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The map label for this gene is yecS [H]

Identifier: 71910050

GI number: 71910050

Start: 242418

End: 243986

Strand: Reverse

Name: yecS [H]

Synonym: M5005_Spy_0236

Alternate gene names: 71910050

Gene position: 243986-242418 (Counterclockwise)

Preceding gene: 71910061

Following gene: 71910049

Centisome position: 13.27

GC content: 42.45

Gene sequence:

>1569_bases
ATGAAAAAGCTAATCCTTAGCTGTTTGGTCGCCTTGGCCCTTCTGTTTGGAGGAATGAGCCGGGCTCAAGCAAACCAATA
TTTAAGAGTCGGAATGGAAGCAGCCTATGCTCCTTTTAACTGGACTCAAGATGACGCTTCAAACGGGGCTGTTCCAATTG
AAGGAACTAGCCAATACGCCAACGGTTACGATGTCCAAGTCGCTAAAAAAGTCGCTAAAGCTATGAACAAAGAACTTTTA
GTCGTTAAGACCTCTTGGACCGGTTTAATTCCAGCATTAACTTCTGGAAAAATCGATATGATCGCTGCTGGTATGAGTCC
TACCAAAGAGCGTAGAAACGAAATTAGCTTCTCAAACAGCTACTACACTAGCCAACCTGTTCTAGTCGTAACTGCCAATG
GCAAATATGCTGATGCAACAAGCCTCAAGGATTTTTCTGGAGCTAAAGTAACTGCCCAGCAAGGCGTTTGGCATGTCAAT
CTCTTAACTCAACTAAAAGGTGCTAAGTTACAAACACCAATGGGAGATTTCTCTCAAATGCGACAAGCCCTTACTTCGGG
TGTTATCGATGCCTATATTTCTGAACGACCTGAAGCCATGACTGCTGAAGCTGCTGATAGCCGTTTGAAAATGATCACTC
TTAAAAAAGGGTTTGCTGTTGCTGAATCAGATGCTGCTATCGCTGTCGGAATGAAAAAAAATGACGATCGTATGGCAACT
GTCAACCAAGTGCTTGAAGGATTTTCTCAAACAGATCGTATGGCCCTGATGGATGATATGGTTACCAAACAACCCGTGGA
AAAGAAAGCCGAAGATGCTAAAGCATCATTTCTAGGCCAAATGTGGGCTATTTTTAAAGGTAACTGGAAGCAATTCTTAC
GTGGAACTGGAATGACCCTTCTGATTTCCATGGTCGGAACCATTACAGGTCTCTTTATTGGATTATTAATCGGTATTTTC
CGTACAGCTCCTAAAGCTAAGCATAAAGTAGCTGCCTTGGGACAAAAACTCTTTGGTTGGTTACTCACTATTTATATCGA
AATCTTCCGTGGGACACCTATGATTGTTCAATCTATGGTTATCTACTACGGAACAGCGCAAGCCTTTGGTATTTCGATCG
ACCGTACCCTAGCGGCTATTTTTATCGTATCTATCAATACGGGTGCCTATATGAGTGAAATTGTTCGCGGTGGTATTTTC
GCTGTCGACAAAGGTCAATTCGAAGCAGCAACTGCTCTTGGCTTTACTCACGGACAAACCATGCGTAAAATCGTGCTACC
ACAAGTTGTTCGCAACATTTTACCAGCAACAGGTAATGAGTTTGTCATCAATATCAAAGATACTTCTGTCTTGAATGTTA
TCTCTGTTGTGGAACTTTACTTCTCAGGTAATACCGTAGCCACACAAACCTACCAATATTTCCAAACCTTTACGATTATC
GCCATTATCTACTTTGTTCTTACCTTCACGGTGACACGTATCCTTCGTTATATTGAACGCCGTTTCGATGCCGATACTTA
CACCACTGGAGCAAACCAAATGCAGATTGCGGAGGTCTCAAATGTCTAA

Upstream 100 bases:

>100_bases
ATTTTTCCATATTTCAACCTATTCACTGATAATATATTGAAATAGGATGCAAATTGCTGTAAAATAGGTCTGAATACTAT
TTTTGAAACAGGAGACCTAT

Downstream 100 bases:

>100_bases
CTCAATTATTGAAATCAAAAATCTCAAAAAATCTTACGGCAGCAATGAAGTACTCAAAGATATCTCCCTTTCTGTTAACA
AGGGAGAAGTGATTTCCATT

Product: amino acid ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MKKLILSCLVALALLFGGMSRAQANQYLRVGMEAAYAPFNWTQDDASNGAVPIEGTSQYANGYDVQVAKKVAKAMNKELL
VVKTSWTGLIPALTSGKIDMIAAGMSPTKERRNEISFSNSYYTSQPVLVVTANGKYADATSLKDFSGAKVTAQQGVWHVN
LLTQLKGAKLQTPMGDFSQMRQALTSGVIDAYISERPEAMTAEAADSRLKMITLKKGFAVAESDAAIAVGMKKNDDRMAT
VNQVLEGFSQTDRMALMDDMVTKQPVEKKAEDAKASFLGQMWAIFKGNWKQFLRGTGMTLLISMVGTITGLFIGLLIGIF
RTAPKAKHKVAALGQKLFGWLLTIYIEIFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIFIVSINTGAYMSEIVRGGIF
AVDKGQFEAATALGFTHGQTMRKIVLPQVVRNILPATGNEFVINIKDTSVLNVISVVELYFSGNTVATQTYQYFQTFTII
AIIYFVLTFTVTRILRYIERRFDADTYTTGANQMQIAEVSNV

Sequences:

>Translated_522_residues
MKKLILSCLVALALLFGGMSRAQANQYLRVGMEAAYAPFNWTQDDASNGAVPIEGTSQYANGYDVQVAKKVAKAMNKELL
VVKTSWTGLIPALTSGKIDMIAAGMSPTKERRNEISFSNSYYTSQPVLVVTANGKYADATSLKDFSGAKVTAQQGVWHVN
LLTQLKGAKLQTPMGDFSQMRQALTSGVIDAYISERPEAMTAEAADSRLKMITLKKGFAVAESDAAIAVGMKKNDDRMAT
VNQVLEGFSQTDRMALMDDMVTKQPVEKKAEDAKASFLGQMWAIFKGNWKQFLRGTGMTLLISMVGTITGLFIGLLIGIF
RTAPKAKHKVAALGQKLFGWLLTIYIEIFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIFIVSINTGAYMSEIVRGGIF
AVDKGQFEAATALGFTHGQTMRKIVLPQVVRNILPATGNEFVINIKDTSVLNVISVVELYFSGNTVATQTYQYFQTFTII
AIIYFVLTFTVTRILRYIERRFDADTYTTGANQMQIAEVSNV
>Mature_522_residues
MKKLILSCLVALALLFGGMSRAQANQYLRVGMEAAYAPFNWTQDDASNGAVPIEGTSQYANGYDVQVAKKVAKAMNKELL
VVKTSWTGLIPALTSGKIDMIAAGMSPTKERRNEISFSNSYYTSQPVLVVTANGKYADATSLKDFSGAKVTAQQGVWHVN
LLTQLKGAKLQTPMGDFSQMRQALTSGVIDAYISERPEAMTAEAADSRLKMITLKKGFAVAESDAAIAVGMKKNDDRMAT
VNQVLEGFSQTDRMALMDDMVTKQPVEKKAEDAKASFLGQMWAIFKGNWKQFLRGTGMTLLISMVGTITGLFIGLLIGIF
RTAPKAKHKVAALGQKLFGWLLTIYIEIFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIFIVSINTGAYMSEIVRGGIF
AVDKGQFEAATALGFTHGQTMRKIVLPQVVRNILPATGNEFVINIKDTSVLNVISVVELYFSGNTVATQTYQYFQTFTII
AIIYFVLTFTVTRILRYIERRFDADTYTTGANQMQIAEVSNV

Specific function: Probably part of the binding-protein-dependent transport system yecCS for an amino acid; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=212, Percent_Identity=35.8490566037736, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1787030, Length=211, Percent_Identity=38.3886255924171, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1788646, Length=179, Percent_Identity=31.8435754189944, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1787087, Length=228, Percent_Identity=28.5087719298246, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI87082239, Length=217, Percent_Identity=30.4147465437788, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786873, Length=228, Percent_Identity=26.3157894736842, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1788645, Length=235, Percent_Identity=28.936170212766, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787086, Length=221, Percent_Identity=28.0542986425339, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786874, Length=246, Percent_Identity=23.9837398373984, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787031, Length=202, Percent_Identity=30.1980198019802, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1787088, Length=190, Percent_Identity=28.4210526315789, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI48994930, Length=135, Percent_Identity=31.8518518518519, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1787085, Length=158, Percent_Identity=28.4810126582279, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788648, Length=169, Percent_Identity=28.4023668639053, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788228, Length=230, Percent_Identity=24.7826086956522, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 57171; Mature: 57171

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLILSCLVALALLFGGMSRAQANQYLRVGMEAAYAPFNWTQDDASNGAVPIEGTSQYA
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCHHHC
NGYDVQVAKKVAKAMNKELLVVKTSWTGLIPALTSGKIDMIAAGMSPTKERRNEISFSNS
CCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHCCCCEEEEEECCCCCHHHHHCCCCCCC
YYTSQPVLVVTANGKYADATSLKDFSGAKVTAQQGVWHVNLLTQLKGAKLQTPMGDFSQM
EECCCCEEEEECCCCCCCCCCCCCCCCCEEEHHCCCEEEEHHHHCCCCCCCCCCCHHHHH
RQALTSGVIDAYISERPEAMTAEAADSRLKMITLKKGFAVAESDAAIAVGMKKNDDRMAT
HHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEECCCEEECCCCEEEEECCCCCCHHHH
VNQVLEGFSQTDRMALMDDMVTKQPVEKKAEDAKASFLGQMWAIFKGNWKQFLRGTGMTL
HHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHH
LISMVGTITGLFIGLLIGIFRTAPKAKHKVAALGQKLFGWLLTIYIEIFRGTPMIVQSMV
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
IYYGTAQAFGISIDRTLAAIFIVSINTGAYMSEIVRGGIFAVDKGQFEAATALGFTHGQT
HHCCCHHHHCCCHHHHEEEEEEEEECCCHHHHHHHCCCEEEEECCCCHHHHHHCCCCCHH
MRKIVLPQVVRNILPATGNEFVINIKDTSVLNVISVVELYFSGNTVATQTYQYFQTFTII
HHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHH
AIIYFVLTFTVTRILRYIERRFDADTYTTGANQMQIAEVSNV
HHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEECCCC
>Mature Secondary Structure
MKKLILSCLVALALLFGGMSRAQANQYLRVGMEAAYAPFNWTQDDASNGAVPIEGTSQYA
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCHHHC
NGYDVQVAKKVAKAMNKELLVVKTSWTGLIPALTSGKIDMIAAGMSPTKERRNEISFSNS
CCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHCCCCEEEEEECCCCCHHHHHCCCCCCC
YYTSQPVLVVTANGKYADATSLKDFSGAKVTAQQGVWHVNLLTQLKGAKLQTPMGDFSQM
EECCCCEEEEECCCCCCCCCCCCCCCCCEEEHHCCCEEEEHHHHCCCCCCCCCCCHHHHH
RQALTSGVIDAYISERPEAMTAEAADSRLKMITLKKGFAVAESDAAIAVGMKKNDDRMAT
HHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEECCCEEECCCCEEEEECCCCCCHHHH
VNQVLEGFSQTDRMALMDDMVTKQPVEKKAEDAKASFLGQMWAIFKGNWKQFLRGTGMTL
HHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHH
LISMVGTITGLFIGLLIGIFRTAPKAKHKVAALGQKLFGWLLTIYIEIFRGTPMIVQSMV
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
IYYGTAQAFGISIDRTLAAIFIVSINTGAYMSEIVRGGIFAVDKGQFEAATALGFTHGQT
HHCCCHHHHCCCHHHHEEEEEEEEECCCHHHHHHHCCCEEEEECCCCHHHHHHCCCCCHH
MRKIVLPQVVRNILPATGNEFVINIKDTSVLNVISVVELYFSGNTVATQTYQYFQTFTII
HHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHH
AIIYFVLTFTVTRILRYIERRFDADTYTTGANQMQIAEVSNV
HHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]