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The map label for this gene is ubiA

Identifier: 71891817

GI number: 71891817

Start: 30037

End: 30909

Strand: Direct

Name: ubiA

Synonym: BPEN_025

Alternate gene names: 71891817

Gene position: 30037-30909 (Clockwise)

Preceding gene: 71891815

Following gene: 71891819

Centisome position: 3.79

GC content: 30.7

Gene sequence:

>873_bases
ATGTCAAACAGGCTTTTTTTTATCAAAAAGTGCTATAATTTAGCACAGTTAATGCGCATTAATCAACCTATTGGGTTTTT
TCTATTACTATGGCCTACTTTATGGGGGCTGTGGTTATCACACAAAGGTATCCCTGATAAAGTTGTTTTGATAGTGTTTG
TTGCCGGAGCACTGTGTATGCGCTCTGCAGGTTGTATAATCAATGATTATGTTGATTACGATATCGATGGTCATGTTCAA
CGTACTAAAACGCGTCCTTTACCATCTGGAATGATCAGGAAAAAAGAGGCATTAGTGGCGTTATCGATACTTCTTTTTAT
TGCATTCATATTGGTTTTAAGTTTGAATTTTATTACTATCTTTTTATCTGTAGTAGCCCTAATATTATCTTGGATATATC
CGTATCTTAAAAGATATATTTATTTTCCCCAAGTAATGTTAGGATTATTGTTTAGTTGGCCTATTTTAATGGCGTTTACT
GCAATTAATAATCCCATAAATAGTACTGCTTGGTTATTATTTCTAATGAATACTGTATGGACAATAGTATATGATACGCA
ATATGCTATGATAGATCGGGAAGATGATATATATGTTGGAATAAAGTCATCTGCTGTATTGTTTGGTGACATGGATAAAT
TTTTAATAGGAATATTGCAGTTATGTATTGTATTTATATTGGGAATTATTGGATGGAAGGAGAGATTTACTGTAGTATTT
TATTTTTTTTCATTATTTGGAGTCATCATATTATTTATGTGGCAACAAATATTAATTAATAAAAGAAAACGAATAAGATA
TTTTCAGGCTTTTTTAAGTAATAATTATGTAGGTATGTTAGTGTTCATAGGTATTGCTTCGAGTTTCCATTAA

Upstream 100 bases:

>100_bases
ATAAATATCCGCAATGCCATTCTATATACTATGATGATGATATCTATCATTGATAGTATTATCGGTAAAAGTTATAACGA
TTATATTATTTACTAATTTT

Downstream 100 bases:

>100_bases
TTTAAATATAATCAATTTCACTCTAAACAATAAGAATATGCAGGATAAACGTATTTAAATGAATACGATTGCTGTGTGTA
AGAAAATATTAATAATAAGT

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSNRLFFIKKCYNLAQLMRINQPIGFFLLLWPTLWGLWLSHKGIPDKVVLIVFVAGALCMRSAGCIINDYVDYDIDGHVQ
RTKTRPLPSGMIRKKEALVALSILLFIAFILVLSLNFITIFLSVVALILSWIYPYLKRYIYFPQVMLGLLFSWPILMAFT
AINNPINSTAWLLFLMNTVWTIVYDTQYAMIDREDDIYVGIKSSAVLFGDMDKFLIGILQLCIVFILGIIGWKERFTVVF
YFFSLFGVIILFMWQQILINKRKRIRYFQAFLSNNYVGMLVFIGIASSFH

Sequences:

>Translated_290_residues
MSNRLFFIKKCYNLAQLMRINQPIGFFLLLWPTLWGLWLSHKGIPDKVVLIVFVAGALCMRSAGCIINDYVDYDIDGHVQ
RTKTRPLPSGMIRKKEALVALSILLFIAFILVLSLNFITIFLSVVALILSWIYPYLKRYIYFPQVMLGLLFSWPILMAFT
AINNPINSTAWLLFLMNTVWTIVYDTQYAMIDREDDIYVGIKSSAVLFGDMDKFLIGILQLCIVFILGIIGWKERFTVVF
YFFSLFGVIILFMWQQILINKRKRIRYFQAFLSNNYVGMLVFIGIASSFH
>Mature_289_residues
SNRLFFIKKCYNLAQLMRINQPIGFFLLLWPTLWGLWLSHKGIPDKVVLIVFVAGALCMRSAGCIINDYVDYDIDGHVQR
TKTRPLPSGMIRKKEALVALSILLFIAFILVLSLNFITIFLSVVALILSWIYPYLKRYIYFPQVMLGLLFSWPILMAFTA
INNPINSTAWLLFLMNTVWTIVYDTQYAMIDREDDIYVGIKSSAVLFGDMDKFLIGILQLCIVFILGIIGWKERFTVVFY
FFSLFGVIILFMWQQILINKRKRIRYFQAFLSNNYVGMLVFIGIASSFH

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family

Homologues:

Organism=Homo sapiens, GI260656052, Length=274, Percent_Identity=35.036496350365, Blast_Score=162, Evalue=2e-40,
Organism=Escherichia coli, GI1790473, Length=274, Percent_Identity=50.3649635036496, Blast_Score=284, Evalue=5e-78,
Organism=Escherichia coli, GI1786631, Length=183, Percent_Identity=25.6830601092896, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17553718, Length=277, Percent_Identity=35.0180505415162, Blast_Score=160, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI32565247, Length=276, Percent_Identity=33.3333333333333, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17553720, Length=177, Percent_Identity=37.2881355932203, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI32565245, Length=135, Percent_Identity=41.4814814814815, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI32565243, Length=134, Percent_Identity=41.044776119403, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6324370, Length=276, Percent_Identity=30.4347826086957, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21355567, Length=275, Percent_Identity=40.7272727272727, Blast_Score=193, Evalue=9e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIA_BLOPB (Q494A7)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277546.1
- STRING:   Q494A7
- GeneID:   3563206
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_025
- eggNOG:   COG0382
- HOGENOM:   HBG324383
- OMA:   YHYTLIR
- ProtClustDB:   PRK12848
- BioCyc:   CBLO291272:BPEN_025-MONOMER
- HAMAP:   MF_01635
- InterPro:   IPR006370
- InterPro:   IPR000537
- TIGRFAMs:   TIGR01474

Pfam domain/function: PF01040 UbiA

EC number: 2.5.1.-

Molecular weight: Translated: 33678; Mature: 33547

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xea8fee8)-; HASH(0x107396d0)-; HASH(0xb77ed18)-; HASH(0x105f0068)-; HASH(0x10741d84)-; HASH(0x105f0104)-; HASH(0x107373b8)-; HASH(0x105f46d0)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNRLFFIKKCYNLAQLMRINQPIGFFLLLWPTLWGLWLSHKGIPDKVVLIVFVAGALCM
CCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
RSAGCIINDYVDYDIDGHVQRTKTRPLPSGMIRKKEALVALSILLFIAFILVLSLNFITI
HCCCCEEECCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLSVVALILSWIYPYLKRYIYFPQVMLGLLFSWPILMAFTAINNPINSTAWLLFLMNTVW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
TIVYDTQYAMIDREDDIYVGIKSSAVLFGDMDKFLIGILQLCIVFILGIIGWKERFTVVF
HHHCCCCEEEEECCCCEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
YFFSLFGVIILFMWQQILINKRKRIRYFQAFLSNNYVGMLVFIGIASSFH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCH
>Mature Secondary Structure 
SNRLFFIKKCYNLAQLMRINQPIGFFLLLWPTLWGLWLSHKGIPDKVVLIVFVAGALCM
CCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
RSAGCIINDYVDYDIDGHVQRTKTRPLPSGMIRKKEALVALSILLFIAFILVLSLNFITI
HCCCCEEECCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLSVVALILSWIYPYLKRYIYFPQVMLGLLFSWPILMAFTAINNPINSTAWLLFLMNTVW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
TIVYDTQYAMIDREDDIYVGIKSSAVLFGDMDKFLIGILQLCIVFILGIIGWKERFTVVF
HHHCCCCEEEEECCCCEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
YFFSLFGVIILFMWQQILINKRKRIRYFQAFLSNNYVGMLVFIGIASSFH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA