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The map label for this gene is pbp2C [H]

Identifier: 68535482

GI number: 68535482

Start: 494353

End: 496134

Strand: Direct

Name: pbp2C [H]

Synonym: jk0412

Alternate gene names: 68535482

Gene position: 494353-496134 (Clockwise)

Preceding gene: 68535481

Following gene: 68535485

Centisome position: 20.08

GC content: 50.56

Gene sequence:

>1782_bases
ATGATGACTAAGCACAATCGTTTCCGTCAGTCGGTGATTGCACTCTGTTCGCTCTCCGCAGTGATGTTGAGCAGCTGTTC
AGCTCTACCGTGGGAATCAGACTCAGACGTATTTCTCAAAGCTTTCAACGCGGGAGATGACAGCAAGGCTGCACGGTATC
TGGATCATCCAGACCCGGAGCGCGCCCTTCATGAATTTCGGCAGTCACTACATGGTGTGAAGGTCAACATCGAAAAATCT
GATATTTCCAATGGAAAGCAGAATACTCATGTGACTTGGTCCAAAGATGGTGTGGAGTTGGAGAGCAATGGTCGGCTCGT
CCTTAGTGGACAGGATGGTAAGCCTCAATGGTTGCCTTCGATCTTCGAAGCTCAGTTGAGCGATGATTCCGCACTCTTTT
TTGCTGAAGATAAACAGTACGATCTTCCAATTAAAGATCGCTTGGGCAATGAATATATGACCTGGACGAAAGTTATTCAG
GTACGAGGTCGCAAAGACATAGCCTCTAGAGCGCAGGAATTGGCCCAGATTTTTGCACCAGTGTCTCCCACAACGACTAA
GGAGTGGATCGAGCAGACCTTGGGAGAGTCTCAGGATGAAGACACCGTGCTCCTCACTTTGAGGCAGGAAGAATTCCGGA
AGATACAAGAGCAACTTAGGACCTTTGAGGGAATTTCCACTGTGGAGCAGGGGCGTCTCTTAAGCGTGTCCAAAACTCTT
AACTCTCCGCTGGATGCTGAATTGAACAAATATTGGGAGTCAGTGCTCGATGCTAATTCAGGATGGTCGATACGCGCTGA
GAGTTCACAAGGTATGACGACGGTAGCCTCTGAGCCGCCTCGCCGAGTTCAGCCAATCGCAACCACTCTGGATAACACAC
TGCAAAGCGCAGCAAAACAAGCAGTGGACAGTGAGCAACGTGCCGCAGTTCTAGTCGTGCTCAATCCTAGAACAGGAGGT
GTCCTTGCCGTTGCACAAAATGACAAGGCAAATAACCAAGGGCCAATCGCACTCACCGGGCTATTCCCACCGGGATCGAC
GTTCAAAACTGTGACCACAGCGGCGGCACTAGAGGCAGGGGTAGTCAGCATGGATGAGGAACTACCTTGTCCTAGCAATA
TCACCGTCGCTGGACGCAAGATTCCCAACGATCATGACTTCGATCTAGGTAGCGTTCGACTGGAAGAAGCTTTCGCCCAA
TCATGTAACACAACCCAAGCGGTCATTTCGGATCGTTTGGGAGAAGATGATCTGCAACGGACTGCTTTAGAACTCGGAAT
TGGCTCCGACTTCGACGTACCAGGGATGACCACACTTACTGGTTCGGTGCCGCGGACACCGGCTGGACCTCCTCGTGTGG
AGGCTTCTATTGGACAGGGCGAGGTTCTAGCTAGTCCATTTGGGATTGCGCTCATGCAATCGACTGTCGCTAACGGCGGC
TTGCTTGTTCCTCCACAGCTCATTCAAGGCGAACAGACAGTAGTGAATAAACAGGCAGACCAGCATGTCAGCGATACAAC
TATTCAAAGCCTCCGGACGATGATGAAATCAACAATTGACCACGGTTCAGCTAGGTCGTTGAGTGATCTTAGTGCACTTG
GCGGAAAGACTGGTACAGCAGAAATTGATGGCAAGCTTTCCAATGGCTGGTTCGCTGGAACGACAGGGGAATTGGCGATT
GCGTCCCTTGTAATCGAAGGAGATTCTTCTCAGCCAGCTGTGGAAATGGCCGGGCGTTTCCTTCGCTCGCCGGATGTTCA
GAAATTCTCTGGAATTCAATAA

Upstream 100 bases:

>100_bases
TGAATACACACTTCTACCATCGCCTATATGTGAATGAAATGAGACAATTGCATTATGTGATATTGGTGGCATCCAATGCG
TCTCACTTAACGTCACTCCC

Downstream 100 bases:

>100_bases
ACTTGCGTCATAACCTCTAGCACGGCACGTCCACCGCAGCGATGCGGTGGGGTTGGATCGTGAGGCTCTCCCCGGTGGAT
TCGAGCACCGCGGAGATGGT

Product: putative penicillin-binding protein 2

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 593; Mature: 593

Protein sequence:

>593_residues
MMTKHNRFRQSVIALCSLSAVMLSSCSALPWESDSDVFLKAFNAGDDSKAARYLDHPDPERALHEFRQSLHGVKVNIEKS
DISNGKQNTHVTWSKDGVELESNGRLVLSGQDGKPQWLPSIFEAQLSDDSALFFAEDKQYDLPIKDRLGNEYMTWTKVIQ
VRGRKDIASRAQELAQIFAPVSPTTTKEWIEQTLGESQDEDTVLLTLRQEEFRKIQEQLRTFEGISTVEQGRLLSVSKTL
NSPLDAELNKYWESVLDANSGWSIRAESSQGMTTVASEPPRRVQPIATTLDNTLQSAAKQAVDSEQRAAVLVVLNPRTGG
VLAVAQNDKANNQGPIALTGLFPPGSTFKTVTTAAALEAGVVSMDEELPCPSNITVAGRKIPNDHDFDLGSVRLEEAFAQ
SCNTTQAVISDRLGEDDLQRTALELGIGSDFDVPGMTTLTGSVPRTPAGPPRVEASIGQGEVLASPFGIALMQSTVANGG
LLVPPQLIQGEQTVVNKQADQHVSDTTIQSLRTMMKSTIDHGSARSLSDLSALGGKTGTAEIDGKLSNGWFAGTTGELAI
ASLVIEGDSSQPAVEMAGRFLRSPDVQKFSGIQ

Sequences:

>Translated_593_residues
MMTKHNRFRQSVIALCSLSAVMLSSCSALPWESDSDVFLKAFNAGDDSKAARYLDHPDPERALHEFRQSLHGVKVNIEKS
DISNGKQNTHVTWSKDGVELESNGRLVLSGQDGKPQWLPSIFEAQLSDDSALFFAEDKQYDLPIKDRLGNEYMTWTKVIQ
VRGRKDIASRAQELAQIFAPVSPTTTKEWIEQTLGESQDEDTVLLTLRQEEFRKIQEQLRTFEGISTVEQGRLLSVSKTL
NSPLDAELNKYWESVLDANSGWSIRAESSQGMTTVASEPPRRVQPIATTLDNTLQSAAKQAVDSEQRAAVLVVLNPRTGG
VLAVAQNDKANNQGPIALTGLFPPGSTFKTVTTAAALEAGVVSMDEELPCPSNITVAGRKIPNDHDFDLGSVRLEEAFAQ
SCNTTQAVISDRLGEDDLQRTALELGIGSDFDVPGMTTLTGSVPRTPAGPPRVEASIGQGEVLASPFGIALMQSTVANGG
LLVPPQLIQGEQTVVNKQADQHVSDTTIQSLRTMMKSTIDHGSARSLSDLSALGGKTGTAEIDGKLSNGWFAGTTGELAI
ASLVIEGDSSQPAVEMAGRFLRSPDVQKFSGIQ
>Mature_593_residues
MMTKHNRFRQSVIALCSLSAVMLSSCSALPWESDSDVFLKAFNAGDDSKAARYLDHPDPERALHEFRQSLHGVKVNIEKS
DISNGKQNTHVTWSKDGVELESNGRLVLSGQDGKPQWLPSIFEAQLSDDSALFFAEDKQYDLPIKDRLGNEYMTWTKVIQ
VRGRKDIASRAQELAQIFAPVSPTTTKEWIEQTLGESQDEDTVLLTLRQEEFRKIQEQLRTFEGISTVEQGRLLSVSKTL
NSPLDAELNKYWESVLDANSGWSIRAESSQGMTTVASEPPRRVQPIATTLDNTLQSAAKQAVDSEQRAAVLVVLNPRTGG
VLAVAQNDKANNQGPIALTGLFPPGSTFKTVTTAAALEAGVVSMDEELPCPSNITVAGRKIPNDHDFDLGSVRLEEAFAQ
SCNTTQAVISDRLGEDDLQRTALELGIGSDFDVPGMTTLTGSVPRTPAGPPRVEASIGQGEVLASPFGIALMQSTVANGG
LLVPPQLIQGEQTVVNKQADQHVSDTTIQSLRTMMKSTIDHGSARSLSDLSALGGKTGTAEIDGKLSNGWFAGTTGELAI
ASLVIEGDSSQPAVEMAGRFLRSPDVQKFSGIQ

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 64021; Mature: 64021

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTKHNRFRQSVIALCSLSAVMLSSCSALPWESDSDVFLKAFNAGDDSKAARYLDHPDPE
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCCCCHH
RALHEFRQSLHGVKVNIEKSDISNGKQNTHVTWSKDGVELESNGRLVLSGQDGKPQWLPS
HHHHHHHHHHCCEEEEEEHHHCCCCCCCCEEEECCCCEEEECCCEEEEECCCCCCCHHHH
IFEAQLSDDSALFFAEDKQYDLPIKDRLGNEYMTWTKVIQVRGRKDIASRAQELAQIFAP
HHHHHCCCCCEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
VSPTTTKEWIEQTLGESQDEDTVLLTLRQEEFRKIQEQLRTFEGISTVEQGRLLSVSKTL
CCCCCHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCHHHHCCCEEEEHHHH
NSPLDAELNKYWESVLDANSGWSIRAESSQGMTTVASEPPRRVQPIATTLDNTLQSAAKQ
CCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHH
AVDSEQRAAVLVVLNPRTGGVLAVAQNDKANNQGPIALTGLFPPGSTFKTVTTAAALEAG
HHCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHC
VVSMDEELPCPSNITVAGRKIPNDHDFDLGSVRLEEAFAQSCNTTQAVISDRLGEDDLQR
CEECCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCHHHHHH
TALELGIGSDFDVPGMTTLTGSVPRTPAGPPRVEASIGQGEVLASPFGIALMQSTVANGG
HHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCEECCCCCCCEECCCHHHHHHHHHHCCCC
LLVPPQLIQGEQTVVNKQADQHVSDTTIQSLRTMMKSTIDHGSARSLSDLSALGGKTGTA
EECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCE
EIDGKLSNGWFAGTTGELAIASLVIEGDSSQPAVEMAGRFLRSPDVQKFSGIQ
EECCEECCCEECCCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCCCHHHCCCC
>Mature Secondary Structure
MMTKHNRFRQSVIALCSLSAVMLSSCSALPWESDSDVFLKAFNAGDDSKAARYLDHPDPE
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCCCCHH
RALHEFRQSLHGVKVNIEKSDISNGKQNTHVTWSKDGVELESNGRLVLSGQDGKPQWLPS
HHHHHHHHHHCCEEEEEEHHHCCCCCCCCEEEECCCCEEEECCCEEEEECCCCCCCHHHH
IFEAQLSDDSALFFAEDKQYDLPIKDRLGNEYMTWTKVIQVRGRKDIASRAQELAQIFAP
HHHHHCCCCCEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
VSPTTTKEWIEQTLGESQDEDTVLLTLRQEEFRKIQEQLRTFEGISTVEQGRLLSVSKTL
CCCCCHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCHHHHCCCEEEEHHHH
NSPLDAELNKYWESVLDANSGWSIRAESSQGMTTVASEPPRRVQPIATTLDNTLQSAAKQ
CCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHH
AVDSEQRAAVLVVLNPRTGGVLAVAQNDKANNQGPIALTGLFPPGSTFKTVTTAAALEAG
HHCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHC
VVSMDEELPCPSNITVAGRKIPNDHDFDLGSVRLEEAFAQSCNTTQAVISDRLGEDDLQR
CEECCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCHHHHHH
TALELGIGSDFDVPGMTTLTGSVPRTPAGPPRVEASIGQGEVLASPFGIALMQSTVANGG
HHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCEECCCCCCCEECCCHHHHHHHHHHCCCC
LLVPPQLIQGEQTVVNKQADQHVSDTTIQSLRTMMKSTIDHGSARSLSDLSALGGKTGTA
EECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCE
EIDGKLSNGWFAGTTGELAIASLVIEGDSSQPAVEMAGRFLRSPDVQKFSGIQ
EECCEECCCEECCCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]