Click here to switch to the map view.

The map label for this gene is gcp

Identifier: 71891849

GI number: 71891849

Start: 72239

End: 73264

Strand: Direct

Name: gcp

Synonym: BPEN_060

Alternate gene names: 71891849

Gene position: 72239-73264 (Clockwise)

Preceding gene: 71891845

Following gene: 71891851

Centisome position: 9.13

GC content: 36.84

Gene sequence:

>1026_bases
ATGCGTGTTTTAGGTATTGAAACTTCATGTGATGAAACAGGCGTAGCAATTTATGATCAACATAAAGGGTTATTAGCTAA
TGAAGTATATAGTCAAAGTGAATTGCATGCTGATTATGGCGGGGTTGTTCCTGAATTAGCTGCTCGTGATCATGTTCGAA
AAATAGTTCCTTTAATTTCATGTACACTAAATCGAGCGCGTTTAGAGCCAAAAAATATTGATGGAATAGCATACACTGCT
GGACCTGGATTGATGGGTGCCTTATTGGTCGGAGCAACTGTTGCTAGGACACTTGCGTATGCTTGGAAAATACCCGCTAT
CGATATTCATCATATGGAAGCTCATTTATTAGCGCCAATGTTAGAAAAAAAAGTTCCTACTTTTCCATTTATAGCATTAT
TAGTATCTGGCGGACACACTCAACTTGTGTCTGCAAGCAATATAGGGGAATATAAAATATTAGGAGAATCTATTGATGAT
GCTGTTGGAGAAGTGTTTGATAAGATTGCTATATTGTTAGGATTAAAATATCCTGGAGGAGCTTTATTATCAAAAATGGC
TCAGAAGGGTATTTCGAAGCGTTATGTATTTCCTCGTCCTATGATTGATCGCCCCGGTTTGAATTTTAGTTTTTCTGGTT
TAAAAACTTGTACGGTAAATACTATTATGTCAAATTCTCATGATGCTCAAAATTGTGCTGATATTGCACGTGCGTTTGAA
GATGCAATTATTGAAACATTAGCAATCAAATGTCGCCGTGCCTTAAATCAAACTGGATTAAAATGTTTAGTGATATCTGG
AGGTGTTAGCGCTAACCATGCGTTAAGGTCGTATCTTTTGAAGATGATGTATACCTTACAAGGAAGCTTGTTTTATCCTA
GACCGGAGTTTTGTACAGATAATGGCGCAATGGTGGCTTACGCTGGATTAATTAGACTAAAGGCTGGATTATTTAGTGAT
TTACCAATTTTAGTAAGACCACGCTGGTCATTAGAAGATCTTCCACGAATAAAGCAATCATTATAA

Upstream 100 bases:

>100_bases
ACTATATTTTTACTATTTTGTAATATAGCATTAAATATTATGACATGAAATATAAATAGTGTGAGTATTTTGTAATTGTC
AATTAAATATGGAGTATTAT

Downstream 100 bases:

>100_bases
TTTGCGTGTTAGTAATATTTTATGTTATTTACGCCAAATACGGTTTTCTTTGTGATGCCATAATCGTTTAATATTAGCTG
CATGCTTTATTACAACTAAA

Product: putative O-sialoglycoprotein endopeptidase

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MRVLGIETSCDETGVAIYDQHKGLLANEVYSQSELHADYGGVVPELAARDHVRKIVPLISCTLNRARLEPKNIDGIAYTA
GPGLMGALLVGATVARTLAYAWKIPAIDIHHMEAHLLAPMLEKKVPTFPFIALLVSGGHTQLVSASNIGEYKILGESIDD
AVGEVFDKIAILLGLKYPGGALLSKMAQKGISKRYVFPRPMIDRPGLNFSFSGLKTCTVNTIMSNSHDAQNCADIARAFE
DAIIETLAIKCRRALNQTGLKCLVISGGVSANHALRSYLLKMMYTLQGSLFYPRPEFCTDNGAMVAYAGLIRLKAGLFSD
LPILVRPRWSLEDLPRIKQSL

Sequences:

>Translated_341_residues
MRVLGIETSCDETGVAIYDQHKGLLANEVYSQSELHADYGGVVPELAARDHVRKIVPLISCTLNRARLEPKNIDGIAYTA
GPGLMGALLVGATVARTLAYAWKIPAIDIHHMEAHLLAPMLEKKVPTFPFIALLVSGGHTQLVSASNIGEYKILGESIDD
AVGEVFDKIAILLGLKYPGGALLSKMAQKGISKRYVFPRPMIDRPGLNFSFSGLKTCTVNTIMSNSHDAQNCADIARAFE
DAIIETLAIKCRRALNQTGLKCLVISGGVSANHALRSYLLKMMYTLQGSLFYPRPEFCTDNGAMVAYAGLIRLKAGLFSD
LPILVRPRWSLEDLPRIKQSL
>Mature_341_residues
MRVLGIETSCDETGVAIYDQHKGLLANEVYSQSELHADYGGVVPELAARDHVRKIVPLISCTLNRARLEPKNIDGIAYTA
GPGLMGALLVGATVARTLAYAWKIPAIDIHHMEAHLLAPMLEKKVPTFPFIALLVSGGHTQLVSASNIGEYKILGESIDD
AVGEVFDKIAILLGLKYPGGALLSKMAQKGISKRYVFPRPMIDRPGLNFSFSGLKTCTVNTIMSNSHDAQNCADIARAFE
DAIIETLAIKCRRALNQTGLKCLVISGGVSANHALRSYLLKMMYTLQGSLFYPRPEFCTDNGAMVAYAGLIRLKAGLFSD
LPILVRPRWSLEDLPRIKQSL

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=338, Percent_Identity=35.7988165680473, Blast_Score=185, Evalue=4e-47,
Organism=Homo sapiens, GI8923380, Length=322, Percent_Identity=31.055900621118, Blast_Score=125, Evalue=8e-29,
Organism=Escherichia coli, GI1789445, Length=335, Percent_Identity=69.5522388059701, Blast_Score=499, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17557464, Length=328, Percent_Identity=31.4024390243902, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71995670, Length=328, Percent_Identity=33.8414634146341, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320099, Length=370, Percent_Identity=34.3243243243243, Blast_Score=166, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6322891, Length=350, Percent_Identity=26, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI20129063, Length=338, Percent_Identity=34.9112426035503, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI21357207, Length=332, Percent_Identity=31.3253012048193, Blast_Score=134, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_BLOPB (Q493X8)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277578.1
- ProteinModelPortal:   Q493X8
- SMR:   Q493X8
- STRING:   Q493X8
- MEROPS:   M22.001
- GeneID:   3562953
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_060
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- BioCyc:   CBLO291272:BPEN_060-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 37138; Mature: 37138

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLGIETSCDETGVAIYDQHKGLLANEVYSQSELHADYGGVVPELAARDHVRKIVPLIS
CEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
CTLNRARLEPKNIDGIAYTAGPGLMGALLVGATVARTLAYAWKIPAIDIHHMEAHLLAPM
HHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHH
LEKKVPTFPFIALLVSGGHTQLVSASNIGEYKILGESIDDAVGEVFDKIAILLGLKYPGG
HHHCCCCCHHHHHHHCCCCEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCH
ALLSKMAQKGISKRYVFPRPMIDRPGLNFSFSGLKTCTVNTIMSNSHDAQNCADIARAFE
HHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCEEEEHHHHCCCCCHHHHHHHHHHHH
DAIIETLAIKCRRALNQTGLKCLVISGGVSANHALRSYLLKMMYTLQGSLFYPRPEFCTD
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCC
NGAMVAYAGLIRLKAGLFSDLPILVRPRWSLEDLPRIKQSL
CCCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure
MRVLGIETSCDETGVAIYDQHKGLLANEVYSQSELHADYGGVVPELAARDHVRKIVPLIS
CEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
CTLNRARLEPKNIDGIAYTAGPGLMGALLVGATVARTLAYAWKIPAIDIHHMEAHLLAPM
HHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHH
LEKKVPTFPFIALLVSGGHTQLVSASNIGEYKILGESIDDAVGEVFDKIAILLGLKYPGG
HHHCCCCCHHHHHHHCCCCEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCH
ALLSKMAQKGISKRYVFPRPMIDRPGLNFSFSGLKTCTVNTIMSNSHDAQNCADIARAFE
HHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCEEEEHHHHCCCCCHHHHHHHHHHHH
DAIIETLAIKCRRALNQTGLKCLVISGGVSANHALRSYLLKMMYTLQGSLFYPRPEFCTD
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCC
NGAMVAYAGLIRLKAGLFSDLPILVRPRWSLEDLPRIKQSL
CCCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA