTYSIACASSAV
AISEAAKAVSRGEIDYALAGGSEALLVPSVIRAWQALQTLASPTGDDPSKACQPFSKDRSGLVLGEGSAFLVIESLDSAL
ARGARIYAELAGSGISCDATHLTKPDAAGQVRALHAALRDSGLSPTEIGYCNAHGTATLVGDVIECEALRQVWGNDIDQL
AVSSTKSMHGHLLGAAGALEAVITTLAVARGALPPNMNMTEQDPACGIRVVTEPGTPAPDLKAAISNSFAFGGTNAVLVF
RRID
>Mature_404_residues
MKRRVVITGLGLVSPLGDTPDQVFESVMSGRSAVELWSDDEIDPPAVVARSPFDVSRWFNRLQLAGVDRVSQLAVAAAEM
ARADAGLAALDENSGVYVGSGMGGAAAIEKAFNNHLESGRVPPLTVPAFMPNAPAAHVAMRAGIHGPVFTYSIACASSAV
AISEAAKAVSRGEIDYALAGGSEALLVPSVIRAWQALQTLASPTGDDPSKACQPFSKDRSGLVLGEGSAFLVIESLDSAL
ARGARIYAELAGSGISCDATHLTKPDAAGQVRALHAALRDSGLSPTEIGYCNAHGTATLVGDVIECEALRQVWGNDIDQL
AVSSTKSMHGHLLGAAGALEAVITTLAVARGALPPNMNMTEQDPACGIRVVTEPGTPAPDLKAAISNSFAFGGTNAVLVF
RRID

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=417, Percent_Identity=36.6906474820144, Blast_Score=244, Evalue=8e-65,
Organism=Homo sapiens, GI223972627, Length=145, Percent_Identity=45.5172413793103, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI41872631, Length=268, Percent_Identity=27.9850746268657, Blast_Score=89, Evalue=1e-17,
Organism=Escherichia coli, GI1787337, Length=414, Percent_Identity=36.231884057971, Blast_Score=251, Evalue=8e-68,
Organism=Escherichia coli, GI1788663, Length=411, Percent_Identity=36.0097323600973, Blast_Score=213, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI71983541, Length=409, Percent_Identity=36.4303178484108, Blast_Score=217, Evalue=8e-57,
Organism=Caenorhabditis elegans, GI71983535, Length=266, Percent_Identity=38.7218045112782, Blast_Score=171, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI212642053, Length=346, Percent_Identity=27.4566473988439, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17550940, Length=258, Percent_Identity=28.2945736434109, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320904, Length=444, Percent_Identity=31.3063063063063, Blast_Score=191, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24644341, Length=415, Percent_Identity=39.2771084337349, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI221330659, Length=276, Percent_Identity=26.0869565217391, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19920632, Length=276, Percent_Identity=26.0869565217391, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24581345, Length=278, Percent_Identity=28.0575539568345, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 41647; Mature: 41647

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRRVVITGLGLVSPLGDTPDQVFESVMSGRSAVELWSDDEIDPPAVVARSPFDVSRWFN
CCCEEEEEECCHHCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCEEECCCCCHHHHHH
RLQLAGVDRVSQLAVAAAEMARADAGLAALDENSGVYVGSGMGGAAAIEKAFNNHLESGR
HHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCHHHHHHHHHHHHHHCCC
VPPLTVPAFMPNAPAAHVAMRAGIHGPVFTYSIACASSAVAISEAAKAVSRGEIDYALAG
CCCEECCCCCCCCCHHHHHHHCCCCCCHHEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEC
GSEALLVPSVIRAWQALQTLASPTGDDPSKACQPFSKDRSGLVLGEGSAFLVIESLDSAL
CCCEEHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCEEEECCCEEEEEEHHHHHH
ARGARIYAELAGSGISCDATHLTKPDAAGQVRALHAALRDSGLSPTEIGYCNAHGTATLV
HHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHH
GDVIECEALRQVWGNDIDQLAVSSTKSMHGHLLGAAGALEAVITTLAVARGALPPNMNMT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EQDPACGIRVVTEPGTPAPDLKAAISNSFAFGGTNAVLVFRRID
CCCCCCCEEEEECCCCCCCHHHHHHHCCCEECCCCEEEEEEECC
>Mature Secondary Structure
MKRRVVITGLGLVSPLGDTPDQVFESVMSGRSAVELWSDDEIDPPAVVARSPFDVSRWFN
CCCEEEEEECCHHCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCEEECCCCCHHHHHH
RLQLAGVDRVSQLAVAAAEMARADAGLAALDENSGVYVGSGMGGAAAIEKAFNNHLESGR
HHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCHHHHHHHHHHHHHHCCC
VPPLTVPAFMPNAPAAHVAMRAGIHGPVFTYSIACASSAVAISEAAKAVSRGEIDYALAG
CCCEECCCCCCCCCHHHHHHHCCCCCCHHEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEC
GSEALLVPSVIRAWQALQTLASPTGDDPSKACQPFSKDRSGLVLGEGSAFLVIESLDSAL
CCCEEHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCEEEECCCEEEEEEHHHHHH
ARGARIYAELAGSGISCDATHLTKPDAAGQVRALHAALRDSGLSPTEIGYCNAHGTATLV
HHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHH
GDVIECEALRQVWGNDIDQLAVSSTKSMHGHLLGAAGALEAVITTLAVARGALPPNMNMT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EQDPACGIRVVTEPGTPAPDLKAAISNSFAFGGTNAVLVFRRID
CCCCCCCEEEEECCCCCCCHHHHHHHCCCEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]