| Definition | Candidatus Blochmannia pennsylvanicus str. BPEN, complete genome. |
|---|---|
| Accession | NC_007292 |
| Length | 791,654 |
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The map label for this gene is ftsI [H]
Identifier: 71891923
GI number: 71891923
Start: 170769
End: 172463
Strand: Direct
Name: ftsI [H]
Synonym: BPEN_140
Alternate gene names: 71891923
Gene position: 170769-172463 (Clockwise)
Preceding gene: 71891922
Following gene: 71891924
Centisome position: 21.57
GC content: 34.1
Gene sequence:
>1695_bases ATGAAGTTTGAACCTTACAATTTTAAAATAATTTTAAATAACAAACGTTTTAATTTATTGTATAGCGGTATTTTTTTTGT ATTAATTATTTTGCTATTGAGATTAGCTTTTTTGCAGATTATTTATTCTGACCAGCTAATTAATGAAGGTAACATGCGTT CGTTACGCGTGCAAAGCACACTCTCTACTCGGGGTATTATTACTGATAGAATGGGTCAACTATTGGCAATTAGTATACCG GCTGATTCGGTTTGGATTGATCCTCAAGAAATTAGCAAGAGTGGCGGTATTACTGCTGATATACGTCGTTGGACAGAATT ATCTGAGGTATTATCTATATCATCAGATAAACTATCATCTCTCATCAATAATCATACTACAGATCATTTTTTGTATTTAG CACGACAGATTGATCCTACTATTTCTAAATACATTAGTCAACTTAAATTACCAGGAGTATATTTGCAACAAGGATCAAAA AGATATTACCCTGCTGGGTGTGCAACTGCACATTTGATAGGAGTAACAGATGTAGATAGCCAAGGGATTGAAGGTATAGA AAAAAGTTTTGATTCTTGGTTGACTGGTCAACCCAAAACAAGAGTAATACGCAAAGATAGATTTGGTCGAACAATTGAAG AAATTACTTTGAATAACGGTCAATCTTCTCAGAATATTATTCTCAGTATCGACGAACGCCTGCAAGATTTAGCATACCGT GAATTAAATAATGCTGTACATATGAATAAAGCAGAATCCGGTAGTATAGTATTGATAGATATCAATACTGGAGAAATTCT AGCTATGACAAACAGTCCATCATATAATCCAAACAATTTTTTGTCCATTGTTAATAAATCTGTTATGCGTAACCGTGCTA TTACTGATGCATTTGAACCAGGTTCTACCGTGAAACCTATTGTGATTATGGCTGCATTAAAACATAAGATAATCACAAAA GACACTATTATGAATACATCACCCTATATACTTAATGGGCATCAAATTAAGGATGTACTATATCGTAGAAAATTGACTAT TAGAGAAATATTACAAAAGTCTAGTAATGTTGGTGTTTCTAAATTAGCATTAGCTATGCCTGCAGCAGTTTTAGTCAATA CATATTCAAATTTTGGAATGGGTAAATCAACAAATATAGGCTTAGTGGGAGAAAGTAACGGGATATATCCATATAATAGA TGTTGGTCAGACATAGAACGCGCCACCTTTTCTTATGGATATGGTTTGATGATTACTCCGTTACAATTAGCTAAAGTTTA TGCTACTATTGGTGGAATGGGAATATCTCGACCACTTTCTATTATACGAGTTGATTCTTCCTCGGTATTAGGAAATCAAG TTTTTCCAAGATCTTTAGTGCGAACTGTTTTAGACATGATGGAAAATGTGTCATTGCCGAGTGGTGGTTGTCAATCTGCA ATTAAAGGATATAGGGTTGCTGTAAAAACTGGGACTGTTAAGATAGTTGGATCACATGGGAAATATATTAATAAGTATAT TGCATGTACTGCTGGAGTAGCTCCAGCGAGTAATCCCAGATTTGCTTTAGCAGTAGTAATAAATGATCCTAAAAATGGTC ATTATTATGGAAGTATGGTATCAGCGCCAGTTTTTAGCGCAGTGATGGGCAATGCATTAAAAATCATGAATGTAGTGCCA GATTTTTTGCAGTAA
Upstream 100 bases:
>100_bases TAATACATTGTACTAATCTATAAAATTTATTTATGTGATAAATAAAAATATTATTTGAAAATAGTTATAGCTCCTCCTGT GATGATACAATTTATGTTAT
Downstream 100 bases:
>100_bases TTTTATAAGCAATCAGGTCTCTTTGAGAAAATTATATGTATGATTCACGTAATTTATATAAATTATTTATTCCATATGTT TTTAATAATCCTACTAGTCC
Product: division-specific transpeptidase
Products: NA
Alternate protein names: Penicillin-binding protein 3; PBP-3; Peptidoglycan glycosyltransferase 3 [H]
Number of amino acids: Translated: 564; Mature: 564
Protein sequence:
>564_residues MKFEPYNFKIILNNKRFNLLYSGIFFVLIILLLRLAFLQIIYSDQLINEGNMRSLRVQSTLSTRGIITDRMGQLLAISIP ADSVWIDPQEISKSGGITADIRRWTELSEVLSISSDKLSSLINNHTTDHFLYLARQIDPTISKYISQLKLPGVYLQQGSK RYYPAGCATAHLIGVTDVDSQGIEGIEKSFDSWLTGQPKTRVIRKDRFGRTIEEITLNNGQSSQNIILSIDERLQDLAYR ELNNAVHMNKAESGSIVLIDINTGEILAMTNSPSYNPNNFLSIVNKSVMRNRAITDAFEPGSTVKPIVIMAALKHKIITK DTIMNTSPYILNGHQIKDVLYRRKLTIREILQKSSNVGVSKLALAMPAAVLVNTYSNFGMGKSTNIGLVGESNGIYPYNR CWSDIERATFSYGYGLMITPLQLAKVYATIGGMGISRPLSIIRVDSSSVLGNQVFPRSLVRTVLDMMENVSLPSGGCQSA IKGYRVAVKTGTVKIVGSHGKYINKYIACTAGVAPASNPRFALAVVINDPKNGHYYGSMVSAPVFSAVMGNALKIMNVVP DFLQ
Sequences:
>Translated_564_residues MKFEPYNFKIILNNKRFNLLYSGIFFVLIILLLRLAFLQIIYSDQLINEGNMRSLRVQSTLSTRGIITDRMGQLLAISIP ADSVWIDPQEISKSGGITADIRRWTELSEVLSISSDKLSSLINNHTTDHFLYLARQIDPTISKYISQLKLPGVYLQQGSK RYYPAGCATAHLIGVTDVDSQGIEGIEKSFDSWLTGQPKTRVIRKDRFGRTIEEITLNNGQSSQNIILSIDERLQDLAYR ELNNAVHMNKAESGSIVLIDINTGEILAMTNSPSYNPNNFLSIVNKSVMRNRAITDAFEPGSTVKPIVIMAALKHKIITK DTIMNTSPYILNGHQIKDVLYRRKLTIREILQKSSNVGVSKLALAMPAAVLVNTYSNFGMGKSTNIGLVGESNGIYPYNR CWSDIERATFSYGYGLMITPLQLAKVYATIGGMGISRPLSIIRVDSSSVLGNQVFPRSLVRTVLDMMENVSLPSGGCQSA IKGYRVAVKTGTVKIVGSHGKYINKYIACTAGVAPASNPRFALAVVINDPKNGHYYGSMVSAPVFSAVMGNALKIMNVVP DFLQ >Mature_564_residues MKFEPYNFKIILNNKRFNLLYSGIFFVLIILLLRLAFLQIIYSDQLINEGNMRSLRVQSTLSTRGIITDRMGQLLAISIP ADSVWIDPQEISKSGGITADIRRWTELSEVLSISSDKLSSLINNHTTDHFLYLARQIDPTISKYISQLKLPGVYLQQGSK RYYPAGCATAHLIGVTDVDSQGIEGIEKSFDSWLTGQPKTRVIRKDRFGRTIEEITLNNGQSSQNIILSIDERLQDLAYR ELNNAVHMNKAESGSIVLIDINTGEILAMTNSPSYNPNNFLSIVNKSVMRNRAITDAFEPGSTVKPIVIMAALKHKIITK DTIMNTSPYILNGHQIKDVLYRRKLTIREILQKSSNVGVSKLALAMPAAVLVNTYSNFGMGKSTNIGLVGESNGIYPYNR CWSDIERATFSYGYGLMITPLQLAKVYATIGGMGISRPLSIIRVDSSSVLGNQVFPRSLVRTVLDMMENVSLPSGGCQSA IKGYRVAVKTGTVKIVGSHGKYINKYIACTAGVAPASNPRFALAVVINDPKNGHYYGSMVSAPVFSAVMGNALKIMNVVP DFLQ
Specific function: Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]
COG id: COG0768
COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2
Gene ontology:
Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side. Note=The bulk of the molecule, except for the N-terminal membrane anchor region, protrudes into the periplasmic space, where it acts on murein (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786272, Length=549, Percent_Identity=61.9307832422586, Blast_Score=711, Evalue=0.0, Organism=Escherichia coli, GI1786854, Length=613, Percent_Identity=22.8384991843393, Blast_Score=125, Evalue=8e-30,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR005311 - InterPro: IPR001460 [H]
Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]
EC number: =2.4.1.129 [H]
Molecular weight: Translated: 62255; Mature: 62255
Theoretical pI: Translated: 9.94; Mature: 9.94
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 3.0 %Met (Mature Protein) 3.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKFEPYNFKIILNNKRFNLLYSGIFFVLIILLLRLAFLQIIYSDQLINEGNMRSLRVQST CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHH LSTRGIITDRMGQLLAISIPADSVWIDPQEISKSGGITADIRRWTELSEVLSISSDKLSS HHHCCCHHHCCCCEEEEECCCCCEEECHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHH LINNHTTDHFLYLARQIDPTISKYISQLKLPGVYLQQGSKRYYPAGCATAHLIGVTDVDS HHHCCCCHHHHHHHHHCCHHHHHHHHHHCCCCHHHHCCCCEECCCCCCCEEEEEEECCCC QGIEGIEKSFDSWLTGQPKTRVIRKDRFGRTIEEITLNNGQSSQNIILSIDERLQDLAYR CCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHEECCCCCCCCEEEEHHHHHHHHHHH ELNNAVHMNKAESGSIVLIDINTGEILAMTNSPSYNPNNFLSIVNKSVMRNRAITDAFEP HHCCCEECCCCCCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCC GSTVKPIVIMAALKHKIITKDTIMNTSPYILNGHQIKDVLYRRKLTIREILQKSSNVGVS CCCCCHHHHHHHHHHHHHCHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHH KLALAMPAAVLVNTYSNFGMGKSTNIGLVGESNGIYPYNRCWSDIERATFSYGYGLMITP HHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEECH LQLAKVYATIGGMGISRPLSIIRVDSSSVLGNQVFPRSLVRTVLDMMENVSLPSGGCQSA HHHHHHHHHHCCCCCCCCEEEEEECCCHHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHH IKGYRVAVKTGTVKIVGSHGKYINKYIACTAGVAPASNPRFALAVVINDPKNGHYYGSMV HCCEEEEEEECEEEEEECCCHHHHHHHHEECCCCCCCCCCEEEEEEEECCCCCCEECCHH SAPVFSAVMGNALKIMNVVPDFLQ HHHHHHHHHHHHHHHHHHHHHHHC >Mature Secondary Structure MKFEPYNFKIILNNKRFNLLYSGIFFVLIILLLRLAFLQIIYSDQLINEGNMRSLRVQST CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHH LSTRGIITDRMGQLLAISIPADSVWIDPQEISKSGGITADIRRWTELSEVLSISSDKLSS HHHCCCHHHCCCCEEEEECCCCCEEECHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHH LINNHTTDHFLYLARQIDPTISKYISQLKLPGVYLQQGSKRYYPAGCATAHLIGVTDVDS HHHCCCCHHHHHHHHHCCHHHHHHHHHHCCCCHHHHCCCCEECCCCCCCEEEEEEECCCC QGIEGIEKSFDSWLTGQPKTRVIRKDRFGRTIEEITLNNGQSSQNIILSIDERLQDLAYR CCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHEECCCCCCCCEEEEHHHHHHHHHHH ELNNAVHMNKAESGSIVLIDINTGEILAMTNSPSYNPNNFLSIVNKSVMRNRAITDAFEP HHCCCEECCCCCCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCC GSTVKPIVIMAALKHKIITKDTIMNTSPYILNGHQIKDVLYRRKLTIREILQKSSNVGVS CCCCCHHHHHHHHHHHHHCHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHH KLALAMPAAVLVNTYSNFGMGKSTNIGLVGESNGIYPYNRCWSDIERATFSYGYGLMITP HHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEECH LQLAKVYATIGGMGISRPLSIIRVDSSSVLGNQVFPRSLVRTVLDMMENVSLPSGGCQSA HHHHHHHHHHCCCCCCCCEEEEEECCCHHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHH IKGYRVAVKTGTVKIVGSHGKYINKYIACTAGVAPASNPRFALAVVINDPKNGHYYGSMV HCCEEEEEEECEEEEEECCCHHHHHHHHEECCCCCCCCCCEEEEEEEECCCCCCEECCHH SAPVFSAVMGNALKIMNVVPDFLQ HHHHHHHHHHHHHHHHHHHHHHHC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]