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The map label for this gene is metX

Identifier: 71905772

GI number: 71905772

Start: 143172

End: 144296

Strand: Reverse

Name: metX

Synonym: Daro_0130

Alternate gene names: 71905772

Gene position: 144296-143172 (Counterclockwise)

Preceding gene: 71905775

Following gene: 71905771

Centisome position: 3.21

GC content: 59.73

Gene sequence:

>1125_bases
ATGCCAGGACAATCCGTCGGCGCCGTCCAGCCACAGCGCGCCCACTTCGACCAGCCACTGCATTTGCGCAGCGGCGGGGT
TCTGCCGGCCTACGATCTGGTCTACGAGACCTACGGCACGCTCAATGCAGCCAAGTCGAATGCCATTCTCGTCTGCCACG
CCCTTTCCGGTCATCATCATGTGGCCGGCCACTATGCGGATCAGCCCGACAACATCGGCTGGTGGGACAACATCGTCGGC
CCCGGCCGACCACTCGATACCGATAAATTCTTCATTGTCGGCCTGAACAACCTCGGCGGCTGTCATGGCTCGACCGGTCC
GTCATCGCTCAATCCAGCGACAGGCAAACCCTGGGGTGCCGACTTCCCGATCGTTGCCGTCAATGACTGGGTCCATGCCC
AGGCAAGATTGGCTGACCTGCTCGGCATCGACAGCTGGGCTGCCGTCATGGGTGGCAGTCTGGGCGGCATGCAGGCCCTG
CGCTGGAGCATCACCTTCCCGGAGCGGGTGCGCAACGCCATCGTGATTGCCGCTGCCCCCAAGCTCTCGGCGCAGAACAT
CGCCTTCAATGACGTCGCCCGCCAGGCCATCCTGACCGACCCTGATTTCCACGGCGGCCACTACTACGAACATAACACCC
GACCAGTCCGTGGCTTGCGGCTGGCGCGCATGCTCGGCCATATCACCTACCTGTCCGATGACCAGATGGGCGAAAAATTT
GGCCGTGAACTGCGCAACAGCGCCTTTTCCTTCGGCTATGGCGTCGAATTCGAGGTCGAATCGTATTTGCGCTACCAGGG
CGACAAATTTGCCGGTTACTTCGACGCCAATACCTATCTCTTGATGACCAAGGCACTCGATTACTTCGATCCGTCCCGAG
AAGATGATGGCAACCTGACTGCCACCATGGCACGTACGCAGGCCAATTTCCTGATTGCCTCATTCACCACCGACTGGCGA
TTCACCCCGGCACGCTCCAAGGAAATCGTCGCCGCGCTGCTCGCCAATGGACGCAATGTGTCCTACGCTGAAATTGACCT
GAATTTCGGCCACGACTCTTTCCTGATGGAAGATGCCCACTATCACGGCGTCGTCGACGCCTATCTGCGGAACATCAAGC
TATGA

Upstream 100 bases:

>100_bases
CGATTTGAGCTCTGATTGCGGGCGCTTATAAATACAGCTAAAACGGGAACCACCCAGTTCGCGTTTTTCAGCCAACTGGG
TTTTTGTTTTCAGGAACAGC

Downstream 100 bases:

>100_bases
CGCATACCTTGGGCCGCCCCGATTTTGAAGTCATTGCCGGCTGGGTTGAACCGGGCCATCGCGTCCTCGACCTCGGCTGC
GGCGATGGCACGCTACTCAA

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MPGQSVGAVQPQRAHFDQPLHLRSGGVLPAYDLVYETYGTLNAAKSNAILVCHALSGHHHVAGHYADQPDNIGWWDNIVG
PGRPLDTDKFFIVGLNNLGGCHGSTGPSSLNPATGKPWGADFPIVAVNDWVHAQARLADLLGIDSWAAVMGGSLGGMQAL
RWSITFPERVRNAIVIAAAPKLSAQNIAFNDVARQAILTDPDFHGGHYYEHNTRPVRGLRLARMLGHITYLSDDQMGEKF
GRELRNSAFSFGYGVEFEVESYLRYQGDKFAGYFDANTYLLMTKALDYFDPSREDDGNLTATMARTQANFLIASFTTDWR
FTPARSKEIVAALLANGRNVSYAEIDLNFGHDSFLMEDAHYHGVVDAYLRNIKL

Sequences:

>Translated_374_residues
MPGQSVGAVQPQRAHFDQPLHLRSGGVLPAYDLVYETYGTLNAAKSNAILVCHALSGHHHVAGHYADQPDNIGWWDNIVG
PGRPLDTDKFFIVGLNNLGGCHGSTGPSSLNPATGKPWGADFPIVAVNDWVHAQARLADLLGIDSWAAVMGGSLGGMQAL
RWSITFPERVRNAIVIAAAPKLSAQNIAFNDVARQAILTDPDFHGGHYYEHNTRPVRGLRLARMLGHITYLSDDQMGEKF
GRELRNSAFSFGYGVEFEVESYLRYQGDKFAGYFDANTYLLMTKALDYFDPSREDDGNLTATMARTQANFLIASFTTDWR
FTPARSKEIVAALLANGRNVSYAEIDLNFGHDSFLMEDAHYHGVVDAYLRNIKL
>Mature_373_residues
PGQSVGAVQPQRAHFDQPLHLRSGGVLPAYDLVYETYGTLNAAKSNAILVCHALSGHHHVAGHYADQPDNIGWWDNIVGP
GRPLDTDKFFIVGLNNLGGCHGSTGPSSLNPATGKPWGADFPIVAVNDWVHAQARLADLLGIDSWAAVMGGSLGGMQALR
WSITFPERVRNAIVIAAAPKLSAQNIAFNDVARQAILTDPDFHGGHYYEHNTRPVRGLRLARMLGHITYLSDDQMGEKFG
RELRNSAFSFGYGVEFEVESYLRYQGDKFAGYFDANTYLLMTKALDYFDPSREDDGNLTATMARTQANFLIASFTTDWRF
TPARSKEIVAALLANGRNVSYAEIDLNFGHDSFLMEDAHYHGVVDAYLRNIKL

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=235, Percent_Identity=37.4468085106383, Blast_Score=158, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_DECAR (Q47JU2)

Other databases:

- EMBL:   CP000089
- RefSeq:   YP_283359.1
- ProteinModelPortal:   Q47JU2
- SMR:   Q47JU2
- STRING:   Q47JU2
- GeneID:   3569536
- GenomeReviews:   CP000089_GR
- KEGG:   dar:Daro_0130
- NMPDR:   fig|159087.4.peg.234
- eggNOG:   COG2021
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- ProtClustDB:   PRK00175
- BioCyc:   DARO159087:DARO_0130-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 41192; Mature: 41060

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: ACT_SITE 153-153 ACT_SITE 351-351

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGQSVGAVQPQRAHFDQPLHLRSGGVLPAYDLVYETYGTLNAAKSNAILVCHALSGHHH
CCCCCCCCCCCHHHCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCEE
VAGHYADQPDNIGWWDNIVGPGRPLDTDKFFIVGLNNLGGCHGSTGPSSLNPATGKPWGA
EECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
DFPIVAVNDWVHAQARLADLLGIDSWAAVMGGSLGGMQALRWSITFPERVRNAIVIAAAP
CCCEEEECCHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEEEEEECHHHHCCEEEEEECC
KLSAQNIAFNDVARQAILTDPDFHGGHYYEHNTRPVRGLRLARMLGHITYLSDDQMGEKF
CCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHEEECCCHHHHHH
GRELRNSAFSFGYGVEFEVESYLRYQGDKFAGYFDANTYLLMTKALDYFDPSREDDGNLT
HHHHHHHHHCCCCCEEEEHHHHHHHCCCCEEEEECCCEEEEEEEHHHHCCCCCCCCCCEE
ATMARTQANFLIASFTTDWRFTPARSKEIVAALLANGRNVSYAEIDLNFGHDSFLMEDAH
EEEEECCCCEEEEEECCCCEECCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCEEECCCH
YHGVVDAYLRNIKL
HHHHHHHHHHHCCC
>Mature Secondary Structure 
PGQSVGAVQPQRAHFDQPLHLRSGGVLPAYDLVYETYGTLNAAKSNAILVCHALSGHHH
CCCCCCCCCCHHHCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCEE
VAGHYADQPDNIGWWDNIVGPGRPLDTDKFFIVGLNNLGGCHGSTGPSSLNPATGKPWGA
EECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
DFPIVAVNDWVHAQARLADLLGIDSWAAVMGGSLGGMQALRWSITFPERVRNAIVIAAAP
CCCEEEECCHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEEEEEECHHHHCCEEEEEECC
KLSAQNIAFNDVARQAILTDPDFHGGHYYEHNTRPVRGLRLARMLGHITYLSDDQMGEKF
CCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHEEECCCHHHHHH
GRELRNSAFSFGYGVEFEVESYLRYQGDKFAGYFDANTYLLMTKALDYFDPSREDDGNLT
HHHHHHHHHCCCCCEEEEHHHHHHHCCCCEEEEECCCEEEEEEEHHHHCCCCCCCCCCEE
ATMARTQANFLIASFTTDWRFTPARSKEIVAALLANGRNVSYAEIDLNFGHDSFLMEDAH
EEEEECCCCEEEEEECCCCEECCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCEEECCCH
YHGVVDAYLRNIKL
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA