Click here to switch to the map view.

The map label for this gene is crp [C]

Identifier: 71905890

GI number: 71905890

Start: 289817

End: 290491

Strand: Reverse

Name: crp [C]

Synonym: Daro_0248

Alternate gene names: 71905890

Gene position: 290491-289817 (Counterclockwise)

Preceding gene: 71905899

Following gene: 71905889

Centisome position: 6.45

GC content: 63.26

Gene sequence:

>675_bases
TTGAAGAACGCTGAGGAACTGCTTCGCACCTCCCTCTGGGGCCAGTCGCTGACAGCCGAGGAAATGGATCGCGCCCTGGC
CGGCACGATCGAGCGTTCTTTCGCGCCCGGCGCCTTCATCTGCATGAAGGGCGAGCCGGTCGATTACTGGATGGGCATCA
TCGACGGGCTGGGCAAGATGGCCAGCCACTGGACGACCGGCAAGACCACGTCGCTGACCGGCATCAGTGTCGGCGGCTGG
TTCGGCGAAGGCTCACTGATGAAGAAGGAGCCGCGGCGCTATGACGTGATGGCCCTGCGTGAAACCCGGGTCGCCTTCAT
GAGCCGCAACACCTTCAACTGGCTGCTCGACCACAGCATTCCGTTCAACCGCTACATGATCGCCCAGTTGAACGAGCGCC
TCGGCCAGTTCATCGGCATGATCGAGAACGAGCGCATGCTCGATACCGACGCCCGCATTGCCCGGGGCCTGGCGGCCCTG
TTCAACCCGGTGCTTTACCCCGGTACCAATCGCCTGCTGCAGATTTCTCAGGAAGAACTCGGCTACCTGGCCGGCGTCTC
CCGCCAGCGCGCCAACCAGGCGCTCAAGGTGCTGGAGGATGCCGGGCTGGTGCGCAGCGAATACGGCGGCATCCACATTG
TCGATCTGGAAGGCTTGCGCAGTTTCGGCGACTAG

Upstream 100 bases:

>100_bases
AAACCTTGCGCCGCACCACGACAATCTCTCACAGTTGCGGCTCAGTGTATGCACACCCCGAGCTTATAATTGTCATCCGG
CAGACATTCCAGGAAATAAA

Downstream 100 bases:

>100_bases
TTTTTCAAAAACAGGCCTCATGACGTTGCAATAACGTCAAATCGATATCACCAAATTCCCTGATCCACGCGGAACTGCTT
TGCCCGAATAGTTCATTGTC

Product: cyclic nucleotide-binding

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Transcriptional Regulator; Crp Family Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Regulatory Protein; CAMP-Dependent Transcriptional Regulator; Transcription Regulator Protein; Cyclic-Nucleotide-Gated Cation Channel; CNMP Regulatory Protein; HTH Crp Family Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; Transcriptional Regulator Crp Family

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MKNAEELLRTSLWGQSLTAEEMDRALAGTIERSFAPGAFICMKGEPVDYWMGIIDGLGKMASHWTTGKTTSLTGISVGGW
FGEGSLMKKEPRRYDVMALRETRVAFMSRNTFNWLLDHSIPFNRYMIAQLNERLGQFIGMIENERMLDTDARIARGLAAL
FNPVLYPGTNRLLQISQEELGYLAGVSRQRANQALKVLEDAGLVRSEYGGIHIVDLEGLRSFGD

Sequences:

>Translated_224_residues
MKNAEELLRTSLWGQSLTAEEMDRALAGTIERSFAPGAFICMKGEPVDYWMGIIDGLGKMASHWTTGKTTSLTGISVGGW
FGEGSLMKKEPRRYDVMALRETRVAFMSRNTFNWLLDHSIPFNRYMIAQLNERLGQFIGMIENERMLDTDARIARGLAAL
FNPVLYPGTNRLLQISQEELGYLAGVSRQRANQALKVLEDAGLVRSEYGGIHIVDLEGLRSFGD
>Mature_224_residues
MKNAEELLRTSLWGQSLTAEEMDRALAGTIERSFAPGAFICMKGEPVDYWMGIIDGLGKMASHWTTGKTTSLTGISVGGW
FGEGSLMKKEPRRYDVMALRETRVAFMSRNTFNWLLDHSIPFNRYMIAQLNERLGQFIGMIENERMLDTDARIARGLAAL
FNPVLYPGTNRLLQISQEELGYLAGVSRQRANQALKVLEDAGLVRSEYGGIHIVDLEGLRSFGD

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25071; Mature: 25071

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNAEELLRTSLWGQSLTAEEMDRALAGTIERSFAPGAFICMKGEPVDYWMGIIDGLGKM
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHH
ASHWTTGKTTSLTGISVGGWFGEGSLMKKEPRRYDVMALRETRVAFMSRNTFNWLLDHSI
HHCCCCCCCCEECEEEECCEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHEEECCCC
PFNRYMIAQLNERLGQFIGMIENERMLDTDARIARGLAALFNPVLYPGTNRLLQISQEEL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHEEECHHHH
GYLAGVSRQRANQALKVLEDAGLVRSEYGGIHIVDLEGLRSFGD
HHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEEHHHHHCCCC
>Mature Secondary Structure
MKNAEELLRTSLWGQSLTAEEMDRALAGTIERSFAPGAFICMKGEPVDYWMGIIDGLGKM
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHH
ASHWTTGKTTSLTGISVGGWFGEGSLMKKEPRRYDVMALRETRVAFMSRNTFNWLLDHSI
HHCCCCCCCCEECEEEECCEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHEEECCCC
PFNRYMIAQLNERLGQFIGMIENERMLDTDARIARGLAALFNPVLYPGTNRLLQISQEEL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHEEECHHHH
GYLAGVSRQRANQALKVLEDAGLVRSEYGGIHIVDLEGLRSFGD
HHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEEHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA