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The map label for this gene is ywfA [H]

Identifier: 71906735

GI number: 71906735

Start: 1198750

End: 1199949

Strand: Reverse

Name: ywfA [H]

Synonym: Daro_1096

Alternate gene names: 71906735

Gene position: 1199949-1198750 (Counterclockwise)

Preceding gene: 71906736

Following gene: 71906732

Centisome position: 26.66

GC content: 68.58

Gene sequence:

>1200_bases
ATGCCCGAAGCTCCGGAAGCCCAACACCGCCGCGCTGTCATGCTGCTCTCCGTCGCCGCCTTCGCCAGCGCGGCGGCAGC
GCGGCTGTGCGACCCGATGCTGCCCGACCTCGCTCGCAGCTTCACGGCCAGCCCGACTGCCGTCGCCTCGGTCATCTCCT
CGTTCGCCATCGCCTATGGCCTGACCCAGGCCATGTTCGGCCCGCTCGGCGACCGCCTCGGCAAATACCGCCTGATCGCC
CTGACCACCCTGCTCAGCACGCTGGGCGCACTCGGCTCGGCCATCGCCTGGTCGCTCGATGCGCTGGTCGTCTCCCGCGT
GCTGCTCGGCGCCACGGCGGCCGGCATCATCCCGCTCTCCATGGCGTGGATCGGCGACACGGTGCCCTACGAACAACGGC
AAGCCACGCTCGCCCGCTTCCTGGGCGGGCAGATTCTCGGCGCCATCGGCGGCCAGTTCATTGGTGGCGTGTTCACCGAC
ACGCTCGGCTGGCGCTGGGCCTTCGCCTTCCTGGCCGGGCTCTACCTGATCATCGGCGCCGTCGTCCTGCTCGAATCGCG
GGCCAACCCGAGCACCCATCACCGCCATGCCGATACCCCCCGCCAGGGCATTCTCGGCCAGGCCGCGCAGGTCTTCGCCC
AACCGTGGGCCCGGGTCATCCTGAGCATTGTTTTCCTCGAAGGCATGCTGGTGTTCGGTGCCCTGGCCTTCGTGCCCTCC
TACCTGCACGAACATTTCGGCCTCAGCCTCACCATGGCCGGCGCCGCCATGGCCTTCTTCGGCCTCGGCGGCCTGTCGTA
CATCCTTGCCGCCCGGCATTTTGTCCGCCTCCTCGGCGAAGTCGGGCTGGCCACCGGCGGCGGCATTCTCATCGCGCTCG
GCTGGGCGATGCTGGCCTGGGGCACCACCTGGCTATGGGCCCTGCCGGCCAGCTATTTTGTCGGCCTCGGCTTCTACATG
CTGCACAACACCCTGCAGACCAACGCCACCCAGATGGCCCCCGCCGTACGCGGCACCGCGGTCTCCTTGTTCGCCTCCAG
TTTCTTCCTCGGCCAATCGCTCGGCGTCACCCTCGCTGCCCACATCCTGGCCGCATCCGGCATCCTCCCCATGCTGCTGA
TCGCTGCCATCGGCACACCGCTGGTTGGTGGTACGCTGGCCTGGCTTCTCTCCCGGCACCACCGCATACATTCCGCCTAG

Upstream 100 bases:

>100_bases
AATGATGTTCGTCAGCGATGTCTTCGATCCCGAATTGCGCCTGCGCTCGTTGGACATCGCCACCCGCGCCTGCTGGCAGC
CCTGAGCCCGACCTGACGCC

Downstream 100 bases:

>100_bases
CTTATCGACGGATTGACACTACACCGGTATTGGCCAGGCAGCGTGATCCCGGCCCGCCTAAGCTCAGCGCCGCCGGCCGC
ACGGCTCCGTCAGCAATGGG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MPEAPEAQHRRAVMLLSVAAFASAAAARLCDPMLPDLARSFTASPTAVASVISSFAIAYGLTQAMFGPLGDRLGKYRLIA
LTTLLSTLGALGSAIAWSLDALVVSRVLLGATAAGIIPLSMAWIGDTVPYEQRQATLARFLGGQILGAIGGQFIGGVFTD
TLGWRWAFAFLAGLYLIIGAVVLLESRANPSTHHRHADTPRQGILGQAAQVFAQPWARVILSIVFLEGMLVFGALAFVPS
YLHEHFGLSLTMAGAAMAFFGLGGLSYILAARHFVRLLGEVGLATGGGILIALGWAMLAWGTTWLWALPASYFVGLGFYM
LHNTLQTNATQMAPAVRGTAVSLFASSFFLGQSLGVTLAAHILAASGILPMLLIAAIGTPLVGGTLAWLLSRHHRIHSA

Sequences:

>Translated_399_residues
MPEAPEAQHRRAVMLLSVAAFASAAAARLCDPMLPDLARSFTASPTAVASVISSFAIAYGLTQAMFGPLGDRLGKYRLIA
LTTLLSTLGALGSAIAWSLDALVVSRVLLGATAAGIIPLSMAWIGDTVPYEQRQATLARFLGGQILGAIGGQFIGGVFTD
TLGWRWAFAFLAGLYLIIGAVVLLESRANPSTHHRHADTPRQGILGQAAQVFAQPWARVILSIVFLEGMLVFGALAFVPS
YLHEHFGLSLTMAGAAMAFFGLGGLSYILAARHFVRLLGEVGLATGGGILIALGWAMLAWGTTWLWALPASYFVGLGFYM
LHNTLQTNATQMAPAVRGTAVSLFASSFFLGQSLGVTLAAHILAASGILPMLLIAAIGTPLVGGTLAWLLSRHHRIHSA
>Mature_398_residues
PEAPEAQHRRAVMLLSVAAFASAAAARLCDPMLPDLARSFTASPTAVASVISSFAIAYGLTQAMFGPLGDRLGKYRLIAL
TTLLSTLGALGSAIAWSLDALVVSRVLLGATAAGIIPLSMAWIGDTVPYEQRQATLARFLGGQILGAIGGQFIGGVFTDT
LGWRWAFAFLAGLYLIIGAVVLLESRANPSTHHRHADTPRQGILGQAAQVFAQPWARVILSIVFLEGMLVFGALAFVPSY
LHEHFGLSLTMAGAAMAFFGLGGLSYILAARHFVRLLGEVGLATGGGILIALGWAMLAWGTTWLWALPASYFVGLGFYML
HNTLQTNATQMAPAVRGTAVSLFASSFFLGQSLGVTLAAHILAASGILPMLLIAAIGTPLVGGTLAWLLSRHHRIHSA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787880, Length=409, Percent_Identity=25.6723716381418, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790195, Length=189, Percent_Identity=32.8042328042328, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789042, Length=153, Percent_Identity=27.4509803921569, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788710, Length=182, Percent_Identity=27.4725274725275, Blast_Score=62, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24583789, Length=227, Percent_Identity=24.6696035242291, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41905; Mature: 41774

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PEAPEAQHRRAVMLLSVAAFASAAAARLCDPMLPDLARSFTASPTAVASVISSFAIAYG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LTQAMFGPLGDRLGKYRLIALTTLLSTLGALGSAIAWSLDALVVSRVLLGATAAGIIPLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAWIGDTVPYEQRQATLARFLGGQILGAIGGQFIGGVFTDTLGWRWAFAFLAGLYLIIGA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVLLESRANPSTHHRHADTPRQGILGQAAQVFAQPWARVILSIVFLEGMLVFGALAFVPS
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLHEHFGLSLTMAGAAMAFFGLGGLSYILAARHFVRLLGEVGLATGGGILIALGWAMLAW
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
GTTWLWALPASYFVGLGFYMLHNTLQTNATQMAPAVRGTAVSLFASSFFLGQSLGVTLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HILAASGILPMLLIAAIGTPLVGGTLAWLLSRHHRIHSA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]