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The map label for this gene is fepC [H]

Identifier: 68536907

GI number: 68536907

Start: 2120757

End: 2121860

Strand: Direct

Name: fepC [H]

Synonym: jk1817

Alternate gene names: 68536907

Gene position: 2120757-2121860 (Clockwise)

Preceding gene: 68536906

Following gene: 68536908

Centisome position: 86.12

GC content: 62.32

Gene sequence:

>1104_bases
ATGGGGCTCAACAAGACTTCGCGCAATAGGCTCACCGCTACCGAGCGGGTTCCAGGCCGTCCGGCATTCAGGGTCGGGCC
AATCTCCTTCGTTTGGCGCCCACGAGTGCTGCTTGTATGCCTCATTGCCGCGGCCCTTATCGTTTTCTTGGGAGCATTTT
CCATTGGACTAGGTGATTTCCCCATCTCCGTTTCCCGAGTGCTGGAGGTTGTCTTCCGCGGGGATGGAAACCGCGTGGAA
AGGCTAGTGGTCCTGGACTGGCGCATGCCCCGTGTGGCAACCGCCATCGCGGTCGGCAGTGCTTTGGGGCTTTCTGGCGC
GCTAACTCAGACAGTCACCCGCAACGCACTGGCCAGCCCGGATATCCTTGGTATCACCACGGGCGCCTCAGCCATGGCCG
TGACGGTCATCGTCCTCGGCGGTGGCAGCGGATTTCTCAGCTGGCTGTCCGGAATCGGAATCCCTCTGGCCGCACTACTA
GGGGCGATACTCAGCGCTACAGCGATCTGGGCACTGGCGTGGCGGCGCCAGGCGGATTCCTACCGACTAGTGCTCTTTGG
CATCATCATCACCGCGCTGCTCAGTTCCTACATCAATTTCCTTATGATCCGCTCGGAGCTACGGAATGCTACCCAAGCGC
AGTTCTGGCTCACAGGCTCCTTGGCCACAGCGGGCTGGAATACCACCATCCCGATGGTGATTCTGGTGATCGCGTGCTGT
CCCCTACTGGCCTGGATCGGCTACCAGGCGCTGGCCACCACTTTGGGACCCGATCTGGCTCGGGCACTCGGCCAGCGGGT
CAACGGTGTACAGGTCGCGATGCTGGCGCTGGCCGTGGCCCTAGCTGCGGTAGCAGTCTCCGCCGCCGGCCCCATCGGCT
TCGTCGCCTTCGTAGCACCCCAGGTGGCCCTTCGAATGTGCGGCGTACCCACCCCACCGCTTGCGGCTTCGGCGCTCACC
GGTGCAGTACTGCTGCTGGGGGCGGACATCGTCACCCAAGCGATTCTGCCGGTGGAACTTCCGGTGGGCATTGTGACCTC
CGCCCTAGGTGGCATCTTCCTCATCTATCTGCTCGTTCAACGCACTAGGAGCACAGACGCATGA

Upstream 100 bases:

>100_bases
TCGCCCGGCCCGGCGAGCTCCAGGTGGGCATTGTGCTGGCGTTCGTGGGTGCACCGTTCTTCATCGTCTTGATTTACCGA
AAGAAGGTGGCGACGCTCTG

Downstream 100 bases:

>100_bases
CCTCTTCCACACCCCAGCCAAATACAGCACAGCACAACACGGCACTACCAAATACAGCACAGCCAAGCGACACCAGCGGC
GTAGTTGCGTCCTCGATCAC

Product: putative iron ABC transport system, permease protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MGLNKTSRNRLTATERVPGRPAFRVGPISFVWRPRVLLVCLIAAALIVFLGAFSIGLGDFPISVSRVLEVVFRGDGNRVE
RLVVLDWRMPRVATAIAVGSALGLSGALTQTVTRNALASPDILGITTGASAMAVTVIVLGGGSGFLSWLSGIGIPLAALL
GAILSATAIWALAWRRQADSYRLVLFGIIITALLSSYINFLMIRSELRNATQAQFWLTGSLATAGWNTTIPMVILVIACC
PLLAWIGYQALATTLGPDLARALGQRVNGVQVAMLALAVALAAVAVSAAGPIGFVAFVAPQVALRMCGVPTPPLAASALT
GAVLLLGADIVTQAILPVELPVGIVTSALGGIFLIYLLVQRTRSTDA

