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The map label for this gene is rcsC [H]

Identifier: 71905907

GI number: 71905907

Start: 306340

End: 308433

Strand: Reverse

Name: rcsC [H]

Synonym: Daro_0265

Alternate gene names: 71905907

Gene position: 308433-306340 (Counterclockwise)

Preceding gene: 71905908

Following gene: 71905905

Centisome position: 6.85

GC content: 62.23

Gene sequence:

>2094_bases
ATGCCCAGCAGAAAGCCCGAAACTCTCGCCCTGAGCATTGCACTGGTCGGCACGCTGGTGGTTTTGCTTGTTTTTCTGGC
CGACCTCGCCCTGGCACGACACCGCGACCTGGAATCCGGCGAACGTCGGCTCCAGCATTTCGGTCTGATGATGGCCGAGC
ATACCGCCCGGACTTTCGAAGCCGTCGACGTGCTGCTTCGCGAGACGGCAACCGATCTCTCGCACAGCCGCCGCGACTGG
GAAACGTGGGATACCAGCAAGGGCTGGGAATACATTGCCCAGCGCCATTCGCGGGCCATGCCGCAGCTGCGGGACCTGAT
CATTTTTGATCGGTATGGCAACCAGCGCTTTATCTCGACCTTCTTCCCGGCCCCCCACATCAACGTCAAGGACCGCCCCT
ATTTCATCGCGCTTGAGGATGGAGCTGAGTCCTCCACCTTCGGCCCCTATATCGGCCGCAACAGCGGGCGTTACACCTAC
GCCATCGCCCGCCGCCTGACCGGTGACAACGGACATTTTGCTGGCGTCGTCTTTGCGGCCATGGAGCCGGCCTATCTCCA
GGACTTCTGCTGGTCGAACCGGCTGTCCGACGATTTCGAAACCGTCCTCATCAACCAGAAAAGCGAAATCATCGCCTCCT
GCCGCCCCTCCGACCTCAGCCGGCAATCGCCGATTCTCGGCGCCCAGGCCGCAGCAGTCTTGTACGGTGGCCAACTAAAG
GGTTTCATTCCGGAGAATGGCTTGACCAGCGGCAACGGTTACCTGATCGCCGTATCCCAAGTCCCCGGCTTTACCGACCT
GCGAGTTCTCAGCGTGATCCCGGAAAAGACACTGCTGGCCGCCTGGCACAACCGCCTGTTCGAACTGGGTACGCTGGCTC
TGCTCGTCAGCATCGTCCTGCTCGTCACCGGACTGCTGGTTCGCCGCCAGGTTCGCGACATGGCGGCCATGACCGAGGAA
CTGGCGGCCAGCCACGATCTGCTCGAAGAACGCGTCCGCGAAGCTACCCAAGAGCTGGCCGGACAGAAGAATGCCGCCGA
ACGCGCCAACACGGCAAAGAGTCGCTTTCTCGCGGCGGCCAGTCACGACTTGCGCCAACCCTTGCATGCACTATCACTGT
TCGCCACTGACCTGCAGCGCCAGATTCGCAGCGGCACCCCGCAGGAGCTGCCCCGGCTGGCCGAACAAATATCAGCCTCG
ACGACCATTCTTGGCGAACTGCTCGATTCGCTGCTTGATATCTCCCGACTCGACGTCGCCGGCATCAAGCCCGATAGCCG
CCCAACCCCGTTGCAGCCGATCTTCGAGCGCCTCGCCAATTCCTTCCGGCGCGCCGCGACCGACCGCAATATGAGCTTGC
GTTTCCATCCGACCACGCGATGGGTGGAAACCGATCCGATCATGCTCGAACGCATGATCGCCAATCTGGTATCCAATGCC
TTGCGCTATACCCCGCCCGGCGGCAGCGTGCTGGTTGCCGCCCGCAACAGGGGCGACAGGGTGCTGATCGAAATCAGGGA
TAACGGTATCGGCATTGCCCCCCAACACCAGGCCGCCATTTTTGCCGAGTTCTACCAGGTCGGAAACACGGCCCGGGAAC
AGAACAAGGGGCTGGGATTGGGCCTGTCCATCGTCGATCGACTGGCCAAAGCGCTGGGGATCGAGGTAAAGCTCAACTCA
AGGCAGGGGGAAGGAACCAAGTTCACGCTCAGCGTAGCGAGCAGCCAGCCAGTTGTTGCCGGGCCGGCCGCAAGCGACAA
ACCGCCACAAGCCGGCAAGGTTCACTGCATCGGCACCTCGGAAGAGATGCTGTCCTGCATCGAACTGATGAAACGCTGGG
ACTATGCCGTCAGCAGCGATGATGGCAGCCGGACCGAGCGCCGGCCCGAAGATGCCGTATTGATCGCTGAACCCGAACTC
GCCGCCGCCGCCAGTGCCGAACTGGTGACCGGCATGCCCTTGGTTGTCCTGGTCCGTGACCCGGGCGCAAGCCTGCCGGC
CGGGGCTCACGCGCTGCCCGTACCAGTGCGCCCAGCCAAGCTGCGGGCGCTACTGAACCAGCTTCAGAAGACGCTTTCGA
AATCGATGCCGTAA

Upstream 100 bases:

>100_bases
TCAGCAACAGTTTTCCAGTACCCGGCATGACGCCCGAGCGGGTCATTGAGGTCGACTGCACGCCACCTCGGCCGCTCTAT
TGCTACCAGCTGTAGCCCGC

Downstream 100 bases:

>100_bases
CGGGCAACGGCAACCAGCGCTTGCGTCCGGCTGCTGACGCCTAGCGCCTTGAATACCGCCGTCGCATGGATCTTGACCGT
CCCCTCCGACAAGCCAAGCT

Product: sensor histidine kinase

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 697; Mature: 696

Protein sequence:

>697_residues
MPSRKPETLALSIALVGTLVVLLVFLADLALARHRDLESGERRLQHFGLMMAEHTARTFEAVDVLLRETATDLSHSRRDW
ETWDTSKGWEYIAQRHSRAMPQLRDLIIFDRYGNQRFISTFFPAPHINVKDRPYFIALEDGAESSTFGPYIGRNSGRYTY
AIARRLTGDNGHFAGVVFAAMEPAYLQDFCWSNRLSDDFETVLINQKSEIIASCRPSDLSRQSPILGAQAAAVLYGGQLK
GFIPENGLTSGNGYLIAVSQVPGFTDLRVLSVIPEKTLLAAWHNRLFELGTLALLVSIVLLVTGLLVRRQVRDMAAMTEE
LAASHDLLEERVREATQELAGQKNAAERANTAKSRFLAAASHDLRQPLHALSLFATDLQRQIRSGTPQELPRLAEQISAS
TTILGELLDSLLDISRLDVAGIKPDSRPTPLQPIFERLANSFRRAATDRNMSLRFHPTTRWVETDPIMLERMIANLVSNA
LRYTPPGGSVLVAARNRGDRVLIEIRDNGIGIAPQHQAAIFAEFYQVGNTAREQNKGLGLGLSIVDRLAKALGIEVKLNS
RQGEGTKFTLSVASSQPVVAGPAASDKPPQAGKVHCIGTSEEMLSCIELMKRWDYAVSSDDGSRTERRPEDAVLIAEPEL
AAAASAELVTGMPLVVLVRDPGASLPAGAHALPVPVRPAKLRALLNQLQKTLSKSMP

Sequences:

>Translated_697_residues
MPSRKPETLALSIALVGTLVVLLVFLADLALARHRDLESGERRLQHFGLMMAEHTARTFEAVDVLLRETATDLSHSRRDW
ETWDTSKGWEYIAQRHSRAMPQLRDLIIFDRYGNQRFISTFFPAPHINVKDRPYFIALEDGAESSTFGPYIGRNSGRYTY
AIARRLTGDNGHFAGVVFAAMEPAYLQDFCWSNRLSDDFETVLINQKSEIIASCRPSDLSRQSPILGAQAAAVLYGGQLK
GFIPENGLTSGNGYLIAVSQVPGFTDLRVLSVIPEKTLLAAWHNRLFELGTLALLVSIVLLVTGLLVRRQVRDMAAMTEE
LAASHDLLEERVREATQELAGQKNAAERANTAKSRFLAAASHDLRQPLHALSLFATDLQRQIRSGTPQELPRLAEQISAS
TTILGELLDSLLDISRLDVAGIKPDSRPTPLQPIFERLANSFRRAATDRNMSLRFHPTTRWVETDPIMLERMIANLVSNA
LRYTPPGGSVLVAARNRGDRVLIEIRDNGIGIAPQHQAAIFAEFYQVGNTAREQNKGLGLGLSIVDRLAKALGIEVKLNS
RQGEGTKFTLSVASSQPVVAGPAASDKPPQAGKVHCIGTSEEMLSCIELMKRWDYAVSSDDGSRTERRPEDAVLIAEPEL
AAAASAELVTGMPLVVLVRDPGASLPAGAHALPVPVRPAKLRALLNQLQKTLSKSMP
>Mature_696_residues
PSRKPETLALSIALVGTLVVLLVFLADLALARHRDLESGERRLQHFGLMMAEHTARTFEAVDVLLRETATDLSHSRRDWE
TWDTSKGWEYIAQRHSRAMPQLRDLIIFDRYGNQRFISTFFPAPHINVKDRPYFIALEDGAESSTFGPYIGRNSGRYTYA
IARRLTGDNGHFAGVVFAAMEPAYLQDFCWSNRLSDDFETVLINQKSEIIASCRPSDLSRQSPILGAQAAAVLYGGQLKG
FIPENGLTSGNGYLIAVSQVPGFTDLRVLSVIPEKTLLAAWHNRLFELGTLALLVSIVLLVTGLLVRRQVRDMAAMTEEL
AASHDLLEERVREATQELAGQKNAAERANTAKSRFLAAASHDLRQPLHALSLFATDLQRQIRSGTPQELPRLAEQISAST
TILGELLDSLLDISRLDVAGIKPDSRPTPLQPIFERLANSFRRAATDRNMSLRFHPTTRWVETDPIMLERMIANLVSNAL
RYTPPGGSVLVAARNRGDRVLIEIRDNGIGIAPQHQAAIFAEFYQVGNTAREQNKGLGLGLSIVDRLAKALGIEVKLNSR
QGEGTKFTLSVASSQPVVAGPAASDKPPQAGKVHCIGTSEEMLSCIELMKRWDYAVSSDDGSRTERRPEDAVLIAEPELA
AAASAELVTGMPLVVLVRDPGASLPAGAHALPVPVRPAKLRALLNQLQKTLSKSMP

Specific function: Member of the two-component regulatory system rcsC/rcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with rcsF, rcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=247, Percent_Identity=29.1497975708502, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=28.9256198347107, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI1789149, Length=294, Percent_Identity=27.5510204081633, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788713, Length=271, Percent_Identity=27.3062730627306, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1786783, Length=226, Percent_Identity=28.7610619469027, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI87081816, Length=277, Percent_Identity=31.0469314079422, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788393, Length=224, Percent_Identity=27.2321428571429, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1789403, Length=215, Percent_Identity=33.953488372093, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790346, Length=203, Percent_Identity=31.5270935960591, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790861, Length=250, Percent_Identity=26.8, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787894, Length=246, Percent_Identity=26.8292682926829, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=26.7543859649123, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87082128, Length=226, Percent_Identity=25.2212389380531, Blast_Score=73, Evalue=8e-14,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=25.6880733944954, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786912, Length=247, Percent_Identity=27.9352226720648, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1789808, Length=217, Percent_Identity=26.2672811059908, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76514; Mature: 76382

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSRKPETLALSIALVGTLVVLLVFLADLALARHRDLESGERRLQHFGLMMAEHTARTFE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AVDVLLRETATDLSHSRRDWETWDTSKGWEYIAQRHSRAMPQLRDLIIFDRYGNQRFIST
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHEEEEECCCCCEEEHH
FFPAPHINVKDRPYFIALEDGAESSTFGPYIGRNSGRYTYAIARRLTGDNGHFAGVVFAA
CCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEHHHHCCCCCCCHHHHHHH
MEPAYLQDFCWSNRLSDDFETVLINQKSEIIASCRPSDLSRQSPILGAQAAAVLYGGQLK
CCHHHHHHHHHCCCCCCCCHHEEECCHHHHHHCCCCCCCCCCCCCCCHHHHHHEECCCEE
GFIPENGLTSGNGYLIAVSQVPGFTDLRVLSVIPEKTLLAAWHNRLFELGTLALLVSIVL
CCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LVTGLLVRRQVRDMAAMTEELAASHDLLEERVREATQELAGQKNAAERANTAKSRFLAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SHDLRQPLHALSLFATDLQRQIRSGTPQELPRLAEQISASTTILGELLDSLLDISRLDVA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GIKPDSRPTPLQPIFERLANSFRRAATDRNMSLRFHPTTRWVETDPIMLERMIANLVSNA
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEECCCHHHHHHHHHHHHHHH
LRYTPPGGSVLVAARNRGDRVLIEIRDNGIGIAPQHQAAIFAEFYQVGNTAREQNKGLGL
HEECCCCCCEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHCCCCCC
GLSIVDRLAKALGIEVKLNSRQGEGTKFTLSVASSQPVVAGPAASDKPPQAGKVHCIGTS
CHHHHHHHHHHHCCEEEECCCCCCCCEEEEEECCCCCEEECCCCCCCCCCCCEEEEECCH
EEMLSCIELMKRWDYAVSSDDGSRTERRPEDAVLIAEPELAAAASAELVTGMPLVVLVRD
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCEEEEEEC
PGASLPAGAHALPVPVRPAKLRALLNQLQKTLSKSMP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PSRKPETLALSIALVGTLVVLLVFLADLALARHRDLESGERRLQHFGLMMAEHTARTFE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AVDVLLRETATDLSHSRRDWETWDTSKGWEYIAQRHSRAMPQLRDLIIFDRYGNQRFIST
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHEEEEECCCCCEEEHH
FFPAPHINVKDRPYFIALEDGAESSTFGPYIGRNSGRYTYAIARRLTGDNGHFAGVVFAA
CCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEHHHHCCCCCCCHHHHHHH
MEPAYLQDFCWSNRLSDDFETVLINQKSEIIASCRPSDLSRQSPILGAQAAAVLYGGQLK
CCHHHHHHHHHCCCCCCCCHHEEECCHHHHHHCCCCCCCCCCCCCCCHHHHHHEECCCEE
GFIPENGLTSGNGYLIAVSQVPGFTDLRVLSVIPEKTLLAAWHNRLFELGTLALLVSIVL
CCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LVTGLLVRRQVRDMAAMTEELAASHDLLEERVREATQELAGQKNAAERANTAKSRFLAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SHDLRQPLHALSLFATDLQRQIRSGTPQELPRLAEQISASTTILGELLDSLLDISRLDVA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GIKPDSRPTPLQPIFERLANSFRRAATDRNMSLRFHPTTRWVETDPIMLERMIANLVSNA
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEECCCHHHHHHHHHHHHHHH
LRYTPPGGSVLVAARNRGDRVLIEIRDNGIGIAPQHQAAIFAEFYQVGNTAREQNKGLGL
HEECCCCCCEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHCCCCCC
GLSIVDRLAKALGIEVKLNSRQGEGTKFTLSVASSQPVVAGPAASDKPPQAGKVHCIGTS
CHHHHHHHHHHHCCEEEECCCCCCCCEEEEEECCCCCEEECCCCCCCCCCCCEEEEECCH
EEMLSCIELMKRWDYAVSSDDGSRTERRPEDAVLIAEPELAAAASAELVTGMPLVVLVRD
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCEEEEEEC
PGASLPAGAHALPVPVRPAKLRALLNQLQKTLSKSMP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504; 8626298 [H]