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The map label for this gene is sglT [H]

Identifier: 68535353

GI number: 68535353

Start: 350874

End: 352529

Strand: Direct

Name: sglT [H]

Synonym: jk0288

Alternate gene names: 68535353

Gene position: 350874-352529 (Clockwise)

Preceding gene: 68535352

Following gene: 68535354

Centisome position: 14.25

GC content: 62.68

Gene sequence:

>1656_bases
ATGACAGCTGAAGGACTACGCCTGGACGCAAGCTGGGTAGACTACGCGCTGGTCGCCCTATACTTCGCGTTCGTCCTGGG
CATCGGTTGGGCCGCAAAGTCCAAAGTGTCCAGCTCAATCGACTTCTTCCTCTCCGGCCGCTCGCTACCCGCATGGGTGA
CGGGCCTGGCCTTCATCTCCGCCAACCTGGGCGCCGTAGAAATCGTGGGCCACTCGGCCAACGGCGTGCAGTACGGCTTC
GAAACCATGCACTATTTCTGGATCGGCGCGATCCCAGCAATGGTGTTCCTCGGCATCGTGATGATGCCTTTCTACTATGG
CTCCAAGGTGCGTTCCGTGCCGGAGTTCATGCTCCGCCGCTTCGGCAAGGGCGCACACCTGGTCAACGGCCTCTCCTTCG
CCGTAGCCCAGCTGCTGATTGCCGGCGTGAACCTGCTGCTGTTGGCCAAGGTGGTTAACTCCCTGCTCGGCTGGCCGCTG
TGGGTCACGCTGGTGGTGGCCGCGGCAATCGTGCTGTCGTACATCACCCTCGGTGGCCTTTCCGCCGCCATTTACAACGA
GGTGCTGCAGTTCTTCGTGATCATCGCGGCCCTGCTGCCGCTGACGATGATTGGCCTGCACCAAGTCGGCGGCTGGTCCG
GCCTGCAGGAGAAGGTCGCGGACCCGTCGCACTTCCACACCTGGCCGGGTACTGAAATCTCGGGCTTCGACAACCCGATC
GTCTCCGCCATCGGCCTGGTCTTCGGCCTGGGCTTCGTGCTGTCCTTCGGTTACTGGACCACCAACTTCGTGGAGGTGCA
GCGCTCCATGGCAGCCGATTCGCTGTCGTCTGCACGCAAGACCCCGATCATCGGTGCGTTCCCGAAGATGTTCATCCCGT
TCCTGGTGGTCATCCCGGGCATGGTTGCAGGTGCAACCGTCACCCCGATCATGGATGGTTCTGCCGAGCCGAACGACGCG
ATCCTGTACCTGATGCGTGACCTGCTGCCGAACGGCCTGCTGGGCGTGGCTATCGCGGGTCTGCTGGCCGCGTTCATGGC
CGGCATGGCGGCTAACATTTCCGCCTTCAACACCGTGTTCTCCTACGACATTTGGGAGTCCTACATCGTCAAGGATCGCG
ACGACGAGTACTACCTCAAGGTCGGCCGTATCGCGACCGTCGGCGCCACCGTCATTGCCGTGTTCACCGCCCTGCTGGCC
TCCAACTTCGGCAACATCATGGACTACCTGCAGACGCTGTTCGGCTTCTTCAACGCGCCGCTGTTCGCCACCTTCATCCT
GGGTATGTTCTGGAAGCGCATGACGCCCACCGCAGGTTGGGTGGGCCTCGTTTCCGGTACGGGTGTGGCAATCGTCTACT
GGGCTGTGGCCACCTTCGGCAGCACCGACGCAACGTTCTTCAACCTGCCGGGTCAGGGTACGGCCTTCGTTGCCGCCTCC
CTGGCGTTCGTCACGGACATCATCGCCTCCGTCCTGGTCTCCCTGGTCACCGAGCCGAAGCCGGACGAGGAGCTGGTGGG
CTTCGTCAAGTCCGTCACCCCGAAGGAAAACCTCACGGACGCCGCCGAGGCCACCCTGCCGTGGTACCGCCGCACCGTCC
CGCTGGGCATCCTCTGTCTGGCAATGGTGCTCGTCCTCAACATCGTGTTCGCCTAA

Upstream 100 bases:

>100_bases
GGTACCGCATATATATCCAATAGTTCCCGTCGCTGGTAATTGGAAAACATAACCGTTGGCGCCTGGGACGGGAACATGAC
GTTCCTGGAGGTTCGCAGCT

Downstream 100 bases:

>100_bases
GAGCGCTTAAACTTTCAGAAAGGAGTGAACGGACACAATGGCTAACAACACGGCTAAGAAAATCAAGCGTTCTCACATGG
CCGGTGCTTTCGACATCCGC

Product: putative sodium:solute symporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MTAEGLRLDASWVDYALVALYFAFVLGIGWAAKSKVSSSIDFFLSGRSLPAWVTGLAFISANLGAVEIVGHSANGVQYGF
ETMHYFWIGAIPAMVFLGIVMMPFYYGSKVRSVPEFMLRRFGKGAHLVNGLSFAVAQLLIAGVNLLLLAKVVNSLLGWPL
WVTLVVAAAIVLSYITLGGLSAAIYNEVLQFFVIIAALLPLTMIGLHQVGGWSGLQEKVADPSHFHTWPGTEISGFDNPI
VSAIGLVFGLGFVLSFGYWTTNFVEVQRSMAADSLSSARKTPIIGAFPKMFIPFLVVIPGMVAGATVTPIMDGSAEPNDA
ILYLMRDLLPNGLLGVAIAGLLAAFMAGMAANISAFNTVFSYDIWESYIVKDRDDEYYLKVGRIATVGATVIAVFTALLA
SNFGNIMDYLQTLFGFFNAPLFATFILGMFWKRMTPTAGWVGLVSGTGVAIVYWAVATFGSTDATFFNLPGQGTAFVAAS
LAFVTDIIASVLVSLVTEPKPDEELVGFVKSVTPKENLTDAAEATLPWYRRTVPLGILCLAMVLVLNIVFA

Sequences:

>Translated_551_residues
MTAEGLRLDASWVDYALVALYFAFVLGIGWAAKSKVSSSIDFFLSGRSLPAWVTGLAFISANLGAVEIVGHSANGVQYGF
ETMHYFWIGAIPAMVFLGIVMMPFYYGSKVRSVPEFMLRRFGKGAHLVNGLSFAVAQLLIAGVNLLLLAKVVNSLLGWPL
WVTLVVAAAIVLSYITLGGLSAAIYNEVLQFFVIIAALLPLTMIGLHQVGGWSGLQEKVADPSHFHTWPGTEISGFDNPI
VSAIGLVFGLGFVLSFGYWTTNFVEVQRSMAADSLSSARKTPIIGAFPKMFIPFLVVIPGMVAGATVTPIMDGSAEPNDA
ILYLMRDLLPNGLLGVAIAGLLAAFMAGMAANISAFNTVFSYDIWESYIVKDRDDEYYLKVGRIATVGATVIAVFTALLA
SNFGNIMDYLQTLFGFFNAPLFATFILGMFWKRMTPTAGWVGLVSGTGVAIVYWAVATFGSTDATFFNLPGQGTAFVAAS
LAFVTDIIASVLVSLVTEPKPDEELVGFVKSVTPKENLTDAAEATLPWYRRTVPLGILCLAMVLVLNIVFA
>Mature_550_residues
TAEGLRLDASWVDYALVALYFAFVLGIGWAAKSKVSSSIDFFLSGRSLPAWVTGLAFISANLGAVEIVGHSANGVQYGFE
TMHYFWIGAIPAMVFLGIVMMPFYYGSKVRSVPEFMLRRFGKGAHLVNGLSFAVAQLLIAGVNLLLLAKVVNSLLGWPLW
VTLVVAAAIVLSYITLGGLSAAIYNEVLQFFVIIAALLPLTMIGLHQVGGWSGLQEKVADPSHFHTWPGTEISGFDNPIV
SAIGLVFGLGFVLSFGYWTTNFVEVQRSMAADSLSSARKTPIIGAFPKMFIPFLVVIPGMVAGATVTPIMDGSAEPNDAI
LYLMRDLLPNGLLGVAIAGLLAAFMAGMAANISAFNTVFSYDIWESYIVKDRDDEYYLKVGRIATVGATVIAVFTALLAS
NFGNIMDYLQTLFGFFNAPLFATFILGMFWKRMTPTAGWVGLVSGTGVAIVYWAVATFGSTDATFFNLPGQGTAFVAASL
AFVTDIIASVLVSLVTEPKPDEELVGFVKSVTPKENLTDAAEATLPWYRRTVPLGILCLAMVLVLNIVFA

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG4146

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI206597483, Length=523, Percent_Identity=28.4894837476099, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI14140236, Length=574, Percent_Identity=24.390243902439, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI4507031, Length=551, Percent_Identity=26.8602540834846, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI206597487, Length=548, Percent_Identity=27.1897810218978, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI110835708, Length=562, Percent_Identity=27.9359430604982, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI109659836, Length=465, Percent_Identity=26.8817204301075, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI17941285, Length=454, Percent_Identity=28.4140969162996, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI4507033, Length=555, Percent_Identity=27.5675675675676, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI109659839, Length=480, Percent_Identity=26.25, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI256985183, Length=430, Percent_Identity=24.6511627906977, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI167466278, Length=452, Percent_Identity=23.8938053097345, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI4507035, Length=434, Percent_Identity=23.0414746543779, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI157671931, Length=455, Percent_Identity=22.8571428571429, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1790113, Length=429, Percent_Identity=25.6410256410256, Blast_Score=112, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI32566512, Length=355, Percent_Identity=23.943661971831, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI115533094, Length=443, Percent_Identity=20.9932279909707, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24645928, Length=501, Percent_Identity=24.1516966067864, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24641117, Length=514, Percent_Identity=23.3463035019455, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28573698, Length=447, Percent_Identity=21.2527964205817, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24651741, Length=448, Percent_Identity=20.7589285714286, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281362054, Length=465, Percent_Identity=24.3010752688172, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281362052, Length=465, Percent_Identity=24.3010752688172, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281362050, Length=465, Percent_Identity=24.3010752688172, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24648056, Length=465, Percent_Identity=24.3010752688172, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21356827, Length=465, Percent_Identity=24.3010752688172, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24651739, Length=512, Percent_Identity=20.8984375, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI221459584, Length=412, Percent_Identity=21.8446601941748, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281362918, Length=455, Percent_Identity=20.4395604395604, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24650192, Length=368, Percent_Identity=22.8260869565217, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221459586, Length=423, Percent_Identity=20.3309692671395, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221459588, Length=427, Percent_Identity=21.0772833723653, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 59156; Mature: 59025

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCC
>Mature Secondary Structure 
TAEGLRLDASWVDYALVALYFAFVLGIGWAAKSKVSSSIDFFLSGRSLPAWVTGLAFIS
CCCCCEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHH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HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]