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The map label for this gene is dacC [H]

Identifier: 71905933

GI number: 71905933

Start: 332243

End: 333418

Strand: Reverse

Name: dacC [H]

Synonym: Daro_0291

Alternate gene names: 71905933

Gene position: 333418-332243 (Counterclockwise)

Preceding gene: 71905934

Following gene: 71905932

Centisome position: 7.41

GC content: 60.12

Gene sequence:

>1176_bases
ATGTCCTCCCCCAACGCAAAACAAAGTACAAACCCCATGTCGCTGTTCCGCAAGACCGCTTTCATCCTCCTCAGTATTGT
CACCGCTGGCCAGGCCATGGCCCAACAGCTTCCCGTCCCGCCTGCATTGGCCGCCAAATCCTGGCTGCTGCTGGAAGTCG
GTTCGAACCAGGTTTTGACCGCCGAAAAATCTGACGAGCGCCTCGAACCGGCCTCGCTAACCAAACTGATGACGGCCTAC
CTGACTTTCGCCGCCATCCGCCAGAAAACCATCGGCCTGAGCCAGACCCTGCCCGTCTCCGAAAAGGCCTGGCGCACCGG
CGGTTCGAAGATGTTCGTCCGGGTCGACACGCAAGTGCCGGTGGAAGACCTGATCAAGGGCATGATCGTCCAGTCCGGCA
ACGACGCCTGCGTCACGCTGGCCGAAGGCATCGCCGGCAGCGAAGAGAATTTCGCCCAGATGATGAACCGCGAAGCACAG
CGCCTGGGCATGACCAACAGTCACTTCATCAACTCGACCGGCCTGCCCGATCCGCAGCACTACACCACCGCCCGCGACCT
CTCCCTGCTCGCCTCCGCACTGATCCGCGACTTCCCCGAGGACTACAAGAAGTACTACTCGATGAAGGAATTCCGCTACA
ACAACATCACCCAGCCGAACCGCAACCGCCTGCTCTTCATCGATCCGACGGTTGATGGCGTCAAGACCGGCCACACCGAA
GCCGCCGGCTATTGCCTGATTTCCTCGGCCCTGCGCGACAAGCGCCGCCTGCTGTCGGTGGTGCTCGGCACGACCTCGGA
CAGCGCCCGCGCGACCGAATCGCAAAAGCTCTTGAACTGGGGCTTTATCTCCTACGACTCCGTGGCACTTTTTGCCAAGG
ATCAGGCTGTCGCCACCCTGCGCGTCTGGAAGGGCGCCCAGAGCGAGGTCAAGGCCGGCTTCACCAGTGATCTCGGCATT
GCGGTTCCGAAGGGCTATGCCGACAAGGTCAAGAGCGATTTCATCGCCGAGCCGCGCCTGATCGCCCCGGTCGAAGCGGG
CCAGAAAATCGGCACGCTGAAGGTCAGTATCGACGGCAAGCCGTACAACGAATATCCGGTCGTCGCTCTTGAAAATATCG
CACTCGGCAATATCTTCATTCGTATCATCGATACCATCCGACTCTGGTTCAACTAA

Upstream 100 bases:

>100_bases
AACAGATCTACGCGATCTCCAGCGAACGGCGCATCCGCCACCCGGCCGTCGAGGCGCTCTGCGCCGCAGCGCCGCAGGCC
GGCGCGGAGCCGAGGGTATA

Downstream 100 bases:

>100_bases
ACCCATGACACCCTACGTCGCCGATCCCGTCTACCTGAATGGCCGTTTCCTGCCGTTGGCGGAAGCGGGTATTTCCCCAC
TCGACCGGGGTTTTCTATAC

Product: penicillin-binding protein 6

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSSPNAKQSTNPMSLFRKTAFILLSIVTAGQAMAQQLPVPPALAAKSWLLLEVGSNQVLTAEKSDERLEPASLTKLMTAY
LTFAAIRQKTIGLSQTLPVSEKAWRTGGSKMFVRVDTQVPVEDLIKGMIVQSGNDACVTLAEGIAGSEENFAQMMNREAQ
RLGMTNSHFINSTGLPDPQHYTTARDLSLLASALIRDFPEDYKKYYSMKEFRYNNITQPNRNRLLFIDPTVDGVKTGHTE
AAGYCLISSALRDKRRLLSVVLGTTSDSARATESQKLLNWGFISYDSVALFAKDQAVATLRVWKGAQSEVKAGFTSDLGI
AVPKGYADKVKSDFIAEPRLIAPVEAGQKIGTLKVSIDGKPYNEYPVVALENIALGNIFIRIIDTIRLWFN

