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The map label for this gene is pepE [H]

Identifier: 68536320

GI number: 68536320

Start: 1458021

End: 1459112

Strand: Direct

Name: pepE [H]

Synonym: jk1241

Alternate gene names: 68536320

Gene position: 1458021-1459112 (Clockwise)

Preceding gene: 68536319

Following gene: 68536322

Centisome position: 59.21

GC content: 62.45

Gene sequence:

>1092_bases
ATGAGTGAATTCTTCCCAACCGAAACGTTTAGCAAGCGTCTTGCCACCGTCCGCGACATCGCCGCACAGGCGGGCCTGGA
CGGCGTGATCGTTACCCCCGGTCCGGACATGGAGTACCTGATCTCGTCGAAGATCACCACCCACGAGCGGTTCACGGCTC
TGGTTCTTACTCAGGACGCCGCACGCATCATCGTCCCCGGCGTGGATGTAGCAGACCTGAAGAAGTCCGTGGCGGGCAAG
CTCGGTGTGGAGATCATCGGGTGGAACGACGGCGAAGACCCCTACGGCTATATCACCGAAGGCTCCTACGCTGTCAGCGG
CGCAATGACCGCCGATCACCTGCTGGAACTGCAGTCCCGCGGTATCTCCACCGTCAACGCCACCCAGGTGCTCGCCCAGG
CGTTCATCCGCAAGGACGACGAAGAGCTCTCCGAGCTGCGCCGCGCAAGCGCTGCCATCGACGCAGTCCACCGCCAGGTC
CCGAACCTGCTGCGCGCAGGCGTGACCGAGAATGACGTGGCCAAGGAACTGGAGCGCCTCATCCTCGAAGAGCACGAGGT
TGTGGACTTCATCATCGTCGGCTCCGGCCCGCACGGCGCGGACCCGCACCACGATCACTCCGATCGCGTCATCGAGTCCG
GCGACGTGGTGGTCGTCGACATCGGCGGCACCCTGGCCAGCGGCTACCACTCGGACTGCACCCGCACCTACGTTGTTGGC
GAGCCCACGGACGAGCAGCAAAAGATCTACGACGTACTGCAGCGCGCCCAGGAGGCCGGGTTGGAATTCGCCAAGCCCGG
CGTGACGGCCGGCGAAGTCGACAAGGTCGTCCGCGACATCATCGAAGAAGCTGGCTACGGCGAGTACTTCATCCACCGCA
CCGGCCACGGCATCGGGCTTTCCTGCCACGAAGAGCCATTCATCATCGCCGGCAACGACTTTGTGATTGAAGAAGGCATG
GCATTCTCCATTGAACCCGGCATCTACATCCCCGGTCAGTGGGGCGCACGCATCGAAGACATTGTGATTGTGGCGTCCAA
AAATGTAGAGCCCATAAACAAGACACCCCACGAGCTTGTGCGCGTGGGGTGA

Upstream 100 bases:

>100_bases
TGGGAGGCACAAGAACTTGTGGCGAAGTCCTGCCGGCAACTGCTACCAGCCACCCCACACCCCACCGCTCCCCCACACCC
CGGGGCGTACCCTGGTGGCC

Downstream 100 bases:

>100_bases
GAACCGGCGGGCTGGATGCCCTAGCTGAAACTAGCGGACATCCACGAACAGCTTAAGGATCCACTTGCGGGCCAGGAACA
TGACCGCGCCCAGGCCGACC

Product: putative dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSEFFPTETFSKRLATVRDIAAQAGLDGVIVTPGPDMEYLISSKITTHERFTALVLTQDAARIIVPGVDVADLKKSVAGK
LGVEIIGWNDGEDPYGYITEGSYAVSGAMTADHLLELQSRGISTVNATQVLAQAFIRKDDEELSELRRASAAIDAVHRQV
PNLLRAGVTENDVAKELERLILEEHEVVDFIIVGSGPHGADPHHDHSDRVIESGDVVVVDIGGTLASGYHSDCTRTYVVG
EPTDEQQKIYDVLQRAQEAGLEFAKPGVTAGEVDKVVRDIIEEAGYGEYFIHRTGHGIGLSCHEEPFIIAGNDFVIEEGM
AFSIEPGIYIPGQWGARIEDIVIVASKNVEPINKTPHELVRVG

Sequences:

>Translated_363_residues
MSEFFPTETFSKRLATVRDIAAQAGLDGVIVTPGPDMEYLISSKITTHERFTALVLTQDAARIIVPGVDVADLKKSVAGK
LGVEIIGWNDGEDPYGYITEGSYAVSGAMTADHLLELQSRGISTVNATQVLAQAFIRKDDEELSELRRASAAIDAVHRQV
PNLLRAGVTENDVAKELERLILEEHEVVDFIIVGSGPHGADPHHDHSDRVIESGDVVVVDIGGTLASGYHSDCTRTYVVG
EPTDEQQKIYDVLQRAQEAGLEFAKPGVTAGEVDKVVRDIIEEAGYGEYFIHRTGHGIGLSCHEEPFIIAGNDFVIEEGM
AFSIEPGIYIPGQWGARIEDIVIVASKNVEPINKTPHELVRVG
>Mature_362_residues
SEFFPTETFSKRLATVRDIAAQAGLDGVIVTPGPDMEYLISSKITTHERFTALVLTQDAARIIVPGVDVADLKKSVAGKL
GVEIIGWNDGEDPYGYITEGSYAVSGAMTADHLLELQSRGISTVNATQVLAQAFIRKDDEELSELRRASAAIDAVHRQVP
NLLRAGVTENDVAKELERLILEEHEVVDFIIVGSGPHGADPHHDHSDRVIESGDVVVVDIGGTLASGYHSDCTRTYVVGE
PTDEQQKIYDVLQRAQEAGLEFAKPGVTAGEVDKVVRDIIEEAGYGEYFIHRTGHGIGLSCHEEPFIIAGNDFVIEEGMA
FSIEPGIYIPGQWGARIEDIVIVASKNVEPINKTPHELVRVG

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI264681563, Length=262, Percent_Identity=29.3893129770992, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI93141226, Length=176, Percent_Identity=33.5227272727273, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI40385867, Length=170, Percent_Identity=27.0588235294118, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI264681565, Length=259, Percent_Identity=28.957528957529, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI11559925, Length=181, Percent_Identity=28.1767955801105, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788728, Length=233, Percent_Identity=37.3390557939914, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1789275, Length=310, Percent_Identity=27.4193548387097, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1786364, Length=125, Percent_Identity=29.6, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 39392; Mature: 39260

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFFPTETFSKRLATVRDIAAQAGLDGVIVTPGPDMEYLISSKITTHERFTALVLTQDA
CCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHCCCCCHHHEEEEEEECCC
ARIIVPGVDVADLKKSVAGKLGVEIIGWNDGEDPYGYITEGSYAVSGAMTADHLLELQSR
CEEEECCCCHHHHHHHHHHHCCEEEEECCCCCCCCEEEECCCEEEECCHHHHHHHHHHHC
GISTVNATQVLAQAFIRKDDEELSELRRASAAIDAVHRQVPNLLRAGVTENDVAKELERL
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ILEEHEVVDFIIVGSGPHGADPHHDHSDRVIESGDVVVVDIGGTLASGYHSDCTRTYVVG
HHHCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCEEEEECCCHHCCCCCCCCCEEEEEC
EPTDEQQKIYDVLQRAQEAGLEFAKPGVTAGEVDKVVRDIIEEAGYGEYFIHRTGHGIGL
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCE
SCHEEPFIIAGNDFVIEEGMAFSIEPGIYIPGQWGARIEDIVIVASKNVEPINKTPHELV
EECCCCEEEECCCEEEECCCEEEECCCEEECCCCCCCEEEEEEEECCCCCCCCCCHHHHH
RVG
CCC
>Mature Secondary Structure 
SEFFPTETFSKRLATVRDIAAQAGLDGVIVTPGPDMEYLISSKITTHERFTALVLTQDA
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHCCCCCHHHEEEEEEECCC
ARIIVPGVDVADLKKSVAGKLGVEIIGWNDGEDPYGYITEGSYAVSGAMTADHLLELQSR
CEEEECCCCHHHHHHHHHHHCCEEEEECCCCCCCCEEEECCCEEEECCHHHHHHHHHHHC
GISTVNATQVLAQAFIRKDDEELSELRRASAAIDAVHRQVPNLLRAGVTENDVAKELERL
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ILEEHEVVDFIIVGSGPHGADPHHDHSDRVIESGDVVVVDIGGTLASGYHSDCTRTYVVG
HHHCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCEEEEECCCHHCCCCCCCCCEEEEEC
EPTDEQQKIYDVLQRAQEAGLEFAKPGVTAGEVDKVVRDIIEEAGYGEYFIHRTGHGIGL
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCE
SCHEEPFIIAGNDFVIEEGMAFSIEPGIYIPGQWGARIEDIVIVASKNVEPINKTPHELV
EECCCCEEEECCCEEEECCCEEEECCCEEECCCCCCCEEEEEEEECCCCCCCCCCHHHHH
RVG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]