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The map label for this gene is agaR [H]

Identifier: 68536184

GI number: 68536184

Start: 1305538

End: 1306350

Strand: Direct

Name: agaR [H]

Synonym: jk1107

Alternate gene names: 68536184

Gene position: 1305538-1306350 (Clockwise)

Preceding gene: 68536183

Following gene: 68536186

Centisome position: 53.02

GC content: 60.89

Gene sequence:

>813_bases
ATGGAATCAGCAGAGCGGCGCCGCCAGATACTTTCCCTCACAGCCATTCATGGCAGGGTGACTGTGAATGAGCTGGCGGA
GAAGTTCGGCGTCACCGCAGAAACAATTCGTCGTGACCTGGCGATCCTCGACGACGGCGGTGAGCTCTTCCGCGTCCACG
GGGGCGCCGTCCCCGTGCAGAACTTTCGCACTGACTTCACCACGCTCGCAACCAGGTCCAAAGCCGCACTCGGGGCCAAG
CGCGCCATTGCCCAAGCGGCCGTACAGCTATTGCCCTTCTCGGGCACCGTCTTCATCGACGCAGGCACTACCACTGGGGT
GTTCGCCGAAGCAATCGCGGCGGCCAACGCCGCAAACGATCCGAAACTCATGGCTCCAAAGCTGAACATCGTAACAAACT
CGTTGTTCATCGCGACTACCTTGGCGGAATCACCACGCTTTGACGTACAGCTGATCGGCGGACACGTTCGTTCAGCCTCC
CAGGCCGTTGTCGGCGACCTTGCCACCCGCGCTCTTGGCGTGCTGCACGCAGACGTAGCCTTTATCGGCACCAACGCGCT
CACCATCGAGCACGGTCTCTCCACCCCCGACGCTCAAGAGGGGGCGATCAAGCGCGCTATGGTCGCCAACTCCGATTCCG
TGGTCGCTCTGTGTGATTCCACCAAGTTTGGTCTCGATTACCTCGTCAGCTTCGCCAGCATCGAGGACATCGCTGCCATC
GTCACCGACCGCAACGCACCGGAGCCCTACGTATACGAACTGCGACACCTCGGCATCAAAGTCACGTTCGCCGAAGACGC
GCCAAAGGACTAG

Upstream 100 bases:

>100_bases
CAATTCTGGGCAAGGTTGCCGCGGTCCTGCGCAAGATCTAAGTCCCCCCCATTGGCTCTGACGCCGCCTTTTCGGCCCGC
TAGCAACTAAAATGACCTTC

Downstream 100 bases:

>100_bases
CTACTCGGCGACGACAAACTGCTCCAGCTCGGCCGCAACAACCTTCGGTAGGCGAACGTTCAGACGCGTCCCGTCTGCAT
CGTAGTCCTCTTCAAGCACC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MESAERRRQILSLTAIHGRVTVNELAEKFGVTAETIRRDLAILDDGGELFRVHGGAVPVQNFRTDFTTLATRSKAALGAK
RAIAQAAVQLLPFSGTVFIDAGTTTGVFAEAIAAANAANDPKLMAPKLNIVTNSLFIATTLAESPRFDVQLIGGHVRSAS
QAVVGDLATRALGVLHADVAFIGTNALTIEHGLSTPDAQEGAIKRAMVANSDSVVALCDSTKFGLDYLVSFASIEDIAAI
VTDRNAPEPYVYELRHLGIKVTFAEDAPKD

Sequences:

>Translated_270_residues
MESAERRRQILSLTAIHGRVTVNELAEKFGVTAETIRRDLAILDDGGELFRVHGGAVPVQNFRTDFTTLATRSKAALGAK
RAIAQAAVQLLPFSGTVFIDAGTTTGVFAEAIAAANAANDPKLMAPKLNIVTNSLFIATTLAESPRFDVQLIGGHVRSAS
QAVVGDLATRALGVLHADVAFIGTNALTIEHGLSTPDAQEGAIKRAMVANSDSVVALCDSTKFGLDYLVSFASIEDIAAI
VTDRNAPEPYVYELRHLGIKVTFAEDAPKD
>Mature_270_residues
MESAERRRQILSLTAIHGRVTVNELAEKFGVTAETIRRDLAILDDGGELFRVHGGAVPVQNFRTDFTTLATRSKAALGAK
RAIAQAAVQLLPFSGTVFIDAGTTTGVFAEAIAAANAANDPKLMAPKLNIVTNSLFIATTLAESPRFDVQLIGGHVRSAS
QAVVGDLATRALGVLHADVAFIGTNALTIEHGLSTPDAQEGAIKRAMVANSDSVVALCDSTKFGLDYLVSFASIEDIAAI
VTDRNAPEPYVYELRHLGIKVTFAEDAPKD

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=265, Percent_Identity=31.6981132075472, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789829, Length=250, Percent_Identity=32, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI87082344, Length=261, Percent_Identity=28.3524904214559, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787540, Length=251, Percent_Identity=28.2868525896414, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI226510968, Length=256, Percent_Identity=30.46875, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789059, Length=270, Percent_Identity=28.5185185185185, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788069, Length=265, Percent_Identity=28.3018867924528, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790635, Length=261, Percent_Identity=25.6704980842912, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790753, Length=265, Percent_Identity=24.9056603773585, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28572; Mature: 28572

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESAERRRQILSLTAIHGRVTVNELAEKFGVTAETIRRDLAILDDGGELFRVHGGAVPVQ
CCCHHHHHHHHHHHHHCCEEEHHHHHHHHCCCHHHHHHHHEEEECCCCEEEEECCCCCHH
NFRTDFTTLATRSKAALGAKRAIAQAAVQLLPFSGTVFIDAGTTTGVFAEAIAAANAAND
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCCC
PKLMAPKLNIVTNSLFIATTLAESPRFDVQLIGGHVRSASQAVVGDLATRALGVLHADVA
CCEECCCHHEEECCEEEEEECCCCCCCEEEEECCHHCCHHHHHHHHHHHHHHHHHHHHHH
FIGTNALTIEHGLSTPDAQEGAIKRAMVANSDSVVALCDSTKFGLDYLVSFASIEDIAAI
EECCCEEEEECCCCCCCCHHHHHHHHHEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
VTDRNAPEPYVYELRHLGIKVTFAEDAPKD
HCCCCCCCHHHHHHHHCCEEEEECCCCCCC
>Mature Secondary Structure
MESAERRRQILSLTAIHGRVTVNELAEKFGVTAETIRRDLAILDDGGELFRVHGGAVPVQ
CCCHHHHHHHHHHHHHCCEEEHHHHHHHHCCCHHHHHHHHEEEECCCCEEEEECCCCCHH
NFRTDFTTLATRSKAALGAKRAIAQAAVQLLPFSGTVFIDAGTTTGVFAEAIAAANAAND
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCCC
PKLMAPKLNIVTNSLFIATTLAESPRFDVQLIGGHVRSASQAVVGDLATRALGVLHADVA
CCEECCCHHEEECCEEEEEECCCCCCCEEEEECCHHCCHHHHHHHHHHHHHHHHHHHHHH
FIGTNALTIEHGLSTPDAQEGAIKRAMVANSDSVVALCDSTKFGLDYLVSFASIEDIAAI
EECCCEEEEECCCCCCCCHHHHHHHHHEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
VTDRNAPEPYVYELRHLGIKVTFAEDAPKD
HCCCCCCCHHHHHHHHCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]