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The map label for this gene is spxA [H]

Identifier: 71911611

GI number: 71911611

Start: 1765340

End: 1765738

Strand: Reverse

Name: spxA [H]

Synonym: M5005_Spy_1798

Alternate gene names: 71911611

Gene position: 1765738-1765340 (Counterclockwise)

Preceding gene: 71911612

Following gene: 71911610

Centisome position: 96.04

GC content: 35.59

Gene sequence:

>399_bases
ATGATTAAAATTTACACGATTTCAAGTTGTACGAGCTGCAAGAAAGCCAAAACTTGGCTAAATGCCCATAAGCTTGCTTA
TAAAGAACAGAACTTAGGAAAAGAACCGCTAACTAAAGAAGAAATTTTAGCAATTTTATCAAAAACCGAAAATGGAGTGG
AGAGCATTGTTTCATCTAAAAATCGTTATGCCAAAGCTCTCGATTGCGATATTGAAGAATTAAGTGTTAGTGAGGTTATT
GATTTGATTCAAGATAACCCGCGCATCCTTAAAAGTCCCATTTTGATTGATGATAAACGTCTGCAAGTAGGCTACAAAGA
AGACGATATTCGTGCTTTTTTACCTCGCTCTATTCGTAATATTGAAAATACTGAAGCACGATTACGTGCTGCACTCTAA

Upstream 100 bases:

>100_bases
ATATCTTTAAAATTAAAAAAATAGGTCCAAAGACCTATATTTATAGATAAGAAACTGTGCTACAATAAAGCTATCACGAA
ATAGAAAGTGAGTCAGCAAC

Downstream 100 bases:

>100_bases
AAGCTCTTGTAGAGCTTTTTTTAAATACCTTCTTCGCTTGAAATTCTTGTTTATTTAATAGAAATAAGCTATAATAAAGC
ATAGCACTTAATTTTAGAAA

Product: Spx family transcriptional regulator

Products: NA

Alternate protein names: Thermoresistant insertional mutant protein A [H]

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MIKIYTISSCTSCKKAKTWLNAHKLAYKEQNLGKEPLTKEEILAILSKTENGVESIVSSKNRYAKALDCDIEELSVSEVI
DLIQDNPRILKSPILIDDKRLQVGYKEDDIRAFLPRSIRNIENTEARLRAAL

Sequences:

>Translated_132_residues
MIKIYTISSCTSCKKAKTWLNAHKLAYKEQNLGKEPLTKEEILAILSKTENGVESIVSSKNRYAKALDCDIEELSVSEVI
DLIQDNPRILKSPILIDDKRLQVGYKEDDIRAFLPRSIRNIENTEARLRAAL
>Mature_132_residues
MIKIYTISSCTSCKKAKTWLNAHKLAYKEQNLGKEPLTKEEILAILSKTENGVESIVSSKNRYAKALDCDIEELSVSEVI
DLIQDNPRILKSPILIDDKRLQVGYKEDDIRAFLPRSIRNIENTEARLRAAL

Specific function: Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes invo

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family. Spx subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335
- InterPro:   IPR006504 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: NA

Molecular weight: Translated: 15005; Mature: 15005

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKIYTISSCTSCKKAKTWLNAHKLAYKEQNLGKEPLTKEEILAILSKTENGVESIVSSK
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHCH
NRYAKALDCDIEELSVSEVIDLIQDNPRILKSPILIDDKRLQVGYKEDDIRAFLPRSIRN
HHHHHHHCCCHHHHCHHHHHHHHCCCCCHHCCCCEECCCEEECCCCCCHHHHHHHHHHHC
IENTEARLRAAL
CCHHHHHHHHCC
>Mature Secondary Structure
MIKIYTISSCTSCKKAKTWLNAHKLAYKEQNLGKEPLTKEEILAILSKTENGVESIVSSK
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHCH
NRYAKALDCDIEELSVSEVIDLIQDNPRILKSPILIDDKRLQVGYKEDDIRAFLPRSIRN
HHHHHHHCCCHHHHCHHHHHHHHCCCCCHHCCCCEECCCEEECCCCCCHHHHHHHHHHHC
IENTEARLRAAL
CCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471; 10048028 [H]