Sequences:

>Translated_391_residues
MSSPNAKQSTNPMSLFRKTAFILLSIVTAGQAMAQQLPVPPALAAKSWLLLEVGSNQVLTAEKSDERLEPASLTKLMTAY
LTFAAIRQKTIGLSQTLPVSEKAWRTGGSKMFVRVDTQVPVEDLIKGMIVQSGNDACVTLAEGIAGSEENFAQMMNREAQ
RLGMTNSHFINSTGLPDPQHYTTARDLSLLASALIRDFPEDYKKYYSMKEFRYNNITQPNRNRLLFIDPTVDGVKTGHTE
AAGYCLISSALRDKRRLLSVVLGTTSDSARATESQKLLNWGFISYDSVALFAKDQAVATLRVWKGAQSEVKAGFTSDLGI
AVPKGYADKVKSDFIAEPRLIAPVEAGQKIGTLKVSIDGKPYNEYPVVALENIALGNIFIRIIDTIRLWFN
>Mature_390_residues
SSPNAKQSTNPMSLFRKTAFILLSIVTAGQAMAQQLPVPPALAAKSWLLLEVGSNQVLTAEKSDERLEPASLTKLMTAYL
TFAAIRQKTIGLSQTLPVSEKAWRTGGSKMFVRVDTQVPVEDLIKGMIVQSGNDACVTLAEGIAGSEENFAQMMNREAQR
LGMTNSHFINSTGLPDPQHYTTARDLSLLASALIRDFPEDYKKYYSMKEFRYNNITQPNRNRLLFIDPTVDGVKTGHTEA
AGYCLISSALRDKRRLLSVVLGTTSDSARATESQKLLNWGFISYDSVALFAKDQAVATLRVWKGAQSEVKAGFTSDLGIA
VPKGYADKVKSDFIAEPRLIAPVEAGQKIGTLKVSIDGKPYNEYPVVALENIALGNIFIRIIDTIRLWFN

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=381, Percent_Identity=41.7322834645669, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1786851, Length=363, Percent_Identity=38.5674931129477, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI87082022, Length=356, Percent_Identity=38.4831460674157, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI87082054, Length=246, Percent_Identity=27.6422764227642, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 42950; Mature: 42819

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPNAKQSTNPMSLFRKTAFILLSIVTAGQAMAQQLPVPPALAAKSWLLLEVGSNQVLT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEECCCEEEE
AEKSDERLEPASLTKLMTAYLTFAAIRQKTIGLSQTLPVSEKAWRTGGSKMFVRVDTQVP
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEEEEEECCCC
VEDLIKGMIVQSGNDACVTLAEGIAGSEENFAQMMNREAQRLGMTNSHFINSTGLPDPQH
HHHHHHHHEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCH
YTTARDLSLLASALIRDFPEDYKKYYSMKEFRYNNITQPNRNRLLFIDPTVDGVKTGHTE
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCC
AAGYCLISSALRDKRRLLSVVLGTTSDSARATESQKLLNWGFISYDSVALFAKDQAVATL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEE
RVWKGAQSEVKAGFTSDLGIAVPKGYADKVKSDFIAEPRLIAPVEAGQKIGTLKVSIDGK
EECCCCHHHHHCCCCCCCCEECCCCHHHHHHHHHCCCCCEECCHHCCCCEEEEEEEECCC
PYNEYPVVALENIALGNIFIRIIDTIRLWFN
CCCCCCEEEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSPNAKQSTNPMSLFRKTAFILLSIVTAGQAMAQQLPVPPALAAKSWLLLEVGSNQVLT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEECCCEEEE
AEKSDERLEPASLTKLMTAYLTFAAIRQKTIGLSQTLPVSEKAWRTGGSKMFVRVDTQVP
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEEEEEECCCC
VEDLIKGMIVQSGNDACVTLAEGIAGSEENFAQMMNREAQRLGMTNSHFINSTGLPDPQH
HHHHHHHHEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCH
YTTARDLSLLASALIRDFPEDYKKYYSMKEFRYNNITQPNRNRLLFIDPTVDGVKTGHTE
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCC
AAGYCLISSALRDKRRLLSVVLGTTSDSARATESQKLLNWGFISYDSVALFAKDQAVATL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEE
RVWKGAQSEVKAGFTSDLGIAVPKGYADKVKSDFIAEPRLIAPVEAGQKIGTLKVSIDGK
EECCCCHHHHHCCCCCCCCEECCCCHHHHHHHHHCCCCCEECCHHCCCCEEEEEEEECCC
PYNEYPVVALENIALGNIFIRIIDTIRLWFN
CCCCCCEEEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]