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The map label for this gene is pyrR [H]

Identifier: 71910452

GI number: 71910452

Start: 641379

End: 641900

Strand: Direct

Name: pyrR [H]

Synonym: M5005_Spy_0639

Alternate gene names: 71910452

Gene position: 641379-641900 (Clockwise)

Preceding gene: 71910451

Following gene: 71910453

Centisome position: 34.88

GC content: 41.76

Gene sequence:

>522_bases
ATGAAAACTAAGGAAATTGTTGATGACGTGACCATGAAACGCGCCATTACCCGTATTACTTATGAAATTATTGAACGTAA
TAAACAATTAGACAATGTGGTTTTGGCAGGCATCAAAACGAGAGGTGTTTTTCTAGCTCGTCGCATTCAAGAAAGACTGC
ATCAATTAGAAGGGTTGGATTTACCAATTGGTGAGTTAGACATCAAGCCTTTTAGAGATGACATGAGAGTTGAGGAAGAC
ACAACTCTGATGTCAGTAGATATTACAGGCAAGGATGTGATTTTGATTGATGATGTGCTTTATACTGGTCGTACCATCCG
CGCAGCCATCGATAACTTAGTGAGTTTAGGTCGACCAGCCCGTGTTAGTCTAGCTGTTTTGGTGGATCGTGGCCATCGGG
AATTACCGATTCGCGCGGATTACGTTGGGAAAAATATTCCAACAAGCAGTGTAGAAGAAATTGTTGTTGAGGTTGTCGAA
GTCGATGGCCGTGATCGTGTTAGCATTATTGACCCAACATAA

Upstream 100 bases:

>100_bases
TTAAAAACATGCATCATGATACTTAATTGTGCTATATTTTGCTGAATCTCCTTGTTTCCAAGGAGATCTTTTTATTTGAA
TTTTTAGAGGAGGTTTCAAC

Downstream 100 bases:

>100_bases
GAAAGAGGTTTTACTGTGAAAGATGTCATTTATGATGTGGAAGAAGTGCCAAAGGCAGGTATGTTAGTTGGTTTGTCCTT
TCAGCACTTATTTGCTATGT

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MKTKEIVDDVTMKRAITRITYEIIERNKQLDNVVLAGIKTRGVFLARRIQERLHQLEGLDLPIGELDIKPFRDDMRVEED
TTLMSVDITGKDVILIDDVLYTGRTIRAAIDNLVSLGRPARVSLAVLVDRGHRELPIRADYVGKNIPTSSVEEIVVEVVE
VDGRDRVSIIDPT

Sequences:

>Translated_173_residues
MKTKEIVDDVTMKRAITRITYEIIERNKQLDNVVLAGIKTRGVFLARRIQERLHQLEGLDLPIGELDIKPFRDDMRVEED
TTLMSVDITGKDVILIDDVLYTGRTIRAAIDNLVSLGRPARVSLAVLVDRGHRELPIRADYVGKNIPTSSVEEIVVEVVE
VDGRDRVSIIDPT
>Mature_173_residues
MKTKEIVDDVTMKRAITRITYEIIERNKQLDNVVLAGIKTRGVFLARRIQERLHQLEGLDLPIGELDIKPFRDDMRVEED
TTLMSVDITGKDVILIDDVLYTGRTIRAAIDNLVSLGRPARVSLAVLVDRGHRELPIRADYVGKNIPTSSVEEIVVEVVE
VDGRDRVSIIDPT

Specific function: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 19529; Mature: 19529

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKEIVDDVTMKRAITRITYEIIERNKQLDNVVLAGIKTRGVFLARRIQERLHQLEGLD
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEECCCHHHHHHHHHHHHHHHHHCCCC
LPIGELDIKPFRDDMRVEEDTTLMSVDITGKDVILIDDVLYTGRTIRAAIDNLVSLGRPA
CCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEECHHHCCCHHHHHHHHHHHCCCCC
RVSLAVLVDRGHRELPIRADYVGKNIPTSSVEEIVVEVVEVDGRDRVSIIDPT
CEEEEEEEECCCCCCCEEHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCC
>Mature Secondary Structure
MKTKEIVDDVTMKRAITRITYEIIERNKQLDNVVLAGIKTRGVFLARRIQERLHQLEGLD
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEECCCHHHHHHHHHHHHHHHHHCCCC
LPIGELDIKPFRDDMRVEEDTTLMSVDITGKDVILIDDVLYTGRTIRAAIDNLVSLGRPA
CCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEECHHHCCCHHHHHHHHHHHCCCCC
RVSLAVLVDRGHRELPIRADYVGKNIPTSSVEEIVVEVVEVDGRDRVSIIDPT
CEEEEEEEECCCCCCCEEHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]