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The map label for this gene is pepO

Identifier: 71911595

GI number: 71911595

Start: 1748180

End: 1750075

Strand: Reverse

Name: pepO

Synonym: M5005_Spy_1782

Alternate gene names: NA

Gene position: 1750075-1748180 (Counterclockwise)

Preceding gene: 71911596

Following gene: 71911592

Centisome position: 95.19

GC content: 41.56

Gene sequence:

>1896_bases
ATGACAACTTATCAAGATGATTTTTACCAGGCTGTGAATGGAAAGTGGGCTGAAACAGCAGTTATTCCAGACGACAAGCC
TCGAACAGGTGGATTTTCAGACTTAGCAGATGAAATTGAGGCATTAATGCTAGACACTACAGATGCTTGGCTAGCTGGAG
AAAATATCCCTGATGATGCTATTTTAAAAAATTTTGTGAAATTCCATCGTTTGGTGGCTGACTACGCTAAACGTGATGAA
GTTGGAGTAAGTCCAATTCTCCCTTTAATTGAAGAATATCAGTCCTTAAAATCTTTTTCAGAATTTGTTGCTAATATAGC
GAAATATGAATTGGCAGGTTTACCAAATGAATTTCCCTTTAGTGTGGCACCAGACTTTATGAATGCTCAGCTGAATGTGC
TTTGGGCAGAAGCACCAAGCATTCTTTTGCCAGATACAACATACTACGAAGAAGGCAACGAAAAAGCTGAGGAATTGCGT
GGTATTTGGCGTCAGTCGCAAGAAAAGCTTTTACCTCAATTTGGTTTTTCAACAGAAGAAATCAAGGATCTTTTGGATAA
GGTAATTGAGCTAGATAAGCAATTGGCCAAGTATGTCTTGTCTCGTGAGGAAGGCTCAGAATATGCCAAATTATACCATC
CTTATGTGTGGGCTGATTTTAAAAAACTAGCTCCAGAGCTTCCTTTGGATAGCATTTTTGAAAAGATTTTAGGCCAAGTA
CCTGACAAGGTTATTGTTCCTGAGGAACGTTTTTGGACAGAATTTGCAGCCACTTATTACTCTGAAGCCAATTGGGATTT
ACTCAAGGCTAATTTGATTGTGGACGCGGCTAATGCTTACAATGCTTACTTGACGGATGATATTCGTGTGGAATCAGGCG
CTTATTCGCGCGCTCTTTCAGGAACACCTCAAGCTATGGACAAACAAAAAGCAGCCTTTTATTTGGCGCAAGGACCGTTT
AGCCAAGCGCTTGGCTTGTGGTATGCTGGTCAAAAATTCTCCCCAGAAGCTAAGGCTGATGTGGAAAGTAAGGTAGCACG
CATGATTGAGGTTTATAAGTCTCGTCTAGAAACGGCTGATTGGTTAGCACCAGCCACACGTGAAAAAGCCATTACTAAAT
TAAATGTTATCACGCCACATATTGGTTACCCAGAAAAATTACCAGAAACCTATGCTAAAAAAGTGATTGATGAGAGCTTG
TCATTGGTTGAAAATGCACAGAACTTGGCTAAAATCACGATTGCTCACACTTGGAGTAAATGGAACAAGCCAGTTGACCG
TAGTGAATGGCATATGCCAGCCCACTTAGTCAATGCTTATTATGATCCTCAGCAAAATCAGATTGTCTTTCCTGCGGCAA
TCTTACAAGAGCCATTTTATTCTTTAGATCAGAGTTCTTCAGCCAATTATGGAGGAATTGGTGCAGTCATTGCGCATGAG
ATTTCACATGCCTTTGACACCAATGGTGCTTCCTTTGATGAACATGGTAGCCTAAATGATTGGTGGACACAAGAAGACTA
TGCTGCCTTTAAAGAGCGCACAGATAAGATTGTGGCGCAGTTTGACGGCTTAGAGTCACATGGTGCTAAGGTCAATGGTA
AATTGACAGTTTCAGAAAACGTCGCTGATCTAGGTGGGGTAGCTTGTGCTTTAGAAGCGGCACAATCAGAAGAAGACTTC
TCAGCCCGTGACTTCTTTATTAACTTTGCGACGATTTGGCGTATGAAGGCCCGTGAGGAATACATGCAAATGCTAGCTAG
CATTGATGTTCATGCTCCGGGTGAACTGCGAACAAATGTCACCTTAACCAACTTTGATGCTTTCCATGAGACCTTTGATA
TTAAAGAAGGCGATGCTATGTGGAGAGCTCCGAAAGACCGTGTGATTATTTGGTAA

Upstream 100 bases:

>100_bases
AGATAAGTTATTTTAGCTAAATTTTGGTACAATGGAAAAGATTATAAGTAGAGTTTAAGATAAAGATTCTACAAATTTAA
AATGATATAAGGAGATACGA

Downstream 100 bases:

>100_bases
TTAGGTAGTTGATAAACCTTCAAATGCCTGTGATTATAAAAATGACTGATTCTGTGAAACACAGGATCAGTTTTTTGCTT
CCTTATTGGTGTCCGTTTTG

Product: neutral endopeptidase

Products: NA

Alternate protein names: ORF6 [H]

Number of amino acids: Translated: 631; Mature: 630

Protein sequence:

>631_residues
MTTYQDDFYQAVNGKWAETAVIPDDKPRTGGFSDLADEIEALMLDTTDAWLAGENIPDDAILKNFVKFHRLVADYAKRDE
VGVSPILPLIEEYQSLKSFSEFVANIAKYELAGLPNEFPFSVAPDFMNAQLNVLWAEAPSILLPDTTYYEEGNEKAEELR
GIWRQSQEKLLPQFGFSTEEIKDLLDKVIELDKQLAKYVLSREEGSEYAKLYHPYVWADFKKLAPELPLDSIFEKILGQV
PDKVIVPEERFWTEFAATYYSEANWDLLKANLIVDAANAYNAYLTDDIRVESGAYSRALSGTPQAMDKQKAAFYLAQGPF
SQALGLWYAGQKFSPEAKADVESKVARMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYAKKVIDESL
SLVENAQNLAKITIAHTWSKWNKPVDRSEWHMPAHLVNAYYDPQQNQIVFPAAILQEPFYSLDQSSSANYGGIGAVIAHE
ISHAFDTNGASFDEHGSLNDWWTQEDYAAFKERTDKIVAQFDGLESHGAKVNGKLTVSENVADLGGVACALEAAQSEEDF
SARDFFINFATIWRMKAREEYMQMLASIDVHAPGELRTNVTLTNFDAFHETFDIKEGDAMWRAPKDRVIIW

Sequences:

>Translated_631_residues
MTTYQDDFYQAVNGKWAETAVIPDDKPRTGGFSDLADEIEALMLDTTDAWLAGENIPDDAILKNFVKFHRLVADYAKRDE
VGVSPILPLIEEYQSLKSFSEFVANIAKYELAGLPNEFPFSVAPDFMNAQLNVLWAEAPSILLPDTTYYEEGNEKAEELR
GIWRQSQEKLLPQFGFSTEEIKDLLDKVIELDKQLAKYVLSREEGSEYAKLYHPYVWADFKKLAPELPLDSIFEKILGQV
PDKVIVPEERFWTEFAATYYSEANWDLLKANLIVDAANAYNAYLTDDIRVESGAYSRALSGTPQAMDKQKAAFYLAQGPF
SQALGLWYAGQKFSPEAKADVESKVARMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYAKKVIDESL
SLVENAQNLAKITIAHTWSKWNKPVDRSEWHMPAHLVNAYYDPQQNQIVFPAAILQEPFYSLDQSSSANYGGIGAVIAHE
ISHAFDTNGASFDEHGSLNDWWTQEDYAAFKERTDKIVAQFDGLESHGAKVNGKLTVSENVADLGGVACALEAAQSEEDF
SARDFFINFATIWRMKAREEYMQMLASIDVHAPGELRTNVTLTNFDAFHETFDIKEGDAMWRAPKDRVIIW
>Mature_630_residues
TTYQDDFYQAVNGKWAETAVIPDDKPRTGGFSDLADEIEALMLDTTDAWLAGENIPDDAILKNFVKFHRLVADYAKRDEV
GVSPILPLIEEYQSLKSFSEFVANIAKYELAGLPNEFPFSVAPDFMNAQLNVLWAEAPSILLPDTTYYEEGNEKAEELRG
IWRQSQEKLLPQFGFSTEEIKDLLDKVIELDKQLAKYVLSREEGSEYAKLYHPYVWADFKKLAPELPLDSIFEKILGQVP
DKVIVPEERFWTEFAATYYSEANWDLLKANLIVDAANAYNAYLTDDIRVESGAYSRALSGTPQAMDKQKAAFYLAQGPFS
QALGLWYAGQKFSPEAKADVESKVARMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYAKKVIDESLS
LVENAQNLAKITIAHTWSKWNKPVDRSEWHMPAHLVNAYYDPQQNQIVFPAAILQEPFYSLDQSSSANYGGIGAVIAHEI
SHAFDTNGASFDEHGSLNDWWTQEDYAAFKERTDKIVAQFDGLESHGAKVNGKLTVSENVADLGGVACALEAAQSEEDFS
ARDFFINFATIWRMKAREEYMQMLASIDVHAPGELRTNVTLTNFDAFHETFDIKEGDAMWRAPKDRVIIW

Specific function: Unknown

COG id: COG3590

COG function: function code O; Predicted metalloendopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M13 family [H]

Homologues:

Organism=Homo sapiens, GI116256333, Length=698, Percent_Identity=28.5100286532951, Blast_Score=236, Evalue=4e-62,
Organism=Homo sapiens, GI116256331, Length=698, Percent_Identity=28.5100286532951, Blast_Score=236, Evalue=4e-62,
Organism=Homo sapiens, GI116256329, Length=698, Percent_Identity=28.5100286532951, Blast_Score=236, Evalue=4e-62,
Organism=Homo sapiens, GI116256327, Length=698, Percent_Identity=28.5100286532951, Blast_Score=236, Evalue=4e-62,
Organism=Homo sapiens, GI239049391, Length=681, Percent_Identity=27.9001468428781, Blast_Score=232, Evalue=8e-61,
Organism=Homo sapiens, GI157426891, Length=661, Percent_Identity=26.3237518910741, Blast_Score=228, Evalue=2e-59,
Organism=Homo sapiens, GI164519136, Length=662, Percent_Identity=25.9818731117825, Blast_Score=213, Evalue=5e-55,
Organism=Homo sapiens, GI4503443, Length=662, Percent_Identity=25.9818731117825, Blast_Score=213, Evalue=6e-55,
Organism=Homo sapiens, GI164519138, Length=662, Percent_Identity=25.9818731117825, Blast_Score=213, Evalue=6e-55,
Organism=Homo sapiens, GI164519140, Length=662, Percent_Identity=25.9818731117825, Blast_Score=212, Evalue=8e-55,
Organism=Homo sapiens, GI153945761, Length=667, Percent_Identity=25.9370314842579, Blast_Score=202, Evalue=7e-52,
Organism=Homo sapiens, GI82617560, Length=668, Percent_Identity=26.0479041916168, Blast_Score=202, Evalue=8e-52,
Organism=Homo sapiens, GI153945836, Length=667, Percent_Identity=25.9370314842579, Blast_Score=202, Evalue=1e-51,
Organism=Homo sapiens, GI153945771, Length=667, Percent_Identity=25.9370314842579, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI90403592, Length=366, Percent_Identity=27.0491803278689, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI4557691, Length=337, Percent_Identity=24.3323442136499, Blast_Score=84, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI86562497, Length=686, Percent_Identity=24.9271137026239, Blast_Score=202, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI17533333, Length=674, Percent_Identity=23.7388724035608, Blast_Score=181, Evalue=8e-46,
Organism=Caenorhabditis elegans, GI25148650, Length=704, Percent_Identity=25.7102272727273, Blast_Score=181, Evalue=8e-46,
Organism=Caenorhabditis elegans, GI71987442, Length=671, Percent_Identity=24.8882265275708, Blast_Score=177, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI32563993, Length=584, Percent_Identity=24.486301369863, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17564342, Length=303, Percent_Identity=32.6732673267327, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17534401, Length=319, Percent_Identity=28.8401253918495, Blast_Score=141, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI17570047, Length=347, Percent_Identity=23.0547550432277, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71988640, Length=318, Percent_Identity=27.3584905660377, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17533319, Length=297, Percent_Identity=26.5993265993266, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71994787, Length=288, Percent_Identity=24.6527777777778, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71998977, Length=313, Percent_Identity=27.4760383386581, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71998975, Length=313, Percent_Identity=27.4760383386581, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17532485, Length=313, Percent_Identity=26.1980830670927, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193204436, Length=302, Percent_Identity=22.8476821192053, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24643425, Length=669, Percent_Identity=26.1584454409567, Blast_Score=238, Evalue=8e-63,
Organism=Drosophila melanogaster, GI17737761, Length=689, Percent_Identity=25.9796806966618, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI45551938, Length=666, Percent_Identity=25.8258258258258, Blast_Score=188, Evalue=1e-47,
Organism=Drosophila melanogaster, GI45550777, Length=666, Percent_Identity=25.8258258258258, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24640050, Length=661, Percent_Identity=23.9031770045386, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24640052, Length=661, Percent_Identity=23.9031770045386, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI221474862, Length=347, Percent_Identity=28.8184438040346, Blast_Score=135, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24650487, Length=373, Percent_Identity=27.6139410187668, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24650765, Length=360, Percent_Identity=26.9444444444444, Blast_Score=119, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24650889, Length=657, Percent_Identity=23.7442922374429, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24650885, Length=306, Percent_Identity=29.7385620915033, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281362760, Length=358, Percent_Identity=24.8603351955307, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI21355943, Length=329, Percent_Identity=24.6200607902736, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24641622, Length=203, Percent_Identity=29.064039408867, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24649148, Length=357, Percent_Identity=23.249299719888, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650883, Length=290, Percent_Identity=23.1034482758621, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000718
- InterPro:   IPR018497
- InterPro:   IPR008753 [H]

Pfam domain/function: PF01431 Peptidase_M13; PF05649 Peptidase_M13_N [H]

EC number: NA

Molecular weight: Translated: 71292; Mature: 71161

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTYQDDFYQAVNGKWAETAVIPDDKPRTGGFSDLADEIEALMLDTTDAWLAGENIPDDA
CCCCHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCHHH
ILKNFVKFHRLVADYAKRDEVGVSPILPLIEEYQSLKSFSEFVANIAKYELAGLPNEFPF
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SVAPDFMNAQLNVLWAEAPSILLPDTTYYEEGNEKAEELRGIWRQSQEKLLPQFGFSTEE
CCCCHHHCCEEEEEEECCCCEECCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
IKDLLDKVIELDKQLAKYVLSREEGSEYAKLYHPYVWADFKKLAPELPLDSIFEKILGQV
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHC
PDKVIVPEERFWTEFAATYYSEANWDLLKANLIVDAANAYNAYLTDDIRVESGAYSRALS
CCCEECCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCEECCCEEECCCCHHHHCC
GTPQAMDKQKAAFYLAQGPFSQALGLWYAGQKFSPEAKADVESKVARMIEVYKSRLETAD
CCHHHHHHHHHEEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WLAPATREKAITKLNVITPHIGYPEKLPETYAKKVIDESLSLVENAQNLAKITIAHTWSK
HCCCCHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEHHH
WNKPVDRSEWHMPAHLVNAYYDPQQNQIVFPAAILQEPFYSLDQSSSANYGGIGAVIAHE
HCCCCCCCCCCCHHHHHHHHCCCCCCCEECHHHHHHCHHHHCCCCCCCCCCCHHHHHHHH
ISHAFDTNGASFDEHGSLNDWWTQEDYAAFKERTDKIVAQFDGLESHGAKVNGKLTVSEN
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCEECCEEEECCC
VADLGGVACALEAAQSEEDFSARDFFINFATIWRMKAREEYMQMLASIDVHAPGELRTNV
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
TLTNFDAFHETFDIKEGDAMWRAPKDRVIIW
EEEECHHHHHHCCCCCCCHHHCCCCCCEEEC
>Mature Secondary Structure 
TTYQDDFYQAVNGKWAETAVIPDDKPRTGGFSDLADEIEALMLDTTDAWLAGENIPDDA
CCCHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCHHH
ILKNFVKFHRLVADYAKRDEVGVSPILPLIEEYQSLKSFSEFVANIAKYELAGLPNEFPF
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SVAPDFMNAQLNVLWAEAPSILLPDTTYYEEGNEKAEELRGIWRQSQEKLLPQFGFSTEE
CCCCHHHCCEEEEEEECCCCEECCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
IKDLLDKVIELDKQLAKYVLSREEGSEYAKLYHPYVWADFKKLAPELPLDSIFEKILGQV
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHC
PDKVIVPEERFWTEFAATYYSEANWDLLKANLIVDAANAYNAYLTDDIRVESGAYSRALS
CCCEECCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCEECCCEEECCCCHHHHCC
GTPQAMDKQKAAFYLAQGPFSQALGLWYAGQKFSPEAKADVESKVARMIEVYKSRLETAD
CCHHHHHHHHHEEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WLAPATREKAITKLNVITPHIGYPEKLPETYAKKVIDESLSLVENAQNLAKITIAHTWSK
HCCCCHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEHHH
WNKPVDRSEWHMPAHLVNAYYDPQQNQIVFPAAILQEPFYSLDQSSSANYGGIGAVIAHE
HCCCCCCCCCCCHHHHHHHHCCCCCCCEECHHHHHHCHHHHCCCCCCCCCCCHHHHHHHH
ISHAFDTNGASFDEHGSLNDWWTQEDYAAFKERTDKIVAQFDGLESHGAKVNGKLTVSEN
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCEECCEEEECCC
VADLGGVACALEAAQSEEDFSARDFFINFATIWRMKAREEYMQMLASIDVHAPGELRTNV
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
TLTNFDAFHETFDIKEGDAMWRAPKDRVIIW
EEEECHHHHHHCCCCCCCHHHCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7927711 [H]