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The map label for this gene is mcp4 [H]

Identifier: 71906201

GI number: 71906201

Start: 623889

End: 625406

Strand: Reverse

Name: mcp4 [H]

Synonym: Daro_0561

Alternate gene names: 71906201

Gene position: 625406-623889 (Counterclockwise)

Preceding gene: 71906202

Following gene: 71906198

Centisome position: 13.89

GC content: 58.23

Gene sequence:

>1518_bases
ATGGGATTATTCGGTAACAACGCAGCGCTCGAAAAAATTGACCGCGATATTGCGGCAATCGCCGAGGGTTCCGCAGATTT
GTCACATTCGGTCGGCACAACCGGAAATGATGCGGCGGGAAGGATTTCCGGAAATATCAACCGTTTCTTTGGGCGTGTTC
GCAGCCTGATTTCGCATTCCCGCGAACGAAGCGTCAGCATCGCTGCCGATGCGGCCCGGATGAACCAACTGGTCCAGCAG
ACGGACGATGCGGTACGCCGGCAGGAAGCCTTGGCCGCCACGGTTTTCGACTCAAGCAACCGCGTCAATCAGGCGGTTGG
TGAAGTCGCCATGAACTCCGACGCCATCCAGTCGTCGACCCAGAACAACCTCGACCTCGCCCAACGTTCGCTTGAGCAGA
TGGAAACCGTCGCCTCGACGATGCGTTCGACCAATGCCCACATCGAACATTTCTCGTCGACGGTGAGCGAACTGCACACC
AGCTCGATGAAAATCAACGAGATCGTCTCGCTGATCAACGACATTTCCGATCAGACCAACCTGCTGGCACTGAATGCCGC
CATCGAAGCTGCTCGCGCTGGTGAGGCCGGACGTGGTTTCGCCGTCGTCGCCGACGAAGTGCGCAAGCTGGCCGAAAAGG
TCAAGACCGCCACCCAGGTGATCGGCCAGAACACCCAGTCGATGATCAATCTGGTTTCCGACACCTCGGCCAAGACGCAA
ACCATTGTCGGCGAGGTGACCAGGGCCAACGGCTATATCGAAACCTCGGCCGCCGACCTGACGACCATGGTCGGCGATTT
CAAGCAGACGACCGAGCAGCTTGCCACTATTTCCAGTGCCATCTACAACCTGCGCGAAAGCAACCAGGCCATCCATAGCG
AAGTCGAAGAAATTCGCGATCACTCACGCGAGATTTCCGGCCGCATGCGGCAGTGCATCGACTCGGCCAAGACCTTGCGC
GAATCGACCGAAGACCTGCAATGCACGCTGGCCGATTTCCGCACTGGCAACAACATGTTCGACACCCTGCACGACAAGTG
CACTGCATTCCGCGATGACGTCGCCGGAATCCTCCAAAAGCTGGCCGACCGCGGCGTGAACATTTTCGACCAGGCCTACA
AGGAAATCCCCGGTTCGAACCCGAAACGCTACACCACTGCCTACGATAACCAGTGCGACGGCGAACTCACCCGCCTTTAC
GATAATCTGCTGCGCGAGGTGCCTGGCCTGGTCTACTCGCTCTCCATGGATACCAACGGCTATGCCCCGGCCCATAACGC
AGTGTTTTCCAACCCGCCGAGTGGCGATCCGGCCATCGACCTGGTGAAATGCCGGCACAAGCGCATTTTCAATGACCCTG
TCGGCATGAAAGGTGCGAAGAACCAGAAACCTTCGCTGTTCCAGACCTATGTTCGCGACACGGGGGAAATCCTCGCCGAC
CTGACGATGCCGGTCATGGTCAACGGCCGCCACTGGGGCGGGGTGCGGATCGGCTTCAAAACCGATCTGGTCAAGTAA

Upstream 100 bases:

>100_bases
AAGCCTCGTCCTTAGTGACAAGCATCTGAGCGCAGGCGTATGATCTGGCCACCTTTTGCCCTATCCCGGCAGGCCATAAA
AACAGATCAGGAGACGATCC

Downstream 100 bases:

>100_bases
TCCGAGTCCGGCAGCCAGCTGCCGGGCAATAAAAAGGCGCCGCAAGGCGCCTTTTTATTGCCCGGAGATCCATTCCCGCC
CAGGTCACACTGATCCACCG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MGLFGNNAALEKIDRDIAAIAEGSADLSHSVGTTGNDAAGRISGNINRFFGRVRSLISHSRERSVSIAADAARMNQLVQQ
TDDAVRRQEALAATVFDSSNRVNQAVGEVAMNSDAIQSSTQNNLDLAQRSLEQMETVASTMRSTNAHIEHFSSTVSELHT
SSMKINEIVSLINDISDQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAEKVKTATQVIGQNTQSMINLVSDTSAKTQ
TIVGEVTRANGYIETSAADLTTMVGDFKQTTEQLATISSAIYNLRESNQAIHSEVEEIRDHSREISGRMRQCIDSAKTLR
ESTEDLQCTLADFRTGNNMFDTLHDKCTAFRDDVAGILQKLADRGVNIFDQAYKEIPGSNPKRYTTAYDNQCDGELTRLY
DNLLREVPGLVYSLSMDTNGYAPAHNAVFSNPPSGDPAIDLVKCRHKRIFNDPVGMKGAKNQKPSLFQTYVRDTGEILAD
LTMPVMVNGRHWGGVRIGFKTDLVK

Sequences:

>Translated_505_residues
MGLFGNNAALEKIDRDIAAIAEGSADLSHSVGTTGNDAAGRISGNINRFFGRVRSLISHSRERSVSIAADAARMNQLVQQ
TDDAVRRQEALAATVFDSSNRVNQAVGEVAMNSDAIQSSTQNNLDLAQRSLEQMETVASTMRSTNAHIEHFSSTVSELHT
SSMKINEIVSLINDISDQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAEKVKTATQVIGQNTQSMINLVSDTSAKTQ
TIVGEVTRANGYIETSAADLTTMVGDFKQTTEQLATISSAIYNLRESNQAIHSEVEEIRDHSREISGRMRQCIDSAKTLR
ESTEDLQCTLADFRTGNNMFDTLHDKCTAFRDDVAGILQKLADRGVNIFDQAYKEIPGSNPKRYTTAYDNQCDGELTRLY
DNLLREVPGLVYSLSMDTNGYAPAHNAVFSNPPSGDPAIDLVKCRHKRIFNDPVGMKGAKNQKPSLFQTYVRDTGEILAD
LTMPVMVNGRHWGGVRIGFKTDLVK
>Mature_504_residues
GLFGNNAALEKIDRDIAAIAEGSADLSHSVGTTGNDAAGRISGNINRFFGRVRSLISHSRERSVSIAADAARMNQLVQQT
DDAVRRQEALAATVFDSSNRVNQAVGEVAMNSDAIQSSTQNNLDLAQRSLEQMETVASTMRSTNAHIEHFSSTVSELHTS
SMKINEIVSLINDISDQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAEKVKTATQVIGQNTQSMINLVSDTSAKTQT
IVGEVTRANGYIETSAADLTTMVGDFKQTTEQLATISSAIYNLRESNQAIHSEVEEIRDHSREISGRMRQCIDSAKTLRE
STEDLQCTLADFRTGNNMFDTLHDKCTAFRDDVAGILQKLADRGVNIFDQAYKEIPGSNPKRYTTAYDNQCDGELTRLYD
NLLREVPGLVYSLSMDTNGYAPAHNAVFSNPPSGDPAIDLVKCRHKRIFNDPVGMKGAKNQKPSLFQTYVRDTGEILADL
TMPVMVNGRHWGGVRIGFKTDLVK

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=218, Percent_Identity=34.4036697247706, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI2367378, Length=276, Percent_Identity=28.9855072463768, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787690, Length=178, Percent_Identity=38.2022471910112, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788195, Length=274, Percent_Identity=29.5620437956204, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789453, Length=176, Percent_Identity=33.5227272727273, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 55102; Mature: 54971

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00639 THIOL_PROTEASE_HIS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLFGNNAALEKIDRDIAAIAEGSADLSHSVGTTGNDAAGRISGNINRFFGRVRSLISHS
CCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RERSVSIAADAARMNQLVQQTDDAVRRQEALAATVFDSSNRVNQAVGEVAMNSDAIQSST
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCC
QNNLDLAQRSLEQMETVASTMRSTNAHIEHFSSTVSELHTSSMKINEIVSLINDISDQTN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
LLALNAAIEAARAGEAGRGFAVVADEVRKLAEKVKTATQVIGQNTQSMINLVSDTSAKTQ
EEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHH
TIVGEVTRANGYIETSAADLTTMVGDFKQTTEQLATISSAIYNLRESNQAIHSEVEEIRD
HHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HSREISGRMRQCIDSAKTLRESTEDLQCTLADFRTGNNMFDTLHDKCTAFRDDVAGILQK
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LADRGVNIFDQAYKEIPGSNPKRYTTAYDNQCDGELTRLYDNLLREVPGLVYSLSMDTNG
HHHCCCCHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCC
YAPAHNAVFSNPPSGDPAIDLVKCRHKRIFNDPVGMKGAKNQKPSLFQTYVRDTGEILAD
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LTMPVMVNGRHWGGVRIGFKTDLVK
HCCCEEECCCCCCCEEECCHHCCCC
>Mature Secondary Structure 
GLFGNNAALEKIDRDIAAIAEGSADLSHSVGTTGNDAAGRISGNINRFFGRVRSLISHS
CCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RERSVSIAADAARMNQLVQQTDDAVRRQEALAATVFDSSNRVNQAVGEVAMNSDAIQSST
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCC
QNNLDLAQRSLEQMETVASTMRSTNAHIEHFSSTVSELHTSSMKINEIVSLINDISDQTN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
LLALNAAIEAARAGEAGRGFAVVADEVRKLAEKVKTATQVIGQNTQSMINLVSDTSAKTQ
EEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHH
TIVGEVTRANGYIETSAADLTTMVGDFKQTTEQLATISSAIYNLRESNQAIHSEVEEIRD
HHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HSREISGRMRQCIDSAKTLRESTEDLQCTLADFRTGNNMFDTLHDKCTAFRDDVAGILQK
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LADRGVNIFDQAYKEIPGSNPKRYTTAYDNQCDGELTRLYDNLLREVPGLVYSLSMDTNG
HHHCCCCHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCC
YAPAHNAVFSNPPSGDPAIDLVKCRHKRIFNDPVGMKGAKNQKPSLFQTYVRDTGEILAD
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LTMPVMVNGRHWGGVRIGFKTDLVK
HCCCEEECCCCCCCEEECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]