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The map label for this gene is dctB [H]

Identifier: 71906118

GI number: 71906118

Start: 538845

End: 540695

Strand: Reverse

Name: dctB [H]

Synonym: Daro_0478

Alternate gene names: 71906118

Gene position: 540695-538845 (Counterclockwise)

Preceding gene: 71906119

Following gene: 71906117

Centisome position: 12.01

GC content: 68.4

Gene sequence:

>1851_bases
ATGCCCCGACTCCGCTCCCTGCCGCTGTTGCTGCTCTGCCTGCTGCTGGTCGCCCTGAGCGGCTTCTCGGCCTACCGCAT
CGCCCAGCGCCTGGGCATCGCCGACCTGCAGGCGACCGGCCTGCACCGGCTCGATCTCTATGCCGCCAGCTTGGAACGCG
AGATCAGCAAGTACGCCTTCCTGCCCGGCACGCTGAGCCTGGAGCCGGAAGTTCTCGACCTGCTTGCCGGGACAGCCGGC
GACAGCGCCGCCGCCCGTGTCAACGGCTATCTCGAAAAGCTCAACGAACGTGCCGGCACGCTGTCGATTTACGTCATGGA
CACCCGCGGCAAGGTGCTCGCCACCAGCAACTGGCGGCGTCCAGACAGTTTTCTCGGCGAAGAGCTGTCCTTCCGCCCCT
ATTTCCGCGAGGCGCTGGAGAGCGGCAACGGCCGTTTCTTCGGCATCGGCACCACGCGCGGCGAGCCCGGCTATTACCTC
GCCTCGGCACTGACCGGCGACAACGGCACGCTGGGCGTCGCGGTGATCAAGGTCAGCCTCGAACAGTTGGAAAAATCGTG
GACCACGGTCGAGGCGCCGGTGCTGGTCGCTGACGAAAATGGCGTGGTCATCCTGTCCGCCGTGCCCGGCTGGAAATTCA
CCACCCTGCGCCCGCTCGACGACAGCACGCGCGCCGCCTTCGACCACACCCAGCAATACAACCGGCGCGCCCTGCAACCC
CTGGGCATCAAGCAGATCGAGGACTACGACCACGGCGCCCGCCTGGTGCGCATTGCCGCCAACGGCCCGGAAACGGTGTC
GGTCTACCCGGTCACCGGACGCTTCCTCGAACAGTCGCGCACCCTGCCCGGCACACCGTGGACGCTGACCGTGCTGTCCC
ATCTCGAACAGGTCGACGACCTGGCCCAGAGCCGCGCCGCGCTGGCCGCCATCGCCGCCGCCTGCCTTTGCCTGCTTGGC
GTCATCCTGAACGAACGGCGCCGCCACCTGCGTGACCGGCTGGCTGCCCGCGAAGCCCTGCAGCAGGCGCACGATGAACT
GGAACGCAAGGTTGAGGAACGCACCGCCGACCTGTCGTCCGCCAACCAGCAACTGCAGGACGAGGTCGGCGAACGCATCC
GCGCCGAGCGCACCCTGCGCGCCGCCCAGGACGAACTGGTGCAGGCCGGCAAGCTGGCAGTCATCGGCCAGCTGTCCACC
GGCATCGCCCACGAACTGAACCAGCCGCTGGCCGCGCTGCGCACGCTGTCGGCCAACGCCGAGCGCTTCCTGGAACGCGG
CGATGTCGACACCACGCGCACCAACCTCGGCCGCATTGCCGACCTGGTCGACCGCATGGGCCGGATCACCGGCCAGTTGC
GCAATTTCGCCCGCAAGTCGAGCGGCCAGTCGGCCCCAGTGCCACTTTGCCACGCGCTGGACAACGCGCTGGCCCTGCTC
GATGCCCGCATCCGCCGTGCCGGTGCCGAGATCGAGCGCAGCTGCCCGGTCGATGAGCCGGTCGCCCTGTGCGATGCCAA
CCGGCTGGAACAGGTGCTGATCAACCTGGTCGGCAACGCGCTCGACGCGATGGCCGACCAGACCCGCCCGCGCCTCGAAC
TGGCCTGGGAATGCGCGGAGGGCATGGTCCGCCTGCATGTCCGCGACCACGGTCCCGGTCTCAGTGACGAGGCGCTAGCC
CATCTGTTCGAACCCTTTTTCACCACCAAGCCGGCCGGCGATGGCCTCGGCTTGGGCCTGGCCATTTCCGCCGGCATCAT
CCGCGACTTCGGTGGTAGCCTGCACGGGGCCAACCACCCCGACGGTGGCGCCATCTTCACACTCGAACTCCCGCTCGCCC
CCGCGCCATGA

Upstream 100 bases:

>100_bases
AGCCTTCCTGGGCGTGGTCGTCGTGCTGATTGCCAAGCAACTGGCCGACCTCTTCGGCTGAGCGCGGTAACATAGTCCAT
CCTGCACCGTTCGCCACCCG

Downstream 100 bases:

>100_bases
CCGACGACCTGAAAATCCTGATCATCGAAGACGACCCCGATGTGGCGCTCGGCTGCGAGCAGGCGCTGCAACTCGAAGGA
CTGGCCGCCGAATGCGCCGG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 616; Mature: 615

Protein sequence:

>616_residues
MPRLRSLPLLLLCLLLVALSGFSAYRIAQRLGIADLQATGLHRLDLYAASLEREISKYAFLPGTLSLEPEVLDLLAGTAG
DSAAARVNGYLEKLNERAGTLSIYVMDTRGKVLATSNWRRPDSFLGEELSFRPYFREALESGNGRFFGIGTTRGEPGYYL
ASALTGDNGTLGVAVIKVSLEQLEKSWTTVEAPVLVADENGVVILSAVPGWKFTTLRPLDDSTRAAFDHTQQYNRRALQP
LGIKQIEDYDHGARLVRIAANGPETVSVYPVTGRFLEQSRTLPGTPWTLTVLSHLEQVDDLAQSRAALAAIAAACLCLLG
VILNERRRHLRDRLAAREALQQAHDELERKVEERTADLSSANQQLQDEVGERIRAERTLRAAQDELVQAGKLAVIGQLST
GIAHELNQPLAALRTLSANAERFLERGDVDTTRTNLGRIADLVDRMGRITGQLRNFARKSSGQSAPVPLCHALDNALALL
DARIRRAGAEIERSCPVDEPVALCDANRLEQVLINLVGNALDAMADQTRPRLELAWECAEGMVRLHVRDHGPGLSDEALA
HLFEPFFTTKPAGDGLGLGLAISAGIIRDFGGSLHGANHPDGGAIFTLELPLAPAP

Sequences:

>Translated_616_residues
MPRLRSLPLLLLCLLLVALSGFSAYRIAQRLGIADLQATGLHRLDLYAASLEREISKYAFLPGTLSLEPEVLDLLAGTAG
DSAAARVNGYLEKLNERAGTLSIYVMDTRGKVLATSNWRRPDSFLGEELSFRPYFREALESGNGRFFGIGTTRGEPGYYL
ASALTGDNGTLGVAVIKVSLEQLEKSWTTVEAPVLVADENGVVILSAVPGWKFTTLRPLDDSTRAAFDHTQQYNRRALQP
LGIKQIEDYDHGARLVRIAANGPETVSVYPVTGRFLEQSRTLPGTPWTLTVLSHLEQVDDLAQSRAALAAIAAACLCLLG
VILNERRRHLRDRLAAREALQQAHDELERKVEERTADLSSANQQLQDEVGERIRAERTLRAAQDELVQAGKLAVIGQLST
GIAHELNQPLAALRTLSANAERFLERGDVDTTRTNLGRIADLVDRMGRITGQLRNFARKSSGQSAPVPLCHALDNALALL
DARIRRAGAEIERSCPVDEPVALCDANRLEQVLINLVGNALDAMADQTRPRLELAWECAEGMVRLHVRDHGPGLSDEALA
HLFEPFFTTKPAGDGLGLGLAISAGIIRDFGGSLHGANHPDGGAIFTLELPLAPAP
>Mature_615_residues
PRLRSLPLLLLCLLLVALSGFSAYRIAQRLGIADLQATGLHRLDLYAASLEREISKYAFLPGTLSLEPEVLDLLAGTAGD
SAAARVNGYLEKLNERAGTLSIYVMDTRGKVLATSNWRRPDSFLGEELSFRPYFREALESGNGRFFGIGTTRGEPGYYLA
SALTGDNGTLGVAVIKVSLEQLEKSWTTVEAPVLVADENGVVILSAVPGWKFTTLRPLDDSTRAAFDHTQQYNRRALQPL
GIKQIEDYDHGARLVRIAANGPETVSVYPVTGRFLEQSRTLPGTPWTLTVLSHLEQVDDLAQSRAALAAIAAACLCLLGV
ILNERRRHLRDRLAAREALQQAHDELERKVEERTADLSSANQQLQDEVGERIRAERTLRAAQDELVQAGKLAVIGQLSTG
IAHELNQPLAALRTLSANAERFLERGDVDTTRTNLGRIADLVDRMGRITGQLRNFARKSSGQSAPVPLCHALDNALALLD
ARIRRAGAEIERSCPVDEPVALCDANRLEQVLINLVGNALDAMADQTRPRLELAWECAEGMVRLHVRDHGPGLSDEALAH
LFEPFFTTKPAGDGLGLGLAISAGIIRDFGGSLHGANHPDGGAIFTLELPLAPAP

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=272, Percent_Identity=29.4117647058824, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=30.4166666666667, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788393, Length=222, Percent_Identity=32.8828828828829, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1789149, Length=290, Percent_Identity=24.1379310344828, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87081816, Length=292, Percent_Identity=27.3972602739726, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1786912, Length=177, Percent_Identity=32.2033898305085, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66910; Mature: 66779

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLRSLPLLLLCLLLVALSGFSAYRIAQRLGIADLQATGLHRLDLYAASLEREISKYAF
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHEE
LPGTLSLEPEVLDLLAGTAGDSAAARVNGYLEKLNERAGTLSIYVMDTRGKVLATSNWRR
CCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEECCCCCC
PDSFLGEELSFRPYFREALESGNGRFFGIGTTRGEPGYYLASALTGDNGTLGVAVIKVSL
CHHHHCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEECCCCCEEHHHHHHHH
EQLEKSWTTVEAPVLVADENGVVILSAVPGWKFTTLRPLDDSTRAAFDHTQQYNRRALQP
HHHHHHCCEEECCEEEECCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCC
LGIKQIEDYDHGARLVRIAANGPETVSVYPVTGRFLEQSRTLPGTPWTLTVLSHLEQVDD
CCCHHHHCCCCCCEEEEEECCCCCEEEEEECCHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LAQSRAALAAIAAACLCLLGVILNERRRHLRDRLAAREALQQAHDELERKVEERTADLSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANQQLQDEVGERIRAERTLRAAQDELVQAGKLAVIGQLSTGIAHELNQPLAALRTLSANA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCHHHHHHHHHCCH
ERFLERGDVDTTRTNLGRIADLVDRMGRITGQLRNFARKSSGQSAPVPLCHALDNALALL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
DARIRRAGAEIERSCPVDEPVALCDANRLEQVLINLVGNALDAMADQTRPRLELAWECAE
HHHHHHHCCHHHHCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
GMVRLHVRDHGPGLSDEALAHLFEPFFTTKPAGDGLGLGLAISAGIIRDFGGSLHGANHP
CEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
DGGAIFTLELPLAPAP
CCCEEEEEEECCCCCC
>Mature Secondary Structure 
PRLRSLPLLLLCLLLVALSGFSAYRIAQRLGIADLQATGLHRLDLYAASLEREISKYAF
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHEE
LPGTLSLEPEVLDLLAGTAGDSAAARVNGYLEKLNERAGTLSIYVMDTRGKVLATSNWRR
CCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEECCCCCC
PDSFLGEELSFRPYFREALESGNGRFFGIGTTRGEPGYYLASALTGDNGTLGVAVIKVSL
CHHHHCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEECCCCCEEHHHHHHHH
EQLEKSWTTVEAPVLVADENGVVILSAVPGWKFTTLRPLDDSTRAAFDHTQQYNRRALQP
HHHHHHCCEEECCEEEECCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCC
LGIKQIEDYDHGARLVRIAANGPETVSVYPVTGRFLEQSRTLPGTPWTLTVLSHLEQVDD
CCCHHHHCCCCCCEEEEEECCCCCEEEEEECCHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LAQSRAALAAIAAACLCLLGVILNERRRHLRDRLAAREALQQAHDELERKVEERTADLSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANQQLQDEVGERIRAERTLRAAQDELVQAGKLAVIGQLSTGIAHELNQPLAALRTLSANA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCHHHHHHHHHCCH
ERFLERGDVDTTRTNLGRIADLVDRMGRITGQLRNFARKSSGQSAPVPLCHALDNALALL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
DARIRRAGAEIERSCPVDEPVALCDANRLEQVLINLVGNALDAMADQTRPRLELAWECAE
HHHHHHHCCHHHHCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
GMVRLHVRDHGPGLSDEALAHLFEPFFTTKPAGDGLGLGLAISAGIIRDFGGSLHGANHP
CEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
DGGAIFTLELPLAPAP
CCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3671068 [H]