BacMap

Definition	Corynebacterium jeikeium K411, complete genome.
Accession	NC_007164
Length	2,462,499

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The map label for this gene is echA1 [H]

Identifier: 68535463

GI number: 68535463

Start: 468240

End: 469037

Strand: Direct

Name: echA1 [H]

Synonym: jk0395

Alternate gene names: 68535463

Gene position: 468240-469037 (Clockwise)

Preceding gene: 68535459

Following gene: 68535464

Centisome position: 19.01

GC content: 59.77

Gene sequence:

>798_bases
ATGGCAAGCATGACTACCGAAAACCAGACTTATGAAAACATCAAGGTGGCTGTTCAAGGTGCCGTTGCGACCATCACCCT
GGACCGTCCGAAGGCTCTTAACGCACTGAACAGCGCAGTCCTTTCTGAGATTATTCCGGCAGCGGAGGCGTTGGATGCGG
ATCCTCAGGTCGGTGCCATCGTCATTACCGGCAGTGAAAAGGCTTTCGCCGCTGGCGCGGATATCAAGGAAATGAAGGAT
GAAACCTACCCAGAGGTGGCAGAAAAGCGTCTGTTCGGCGATTGGGAGAAACTGGCGCAACTGAAGACCCCGCTGATCAC
CGCTGTATCCGGTTTTGCCTTGGGTGGCGGCTGCGAGCTGGCGATGCTCGGCGATATTCTGTTGGCCAGTGAGTCTGCAA
AGTTTGGCCAGCCGGAGATCACACTGGGCATCATCCCGGGAATGGGTGGTACCCAACGCCTGACCCGCGCAGTGGGGAAG
TACAAAGCGATGGACCTGATCCTCACAGGCCGCATGATGGATGCCGAGGAGGCTGAGCGCAGCGGCCTAGTATCCCGTGT
GCTCCCGGCAGAGGGGTTCGCTGAGGAGGTGCAGAAGGTAGCAGCCAAGGTGGCAAGCATGTCCCATGTTGCAACGGCTG
CCGCGACGGAGATGGTGGACGAGGCCTACCGCTCCACTCTCGAGGAGGGCGTGGAGGCGGAGCGCCAGCAGTTCTGGCGC
CTCTTTGGCACCGCCGACCAGAAGGAAGGCATGGCCGCTTTCGTGGAGAAGCGCAAGCCGGAGTGGCAGCACCGCTAA

Upstream 100 bases:

>100_bases
TTTGAACTCGCTGTTTGCAGGCGCGTTTTGATTCTTAAAGACGCCCTTACGCCCCGAGCTTCGCCAGATTCTCAGGCACG
GCAGCAGGGGATTTGGTTCA

Downstream 100 bases:

>100_bases
CCGCGCCGCCAGGCATCATTCCTGGCACAATTGCGACTATGTCACATTCGAAGCAAGTCAACCGCACCATTGACCTGTCC
ATTCGCGACGTTTACGAAGT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MASMTTENQTYENIKVAVQGAVATITLDRPKALNALNSAVLSEIIPAAEALDADPQVGAIVITGSEKAFAAGADIKEMKD
ETYPEVAEKRLFGDWEKLAQLKTPLITAVSGFALGGGCELAMLGDILLASESAKFGQPEITLGIIPGMGGTQRLTRAVGK
YKAMDLILTGRMMDAEEAERSGLVSRVLPAEGFAEEVQKVAAKVASMSHVATAAATEMVDEAYRSTLEEGVEAERQQFWR
LFGTADQKEGMAAFVEKRKPEWQHR

Sequences:

>Translated_265_residues
MASMTTENQTYENIKVAVQGAVATITLDRPKALNALNSAVLSEIIPAAEALDADPQVGAIVITGSEKAFAAGADIKEMKD
ETYPEVAEKRLFGDWEKLAQLKTPLITAVSGFALGGGCELAMLGDILLASESAKFGQPEITLGIIPGMGGTQRLTRAVGK
YKAMDLILTGRMMDAEEAERSGLVSRVLPAEGFAEEVQKVAAKVASMSHVATAAATEMVDEAYRSTLEEGVEAERQQFWR
LFGTADQKEGMAAFVEKRKPEWQHR
>Mature_264_residues
ASMTTENQTYENIKVAVQGAVATITLDRPKALNALNSAVLSEIIPAAEALDADPQVGAIVITGSEKAFAAGADIKEMKDE
TYPEVAEKRLFGDWEKLAQLKTPLITAVSGFALGGGCELAMLGDILLASESAKFGQPEITLGIIPGMGGTQRLTRAVGKY
KAMDLILTGRMMDAEEAERSGLVSRVLPAEGFAEEVQKVAAKVASMSHVATAAATEMVDEAYRSTLEEGVEAERQQFWRL
FGTADQKEGMAAFVEKRKPEWQHR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=244, Percent_Identity=50.4098360655738, Blast_Score=254, Evalue=4e-68,
Organism=Homo sapiens, GI31542718, Length=251, Percent_Identity=29.0836653386454, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI4502327, Length=249, Percent_Identity=34.9397590361446, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI68989263, Length=188, Percent_Identity=34.5744680851064, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI20127408, Length=189, Percent_Identity=33.8624338624339, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI70995211, Length=197, Percent_Identity=30.4568527918782, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI150378541, Length=248, Percent_Identity=30.241935483871, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI37594471, Length=217, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI37594469, Length=217, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI25453481, Length=266, Percent_Identity=26.3157894736842, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI51538573, Length=266, Percent_Identity=26.3157894736842, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI4757968, Length=260, Percent_Identity=25.7692307692308, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI49355787, Length=260, Percent_Identity=25.7692307692308, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI221307494, Length=261, Percent_Identity=27.2030651340996, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI221136756, Length=261, Percent_Identity=27.2030651340996, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI221136753, Length=261, Percent_Identity=27.2030651340996, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI4757966, Length=255, Percent_Identity=26.2745098039216, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI51538581, Length=255, Percent_Identity=26.2745098039216, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI260274832, Length=236, Percent_Identity=27.9661016949153, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI45643119, Length=236, Percent_Identity=27.9661016949153, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI260275230, Length=236, Percent_Identity=27.9661016949153, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI116235487, Length=233, Percent_Identity=26.6094420600858, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI213417737, Length=171, Percent_Identity=26.3157894736842, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI157694516, Length=238, Percent_Identity=24.3697478991597, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI261878539, Length=93, Percent_Identity=40.8602150537634, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI62530384, Length=245, Percent_Identity=24.0816326530612, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1787659, Length=258, Percent_Identity=42.2480620155039, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI221142681, Length=264, Percent_Identity=34.0909090909091, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1787660, Length=258, Percent_Identity=33.3333333333333, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1790281, Length=190, Percent_Identity=32.6315789473684, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI87082183, Length=262, Percent_Identity=27.0992366412214, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1788597, Length=249, Percent_Identity=28.9156626506024, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788682, Length=210, Percent_Identity=31.9047619047619, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17554946, Length=251, Percent_Identity=50.597609561753, Blast_Score=253, Evalue=9e-68,
Organism=Caenorhabditis elegans, GI25145438, Length=241, Percent_Identity=46.8879668049792, Blast_Score=226, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17560910, Length=259, Percent_Identity=32.4324324324324, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17540714, Length=226, Percent_Identity=30.5309734513274, Blast_Score=111, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17540306, Length=243, Percent_Identity=31.6872427983539, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17558304, Length=185, Percent_Identity=35.6756756756757, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI25144157, Length=223, Percent_Identity=30.4932735426009, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI25144160, Length=223, Percent_Identity=30.4932735426009, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI25144276, Length=228, Percent_Identity=30.7017543859649, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17508953, Length=228, Percent_Identity=30.7017543859649, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17508951, Length=228, Percent_Identity=30.7017543859649, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17536985, Length=230, Percent_Identity=28.2608695652174, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17534483, Length=275, Percent_Identity=25.4545454545455, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17549921, Length=238, Percent_Identity=26.4705882352941, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17535521, Length=258, Percent_Identity=23.6434108527132, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25141363, Length=199, Percent_Identity=27.6381909547739, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320241, Length=193, Percent_Identity=27.4611398963731, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI20129971, Length=265, Percent_Identity=50.188679245283, Blast_Score=267, Evalue=5e-72,
Organism=Drosophila melanogaster, GI24653477, Length=265, Percent_Identity=50.188679245283, Blast_Score=267, Evalue=5e-72,
Organism=Drosophila melanogaster, GI24653139, Length=259, Percent_Identity=35.1351351351351, Blast_Score=124, Evalue=7e-29,
Organism=Drosophila melanogaster, GI19922422, Length=263, Percent_Identity=25.4752851711027, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21357171, Length=264, Percent_Identity=28.030303030303, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI19920382, Length=227, Percent_Identity=31.7180616740088, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24650670, Length=170, Percent_Identity=31.1764705882353, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI28571730, Length=250, Percent_Identity=26.4, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571729, Length=250, Percent_Identity=26.4, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19921000, Length=211, Percent_Identity=33.175355450237, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24583077, Length=211, Percent_Identity=33.175355450237, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24583079, Length=211, Percent_Identity=33.175355450237, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24654903, Length=258, Percent_Identity=22.4806201550388, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583165, Length=252, Percent_Identity=23.4126984126984, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28452; Mature: 28321

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASMTTENQTYENIKVAVQGAVATITLDRPKALNALNSAVLSEIIPAAEALDADPQVGAI
CCCCCCCCCHHHHHHEEEECEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
VITGSEKAFAAGADIKEMKDETYPEVAEKRLFGDWEKLAQLKTPLITAVSGFALGGGCEL
EEECCCCCEECCCCHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHH
AMLGDILLASESAKFGQPEITLGIIPGMGGTQRLTRAVGKYKAMDLILTGRMMDAEEAER
HHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHEECCCCCHHHHHH
SGLVSRVLPAEGFAEEVQKVAAKVASMSHVATAAATEMVDEAYRSTLEEGVEAERQQFWR
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFGTADQKEGMAAFVEKRKPEWQHR
HHCCCCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ASMTTENQTYENIKVAVQGAVATITLDRPKALNALNSAVLSEIIPAAEALDADPQVGAI
CCCCCCCCHHHHHHEEEECEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
VITGSEKAFAAGADIKEMKDETYPEVAEKRLFGDWEKLAQLKTPLITAVSGFALGGGCEL
EEECCCCCEECCCCHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHH
AMLGDILLASESAKFGQPEITLGIIPGMGGTQRLTRAVGKYKAMDLILTGRMMDAEEAER
HHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHEECCCCCHHHHHH
SGLVSRVLPAEGFAEEVQKVAAKVASMSHVATAAATEMVDEAYRSTLEEGVEAERQQFWR
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFGTADQKEGMAAFVEKRKPEWQHR
HHCCCCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]