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The map label for this gene is lpxD

Identifier: 71892063

GI number: 71892063

Start: 335909

End: 336940

Strand: Direct

Name: lpxD

Synonym: BPEN_289

Alternate gene names: 71892063

Gene position: 335909-336940 (Clockwise)

Preceding gene: 71892062

Following gene: 71892064

Centisome position: 42.43

GC content: 34.69

Gene sequence:

>1032_bases
ATGATCGAAATGCGATTATCTGATCTAGCACAACAGTTAAATGCTAAATTACATGGAGATGAAAATATTATTATTACTGG
TGTTGCTTCTATAAATAACGCACAAGTAGGACATATTACTTTTTTAAAAGATCAGCGATTTCTAAGTCAACTAAGCTCCT
GTCGAGCCTCAGCAGTCATATTGTCTAAAAACAACTTAATTTTTTGTAAGATTGCTGCATTAGTAGTAGAAGATCCTTAT
ATTGCGTATGTTAAAATAGCACGATTGATGGATACTACCCCTAAACCATCAAAAAACATTGCATCTGGAGCTATAATTGC
TTCAGATGCAATTTTAGGTCAAAGAGTAGGGATTGGCGCTAATGCAGTTATAGAATCTGAAGTAATTTTAGGTGATGATG
TAATCATTGGTCCCGGTAGTTTCGTAGGAAAAAAAACAAGAATAGGAACAGGTACACGTTTATGGGCTAATGTTACTATA
TATCATGAAGTAGAAATTGGTGAATGCTGCTTAATACAATCTGGAGCTATAATTGGTTCTGATGGATTTGGGTATATTAA
TGACCATGGTGTGTGGATTAAAATTCCTCATTTAGGAACAGTAAAAATTGGAAATAATGTGGAAATAGGTGCTTGTACTA
CTATTGACCGTGGAACATTAGATGATACTAAAATTGAAAACGGAGTAATTATTGATAATCAGTGCCAAATTGCACATAAT
GTCATAATAGGCGCGCGCACTGCAATAGCAGGGGGTGTCATTATGGCTGGGAGTTTAACAATCGGAAGAGATTGCATGAT
AGGCGGAGCTAGTGTAATTAATGGGCACATAAATATTTGTGATAAAGTCACGATAACCGGAATGGGTATGGTAATAAAAG
CAATAACACAACCTGGTATTTACTCATCAGGTATTCCTGTCCAACTAAACACAGTATGGTGGAAAACTGCCGCGTTAATT
ATGCGGATTAGTAATATGAATAAACGTATAAAAACTATAGAAGAAAAATTAAAAAAACTATTGTTCCTATAA

Upstream 100 bases:

>100_bases
AGAAAATTACGATATAGTAATCGACACTAATGCTGTACTGTATCACAGTATTCGTGTTACGGATATTACCAATTCTGTAA
TGAAACAAGTTGGATAAGTT

Downstream 100 bases:

>100_bases
ATTTTAAGATAATTAGGACAGCTTATTCTTCATCTTGTTAGAATGAACGGGATAGTATTGTTAATACGATTTATTACCTT
TAGACAGGAATAGAAAACCT

Product: UDP-3-O-(3-hydroxymyristoyl)-glucosamine N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MIEMRLSDLAQQLNAKLHGDENIIITGVASINNAQVGHITFLKDQRFLSQLSSCRASAVILSKNNLIFCKIAALVVEDPY
IAYVKIARLMDTTPKPSKNIASGAIIASDAILGQRVGIGANAVIESEVILGDDVIIGPGSFVGKKTRIGTGTRLWANVTI
YHEVEIGECCLIQSGAIIGSDGFGYINDHGVWIKIPHLGTVKIGNNVEIGACTTIDRGTLDDTKIENGVIIDNQCQIAHN
VIIGARTAIAGGVIMAGSLTIGRDCMIGGASVINGHINICDKVTITGMGMVIKAITQPGIYSSGIPVQLNTVWWKTAALI
MRISNMNKRIKTIEEKLKKLLFL

Sequences:

>Translated_343_residues
MIEMRLSDLAQQLNAKLHGDENIIITGVASINNAQVGHITFLKDQRFLSQLSSCRASAVILSKNNLIFCKIAALVVEDPY
IAYVKIARLMDTTPKPSKNIASGAIIASDAILGQRVGIGANAVIESEVILGDDVIIGPGSFVGKKTRIGTGTRLWANVTI
YHEVEIGECCLIQSGAIIGSDGFGYINDHGVWIKIPHLGTVKIGNNVEIGACTTIDRGTLDDTKIENGVIIDNQCQIAHN
VIIGARTAIAGGVIMAGSLTIGRDCMIGGASVINGHINICDKVTITGMGMVIKAITQPGIYSSGIPVQLNTVWWKTAALI
MRISNMNKRIKTIEEKLKKLLFL
>Mature_343_residues
MIEMRLSDLAQQLNAKLHGDENIIITGVASINNAQVGHITFLKDQRFLSQLSSCRASAVILSKNNLIFCKIAALVVEDPY
IAYVKIARLMDTTPKPSKNIASGAIIASDAILGQRVGIGANAVIESEVILGDDVIIGPGSFVGKKTRIGTGTRLWANVTI
YHEVEIGECCLIQSGAIIGSDGFGYINDHGVWIKIPHLGTVKIGNNVEIGACTTIDRGTLDDTKIENGVIIDNQCQIAHN
VIIGARTAIAGGVIMAGSLTIGRDCMIGGASVINGHINICDKVTITGMGMVIKAITQPGIYSSGIPVQLNTVWWKTAALI
MRISNMNKRIKTIEEKLKKLLFL

Specific function: Lipid A biosynthesis; third step. [C]

COG id: COG1044

COG function: function code M; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxD subfamily

Homologues:

Organism=Escherichia coli, GI1786376, Length=339, Percent_Identity=65.1917404129793, Blast_Score=469, Evalue=1e-134,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LPXD_BLOPB (Q493C2)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277793.1
- ProteinModelPortal:   Q493C2
- SMR:   Q493C2
- STRING:   Q493C2
- GeneID:   3562598
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_289
- eggNOG:   COG1044
- HOGENOM:   HBG469615
- OMA:   WFREIIA
- BioCyc:   CBLO291272:BPEN_289-MONOMER
- HAMAP:   MF_00523
- InterPro:   IPR018357
- InterPro:   IPR011004
- InterPro:   IPR007691
- InterPro:   IPR020573
- TIGRFAMs:   TIGR01853

Pfam domain/function: PF04613 LpxD; SSF51161 Trimer_LpxA_like

EC number: 2.3.1.-

Molecular weight: Translated: 36655; Mature: 36655

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEMRLSDLAQQLNAKLHGDENIIITGVASINNAQVGHITFLKDQRFLSQLSSCRASAVI
CEEECHHHHHHHHCCEECCCCCEEEEEEEECCCCEEEEEEEEECHHHHHHHHCCCEEEEE
LSKNNLIFCKIAALVVEDPYIAYVKIARLMDTTPKPSKNIASGAIIASDAILGQRVGIGA
EECCCEEEEEEEEEEECCCCEEEHHHHHHHCCCCCCCCCCCCCEEEECCCHHCCCCCCCC
NAVIESEVILGDDVIIGPGSFVGKKTRIGTGTRLWANVTIYHEVEIGECCLIQSGAIIGS
CEEEECEEEECCCEEECCCCCCCCEEECCCCCEEEEEEEEEEEEECCCEEEEECCCEECC
DGFGYINDHGVWIKIPHLGTVKIGNNVEIGACTTIDRGTLDDTKIENGVIIDNQCQIAHN
CCCCEEECCEEEEEECCCEEEEECCCEEEEEEEECCCCCCCCCCCCCCEEECCCCEEEEE
VIIGARTAIAGGVIMAGSLTIGRDCMIGGASVINGHINICDKVTITGMGMVIKAITQPGI
EEEECHHHHCCCEEEECCEEECCEEEECCCEEEECCEEEEEEEEEECHHHEEHHHCCCCC
YSSGIPVQLNTVWWKTAALIMRISNMNKRIKTIEEKLKKLLFL
CCCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIEMRLSDLAQQLNAKLHGDENIIITGVASINNAQVGHITFLKDQRFLSQLSSCRASAVI
CEEECHHHHHHHHCCEECCCCCEEEEEEEECCCCEEEEEEEEECHHHHHHHHCCCEEEEE
LSKNNLIFCKIAALVVEDPYIAYVKIARLMDTTPKPSKNIASGAIIASDAILGQRVGIGA
EECCCEEEEEEEEEEECCCCEEEHHHHHHHCCCCCCCCCCCCCEEEECCCHHCCCCCCCC
NAVIESEVILGDDVIIGPGSFVGKKTRIGTGTRLWANVTIYHEVEIGECCLIQSGAIIGS
CEEEECEEEECCCEEECCCCCCCCEEECCCCCEEEEEEEEEEEEECCCEEEEECCCEECC
DGFGYINDHGVWIKIPHLGTVKIGNNVEIGACTTIDRGTLDDTKIENGVIIDNQCQIAHN
CCCCEEECCEEEEEECCCEEEEECCCEEEEEEEECCCCCCCCCCCCCCEEECCCCEEEEE
VIIGARTAIAGGVIMAGSLTIGRDCMIGGASVINGHINICDKVTITGMGMVIKAITQPGI
EEEECHHHHCCCEEEECCEEECCEEEECCCEEEECCEEEEEEEEEECHHHEEHHHCCCCC
YSSGIPVQLNTVWWKTAALIMRISNMNKRIKTIEEKLKKLLFL
CCCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA