Click here to switch to the map view.

The map label for this gene is muT4 [H]

Identifier: 68537184

GI number: 68537184

Start: 2443186

End: 2443995

Strand: Direct

Name: muT4 [H]

Synonym: jk2089

Alternate gene names: 68537184

Gene position: 2443186-2443995 (Clockwise)

Preceding gene: 68537178

Following gene: 68537185

Centisome position: 99.22

GC content: 65.8

Gene sequence:

>810_bases
ATGAGTGGAAACGACAGCACCGGAAACGGCACGCCCCGCCGCCGGCGCCGCCGTTCCAGAAGAAAGCACCGCCCTGGCAA
CGGCCAGCGCGGCCAAAACTCCCAGCAGCAAGGCTCCCAGGCCAGCCAGCGCAGCCAGAACAGCCAACAGCAGCGCGGCC
AGAACTCCCAGAACAGCTCCAACCAGGGCAAACGCAAGAGCAACCGGAACCAAACCCACCGCAGGAAGGGCGCCAGCCCC
AATAGTCGCAACCGCCAACGCAGCCGCAACAACTCGCGCCCGCGCTCTTTCGACGAGCACTCGAGCCTGCCGACCTCCGT
GGAGACATCCGCGGGCGGCCTGGTGCTTTCCGGCCTGGCGGAAGCAGTGCAGCCAAATGGCGAGGTTGATTTCTCCGCAA
TCTACGTAGCCCTTATCGGCCGCCTGGACCGCCGCGGCAGGTTGCTGTGGTCCATGCCGAAAGGGCACATTGAACCCGAT
GAATCCCAGCACGCCACCGCCGAGCGCGAGGTGTGGGAGGAAACGGGCGTGGCCGGGGAGGTCATCGCGGACCTCGGCAC
CATCGACTACTGGTTTGTCTCCGAGGGCATCCGCATCCACAAAACCGTCCACCACCACCTGCTTCGCTACGTCGATGGCG
ACCTGAATGACGAGGATCCAGAGGTCACCGAGGTCCGCTGGCTGCCCGTCAACCGCCTGATCGAGCACCTGGCCTATGCT
GACGAGCGGCGCCTTGCCCGCCAAGCTTTCGACAGTCTCGCTGACCTGGCGCGCGCGGAAGCCGAAGCTGGCCGTGCCAC
GCCACGCTAG

Upstream 100 bases:

>100_bases
CACTGCAATTCGCCTCCATTCAGTTCCATTCGCCTCCAGTGGCGTCCTTTCGCTGCCATTCAGTTCCACATTGTGCAGAT
AACCGTCTATCGTTATCAGA

Downstream 100 bases:

>100_bases
AGATCACTAACGGATTGCCAGCCCAGACTGTTAGAACTAATAGCGATCAACAACTACTAATCACGAGCTACCAATTGCTT
AGGTGAGCGCAATGTCTAGA

Product: NUDIX domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSGNDSTGNGTPRRRRRRSRRKHRPGNGQRGQNSQQQGSQASQRSQNSQQQRGQNSQNSSNQGKRKSNRNQTHRRKGASP
NSRNRQRSRNNSRPRSFDEHSSLPTSVETSAGGLVLSGLAEAVQPNGEVDFSAIYVALIGRLDRRGRLLWSMPKGHIEPD
ESQHATAEREVWEETGVAGEVIADLGTIDYWFVSEGIRIHKTVHHHLLRYVDGDLNDEDPEVTEVRWLPVNRLIEHLAYA
DERRLARQAFDSLADLARAEAEAGRATPR

Sequences:

>Translated_269_residues
MSGNDSTGNGTPRRRRRRSRRKHRPGNGQRGQNSQQQGSQASQRSQNSQQQRGQNSQNSSNQGKRKSNRNQTHRRKGASP
NSRNRQRSRNNSRPRSFDEHSSLPTSVETSAGGLVLSGLAEAVQPNGEVDFSAIYVALIGRLDRRGRLLWSMPKGHIEPD
ESQHATAEREVWEETGVAGEVIADLGTIDYWFVSEGIRIHKTVHHHLLRYVDGDLNDEDPEVTEVRWLPVNRLIEHLAYA
DERRLARQAFDSLADLARAEAEAGRATPR
>Mature_268_residues
SGNDSTGNGTPRRRRRRSRRKHRPGNGQRGQNSQQQGSQASQRSQNSQQQRGQNSQNSSNQGKRKSNRNQTHRRKGASPN
SRNRQRSRNNSRPRSFDEHSSLPTSVETSAGGLVLSGLAEAVQPNGEVDFSAIYVALIGRLDRRGRLLWSMPKGHIEPDE
SQHATAEREVWEETGVAGEVIADLGTIDYWFVSEGIRIHKTVHHHLLRYVDGDLNDEDPEVTEVRWLPVNRLIEHLAYAD
ERRLARQAFDSLADLARAEAEAGRATPR

Specific function: May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool. In vitro has dATPase rather than 8-oxo-dGTPase activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 30292; Mature: 30160

Theoretical pI: Translated: 11.09; Mature: 11.09

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNDSTGNGTPRRRRRRSRRKHRPGNGQRGQNSQQQGSQASQRSQNSQQQRGQNSQNSS
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
NQGKRKSNRNQTHRRKGASPNSRNRQRSRNNSRPRSFDEHSSLPTSVETSAGGLVLSGLA
CCCHHHHCCHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHH
EAVQPNGEVDFSAIYVALIGRLDRRGRLLWSMPKGHIEPDESQHATAEREVWEETGVAGE
HHHCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHH
VIADLGTIDYWFVSEGIRIHKTVHHHLLRYVDGDLNDEDPEVTEVRWLPVNRLIEHLAYA
HHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHH
DERRLARQAFDSLADLARAEAEAGRATPR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SGNDSTGNGTPRRRRRRSRRKHRPGNGQRGQNSQQQGSQASQRSQNSQQQRGQNSQNSS
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
NQGKRKSNRNQTHRRKGASPNSRNRQRSRNNSRPRSFDEHSSLPTSVETSAGGLVLSGLA
CCCHHHHCCHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHH
EAVQPNGEVDFSAIYVALIGRLDRRGRLLWSMPKGHIEPDESQHATAEREVWEETGVAGE
HHHCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHH
VIADLGTIDYWFVSEGIRIHKTVHHHLLRYVDGDLNDEDPEVTEVRWLPVNRLIEHLAYA
HHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHH
DERRLARQAFDSLADLARAEAEAGRATPR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]