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The map label for this gene is mphP [H]

Identifier: 71906010

GI number: 71906010

Start: 399946

End: 400995

Strand: Reverse

Name: mphP [H]

Synonym: Daro_0368

Alternate gene names: 71906010

Gene position: 400995-399946 (Counterclockwise)

Preceding gene: 71906011

Following gene: 71906009

Centisome position: 8.91

GC content: 64.95

Gene sequence:

>1050_bases
ATGGCTCGTATCATCATGCAACCCTCCGGCAAGTCCGTTGATTGCGCCTATGGCGATACCGTTCTGATGGCGCTCGAAAA
GGCCGGCTATGCCCTGCCCAACAACTGCCGCGCCGGCGCCTGCGGCGAATGCAAGGTCAAGGTCACCCAAGGCCAGTTCG
ACCAGGGCATGGTGCTCGACATGGCCCTCTCGCAGGACGAGCGCAAGCAGGGCTTCGGCCTGATGTGCATGGCCAAACCG
ATTTCCGAGGAGCTGACCATCGAATGGGGCACCGAGGATGCGAAGCCCAAACTCTTCCCCCCGCGCGAAGATGCGCTGTT
CGTCGTCACCGACAAGAAGCAGATCGCCGCCCGCGTCGTCGAGCTGCGCCTGCGCCCGGTCGGCCAGCCGATCCGCTACT
GGCCCGGCCAGTACGTCACGCTCGGCAACCCGCGCGCCGACATTCCGGCCCGCGCCTATTCCATTTCCAACGCCCCCCGT
CCCGACGGCGAACTGGTGCTGCAAGTCGCCCGTGCCGACAGCGGCGTGACCAGCAACTGGGTCCACGACACCCTGCAGGC
CGGCGATAACGTCAAGGTATCCGGCGCCTACGGCACTTTCATCGGCGACCCCTCGGTCGATACCCCGGTCCTCTGCATCG
CCGCCGGCACCGGCCTCGCCCCCGTGCTGGCGCTGGCCGAAGCCGCCCTGCGCCGTGGTTTCAAGAAGCCGGTGACCATG
CTCTTCTCGGCCCGCACCAAGGAAGACGTTTACAGCCAGGGCATGATGGCCTGGTGGCGGACCAAGCATCGCAATTTCGA
CTACAAGGTAACGTTGACCCGCGAAGAAGCCGACGGCTTCCTGAAAGGCCGCGTCGACGTCGTGCTGCCGCAACTGTTCA
AGGACCTGTCCAAGCACACCATCTTCATCGCCGGCAGCCCGGAGTTCGTCGATAGCTGCGTCGCTGCCGCCAAGGCCCAG
GGTGCATTGGATGAACTGATCCACACCGAAGGCTTCTTCGCCCAGCAGCAGCCGGTGGTGGCCGACGCCGACCATCTGCT
GCCGCTCTAA

Upstream 100 bases:

>100_bases
CTAAACCAGACCAGCGACTGTAATTTGCTCCGGCCGGCGCCCCCACAAGGGCGCCGGCCTTGCCGCAACAGAGAAACCAA
TTCCACTAGGGGAAGACAAA

Downstream 100 bases:

>100_bases
ATCACAAAAACAGACCCTCGAGGAGACGAAATGAACCCCCAAGACCAACAGAGAAGGAGGGCATGATGCTTGCCCAGTTC
CTGCAATTCCTCTTTTCCGG

Product: ferredoxin:oxidoreductase FAD/NAD(P)-binding:oxidoreductase FAD-binding region

Products: NA

Alternate protein names: Phenol 2-monooxygenase P5 component [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MARIIMQPSGKSVDCAYGDTVLMALEKAGYALPNNCRAGACGECKVKVTQGQFDQGMVLDMALSQDERKQGFGLMCMAKP
ISEELTIEWGTEDAKPKLFPPREDALFVVTDKKQIAARVVELRLRPVGQPIRYWPGQYVTLGNPRADIPARAYSISNAPR
PDGELVLQVARADSGVTSNWVHDTLQAGDNVKVSGAYGTFIGDPSVDTPVLCIAAGTGLAPVLALAEAALRRGFKKPVTM
LFSARTKEDVYSQGMMAWWRTKHRNFDYKVTLTREEADGFLKGRVDVVLPQLFKDLSKHTIFIAGSPEFVDSCVAAAKAQ
GALDELIHTEGFFAQQQPVVADADHLLPL

Sequences:

>Translated_349_residues
MARIIMQPSGKSVDCAYGDTVLMALEKAGYALPNNCRAGACGECKVKVTQGQFDQGMVLDMALSQDERKQGFGLMCMAKP
ISEELTIEWGTEDAKPKLFPPREDALFVVTDKKQIAARVVELRLRPVGQPIRYWPGQYVTLGNPRADIPARAYSISNAPR
PDGELVLQVARADSGVTSNWVHDTLQAGDNVKVSGAYGTFIGDPSVDTPVLCIAAGTGLAPVLALAEAALRRGFKKPVTM
LFSARTKEDVYSQGMMAWWRTKHRNFDYKVTLTREEADGFLKGRVDVVLPQLFKDLSKHTIFIAGSPEFVDSCVAAAKAQ
GALDELIHTEGFFAQQQPVVADADHLLPL
>Mature_348_residues
ARIIMQPSGKSVDCAYGDTVLMALEKAGYALPNNCRAGACGECKVKVTQGQFDQGMVLDMALSQDERKQGFGLMCMAKPI
SEELTIEWGTEDAKPKLFPPREDALFVVTDKKQIAARVVELRLRPVGQPIRYWPGQYVTLGNPRADIPARAYSISNAPRP
DGELVLQVARADSGVTSNWVHDTLQAGDNVKVSGAYGTFIGDPSVDTPVLCIAAGTGLAPVLALAEAALRRGFKKPVTML
FSARTKEDVYSQGMMAWWRTKHRNFDYKVTLTREEADGFLKGRVDVVLPQLFKDLSKHTIFIAGSPEFVDSCVAAAKAQG
ALDELIHTEGFFAQQQPVVADADHLLPL

Specific function: Probable electron transfer from NADPH, via FAD and the 2Fe-2S center, to the oxygenase activity site of the enzyme [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787098, Length=203, Percent_Identity=29.064039408867, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788903, Length=154, Percent_Identity=33.1168831168831, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787658, Length=218, Percent_Identity=27.0642201834862, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: =1.14.13.7 [H]

Molecular weight: Translated: 38059; Mature: 37928

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00178 AA_TRNA_LIGASE_I ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIIMQPSGKSVDCAYGDTVLMALEKAGYALPNNCRAGACGECKVKVTQGQFDQGMVLD
CCEEEECCCCCEEEECCCCHHEEHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEE
MALSQDERKQGFGLMCMAKPISEELTIEWGTEDAKPKLFPPREDALFVVTDKKQIAARVV
EECCCHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCHHHHHHHH
ELRLRPVGQPIRYWPGQYVTLGNPRADIPARAYSISNAPRPDGELVLQVARADSGVTSNW
HHHHCCCCCCHHHCCCCEEEECCCCCCCCCCEEECCCCCCCCHHHEEEEECCCCCCCHHH
VHDTLQAGDNVKVSGAYGTFIGDPSVDTPVLCIAAGTGLAPVLALAEAALRRGFKKPVTM
HHHHHHCCCCEEEEEECEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCHHH
LFSARTKEDVYSQGMMAWWRTKHRNFDYKVTLTREEADGFLKGRVDVVLPQLFKDLSKHT
HHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHCHHHHHHHHHHHHHHHCE
IFIAGSPEFVDSCVAAAKAQGALDELIHTEGFFAQQQPVVADADHLLPL
EEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCHHCCCC
>Mature Secondary Structure 
ARIIMQPSGKSVDCAYGDTVLMALEKAGYALPNNCRAGACGECKVKVTQGQFDQGMVLD
CEEEECCCCCEEEECCCCHHEEHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEE
MALSQDERKQGFGLMCMAKPISEELTIEWGTEDAKPKLFPPREDALFVVTDKKQIAARVV
EECCCHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCHHHHHHHH
ELRLRPVGQPIRYWPGQYVTLGNPRADIPARAYSISNAPRPDGELVLQVARADSGVTSNW
HHHHCCCCCCHHHCCCCEEEECCCCCCCCCCEEECCCCCCCCHHHEEEEECCCCCCCHHH
VHDTLQAGDNVKVSGAYGTFIGDPSVDTPVLCIAAGTGLAPVLALAEAALRRGFKKPVTM
HHHHHHCCCCEEEEEECEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCHHH
LFSARTKEDVYSQGMMAWWRTKHRNFDYKVTLTREEADGFLKGRVDVVLPQLFKDLSKHT
HHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHCHHHHHHHHHHHHHHHCE
IFIAGSPEFVDSCVAAAKAQGALDELIHTEGFFAQQQPVVADADHLLPL
EEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12732969 [H]