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The map label for this gene is panC

Identifier: 68535351

GI number: 68535351

Start: 348797

End: 349717

Strand: Direct

Name: panC

Synonym: jk0286

Alternate gene names: 68535351

Gene position: 348797-349717 (Clockwise)

Preceding gene: 68535350

Following gene: 68535352

Centisome position: 14.16

GC content: 66.99

Gene sequence:

>921_bases
ATGACGTTCACACCTGGCCAAGCAGAGGTTTTTACCGAGATCGAGAAGATCGGGCAGCTCACCCGCGCCATGCGTAAGGC
GGGCCGCCCCGTGGCGCTGGTGCCCACGATGGGCGCGCTGCACGAGGGGCACCTCTCGCTGGTGCAGGCCGCCCAGCAGA
TTCCGGGTGCGCTGGTTGTGGTCAGCATTTTCGTGAACCCTCTGCAGTTCGCCGAGGGAGAGGACCTGGATGCCTACCCG
CGCACCCTCGACGAGGACGTCGCGAAGCTAAAGGCCGCGGGCGTGGACGCGGTATTCGCCCCCAGCCCCCGCGAGATGTA
CCCCAACGGGCCGCGCACGACTATCCACCCGGGCGAGGCCGGCCGCATTCTGGAGGGAGCCCACCGCCCGACCCACTTCG
CGGGCGTGCTGACGGTCGTGAACAAGCTCTTCACCATCACGCATTGCGATCACGCCTTCTTCGGGGAGAAGGACTATCAG
CAGCTGTTGCTGATCCAGCAAATTGTGACGGACCTGAACATGGAGGTACAGGTCCACGGCGTGCCGATCGTGCGCGAGGC
CGATGGTCTGGCGAAGTCCTCCCGCAACGTCTACCTTTCCGACGAGGAGCGCGAGCTTGCCCTCACCCTGTCCGCCGCCC
TGACCGCCGGCGCTTTCGTGGCCGAGCAGGGCCCTGCGGCGGTGCTGCAGACTGCCGGATCTATTCTGGACGCCGCCTCG
GGCATCGACGTCGACTATCTTGAGCTGCGCGGTACGGACCTTTCCGACACCCCGGAGGACGGCGAGGCCCGCCTGCTGGT
GGCGGCGCGCGTTGGGACCACGCGCCTGATCGACAATGTGGGCGTGCCCCTGGGCACCGGCTTCAAGGGGTTGGATGACG
GCGGCGAAGGCAGCGCACCTGCCGACAACGCTGGCGAGTAG

Upstream 100 bases:

>100_bases
CAGGCGCAGCCGAGGCCGCCTACACCGCGATGGCTCGCCGCACCGCACTTAAAGCGGGGGCTATTGAGGTCGAAAGACTG
CTGGATCTAGAGTAATAGCC

Downstream 100 bases:

>100_bases
AGCTGAGCAGAACTGAGTAGAACCATGAGCGACGATCTAGACACCCTGCAGCGACACTCGCACCCCTTCGTGGATATTTC
AGCTGGGGAGTACCGCGCCA

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTFTPGQAEVFTEIEKIGQLTRAMRKAGRPVALVPTMGALHEGHLSLVQAAQQIPGALVVVSIFVNPLQFAEGEDLDAYP
RTLDEDVAKLKAAGVDAVFAPSPREMYPNGPRTTIHPGEAGRILEGAHRPTHFAGVLTVVNKLFTITHCDHAFFGEKDYQ
QLLLIQQIVTDLNMEVQVHGVPIVREADGLAKSSRNVYLSDEERELALTLSAALTAGAFVAEQGPAAVLQTAGSILDAAS
GIDVDYLELRGTDLSDTPEDGEARLLVAARVGTTRLIDNVGVPLGTGFKGLDDGGEGSAPADNAGE

Sequences:

>Translated_306_residues
MTFTPGQAEVFTEIEKIGQLTRAMRKAGRPVALVPTMGALHEGHLSLVQAAQQIPGALVVVSIFVNPLQFAEGEDLDAYP
RTLDEDVAKLKAAGVDAVFAPSPREMYPNGPRTTIHPGEAGRILEGAHRPTHFAGVLTVVNKLFTITHCDHAFFGEKDYQ
QLLLIQQIVTDLNMEVQVHGVPIVREADGLAKSSRNVYLSDEERELALTLSAALTAGAFVAEQGPAAVLQTAGSILDAAS
GIDVDYLELRGTDLSDTPEDGEARLLVAARVGTTRLIDNVGVPLGTGFKGLDDGGEGSAPADNAGE
>Mature_305_residues
TFTPGQAEVFTEIEKIGQLTRAMRKAGRPVALVPTMGALHEGHLSLVQAAQQIPGALVVVSIFVNPLQFAEGEDLDAYPR
TLDEDVAKLKAAGVDAVFAPSPREMYPNGPRTTIHPGEAGRILEGAHRPTHFAGVLTVVNKLFTITHCDHAFFGEKDYQQ
LLLIQQIVTDLNMEVQVHGVPIVREADGLAKSSRNVYLSDEERELALTLSAALTAGAFVAEQGPAAVLQTAGSILDAASG
IDVDYLELRGTDLSDTPEDGEARLLVAARVGTTRLIDNVGVPLGTGFKGLDDGGEGSAPADNAGE

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family

Homologues:

Organism=Escherichia coli, GI1786325, Length=275, Percent_Identity=46.9090909090909, Blast_Score=216, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6322046, Length=310, Percent_Identity=35.4838709677419, Blast_Score=162, Evalue=9e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PANC_CORJK (Q4JXL9)

Other databases:

- EMBL:   CR931997
- RefSeq:   YP_250056.1
- HSSP:   P0A5R0
- ProteinModelPortal:   Q4JXL9
- SMR:   Q4JXL9
- STRING:   Q4JXL9
- GeneID:   3432855
- GenomeReviews:   CR931997_GR
- KEGG:   cjk:jk0286
- NMPDR:   fig|306537.3.peg.955
- eggNOG:   COG0414
- HOGENOM:   HBG428839
- OMA:   EDFGSYP
- ProtClustDB:   PRK00380
- BioCyc:   CJEI306537:JK0286-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00158
- InterPro:   IPR003721
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR21299:SF1
- TIGRFAMs:   TIGR00018

Pfam domain/function: PF02569 Pantoate_ligase

EC number: =6.3.2.1

Molecular weight: Translated: 32368; Mature: 32237

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: ACT_SITE 44-44 BINDING 69-69 BINDING 69-69 BINDING 161-161 BINDING 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFTPGQAEVFTEIEKIGQLTRAMRKAGRPVALVPTMGALHEGHLSLVQAAQQIPGALVV
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCEEH
VSIFVNPLQFAEGEDLDAYPRTLDEDVAKLKAAGVDAVFAPSPREMYPNGPRTTIHPGEA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCHHHCCCCCCCEECCCCC
GRILEGAHRPTHFAGVLTVVNKLFTITHCDHAFFGEKDYQQLLLIQQIVTDLNMEVQVHG
CCHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHCCCCEEEECC
VPIVREADGLAKSSRNVYLSDEERELALTLSAALTAGAFVAEQGPAAVLQTAGSILDAAS
CEEEECCCCCHHCCCCEEECCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
GIDVDYLELRGTDLSDTPEDGEARLLVAARVGTTRLIDNVGVPLGTGFKGLDDGGEGSAP
CCCEEEEEEECCCCCCCCCCCCEEEEEEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCC
ADNAGE
CCCCCC
>Mature Secondary Structure 
TFTPGQAEVFTEIEKIGQLTRAMRKAGRPVALVPTMGALHEGHLSLVQAAQQIPGALVV
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCEEH
VSIFVNPLQFAEGEDLDAYPRTLDEDVAKLKAAGVDAVFAPSPREMYPNGPRTTIHPGEA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCHHHCCCCCCCEECCCCC
GRILEGAHRPTHFAGVLTVVNKLFTITHCDHAFFGEKDYQQLLLIQQIVTDLNMEVQVHG
CCHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHCCCCEEEECC
VPIVREADGLAKSSRNVYLSDEERELALTLSAALTAGAFVAEQGPAAVLQTAGSILDAAS
CEEEECCCCCHHCCCCEEECCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
GIDVDYLELRGTDLSDTPEDGEARLLVAARVGTTRLIDNVGVPLGTGFKGLDDGGEGSAP
CCCEEEEEEECCCCCCCCCCCCEEEEEEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCC
ADNAGE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA