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The map label for this gene is pgm [H]

Identifier: 68535538

GI number: 68535538

Start: 572165

End: 573820

Strand: Direct

Name: pgm [H]

Synonym: jk0468

Alternate gene names: 68535538

Gene position: 572165-573820 (Clockwise)

Preceding gene: 68535536

Following gene: 68535539

Centisome position: 23.24

GC content: 64.07

Gene sequence:

>1656_bases
ATGCACCCACGTGCTGGCCAGCCCGCCACCCCCGACGACCTCACCGACATCCCAGCCCTCCTGGAGGCTTACTCCGCCAC
GGTTCCGAATCTGGCTGACCCAGGCCAGCGCGTGAGCTTCGGTACCTCCGGTCACCGCGGTAGCGCCTTCGACGGTGCCT
TCAATGAGGCGCACATCCTGGCCACTACCCAAGCCATCGTCGATTACCGCCGTGAGCAGGGCATCAACGGTCCCATCTTC
ATCGGTCGCGACCCACACGCGCTTTCCGAACCGGCCGAGGCCACCGCACTGGAGGTGCTGGCCGGAAACCGCGTGAACGT
GATGGTGGACCAGGAGCGCGGGTTTGTACCCACCCCGTCCATTAGCTTCGCCATCCTGGAATACAACAAGCAGCTGCCTG
GAGGCCCGGAGGGCACCGACGCTGGTCGCGCCGACGGCATCGTCGTCACCCCTTCCCACAACCCGCCGCGCGACGGTGGC
TTTAAGTACAACCCGCCGACGGGCGGCCCTGCGGATACCGATGCGACCAGCTGGATCGCCCGCCGCGCCAACGAGTACCT
GGATGCGGATCTGTCTGGCGTGCAGCGCTCCACCTCCACTGAACTGGTGGAAAACCACAATTACCTGGGCAATTACGTTG
CTGCGCTGCCGGAGGTCATCGACATTGAGGCCGTTCGTAGCGCGGGCGTGCGCATCGGCGCCGACCCGATGGGCGGTGCC
TCCGTTGCCTACTGGGAGCGCATCGCCGACGTACACGGCCTGGACCTCACGGTCGTCAACCCCACCATCGACCCGGCCTT
CGGGTTCATGACCTTGGACTCTGACGGCAAGATCCGCATGGATTGCTCCTCGCCGTCCGCGATGGCCTCTCTGGTCGACG
CTGTTGCAGGCGCCGGTGGGGCTTCCTATGACATCGCTACTGGTAATGACGCCGATTCCGACCGCCATGGAATCGTCACC
CCAGATGCAGGCCTGATGAACCCGAACCACTACCTCGCTGTCGCTATCGAGTACCTCTTTAGCCATCGCGAGAACTGGCC
GCAGGATGCCGCCGTGGGTAAGACCCTGGTCAGTTCCTCCATGATCGACCGCGTGGTGGCCCGCATGGGCCGCAAGCTGA
TGGAAGTTCCGGTTGGGTTCAAGTGGTTCGTGCCGGGGCTGGTCAACGGATCCGTGGGCTTTGGTGGAGAAGAATCGGCA
GGTGCTTCCTTCCTTCGCCACAACGGGCAGGTTTGGTCTACCGATAAGGACGGTATTATCGCTGACCTGTTGGCGTCCGA
AATCAAGGCAACGACCGGCAAGAGCCCGTCCGAGCGCTACAAGGAGCTAGCCGAGGAGCTGGGCGCGCCGCAGTACAAGC
GCATCGACGCTCCGGCCAACCGCGAGCAAAAGGAGCGTCTCAAGAAGCTCAGCGCCAGCGACGTGGAGGCCACCGAGCTG
GCGGGCGAGAAAATCGAGGCGATCCTGACCGAGGCGCCGGGCAACGGCGCGGCAATCGGTGGGGTGAAGGTGACTACCGA
AAATGCCTGGTTCGCCGCCCGCCCGAGTGGCACGGAGGATAAGTACAAGATCTACGCGGAGTCCTTTAATGGCGCCGAGC
ACCTGGACAAGGTCCTGGAGGAAGCGCAGGTCGTCGTCGACGGCGTGCTCGGGTAG

Upstream 100 bases:

>100_bases
GTTAAAAGGGCGGTGTAGCACTGAAAAACCTGCCGGAATCGGGCACGATAAATGGTGAGTAGCAAGAAAATGCTTTCAGG
CACCGACCGAAGGAATCATC

Downstream 100 bases:

>100_bases
CTTCTTGCTTTCCTGCAAGTATGCGTAAAATCACGGGGTCGATTCAGGGGATTGCCAGAAACCTGCGATACGCTCATGCC
CAGTAGACACGTCATCATCT

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MHPRAGQPATPDDLTDIPALLEAYSATVPNLADPGQRVSFGTSGHRGSAFDGAFNEAHILATTQAIVDYRREQGINGPIF
IGRDPHALSEPAEATALEVLAGNRVNVMVDQERGFVPTPSISFAILEYNKQLPGGPEGTDAGRADGIVVTPSHNPPRDGG
FKYNPPTGGPADTDATSWIARRANEYLDADLSGVQRSTSTELVENHNYLGNYVAALPEVIDIEAVRSAGVRIGADPMGGA
SVAYWERIADVHGLDLTVVNPTIDPAFGFMTLDSDGKIRMDCSSPSAMASLVDAVAGAGGASYDIATGNDADSDRHGIVT
PDAGLMNPNHYLAVAIEYLFSHRENWPQDAAVGKTLVSSSMIDRVVARMGRKLMEVPVGFKWFVPGLVNGSVGFGGEESA
GASFLRHNGQVWSTDKDGIIADLLASEIKATTGKSPSERYKELAEELGAPQYKRIDAPANREQKERLKKLSASDVEATEL
AGEKIEAILTEAPGNGAAIGGVKVTTENAWFAARPSGTEDKYKIYAESFNGAEHLDKVLEEAQVVVDGVLG

Sequences:

>Translated_551_residues
MHPRAGQPATPDDLTDIPALLEAYSATVPNLADPGQRVSFGTSGHRGSAFDGAFNEAHILATTQAIVDYRREQGINGPIF
IGRDPHALSEPAEATALEVLAGNRVNVMVDQERGFVPTPSISFAILEYNKQLPGGPEGTDAGRADGIVVTPSHNPPRDGG
FKYNPPTGGPADTDATSWIARRANEYLDADLSGVQRSTSTELVENHNYLGNYVAALPEVIDIEAVRSAGVRIGADPMGGA
SVAYWERIADVHGLDLTVVNPTIDPAFGFMTLDSDGKIRMDCSSPSAMASLVDAVAGAGGASYDIATGNDADSDRHGIVT
PDAGLMNPNHYLAVAIEYLFSHRENWPQDAAVGKTLVSSSMIDRVVARMGRKLMEVPVGFKWFVPGLVNGSVGFGGEESA
GASFLRHNGQVWSTDKDGIIADLLASEIKATTGKSPSERYKELAEELGAPQYKRIDAPANREQKERLKKLSASDVEATEL
AGEKIEAILTEAPGNGAAIGGVKVTTENAWFAARPSGTEDKYKIYAESFNGAEHLDKVLEEAQVVVDGVLG
>Mature_551_residues
MHPRAGQPATPDDLTDIPALLEAYSATVPNLADPGQRVSFGTSGHRGSAFDGAFNEAHILATTQAIVDYRREQGINGPIF
IGRDPHALSEPAEATALEVLAGNRVNVMVDQERGFVPTPSISFAILEYNKQLPGGPEGTDAGRADGIVVTPSHNPPRDGG
FKYNPPTGGPADTDATSWIARRANEYLDADLSGVQRSTSTELVENHNYLGNYVAALPEVIDIEAVRSAGVRIGADPMGGA
SVAYWERIADVHGLDLTVVNPTIDPAFGFMTLDSDGKIRMDCSSPSAMASLVDAVAGAGGASYDIATGNDADSDRHGIVT
PDAGLMNPNHYLAVAIEYLFSHRENWPQDAAVGKTLVSSSMIDRVVARMGRKLMEVPVGFKWFVPGLVNGSVGFGGEESA
GASFLRHNGQVWSTDKDGIIADLLASEIKATTGKSPSERYKELAEELGAPQYKRIDAPANREQKERLKKLSASDVEATEL
AGEKIEAILTEAPGNGAAIGGVKVTTENAWFAARPSGTEDKYKIYAESFNGAEHLDKVLEEAQVVVDGVLG

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786904, Length=555, Percent_Identity=56.5765765765766, Blast_Score=598, Evalue=1e-172,
Organism=Saccharomyces cerevisiae, GI6322722, Length=501, Percent_Identity=25.9481037924152, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323752, Length=345, Percent_Identity=25.7971014492754, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17864244, Length=423, Percent_Identity=26.9503546099291, Blast_Score=99, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 58408; Mature: 58408

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPRAGQPATPDDLTDIPALLEAYSATVPNLADPGQRVSFGTSGHRGSAFDGAFNEAHIL
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEE
ATTQAIVDYRREQGINGPIFIGRDPHALSEPAEATALEVLAGNRVNVMVDQERGFVPTPS
EHHHHHHHHHHHCCCCCCEEECCCCHHHCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCC
ISFAILEYNKQLPGGPEGTDAGRADGIVVTPSHNPPRDGGFKYNPPTGGPADTDATSWIA
CEEEEEEECCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHH
RRANEYLDADLSGVQRSTSTELVENHNYLGNYVAALPEVIDIEAVRSAGVRIGADPMGGA
HHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCC
SVAYWERIADVHGLDLTVVNPTIDPAFGFMTLDSDGKIRMDCSSPSAMASLVDAVAGAGG
HHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHCCCC
ASYDIATGNDADSDRHGIVTPDAGLMNPNHYLAVAIEYLFSHRENWPQDAAVGKTLVSSS
CCEEECCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
MIDRVVARMGRKLMEVPVGFKWFVPGLVNGSVGFGGEESAGASFLRHNGQVWSTDKDGII
HHHHHHHHHHHHHHHCCCCCEEECCHHCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCHH
ADLLASEIKATTGKSPSERYKELAEELGAPQYKRIDAPANREQKERLKKLSASDVEATEL
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCCHHHHH
AGEKIEAILTEAPGNGAAIGGVKVTTENAWFAARPSGTEDKYKIYAESFNGAEHLDKVLE
HHHHHHHHHEECCCCCEEECCEEEEECCCEEEECCCCCCCCEEEEEECCCCHHHHHHHHH
EAQVVVDGVLG
HHHHHHHHCCC
>Mature Secondary Structure
MHPRAGQPATPDDLTDIPALLEAYSATVPNLADPGQRVSFGTSGHRGSAFDGAFNEAHIL
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEE
ATTQAIVDYRREQGINGPIFIGRDPHALSEPAEATALEVLAGNRVNVMVDQERGFVPTPS
EHHHHHHHHHHHCCCCCCEEECCCCHHHCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCC
ISFAILEYNKQLPGGPEGTDAGRADGIVVTPSHNPPRDGGFKYNPPTGGPADTDATSWIA
CEEEEEEECCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHH
RRANEYLDADLSGVQRSTSTELVENHNYLGNYVAALPEVIDIEAVRSAGVRIGADPMGGA
HHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCC
SVAYWERIADVHGLDLTVVNPTIDPAFGFMTLDSDGKIRMDCSSPSAMASLVDAVAGAGG
HHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHCCCC
ASYDIATGNDADSDRHGIVTPDAGLMNPNHYLAVAIEYLFSHRENWPQDAAVGKTLVSSS
CCEEECCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
MIDRVVARMGRKLMEVPVGFKWFVPGLVNGSVGFGGEESAGASFLRHNGQVWSTDKDGII
HHHHHHHHHHHHHHHCCCCCEEECCHHCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCHH
ADLLASEIKATTGKSPSERYKELAEELGAPQYKRIDAPANREQKERLKKLSASDVEATEL
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCCHHHHH
AGEKIEAILTEAPGNGAAIGGVKVTTENAWFAARPSGTEDKYKIYAESFNGAEHLDKVLE
HHHHHHHHHEECCCCCEEECCEEEEECCCEEEECCCCCCCCEEEEEECCCCHHHHHHHHH
EAQVVVDGVLG
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8025683 [H]