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The map label for this gene is kdpE [H]

Identifier: 68536354

GI number: 68536354

Start: 1498497

End: 1499189

Strand: Direct

Name: kdpE [H]

Synonym: jk1273

Alternate gene names: 68536354

Gene position: 1498497-1499189 (Clockwise)

Preceding gene: 68536353

Following gene: 68536355

Centisome position: 60.85

GC content: 63.2

Gene sequence:

>693_bases
ATGAGCGGCGAACAGATTTTGATGGTCGAAGATGACGTAGCGCTAGCTAACGCGGTGCTAGTAACCCTGCGGGCGCGCGG
CTACGACGTACAGGTAGCGACGACGGCGACGAAGGCGATTCAGGTGGCCTCGAAGTGGCATCCGCAGGCGGTGCTGCTAG
ACCTGGGACTGCCGGATCTGAGTGGCCTGGAGGTGCTGCGCGCGCTACGAAATTGGACGGATATTCCGGTGCTGATAGTT
TCCGCGCGCCACGACGAGTCGGGCAAGATCAACGCGCTGGACGAGGGCGCGGACGATTACGTGACCAAGCCATTTTCTGT
CGGCGAGCTGCTGGCCCGGCTGCGCGCGGCGCTGCGTAGAGCGCCCGGCGCGCCGATCCCGGAGGAGCCCGTGGTGGAGA
CCTCTGACAGACGCGTGGTGTTTGATCTACCGAACCAGCGGGTGACCGTCGACGGGCAGGACGTGCACCTGACCCCGCGC
GAATGGGGCATTGCCGAGCACATGATCCGCCACCGGGGAACGCTGGTGACGAAGGTCGAGTTGCTGCAGGCGGTGTGGGG
GCAGGCCTACAAGAAGGAGACGAATTACCTGCGGGTCTATATCTCTCAGTTGAGGTCGAAGCTGGAGGTCGATCCGAGTA
ACCCGCAGTACTTCACGACCGAGACGGGCATTGGCTATCGCCTGGTGCTGTGA

Upstream 100 bases:

>100_bases
GTGGAGGCGCCACACTGGTTCTATCCCTGCCAACGGCAACGGGGGAATCAGAAGATGGGGAAGAGCGTGGCGTCCAGAAG
AAGGTACAAGGAGAAGCGCC

Downstream 100 bases:

>100_bases
CGGGGTGCCGCCGGCGCCGGCGAAGGGTCAACCAACACCGCGAATGAGTTCACCTGGTGGCCATGTTGCCTTAAACCTGG
CGCAAAAAAGAGGTGGAAAT

Product: two-component system response regulator KdpE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSGEQILMVEDDVALANAVLVTLRARGYDVQVATTATKAIQVASKWHPQAVLLDLGLPDLSGLEVLRALRNWTDIPVLIV
SARHDESGKINALDEGADDYVTKPFSVGELLARLRAALRRAPGAPIPEEPVVETSDRRVVFDLPNQRVTVDGQDVHLTPR
EWGIAEHMIRHRGTLVTKVELLQAVWGQAYKKETNYLRVYISQLRSKLEVDPSNPQYFTTETGIGYRLVL

Sequences:

>Translated_230_residues
MSGEQILMVEDDVALANAVLVTLRARGYDVQVATTATKAIQVASKWHPQAVLLDLGLPDLSGLEVLRALRNWTDIPVLIV
SARHDESGKINALDEGADDYVTKPFSVGELLARLRAALRRAPGAPIPEEPVVETSDRRVVFDLPNQRVTVDGQDVHLTPR
EWGIAEHMIRHRGTLVTKVELLQAVWGQAYKKETNYLRVYISQLRSKLEVDPSNPQYFTTETGIGYRLVL
>Mature_229_residues
SGEQILMVEDDVALANAVLVTLRARGYDVQVATTATKAIQVASKWHPQAVLLDLGLPDLSGLEVLRALRNWTDIPVLIVS
ARHDESGKINALDEGADDYVTKPFSVGELLARLRAALRRAPGAPIPEEPVVETSDRRVVFDLPNQRVTVDGQDVHLTPRE
WGIAEHMIRHRGTLVTKVELLQAVWGQAYKKETNYLRVYISQLRSKLEVDPSNPQYFTTETGIGYRLVL

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=43.8053097345133, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=32.1739130434783, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=31.1111111111111, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=34.9557522123894, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=33.0357142857143, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=31.2775330396476, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=31.3304721030043, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=31.1688311688312, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=29.7777777777778, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=27.8026905829596, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=30.5309734513274, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=30.8695652173913, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=29.6943231441048, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=29.9065420560748, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25614; Mature: 25482

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGEQILMVEDDVALANAVLVTLRARGYDVQVATTATKAIQVASKWHPQAVLLDLGLPDL
CCCCEEEEEECCHHHHHHEEEEEECCCCEEEEEEHHHHHHHHHHCCCCCEEEEECCCCCC
SGLEVLRALRNWTDIPVLIVSARHDESGKINALDEGADDYVTKPFSVGELLARLRAALRR
HHHHHHHHHHCCCCCEEEEEEECCCCCCCEEECCCCCCHHCCCCCCHHHHHHHHHHHHHH
APGAPIPEEPVVETSDRRVVFDLPNQRVTVDGQDVHLTPREWGIAEHMIRHRGTLVTKVE
CCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCEEEECCHHCCHHHHHHHHCCCHHHHHH
LLQAVWGQAYKKETNYLRVYISQLRSKLEVDPSNPQYFTTETGIGYRLVL
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEC
>Mature Secondary Structure 
SGEQILMVEDDVALANAVLVTLRARGYDVQVATTATKAIQVASKWHPQAVLLDLGLPDL
CCCEEEEEECCHHHHHHEEEEEECCCCEEEEEEHHHHHHHHHHCCCCCEEEEECCCCCC
SGLEVLRALRNWTDIPVLIVSARHDESGKINALDEGADDYVTKPFSVGELLARLRAALRR
HHHHHHHHHHCCCCCEEEEEEECCCCCCCEEECCCCCCHHCCCCCCHHHHHHHHHHHHHH
APGAPIPEEPVVETSDRRVVFDLPNQRVTVDGQDVHLTPREWGIAEHMIRHRGTLVTKVE
CCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCEEEECCHHCCHHHHHHHHCCCHHHHHH
LLQAVWGQAYKKETNYLRVYISQLRSKLEVDPSNPQYFTTETGIGYRLVL
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]