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The map label for this gene is scrA [H]

Identifier: 71911355

GI number: 71911355

Start: 1501678

End: 1503561

Strand: Reverse

Name: scrA [H]

Synonym: M5005_Spy_1542

Alternate gene names: 71911355

Gene position: 1503561-1501678 (Counterclockwise)

Preceding gene: 71911358

Following gene: 71911354

Centisome position: 81.78

GC content: 43.52

Gene sequence:

>1884_bases
ATGGATAATCGTCAGATTGCAGCTGAAGTGATTGAGGCTTTAGGTGGCCGAGAAAATGTGAGAAGTGTTGCCCACTGTGC
AACTCGCCTTCGCGTGATGGTTTATGATGAAGGAAAGATTGATAAGGAAAAAGCAGAAGCTATTGACAAGGTTAAAGGAG
CTTTCTTTAACTCTGGTCAATATCAGATGATTTTTGGAACTGGTACCGTTAATAACATTTATGACGAAGTTGTTGCTCTT
GGTTTACCCACGTCATCAACCAGTGAGCAAAAGGCAGAAGCAGGCAAACATGGCAATATCTTCCAACGGGCGATTCGTAC
GTTTGGAGATGTCTTTGTTCCCATTATTCCAGCTATTGTAGCAACGGGTCTCTTTATGGGGGTTCGTGGTTTGGTGACCC
AGCCAGCTATTATGGATTTATTTGGGGTGCATGAGTACGGGGAAAATTTTCTCATGTACACTCGTATTCTAACGGATACA
GCCTTTGTCTACTTGCCAGCTTTGGTGGCTTGGTCAGCCTTTAGGGTCTTTGGGGGTAATCCTATTATCGGTATTGTTTT
AGGATTGATGCTGGTTTCCAATGAGTTGCCTAATGCTTGGGTAGTTGCCTCTGGTGGAGATGTTAAGCCGCTAACCTTCT
TTGGATTTGTTCCTGTTGTTGGTTATCAAGGTACCGTTTTACCCGCCTTCTTTGTTGGTCTGGTAGGAGCTAAGTTGGAG
AAATGGTTGCACAAAAAGGTTCCAGAAGCTTTGGACTTATTGGTCACACCGTTTTTAACGTTTGCTATTATGAGTACCTT
GGGACTATTTGTGATTGGACCAGTTTTCCATTCTCTTGAAAACCTTGTTCTGGCTGGGACACAGGCCGTCTTGCATTTGC
CGTTTGGCATTGCAGGCTTGATTGTTGGGGGAATCCAACAATTAATCGTAGTGACTGGTATTCACCATATCTTTAACTTC
CTAGAAGCGCAGCTGATTGCCAATACCGGAAAAGATCCTTTCAATGCTTACCTAACAGCAGCAACAGCTGCTCAAGCTGG
AGCTACCTTAGCTGTTGCTGTTAAAACCAAATCAACAAAACTAAAAGGTCTGGCCTTTCCATCAACCTTGTCAGCTCTTT
TAGGGATTACTGAACCAGCTATTTTTGGGGTCAACCTCCGTTATCCAAAAGTCTTTGTTTCAGGTCTTATTGGTGGTGCC
TTAGGTGGTTGGGTCGCTGGGCTCTTTGGCATTGCAGGAACTGGTTTTGGGATTACGGTCTTACCAGGAACTCTCCTTTA
CTTGAATGGCCAATTATTACAATACCTTGTGACTATGCTTGTCGGTCTTGGGGTAGCCTTTGCAATTGCTTATACTTGGG
GTTATCAAGATAGAGAAACCCTTCCGTTACCAGCTGTCGAAGTTGATCAAACGGCTGATCAGCCAGCCTTAGCAGAGGAA
ACTTTATATAGTCCTTTGAATGGAACAGTTGTAGACTTATCTGCGGTTTCAGACCCTGTTTTTTCATCAGGTGCTATGGG
TCAAGGCTTAGCAATTAAGCCAGAAGATAATACCCTATACTCACCAGTTGATGGTAAAGTTGAAATTGTCTTTGAAACAG
GTCATGCCTATGCTATAACGTCAAGTCAAGGAGCAGAAGTGTTACTTCATATTGGTATTGATACCGTGTCGATGGCAGGA
GATGGCTTTGAATCTCTTGTAGCAGTAGGTCAGGCGGTTAAAAAAGGTGATCTTCTTGGACACTTTGATCCTAGCAAGAT
TGCAGAAGCTGGACTAGATGACACCACCATGATGATTGTGACCAATAGCGCTGACTATCAAAGCGTGGACATTCTTGCTC
AAGGACATGTTTTGATTGGTGATCAAGTGGCACTTATCAAATAA

Upstream 100 bases:

>100_bases
GTGAAGCGGATTCACTAGCGTTGGTCCTGCACATTCTTAGCCACAAAGCTGGCAGAATGGATGAGGGACTAACACCAAAT
GAAAAAGGAGACTTTTAGGC

Downstream 100 bases:

>100_bases
GGACAAAAGAGCTAACTAAGCAGCTCTTTTGTCCTGCCATGGATGGCAGGTTGGCAAAAAAATGAGAAAAGCCTAAAAAC
CTTAAATTTGTGTTATTTTA

Product: PTS system, sucrose-specific IIABC component

Products: NA

Alternate protein names: EIIBCA-Scr; EII-Scr; Sucrose-specific phosphotransferase enzyme IIB component; PTS system sucrose-specific EIIB component; Sucrose permease IIC component; PTS system sucrose-specific EIIC component; Sucrose-specific phosphotransferase enzyme IIA component; PTS system sucrose-specific EIIA component [H]

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
MDNRQIAAEVIEALGGRENVRSVAHCATRLRVMVYDEGKIDKEKAEAIDKVKGAFFNSGQYQMIFGTGTVNNIYDEVVAL
GLPTSSTSEQKAEAGKHGNIFQRAIRTFGDVFVPIIPAIVATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDT
AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVPVVGYQGTVLPAFFVGLVGAKLE
KWLHKKVPEALDLLVTPFLTFAIMSTLGLFVIGPVFHSLENLVLAGTQAVLHLPFGIAGLIVGGIQQLIVVTGIHHIFNF
LEAQLIANTGKDPFNAYLTAATAAQAGATLAVAVKTKSTKLKGLAFPSTLSALLGITEPAIFGVNLRYPKVFVSGLIGGA
LGGWVAGLFGIAGTGFGITVLPGTLLYLNGQLLQYLVTMLVGLGVAFAIAYTWGYQDRETLPLPAVEVDQTADQPALAEE
TLYSPLNGTVVDLSAVSDPVFSSGAMGQGLAIKPEDNTLYSPVDGKVEIVFETGHAYAITSSQGAEVLLHIGIDTVSMAG
DGFESLVAVGQAVKKGDLLGHFDPSKIAEAGLDDTTMMIVTNSADYQSVDILAQGHVLIGDQVALIK

Sequences:

>Translated_627_residues
MDNRQIAAEVIEALGGRENVRSVAHCATRLRVMVYDEGKIDKEKAEAIDKVKGAFFNSGQYQMIFGTGTVNNIYDEVVAL
GLPTSSTSEQKAEAGKHGNIFQRAIRTFGDVFVPIIPAIVATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDT
AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVPVVGYQGTVLPAFFVGLVGAKLE
KWLHKKVPEALDLLVTPFLTFAIMSTLGLFVIGPVFHSLENLVLAGTQAVLHLPFGIAGLIVGGIQQLIVVTGIHHIFNF
LEAQLIANTGKDPFNAYLTAATAAQAGATLAVAVKTKSTKLKGLAFPSTLSALLGITEPAIFGVNLRYPKVFVSGLIGGA
LGGWVAGLFGIAGTGFGITVLPGTLLYLNGQLLQYLVTMLVGLGVAFAIAYTWGYQDRETLPLPAVEVDQTADQPALAEE
TLYSPLNGTVVDLSAVSDPVFSSGAMGQGLAIKPEDNTLYSPVDGKVEIVFETGHAYAITSSQGAEVLLHIGIDTVSMAG
DGFESLVAVGQAVKKGDLLGHFDPSKIAEAGLDDTTMMIVTNSADYQSVDILAQGHVLIGDQVALIK
>Mature_627_residues
MDNRQIAAEVIEALGGRENVRSVAHCATRLRVMVYDEGKIDKEKAEAIDKVKGAFFNSGQYQMIFGTGTVNNIYDEVVAL
GLPTSSTSEQKAEAGKHGNIFQRAIRTFGDVFVPIIPAIVATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDT
AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVPVVGYQGTVLPAFFVGLVGAKLE
KWLHKKVPEALDLLVTPFLTFAIMSTLGLFVIGPVFHSLENLVLAGTQAVLHLPFGIAGLIVGGIQQLIVVTGIHHIFNF
LEAQLIANTGKDPFNAYLTAATAAQAGATLAVAVKTKSTKLKGLAFPSTLSALLGITEPAIFGVNLRYPKVFVSGLIGGA
LGGWVAGLFGIAGTGFGITVLPGTLLYLNGQLLQYLVTMLVGLGVAFAIAYTWGYQDRETLPLPAVEVDQTADQPALAEE
TLYSPLNGTVVDLSAVSDPVFSSGAMGQGLAIKPEDNTLYSPVDGKVEIVFETGHAYAITSSQGAEVLLHIGIDTVSMAG
DGFESLVAVGQAVKKGDLLGHFDPSKIAEAGLDDTTMMIVTNSADYQSVDILAQGHVLIGDQVALIK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790159, Length=627, Percent_Identity=29.9840510366826, Blast_Score=258, Evalue=6e-70,
Organism=Escherichia coli, GI2367362, Length=427, Percent_Identity=31.1475409836066, Blast_Score=208, Evalue=8e-55,
Organism=Escherichia coli, GI48994906, Length=487, Percent_Identity=28.1314168377823, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1788769, Length=439, Percent_Identity=27.3348519362187, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1786894, Length=146, Percent_Identity=35.6164383561644, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1788757, Length=140, Percent_Identity=37.1428571428571, Blast_Score=102, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR010973 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 66280; Mature: 66280

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNRQIAAEVIEALGGRENVRSVAHCATRLRVMVYDEGKIDKEKAEAIDKVKGAFFNSGQ
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHCCCCC
YQMIFGTGTVNNIYDEVVALGLPTSSTSEQKAEAGKHGNIFQRAIRTFGDVFVPIIPAIV
EEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
ATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDTAFVYLPALVAWSAFRVFGGN
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVPVVGYQGTVLPAFFVGLVGAKLE
CHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEHCCHHHHCCCCCCHHHHHHHHHHHHHHH
KWLHKKVPEALDLLVTPFLTFAIMSTLGLFVIGPVFHSLENLVLAGTQAVLHLPFGIAGL
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCHHHHHH
IVGGIQQLIVVTGIHHIFNFLEAQLIANTGKDPFNAYLTAATAAQAGATLAVAVKTKSTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCC
LKGLAFPSTLSALLGITEPAIFGVNLRYPKVFVSGLIGGALGGWVAGLFGIAGTGFGITV
CCCCCCHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
LPGTLLYLNGQLLQYLVTMLVGLGVAFAIAYTWGYQDRETLPLPAVEVDQTADQPALAEE
CCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCHHHH
TLYSPLNGTVVDLSAVSDPVFSSGAMGQGLAIKPEDNTLYSPVDGKVEIVFETGHAYAIT
HHCCCCCCCEEEECCCCCCCCCCCCCCCCEEECCCCCCEECCCCCEEEEEEECCCEEEEE
SSQGAEVLLHIGIDTVSMAGDGFESLVAVGQAVKKGDLLGHFDPSKIAEAGLDDTTMMIV
CCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCEEEEE
TNSADYQSVDILAQGHVLIGDQVALIK
ECCCCCCEEEEEECCCEEECCCEEECC
>Mature Secondary Structure
MDNRQIAAEVIEALGGRENVRSVAHCATRLRVMVYDEGKIDKEKAEAIDKVKGAFFNSGQ
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHCCCCC
YQMIFGTGTVNNIYDEVVALGLPTSSTSEQKAEAGKHGNIFQRAIRTFGDVFVPIIPAIV
EEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
ATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDTAFVYLPALVAWSAFRVFGGN
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVPVVGYQGTVLPAFFVGLVGAKLE
CHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEHCCHHHHCCCCCCHHHHHHHHHHHHHHH
KWLHKKVPEALDLLVTPFLTFAIMSTLGLFVIGPVFHSLENLVLAGTQAVLHLPFGIAGL
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCHHHHHH
IVGGIQQLIVVTGIHHIFNFLEAQLIANTGKDPFNAYLTAATAAQAGATLAVAVKTKSTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCC
LKGLAFPSTLSALLGITEPAIFGVNLRYPKVFVSGLIGGALGGWVAGLFGIAGTGFGITV
CCCCCCHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
LPGTLLYLNGQLLQYLVTMLVGLGVAFAIAYTWGYQDRETLPLPAVEVDQTADQPALAEE
CCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCHHHH
TLYSPLNGTVVDLSAVSDPVFSSGAMGQGLAIKPEDNTLYSPVDGKVEIVFETGHAYAIT
HHCCCCCCCEEEECCCCCCCCCCCCCCCCEEECCCCCCEECCCCCEEEEEEECCCEEEEE
SSQGAEVLLHIGIDTVSMAGDGFESLVAVGQAVKKGDLLGHFDPSKIAEAGLDDTTMMIV
CCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCEEEEE
TNSADYQSVDILAQGHVLIGDQVALIK
ECCCCCCEEEEEECCCEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2536656; 12397186; 8336109 [H]