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The map label for this gene is folB [H]

Identifier: 71891851

GI number: 71891851

Start: 73996

End: 74379

Strand: Direct

Name: folB [H]

Synonym: BPEN_062

Alternate gene names: 71891851

Gene position: 73996-74379 (Clockwise)

Preceding gene: 71891849

Following gene: 71891852

Centisome position: 9.35

GC content: 28.65

Gene sequence:

>384_bases
ATGATGGATATCTTATTTATCGATCGACTGACAGTAATGGCGTATATCGGTATAAATGATTGGGAAAAAAATTGTTTGCA
AAAATTAATTTTTGATTTGCAATTGTCATGTAATACTGAATTTTTTGAAGATCATCAAAGTGTAGTGTCTTATATTGATT
ATACTCATGTAAATCAAGTCATACTTAGTTTAGTGAGCCAGAAACATTTTTACTTAATAGAAGATGTTGCTAATTTAATA
GCAAACACATTGATAGAAAAATTTTGTATTTACTGGGTTCGTGTAAAAGTGAATAAACCTGGTGCAATTCATAATGCTTG
TAATGTTGGTATATGTGTTGAGCGAAAGAATAAAACACTTCTCAAGTCTTTAAAAAAGAGTTAG

Upstream 100 bases:

>100_bases
TTTAATAGCAATTATTGCATATATTTTACATATATATGTGTGTATATTAAATAGTCAATATCATTTAAATAAATAATTTT
TATGTAATTGAATATAATAT

Downstream 100 bases:

>100_bases
TTTGTTGAAAAGTGTATGGATGTATCTATAAGATAAGAAAAATTTTTAAATAAGTATAATTATTTCTATATACCATGAGT
AACGTGGTGATACATATGTC

Product: dihydroneopterin aldolase, also has dihydroneopterin triphosphate

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MMDILFIDRLTVMAYIGINDWEKNCLQKLIFDLQLSCNTEFFEDHQSVVSYIDYTHVNQVILSLVSQKHFYLIEDVANLI
ANTLIEKFCIYWVRVKVNKPGAIHNACNVGICVERKNKTLLKSLKKS

Sequences:

>Translated_127_residues
MMDILFIDRLTVMAYIGINDWEKNCLQKLIFDLQLSCNTEFFEDHQSVVSYIDYTHVNQVILSLVSQKHFYLIEDVANLI
ANTLIEKFCIYWVRVKVNKPGAIHNACNVGICVERKNKTLLKSLKKS
>Mature_127_residues
MMDILFIDRLTVMAYIGINDWEKNCLQKLIFDLQLSCNTEFFEDHQSVVSYIDYTHVNQVILSLVSQKHFYLIEDVANLI
ANTLIEKFCIYWVRVKVNKPGAIHNACNVGICVERKNKTLLKSLKKS

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. Can use L-threo-dihydroneopterin and D-erythro-dihydroneopterin as substrates for the formation of 6-hydroxymethyldihydropterin, but it can also catalyze the epimeriza

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

Organism=Escherichia coli, GI87082204, Length=116, Percent_Identity=37.9310344827586, Blast_Score=100, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 14772; Mature: 14772

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDILFIDRLTVMAYIGINDWEKNCLQKLIFDLQLSCNTEFFEDHQSVVSYIDYTHVNQV
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ILSLVSQKHFYLIEDVANLIANTLIEKFCIYWVRVKVNKPGAIHNACNVGICVERKNKTL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCEEEEECCCHHH
LKSLKKS
HHHHHCC
>Mature Secondary Structure
MMDILFIDRLTVMAYIGINDWEKNCLQKLIFDLQLSCNTEFFEDHQSVVSYIDYTHVNQV
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ILSLVSQKHFYLIEDVANLIANTLIEKFCIYWVRVKVNKPGAIHNACNVGICVERKNKTL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCEEEEECCCHHH
LKSLKKS
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]