Sequences:

>Translated_367_residues
MGLNKTSRNRLTATERVPGRPAFRVGPISFVWRPRVLLVCLIAAALIVFLGAFSIGLGDFPISVSRVLEVVFRGDGNRVE
RLVVLDWRMPRVATAIAVGSALGLSGALTQTVTRNALASPDILGITTGASAMAVTVIVLGGGSGFLSWLSGIGIPLAALL
GAILSATAIWALAWRRQADSYRLVLFGIIITALLSSYINFLMIRSELRNATQAQFWLTGSLATAGWNTTIPMVILVIACC
PLLAWIGYQALATTLGPDLARALGQRVNGVQVAMLALAVALAAVAVSAAGPIGFVAFVAPQVALRMCGVPTPPLAASALT
GAVLLLGADIVTQAILPVELPVGIVTSALGGIFLIYLLVQRTRSTDA
>Mature_366_residues
GLNKTSRNRLTATERVPGRPAFRVGPISFVWRPRVLLVCLIAAALIVFLGAFSIGLGDFPISVSRVLEVVFRGDGNRVER
LVVLDWRMPRVATAIAVGSALGLSGALTQTVTRNALASPDILGITTGASAMAVTVIVLGGGSGFLSWLSGIGIPLAALLG
AILSATAIWALAWRRQADSYRLVLFGIIITALLSSYINFLMIRSELRNATQAQFWLTGSLATAGWNTTIPMVILVIACCP
LLAWIGYQALATTLGPDLARALGQRVNGVQVAMLALAVALAAVAVSAAGPIGFVAFVAPQVALRMCGVPTPPLAASALTG
AVLLLGADIVTQAILPVELPVGIVTSALGGIFLIYLLVQRTRSTDA

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4779

COG function: function code P; ABC-type enterobactin transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786804, Length=335, Percent_Identity=37.6119402985075, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1790740, Length=288, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1786347, Length=288, Percent_Identity=34.0277777777778, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1788004, Length=289, Percent_Identity=32.1799307958478, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790741, Length=336, Percent_Identity=28.2738095238095, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786805, Length=316, Percent_Identity=34.4936708860759, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 38186; Mature: 38055

Theoretical pI: Translated: 11.53; Mature: 11.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLNKTSRNRLTATERVPGRPAFRVGPISFVWRPRVLLVCLIAAALIVFLGAFSIGLGDF
CCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PISVSRVLEVVFRGDGNRVERLVVLDWRMPRVATAIAVGSALGLSGALTQTVTRNALASP
CHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
DILGITTGASAMAVTVIVLGGGSGFLSWLSGIGIPLAALLGAILSATAIWALAWRRQADS
CEEEEECCCHHEEEEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
YRLVLFGIIITALLSSYINFLMIRSELRNATQAQFWLTGSLATAGWNTTIPMVILVIACC
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCCHHHHHHHHHHHH
PLLAWIGYQALATTLGPDLARALGQRVNGVQVAMLALAVALAAVAVSAAGPIGFVAFVAP
HHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
QVALRMCGVPTPPLAASALTGAVLLLGADIVTQAILPVELPVGIVTSALGGIFLIYLLVQ
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHH
RTRSTDA
HHCCCCC
>Mature Secondary Structure 
GLNKTSRNRLTATERVPGRPAFRVGPISFVWRPRVLLVCLIAAALIVFLGAFSIGLGDF
CCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PISVSRVLEVVFRGDGNRVERLVVLDWRMPRVATAIAVGSALGLSGALTQTVTRNALASP
CHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
DILGITTGASAMAVTVIVLGGGSGFLSWLSGIGIPLAALLGAILSATAIWALAWRRQADS
CEEEEECCCHHEEEEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
YRLVLFGIIITALLSSYINFLMIRSELRNATQAQFWLTGSLATAGWNTTIPMVILVIACC
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCCHHHHHHHHHHHH
PLLAWIGYQALATTLGPDLARALGQRVNGVQVAMLALAVALAAVAVSAAGPIGFVAFVAP
HHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
QVALRMCGVPTPPLAASALTGAVLLLGADIVTQAILPVELPVGIVTSALGGIFLIYLLVQ
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHH
RTRSTDA
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1838574; 9278503 [H]