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The map label for this gene is obgE

Identifier: 68535634

GI number: 68535634

Start: 681619

End: 683130

Strand: Direct

Name: obgE

Synonym: jk0562

Alternate gene names: 68535634

Gene position: 681619-683130 (Clockwise)

Preceding gene: 68535630

Following gene: 68535635

Centisome position: 27.68

GC content: 63.49

Gene sequence:

>1512_bases
ATGCCACAATTCGTTGATCGCGTAGTGCTGCATTTGCAGGCCGGTGACGGCGGCCACGGCTGCGCTTCTGTTCACCGCGA
AAAGTTCGTCCCTCTCGGCGGCCCCGATGGAGGTAACGGCGGCCACGGCGGAGACATCATCTTGGAAGTCTCCTCACAGG
TGCACACCCTGTTGGACTTCCACTTCCACCCTCACATCAAGGCTCAGCGCGGCAACAACGGCGCTGGCGATCACCGACAC
GGTGCGCGCGGGGAAGACCTCGTACTCCAAGTGCCGGAAGGCACCGTTGTGCTTAACTCCAAGGGCGAGGCAATTGCCGA
CCTGACAGGCAAGGGTACGCGGATGATCGTCGCCGCGGGCGGACATGGCGGGTTGGGGAACGCGGCGTTGGCGTCCAAAA
GCAGGAAAGCCCCGGGTTTCGCGCTGCTGGGCGAACCTGGCGAGGCAAAAGACGTCATCCTCGAACTTAAGTCCATGGCA
GACGTTGGCCTGGTTGGCTTCCCATCGGCGGGTAAGAGCTCGCTGATTTCCGTGCTGTCGGCCGCGAAGCCGAAGATCGC
GGACTACCCGTTTACGACCCTGGTGCCGAACCTGGGCGTGGTCAACGTTGGCCACGAGGTGTTTACCGTAGCTGACGTGC
CGGGCCTGATCCCCGGTGCGAGCGAAGGCAAAGGCCTGGGACTGGATTTCCTGCGCCACATCGAACGCACTGCCGTTCTG
GCCCATGTCGTCGACGCCGCCTCGCTGGAAGCAGACCGCGATCCTGTTGCGGACATCAAGGCCCTGGAAAAGGAGCTGGC
CAACTATCAAGAGGAGCTGGCCAGCGACTCCGGGCTGGGCGACCTGCGCGAACGTCCGCGGGTGATCATCCTGAACAAGA
TGGACGTGCCAGACGCTGCAGACATGGCCGATCTGCAGGAGGAAGAACTCAAGGAATTCGGCTGGCCGATCTTCCGCATT
TCCACGGTTGCGCACAAGGGCTTGGACGAGCTGAAGTACGCGCTAATGGATATTGTGAAGGCCCACCGCAAGGCGAACCC
CGTGGAGGAGAAGCCCGCGCAGGTCATTACGCCGAAGGGGCTGCGCAAGCGCTCCGGCGGACGGTTCGCCGAGTTCGAAG
TGGAAGCGGATCCGTCCGCCGAGGATGCCTTCATCGTCCGTGGCGAGAAGATCGAACGCTGGATCCGGCAGACCGACTTC
GAAAATGACGAGGCAGTGGGCTACCTGGCCGACCGACTGGCCAAGGCCGGTGTGGAGGAAGCGCTTTACAAGGCCGGCGC
GGATGCAGGCAGCGAGGTAACAATCGGAGAGATCACCTTCGAATGGGACCCACAGACCGCCGCCGGTGTGGACGTGATGC
GCAGCGGACGCGGCACCGACGTCCGCCTCGAGCAGAACACCCGCGCCACCCCGGAGGAGCGCAAGCGTGCCTCGCAAGCC
CGCCGTGGCCTGATCGACGAGAACGATTTCGGCGATGGCGAGGTCGCAGAGCGCGAACGTTGGCAGGGGTAG

Upstream 100 bases:

>100_bases
ACAGGGTTCGGATTCTCCACCTTTTAGGCCGCTACCCCAAACACAGATAGACTCGGAGCTCGAAGTATTAATTGGGGCGA
AAAGAAAGCAAGGGAAAGCT

Downstream 100 bases:

>100_bases
CCAGGTTGTACCAAACGGCACAAGGCCGGGGAGTGGGCTGGCATACTGGAGAGTATGTCATCCTCCGATTCCGACATTGC
AGACGAAAACGAGTTCAGTT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 503; Mature: 502

Protein sequence:

>503_residues
MPQFVDRVVLHLQAGDGGHGCASVHREKFVPLGGPDGGNGGHGGDIILEVSSQVHTLLDFHFHPHIKAQRGNNGAGDHRH
GARGEDLVLQVPEGTVVLNSKGEAIADLTGKGTRMIVAAGGHGGLGNAALASKSRKAPGFALLGEPGEAKDVILELKSMA
DVGLVGFPSAGKSSLISVLSAAKPKIADYPFTTLVPNLGVVNVGHEVFTVADVPGLIPGASEGKGLGLDFLRHIERTAVL
AHVVDAASLEADRDPVADIKALEKELANYQEELASDSGLGDLRERPRVIILNKMDVPDAADMADLQEEELKEFGWPIFRI
STVAHKGLDELKYALMDIVKAHRKANPVEEKPAQVITPKGLRKRSGGRFAEFEVEADPSAEDAFIVRGEKIERWIRQTDF
ENDEAVGYLADRLAKAGVEEALYKAGADAGSEVTIGEITFEWDPQTAAGVDVMRSGRGTDVRLEQNTRATPEERKRASQA
RRGLIDENDFGDGEVAERERWQG

Sequences:

>Translated_503_residues
MPQFVDRVVLHLQAGDGGHGCASVHREKFVPLGGPDGGNGGHGGDIILEVSSQVHTLLDFHFHPHIKAQRGNNGAGDHRH
GARGEDLVLQVPEGTVVLNSKGEAIADLTGKGTRMIVAAGGHGGLGNAALASKSRKAPGFALLGEPGEAKDVILELKSMA
DVGLVGFPSAGKSSLISVLSAAKPKIADYPFTTLVPNLGVVNVGHEVFTVADVPGLIPGASEGKGLGLDFLRHIERTAVL
AHVVDAASLEADRDPVADIKALEKELANYQEELASDSGLGDLRERPRVIILNKMDVPDAADMADLQEEELKEFGWPIFRI
STVAHKGLDELKYALMDIVKAHRKANPVEEKPAQVITPKGLRKRSGGRFAEFEVEADPSAEDAFIVRGEKIERWIRQTDF
ENDEAVGYLADRLAKAGVEEALYKAGADAGSEVTIGEITFEWDPQTAAGVDVMRSGRGTDVRLEQNTRATPEERKRASQA
RRGLIDENDFGDGEVAERERWQG
>Mature_502_residues
PQFVDRVVLHLQAGDGGHGCASVHREKFVPLGGPDGGNGGHGGDIILEVSSQVHTLLDFHFHPHIKAQRGNNGAGDHRHG
ARGEDLVLQVPEGTVVLNSKGEAIADLTGKGTRMIVAAGGHGGLGNAALASKSRKAPGFALLGEPGEAKDVILELKSMAD
VGLVGFPSAGKSSLISVLSAAKPKIADYPFTTLVPNLGVVNVGHEVFTVADVPGLIPGASEGKGLGLDFLRHIERTAVLA
HVVDAASLEADRDPVADIKALEKELANYQEELASDSGLGDLRERPRVIILNKMDVPDAADMADLQEEELKEFGWPIFRIS
TVAHKGLDELKYALMDIVKAHRKANPVEEKPAQVITPKGLRKRSGGRFAEFEVEADPSAEDAFIVRGEKIERWIRQTDFE
NDEAVGYLADRLAKAGVEEALYKAGADAGSEVTIGEITFEWDPQTAAGVDVMRSGRGTDVRLEQNTRATPEERKRASQAR
RGLIDENDFGDGEVAERERWQG

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=344, Percent_Identity=37.7906976744186, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI111955139, Length=292, Percent_Identity=38.6986301369863, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI111955063, Length=194, Percent_Identity=41.2371134020619, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI58761500, Length=135, Percent_Identity=31.8518518518519, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI4557537, Length=158, Percent_Identity=38.6075949367089, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1789574, Length=341, Percent_Identity=42.5219941348974, Blast_Score=245, Evalue=4e-66,
Organism=Escherichia coli, GI1787454, Length=129, Percent_Identity=32.5581395348837, Blast_Score=69, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=329, Percent_Identity=38.2978723404255, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17552324, Length=333, Percent_Identity=28.2282282282282, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=32.8125, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=163, Percent_Identity=40.4907975460123, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6321612, Length=109, Percent_Identity=39.4495412844037, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6319281, Length=108, Percent_Identity=37.962962962963, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129375, Length=318, Percent_Identity=37.7358490566038, Blast_Score=160, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24585318, Length=304, Percent_Identity=35.8552631578947, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24640873, Length=148, Percent_Identity=32.4324324324324, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24640877, Length=148, Percent_Identity=32.4324324324324, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24640875, Length=148, Percent_Identity=32.4324324324324, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21356473, Length=151, Percent_Identity=36.4238410596026, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_CORJK (Q4JWT6)

Other databases:

- EMBL:   CR931997
- RefSeq:   YP_250339.1
- HSSP:   P20964
- ProteinModelPortal:   Q4JWT6
- SMR:   Q4JWT6
- STRING:   Q4JWT6
- GeneID:   3432843
- GenomeReviews:   CR931997_GR
- KEGG:   cjk:jk0562
- NMPDR:   fig|306537.3.peg.558
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   HFTTLVP
- ProtClustDB:   PRK12296
- BioCyc:   CJEI306537:JK0562-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 53875; Mature: 53744

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQFVDRVVLHLQAGDGGHGCASVHREKFVPLGGPDGGNGGHGGDIILEVSSQVHTLLDF
CCHHHEEHEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHH
HFHPHIKAQRGNNGAGDHRHGARGEDLVLQVPEGTVVLNSKGEAIADLTGKGTRMIVAAG
HCCCCEEEECCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCEEEECCCCCCEEEEEEC
GHGGLGNAALASKSRKAPGFALLGEPGEAKDVILELKSMADVGLVGFPSAGKSSLISVLS
CCCCCCCHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHH
AAKPKIADYPFTTLVPNLGVVNVGHEVFTVADVPGLIPGASEGKGLGLDFLRHIERTAVL
HCCCCCCCCCHHHHCCCCCEEECCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AHVVDAASLEADRDPVADIKALEKELANYQEELASDSGLGDLRERPRVIILNKMDVPDAA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEECCCCCCCC
DMADLQEEELKEFGWPIFRISTVAHKGLDELKYALMDIVKAHRKANPVEEKPAQVITPKG
HHHHCCHHHHHHHCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCC
LRKRSGGRFAEFEVEADPSAEDAFIVRGEKIERWIRQTDFENDEAVGYLADRLAKAGVEE
HHHCCCCCEEEEEECCCCCCCCEEEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ALYKAGADAGSEVTIGEITFEWDPQTAAGVDVMRSGRGTDVRLEQNTRATPEERKRASQA
HHHHCCCCCCCEEEEEEEEEEECCCCHHCHHHHHCCCCCEEEECCCCCCCHHHHHHHHHH
RRGLIDENDFGDGEVAERERWQG
HHCCCCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure 
PQFVDRVVLHLQAGDGGHGCASVHREKFVPLGGPDGGNGGHGGDIILEVSSQVHTLLDF
CHHHEEHEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHH
HFHPHIKAQRGNNGAGDHRHGARGEDLVLQVPEGTVVLNSKGEAIADLTGKGTRMIVAAG
HCCCCEEEECCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCEEEECCCCCCEEEEEEC
GHGGLGNAALASKSRKAPGFALLGEPGEAKDVILELKSMADVGLVGFPSAGKSSLISVLS
CCCCCCCHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHH
AAKPKIADYPFTTLVPNLGVVNVGHEVFTVADVPGLIPGASEGKGLGLDFLRHIERTAVL
HCCCCCCCCCHHHHCCCCCEEECCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AHVVDAASLEADRDPVADIKALEKELANYQEELASDSGLGDLRERPRVIILNKMDVPDAA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEECCCCCCCC
DMADLQEEELKEFGWPIFRISTVAHKGLDELKYALMDIVKAHRKANPVEEKPAQVITPKG
HHHHCCHHHHHHHCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCC
LRKRSGGRFAEFEVEADPSAEDAFIVRGEKIERWIRQTDFENDEAVGYLADRLAKAGVEE
HHHCCCCCEEEEEECCCCCCCCEEEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ALYKAGADAGSEVTIGEITFEWDPQTAAGVDVMRSGRGTDVRLEQNTRATPEERKRASQA
HHHHCCCCCCCEEEEEEEEEEECCCCHHCHHHHHCCCCCEEEECCCCCCCHHHHHHHHHH
RRGLIDENDFGDGEVAERERWQG
HHCCCCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA