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The map label for this gene is uppP2

Identifier: 68535432

GI number: 68535432

Start: 440379

End: 441224

Strand: Direct

Name: uppP2

Synonym: jk0367

Alternate gene names: 68535432

Gene position: 440379-441224 (Clockwise)

Preceding gene: 68535429

Following gene: 68535433

Centisome position: 17.88

GC content: 63.48

Gene sequence:

>846_bases
ATGACTGATCCCGCCACCACAATGTCCTGGGTCCAGGTGATCGTCCTGTCTGTTGTCCAGGGCCTCACCGAGTTTCTGCC
AGTGTCTTCCTCGGGCCACCTGCGCATCGTCTCCCAACTGTTTTGGGGCGAAGACGCCGGCGCCAGCTTCACCGCCGTGA
TCCAGCTGGGAACGGAGCTTGCCGTGCTGGTCTTCTTTGCCAAAGACATCTGGCGCATTCTCACCGCCTGGTTCGCCGGC
CTCGCGGACAAATCCAAGCGGAACTTCGACTACCGCATGGGCTGGATGGTCATCGCCGGCACCATCCCGGTCGGTCTTGC
AGGCGTGCTGCTCAAGGACTTAATCCGCGAGAACTTCCGCAACCTCTGGATCACCGCCACCGTGCTAATCCTGTTCTCGC
TGGTGTTCATCCTGGCCGAGCGCCGCGGCAAGAAGACCCGCGGCTTCGAGGAACTGACCATGAAGGACGCGGTTCTGATG
GGCCTGTGGCAGTGCCTGGCGCTCATCCCCGGTGTGTCGCGCTCCGGCGGCACCATTTCCGGCGGTCTGTTCCTCAACCT
CGACCGCGAGGTTGCCACCCGTTTCTCCTTCCTGCTAGCCATTCCGGCAGTGCTGGCCTCCGGGCTGTTCTCCCTGCCTG
ATGCCTTCGACCCCCAGGCGGGCCAGGCGGCGAGCGGTTTGCAGCTGCTCGTCGGCTCCGGCATCGGCTTTGTGGTCGGC
TACATCTCCATTGCGTGGCTGCTGAAGTTCGTGTCCAACCACTCGTTCGCGTGGTTCGCCGCCTACCGCATTCCGCTGGG
CCTTTTGGTCATGGCGCTGCTCGGCACTGGCGTGATGGCCGCCTAG

Upstream 100 bases:

>100_bases
GGAACTGGGGGCAAACAAACGAGCATTCACAAGGTTAAAGCCTAGCAACGCGCCCGTCGCGTACCGCGATGGCTAAGCGG
GCGGGGTAGTGTCTTTCGCC

Downstream 100 bases:

>100_bases
TTGTAGGGTTGTCCGCATGCATGCATGGCCCGACCCGTCCGTACCCGTAGTCGCCGGCACCCCGGTGCCGCTGAAGCTCT
TCGACACCGCCGATCAGCGC

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein 1; Undecaprenyl pyrophosphate phosphatase 1

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MTDPATTMSWVQVIVLSVVQGLTEFLPVSSSGHLRIVSQLFWGEDAGASFTAVIQLGTELAVLVFFAKDIWRILTAWFAG
LADKSKRNFDYRMGWMVIAGTIPVGLAGVLLKDLIRENFRNLWITATVLILFSLVFILAERRGKKTRGFEELTMKDAVLM
GLWQCLALIPGVSRSGGTISGGLFLNLDREVATRFSFLLAIPAVLASGLFSLPDAFDPQAGQAASGLQLLVGSGIGFVVG
YISIAWLLKFVSNHSFAWFAAYRIPLGLLVMALLGTGVMAA

Sequences:

>Translated_281_residues
MTDPATTMSWVQVIVLSVVQGLTEFLPVSSSGHLRIVSQLFWGEDAGASFTAVIQLGTELAVLVFFAKDIWRILTAWFAG
LADKSKRNFDYRMGWMVIAGTIPVGLAGVLLKDLIRENFRNLWITATVLILFSLVFILAERRGKKTRGFEELTMKDAVLM
GLWQCLALIPGVSRSGGTISGGLFLNLDREVATRFSFLLAIPAVLASGLFSLPDAFDPQAGQAASGLQLLVGSGIGFVVG
YISIAWLLKFVSNHSFAWFAAYRIPLGLLVMALLGTGVMAA
>Mature_280_residues
TDPATTMSWVQVIVLSVVQGLTEFLPVSSSGHLRIVSQLFWGEDAGASFTAVIQLGTELAVLVFFAKDIWRILTAWFAGL
ADKSKRNFDYRMGWMVIAGTIPVGLAGVLLKDLIRENFRNLWITATVLILFSLVFILAERRGKKTRGFEELTMKDAVLMG
LWQCLALIPGVSRSGGTISGGLFLNLDREVATRFSFLLAIPAVLASGLFSLPDAFDPQAGQAASGLQLLVGSGIGFVVGY
ISIAWLLKFVSNHSFAWFAAYRIPLGLLVMALLGTGVMAA

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=255, Percent_Identity=36.8627450980392, Blast_Score=131, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP1_CORJK (Q4JXD8)

Other databases:

- EMBL:   CR931997
- RefSeq:   YP_250137.1
- STRING:   Q4JXD8
- GeneID:   3433526
- GenomeReviews:   CR931997_GR
- KEGG:   cjk:jk0367
- NMPDR:   fig|306537.3.peg.1468
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   KEIDWIF
- ProtClustDB:   PRK00281
- BioCyc:   CJEI306537:JK0367-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30422; Mature: 30291

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1577f204)-; HASH(0x16f0ad70)-; HASH(0x16f0abfc)-; HASH(0x165ed47c)-; HASH(0x16f08120)-; HASH(0x16f3e1cc)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPATTMSWVQVIVLSVVQGLTEFLPVSSSGHLRIVSQLFWGEDAGASFTAVIQLGTEL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
AVLVFFAKDIWRILTAWFAGLADKSKRNFDYRMGWMVIAGTIPVGLAGVLLKDLIRENFR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHEEEECHHHHHHHHHHHHHHHHHHHH
NLWITATVLILFSLVFILAERRGKKTRGFEELTMKDAVLMGLWQCLALIPGVSRSGGTIS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
GGLFLNLDREVATRFSFLLAIPAVLASGLFSLPDAFDPQAGQAASGLQLLVGSGIGFVVG
CCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCHHHHHHCCHHHHHH
YISIAWLLKFVSNHSFAWFAAYRIPLGLLVMALLGTGVMAA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure 
TDPATTMSWVQVIVLSVVQGLTEFLPVSSSGHLRIVSQLFWGEDAGASFTAVIQLGTEL
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
AVLVFFAKDIWRILTAWFAGLADKSKRNFDYRMGWMVIAGTIPVGLAGVLLKDLIRENFR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHEEEECHHHHHHHHHHHHHHHHHHHH
NLWITATVLILFSLVFILAERRGKKTRGFEELTMKDAVLMGLWQCLALIPGVSRSGGTIS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
GGLFLNLDREVATRFSFLLAIPAVLASGLFSLPDAFDPQAGQAASGLQLLVGSGIGFVVG
CCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCHHHHHHCCHHHHHH
YISIAWLLKFVSNHSFAWFAAYRIPLGLLVMALLGTGVMAA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA