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The map label for this gene is pkn1 [H]

Identifier: 77761168

GI number: 77761168

Start: 2200016

End: 2201632

Strand: Direct

Name: pkn1 [H]

Synonym: XC_1810

Alternate gene names: 77761168

Gene position: 2200016-2201632 (Clockwise)

Preceding gene: 66768129

Following gene: 66768132

Centisome position: 42.73

GC content: 69.76

Gene sequence:

>1617_bases
TTGAAGGAAGATCGCCTCTACCGCAGCGCCGACGATGCCATTCCGCTGTATCTGGCAATTCAGCAACGCAGCGAGGGCAA
GGATGCGGTCAGCCGACGTGGCCTGGAGCAGGCGCGGCGGCGTCTGCTTGAGCGCGGCCATGCGCTGGTCGAGCAGACCG
ACCGTCAGGACAACGCACTGGAGCAGGCGCGCGAACTGGCGATCGTGGCGCTGGCCCTGGCGCCGGAAGATCCCAAGGTG
CGCGCGCTGCAGCTCGAGGTGGAAACGGCCCAGCGCGTGCTCGGCTTCAATCGCGCCGGCGAGGACGATCTGCGCAACGG
GCGTCTGGGCGAAGACGGCAACGGCGCGCTGGTGAACTTCCGCGATGCCGCCCAGCTGGACCCGGACAACCCCCGCACAC
GCCAGGGCCTGGCCGCAGTGGAAAGCGCCTTGCTGCGGCGTGCCGAACAGGCCGCCGAGACGGCCAACTTCGTGGCGGCG
CGCTACTGGCTGCAGATGGCCGGCCAGGTGCGCGAGCGCGCCCCGACCATTGCCGATGCACGTGCGCGTATCGAGCGCAT
GCGGCGCGCGCAGATCGCCGCGCTGCGCGATGCCGGCCTGCGTGACCTGACCACCCCGCGCGGGCTCAAGCCGGCCGGCG
AGAAACTGGCCGAGGTGCTGCGCATTGCCGATCCCGGCGACCCGGTGGCCGGCGATTTGCGGCGGCGGCTGGAACTGGCC
ACGCACTACGGCAGTTTTCGTCCCGGCCAGGTGTTCACCGATGGCCTGAAGGTCGGTGGCCGCGGCCCGCAGATGATCGT
GGTGCCGCATGGTGCGTTCCGCATGGGCGCAGGCGACTACGAGCCGGGCGCATCGGACAACGAACGCCCGGCGCATTACG
TGCGCTTTGCGCGCGGGTTCGCGATGTCCATCACCGAAGTCACCTTGGCCGAATTCCGCCAATTCGTGGAAGCGACCAAG
GCGCGGCCGCGCGCAACCCGGCGCGGCCATTCGGTGGTCTACGACGAGCGCAGCGGCAACTTTATTCGCCGCAGCGGGGT
GGACTGGCAATCGGATTACAACGGCGCGCAGGCCGCCCCCAACAGCCCGGTGATGCACGTGAGCATCCGCGACGCCGAGG
CCTATGCGACGTGGCTGTCCGAACAGACCGGCCGCCACTACCACCTGCCCAGCGAAGCAGAGTTCGAATACGCGCTGCGT
GCCGGCACCACCGGCCGCTATCCGTGGGGTAACCCGGGCGTGCCGCCGCCTGATGCGGGCAACTTCACCGGCGGCAACGA
CGTCTCGCGCAGCGGGCGGCACTGGAACAACGGCTTTGTCGGCTATGGCGATGGCTTCTGGGGGCCGGCGCCGGTGGGCA
GTTTCCGCGTCAATGCTTGGGGCCTGCACGACATGGGCGGCAACCTGAGCGAGTGGGTGGCCGATTGCTGGCACGCCAGC
TACCGGCGCGCACCGGCCGACGGCGCCGCGTGGTTCAACCCCGGTTGCCGGCAGCGCCTGGTACGTGGTGGCAGCTGGGC
CAATTCGCCGCTGCAGACACGCGCGGCCTGGCGGCTGTCGCAAGAGTCCGACACCACCAGTGCGCGCATCGGCTTCCGCC
TGGCACGCGGCATCTAG

Upstream 100 bases:

>100_bases
TGGCGAAGAATCCGCCGAAACCGTTGCGCAATGGCAGCCACCACCGGTGGACCTCGGCGAGACGCCGCTGGCGCAAGTGC
GCCAGCGCGCTGCCGAGGCG

Downstream 100 bases:

>100_bases
GCCGGCGCGGCGGCAGGCTTAACCACGCAAAACGGCGCCACTGCATGGATGGAACCGGGCGCGGCCTGCGCCGGTCCAAG
CCGCAGCGTTTTCAAGGACC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MKEDRLYRSADDAIPLYLAIQQRSEGKDAVSRRGLEQARRRLLERGHALVEQTDRQDNALEQARELAIVALALAPEDPKV
RALQLEVETAQRVLGFNRAGEDDLRNGRLGEDGNGALVNFRDAAQLDPDNPRTRQGLAAVESALLRRAEQAAETANFVAA
RYWLQMAGQVRERAPTIADARARIERMRRAQIAALRDAGLRDLTTPRGLKPAGEKLAEVLRIADPGDPVAGDLRRRLELA
THYGSFRPGQVFTDGLKVGGRGPQMIVVPHGAFRMGAGDYEPGASDNERPAHYVRFARGFAMSITEVTLAEFRQFVEATK
ARPRATRRGHSVVYDERSGNFIRRSGVDWQSDYNGAQAAPNSPVMHVSIRDAEAYATWLSEQTGRHYHLPSEAEFEYALR
AGTTGRYPWGNPGVPPPDAGNFTGGNDVSRSGRHWNNGFVGYGDGFWGPAPVGSFRVNAWGLHDMGGNLSEWVADCWHAS
YRRAPADGAAWFNPGCRQRLVRGGSWANSPLQTRAAWRLSQESDTTSARIGFRLARGI

Sequences:

>Translated_538_residues
MKEDRLYRSADDAIPLYLAIQQRSEGKDAVSRRGLEQARRRLLERGHALVEQTDRQDNALEQARELAIVALALAPEDPKV
RALQLEVETAQRVLGFNRAGEDDLRNGRLGEDGNGALVNFRDAAQLDPDNPRTRQGLAAVESALLRRAEQAAETANFVAA
RYWLQMAGQVRERAPTIADARARIERMRRAQIAALRDAGLRDLTTPRGLKPAGEKLAEVLRIADPGDPVAGDLRRRLELA
THYGSFRPGQVFTDGLKVGGRGPQMIVVPHGAFRMGAGDYEPGASDNERPAHYVRFARGFAMSITEVTLAEFRQFVEATK
ARPRATRRGHSVVYDERSGNFIRRSGVDWQSDYNGAQAAPNSPVMHVSIRDAEAYATWLSEQTGRHYHLPSEAEFEYALR
AGTTGRYPWGNPGVPPPDAGNFTGGNDVSRSGRHWNNGFVGYGDGFWGPAPVGSFRVNAWGLHDMGGNLSEWVADCWHAS
YRRAPADGAAWFNPGCRQRLVRGGSWANSPLQTRAAWRLSQESDTTSARIGFRLARGI
>Mature_538_residues
MKEDRLYRSADDAIPLYLAIQQRSEGKDAVSRRGLEQARRRLLERGHALVEQTDRQDNALEQARELAIVALALAPEDPKV
RALQLEVETAQRVLGFNRAGEDDLRNGRLGEDGNGALVNFRDAAQLDPDNPRTRQGLAAVESALLRRAEQAAETANFVAA
RYWLQMAGQVRERAPTIADARARIERMRRAQIAALRDAGLRDLTTPRGLKPAGEKLAEVLRIADPGDPVAGDLRRRLELA
THYGSFRPGQVFTDGLKVGGRGPQMIVVPHGAFRMGAGDYEPGASDNERPAHYVRFARGFAMSITEVTLAEFRQFVEATK
ARPRATRRGHSVVYDERSGNFIRRSGVDWQSDYNGAQAAPNSPVMHVSIRDAEAYATWLSEQTGRHYHLPSEAEFEYALR
AGTTGRYPWGNPGVPPPDAGNFTGGNDVSRSGRHWNNGFVGYGDGFWGPAPVGSFRVNAWGLHDMGGNLSEWVADCWHAS
YRRAPADGAAWFNPGCRQRLVRGGSWANSPLQTRAAWRLSQESDTTSARIGFRLARGI

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=299, Percent_Identity=31.1036789297659, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI257470977, Length=295, Percent_Identity=30.8474576271186, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI194248087, Length=294, Percent_Identity=30.952380952381, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI257470975, Length=285, Percent_Identity=30.5263157894737, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI194248088, Length=309, Percent_Identity=30.7443365695793, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI226437577, Length=183, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI194248090, Length=223, Percent_Identity=31.390134529148, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI20130397, Length=303, Percent_Identity=29.7029702970297, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 59412; Mature: 59412

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEDRLYRSADDAIPLYLAIQQRSEGKDAVSRRGLEQARRRLLERGHALVEQTDRQDNAL
CCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHH
EQARELAIVALALAPEDPKVRALQLEVETAQRVLGFNRAGEDDLRNGRLGEDGNGALVNF
HHHHHHHHEEEEECCCCCCEEEEEEEHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCEEEE
RDAAQLDPDNPRTRQGLAAVESALLRRAEQAAETANFVAARYWLQMAGQVRERAPTIADA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
RARIERMRRAQIAALRDAGLRDLTTPRGLKPAGEKLAEVLRIADPGDPVAGDLRRRLELA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
THYGSFRPGQVFTDGLKVGGRGPQMIVVPHGAFRMGAGDYEPGASDNERPAHYVRFARGF
HHCCCCCCCCEECCCCCCCCCCCEEEEECCCCEECCCCCCCCCCCCCCCCHHHHHHHHHH
AMSITEVTLAEFRQFVEATKARPRATRRGHSVVYDERSGNFIRRSGVDWQSDYNGAQAAP
HHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCEEEECCCCCEEECCCCCCCCCCCCCCCCC
NSPVMHVSIRDAEAYATWLSEQTGRHYHLPSEAEFEYALRAGTTGRYPWGNPGVPPPDAG
CCCEEEEEECCHHHHHHHHHHHCCCEECCCCCCCHHHHEECCCCCCCCCCCCCCCCCCCC
NFTGGNDVSRSGRHWNNGFVGYGDGFWGPAPVGSFRVNAWGLHDMGGNLSEWVADCWHAS
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHH
YRRAPADGAAWFNPGCRQRLVRGGSWANSPLQTRAAWRLSQESDTTSARIGFRLARGI
HCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKEDRLYRSADDAIPLYLAIQQRSEGKDAVSRRGLEQARRRLLERGHALVEQTDRQDNAL
CCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHH
EQARELAIVALALAPEDPKVRALQLEVETAQRVLGFNRAGEDDLRNGRLGEDGNGALVNF
HHHHHHHHEEEEECCCCCCEEEEEEEHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCEEEE
RDAAQLDPDNPRTRQGLAAVESALLRRAEQAAETANFVAARYWLQMAGQVRERAPTIADA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
RARIERMRRAQIAALRDAGLRDLTTPRGLKPAGEKLAEVLRIADPGDPVAGDLRRRLELA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
THYGSFRPGQVFTDGLKVGGRGPQMIVVPHGAFRMGAGDYEPGASDNERPAHYVRFARGF
HHCCCCCCCCEECCCCCCCCCCCEEEEECCCCEECCCCCCCCCCCCCCCCHHHHHHHHHH
AMSITEVTLAEFRQFVEATKARPRATRRGHSVVYDERSGNFIRRSGVDWQSDYNGAQAAP
HHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCEEEECCCCCEEECCCCCCCCCCCCCCCCC
NSPVMHVSIRDAEAYATWLSEQTGRHYHLPSEAEFEYALRAGTTGRYPWGNPGVPPPDAG
CCCEEEEEECCHHHHHHHHHHHCCCEECCCCCCCHHHHEECCCCCCCCCCCCCCCCCCCC
NFTGGNDVSRSGRHWNNGFVGYGDGFWGPAPVGSFRVNAWGLHDMGGNLSEWVADCWHAS
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHH
YRRAPADGAAWFNPGCRQRLVRGGSWANSPLQTRAAWRLSQESDTTSARIGFRLARGI
HCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]