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The map label for this gene is galE [H]

Identifier: 68536175

GI number: 68536175

Start: 1289721

End: 1290755

Strand: Direct

Name: galE [H]

Synonym: jk1098

Alternate gene names: 68536175

Gene position: 1289721-1290755 (Clockwise)

Preceding gene: 68536174

Following gene: 68536177

Centisome position: 52.37

GC content: 59.71

Gene sequence:

>1035_bases
GTGGGGAATGTGAGTAGCATCGATCTTTCCTCTTCCTCCCTGTCCCCCTCATCCCACATTGTCGTCACCGGTGGCGCCGG
ATACGTAGGCAGTGTGTGCGCCAGCGTGCTGCTGGAGCACGGCTTCCGCGTAACGGTTGTTGATGACCTTTCCACTGGCA
ACGGATACGCCGTGCCGGACGGAGCGACCTTCGTTGAAGGCGACATCCGTGACGTAATCTCCGATGTCTTCGCGACCGGT
GACGTAGCTGCCGTGATGCATTTTGCCGCCCGCTCTCTGGTCGGCGAGTCCGTAGAAAAACCGGACATCTACTGGCACCA
CAATGTGGGCACCAGCCTGTATCTGCTGGATCAGATGCGTGAGCACGGCGTGCAGAACCTCGTGTTCTCCTCCACCGCAG
CCACCTATGGGGAACCCGAACAGGTACCCATTACCGAAGATATGCCCACTGCTCCCACCAACCCCTATGGTGCATCCAAG
CTGGCGATCGACCACATGATCACCTCCTACGCTAACGCCTATGGGCTGGCCGCAACCTCACTGCGCTACTTCAACGTCGC
CGGTGCATACGGCGACATTGGTGAGAACCACAAGGTAGAGACACACCTGATCCCGTTGGTGCTGCAGGTTGCCCTCGGCC
ACCGGGAACACATATCCATCTTCGGCACCGACTACCCCACCGCTGACGGAACCGCAGTGCGCGATTACATTCACATTCGG
GATCTGGCGGACGCCCACTTGCTTGCTGCGGCTTCCAACACCGCTGGACAACACCGTATCTTCAACCTTGGCTCCGGCGA
TGGCTTCAGCGTGCGCCAGGTTATCGATACATGCCGCGAGGTGACTGGCCATCCGATTCCTGCGGTAGAGTCCCCTCGCC
GCGCGGGCGACCCTGCCACCCTCATCGCCTCCTCCGCAAAGGCGAAGGCTGAACTCGGCTGGAACCCGACCCGCTCCGAC
CTACACACGATCATTTCAGATGCATGGTCGTTTAGCGGACAACTGGGTGATAGGTTGCATTCCGCACAGCGTTAA

Upstream 100 bases:

>100_bases
GACGGCCTGGAGTTCAGTAACGACAACGGCGCCATGGTGGTTCCAGAAGAACTCGGCCACGCCGTGCGGGTAGAGAAAGT
CAACTAATTGGTGCGGTAGC

Downstream 100 bases:

>100_bases
TCGCGTCCCAGTCGACCGTTTGTAGCAGGCGCTCGTATTCCCAGGCGAGGTCTAGTCCGGCATACTCCCGGACTGTGACG
TAGGAGCGCTCCGGAACCCA

Product: hypothetical protein

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MGNVSSIDLSSSSLSPSSHIVVTGGAGYVGSVCASVLLEHGFRVTVVDDLSTGNGYAVPDGATFVEGDIRDVISDVFATG
DVAAVMHFAARSLVGESVEKPDIYWHHNVGTSLYLLDQMREHGVQNLVFSSTAATYGEPEQVPITEDMPTAPTNPYGASK
LAIDHMITSYANAYGLAATSLRYFNVAGAYGDIGENHKVETHLIPLVLQVALGHREHISIFGTDYPTADGTAVRDYIHIR
DLADAHLLAAASNTAGQHRIFNLGSGDGFSVRQVIDTCREVTGHPIPAVESPRRAGDPATLIASSAKAKAELGWNPTRSD
LHTIISDAWSFSGQLGDRLHSAQR

Sequences:

>Translated_344_residues
MGNVSSIDLSSSSLSPSSHIVVTGGAGYVGSVCASVLLEHGFRVTVVDDLSTGNGYAVPDGATFVEGDIRDVISDVFATG
DVAAVMHFAARSLVGESVEKPDIYWHHNVGTSLYLLDQMREHGVQNLVFSSTAATYGEPEQVPITEDMPTAPTNPYGASK
LAIDHMITSYANAYGLAATSLRYFNVAGAYGDIGENHKVETHLIPLVLQVALGHREHISIFGTDYPTADGTAVRDYIHIR
DLADAHLLAAASNTAGQHRIFNLGSGDGFSVRQVIDTCREVTGHPIPAVESPRRAGDPATLIASSAKAKAELGWNPTRSD
LHTIISDAWSFSGQLGDRLHSAQR
>Mature_343_residues
GNVSSIDLSSSSLSPSSHIVVTGGAGYVGSVCASVLLEHGFRVTVVDDLSTGNGYAVPDGATFVEGDIRDVISDVFATGD
VAAVMHFAARSLVGESVEKPDIYWHHNVGTSLYLLDQMREHGVQNLVFSSTAATYGEPEQVPITEDMPTAPTNPYGASKL
AIDHMITSYANAYGLAATSLRYFNVAGAYGDIGENHKVETHLIPLVLQVALGHREHISIFGTDYPTADGTAVRDYIHIRD
LADAHLLAAASNTAGQHRIFNLGSGDGFSVRQVIDTCREVTGHPIPAVESPRRAGDPATLIASSAKAKAELGWNPTRSDL
HTIISDAWSFSGQLGDRLHSAQR

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=40.5882352941176, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=40.5882352941176, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=40.5882352941176, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI7657641, Length=268, Percent_Identity=26.865671641791, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI42516563, Length=307, Percent_Identity=25.0814332247557, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1786974, Length=331, Percent_Identity=39.8791540785499, Blast_Score=231, Evalue=4e-62,
Organism=Escherichia coli, GI1788353, Length=336, Percent_Identity=28.2738095238095, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI48994969, Length=332, Percent_Identity=28.0120481927711, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790049, Length=262, Percent_Identity=29.3893129770992, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=338, Percent_Identity=36.094674556213, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI71982038, Length=340, Percent_Identity=35.8823529411765, Blast_Score=194, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI115532424, Length=332, Percent_Identity=25, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17568069, Length=276, Percent_Identity=27.8985507246377, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17507723, Length=334, Percent_Identity=24.251497005988, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=346, Percent_Identity=37.2832369942197, Blast_Score=205, Evalue=7e-54,
Organism=Drosophila melanogaster, GI19923002, Length=338, Percent_Identity=36.6863905325444, Blast_Score=197, Evalue=9e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36552; Mature: 36421

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNVSSIDLSSSSLSPSSHIVVTGGAGYVGSVCASVLLEHGFRVTVVDDLSTGNGYAVPD
CCCCCEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCEECCC
GATFVEGDIRDVISDVFATGDVAAVMHFAARSLVGESVEKPDIYWHHNVGTSLYLLDQMR
CCEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHH
EHGVQNLVFSSTAATYGEPEQVPITEDMPTAPTNPYGASKLAIDHMITSYANAYGLAATS
HCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LRYFNVAGAYGDIGENHKVETHLIPLVLQVALGHREHISIFGTDYPTADGTAVRDYIHIR
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHH
DLADAHLLAAASNTAGQHRIFNLGSGDGFSVRQVIDTCREVTGHPIPAVESPRRAGDPAT
HHCCHHHEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
LIASSAKAKAELGWNPTRSDLHTIISDAWSFSGQLGDRLHSAQR
EEECCCCCHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCC
>Mature Secondary Structure 
GNVSSIDLSSSSLSPSSHIVVTGGAGYVGSVCASVLLEHGFRVTVVDDLSTGNGYAVPD
CCCCEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCEECCC
GATFVEGDIRDVISDVFATGDVAAVMHFAARSLVGESVEKPDIYWHHNVGTSLYLLDQMR
CCEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHH
EHGVQNLVFSSTAATYGEPEQVPITEDMPTAPTNPYGASKLAIDHMITSYANAYGLAATS
HCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LRYFNVAGAYGDIGENHKVETHLIPLVLQVALGHREHISIFGTDYPTADGTAVRDYIHIR
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHH
DLADAHLLAAASNTAGQHRIFNLGSGDGFSVRQVIDTCREVTGHPIPAVESPRRAGDPAT
HHCCHHHEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
LIASSAKAKAELGWNPTRSDLHTIISDAWSFSGQLGDRLHSAQR
EEECCCCCHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2116013; 14602910 [H]