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The map label for this gene is phbC [H]

Identifier: 66768280

GI number: 66768280

Start: 2363065

End: 2364141

Strand: Direct

Name: phbC [H]

Synonym: XC_1959

Alternate gene names: 66768280

Gene position: 2363065-2364141 (Clockwise)

Preceding gene: 66768279

Following gene: 66768281

Centisome position: 45.9

GC content: 63.6

Gene sequence:

>1077_bases
ATGAAGGGCCCGTTGGGATTCAGTGCCGAGGACCTGATGCAGGAGACCTTGTCGATGCAGCGCAAGCTGCGCGAAGGGCT
CAAGCTGCTGCCCGGCGTGGAGGACGTGGATTACGGCGTCACCGAACGGCAGGAAGTCTGGCGCGACGGCAAGGTGGTGC
TGTACCGGTTCGTCGGCGATGCCGCGCCGGTGGCGCGTACGCCGTTGCTGATCGTCTATGCGCTGGTCAACCGGCCGTAC
ATGGTGGACCTGCAGGCCGATCGTTCGCTGGTCAAGGGCCTGCTCGGTCACGGCCAGGACGTCTACGTACTGGATTGGGG
GTATCCGGACCGCTCCGAACGCTATCTCACGCTGGAAGACTATCTACTGCGCTACATCGATGGCGCGGTGGACCATCTGC
GTGCGGCGTCGGGTCTGGAGGCGGTGGACGTGCTCGGCATCTGCCAGGGCGGCACGTTTGCGCTCTGCTATGCCGCGCTG
GAGCGCGCCAAGATCCGCAATCTCATCACCATGGTCACGCCGGTGGATTTCCACACCCCCGACAACATGCTCTCCAACTG
GGCGCGCATGGTCGATGTGGATCTGTTCGTCGACACCATGGGCAATGTGCCTGCGGATCTGATGAATGCCAGTTACCTGA
TGCTCAAGCCGTTCCGGCTCAACCTGCAAAAATACGTGGGGCTGCTCGACATCCTCGATGACAAGCAGGCGCTGGAGGAC
TTCCTGCGCATGGAAAAATGGATCTTCGATTCGCCCGACCTGGCCGGCGAAGCGTTCCGCGAATTCGTCACCCAGTTCTA
CCAGCGCAACGGCCTGGTCACCGGCGATGTGCGTATCGGCGGGCAGGCGGTGGATCTGCACGCTGTCGACATGCCGGTGC
TCAACATCTATGCCGAGCACGATCACCTGGTGCCGCCCGATGCCTCGCGCGCCCTGCGTGGGTTGGTGGGCAGCGAGGAC
TACACCGAGCTGAGCTTTCGCGGTGGGCACATCGGCATCTACGTCTCGGGCCGTGCACAGCGCGAGGTGCCCGTGGCGAT
CCATCGCTGGCTGCAGGCGCGTGGCGGCAACGGTTGA

Upstream 100 bases:

>100_bases
CAGAGACATCCAGACCGAAAGCATCCAACACGCGACCGGCTGCAAAGAAGGCGACCAAGACTTCCAAGTCGCCGGCGCGC
GCACCGAGCGGAGGCAAGCC

Downstream 100 bases:

>100_bases
CGCAGTGATGCAACGGGGTGGGCGTGCGTCACGCACGCGTGCCGTCACGATCCGCTGTAGCTGGCCTGCCTACACTGTGA
GATACATTCCAGGAGGCTGC

Product: poly (3-hydroxybutyric acid) synthase

Products: NA

Alternate protein names: PHA synthase; PHB synthase; Poly(3-hydroxyalkanoate) polymerase; PHA polymerase; Poly(3-hydroxybutyrate) polymerase; PHB polymerase; Polyhydroxyalkanoic acid synthase [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MKGPLGFSAEDLMQETLSMQRKLREGLKLLPGVEDVDYGVTERQEVWRDGKVVLYRFVGDAAPVARTPLLIVYALVNRPY
MVDLQADRSLVKGLLGHGQDVYVLDWGYPDRSERYLTLEDYLLRYIDGAVDHLRAASGLEAVDVLGICQGGTFALCYAAL
ERAKIRNLITMVTPVDFHTPDNMLSNWARMVDVDLFVDTMGNVPADLMNASYLMLKPFRLNLQKYVGLLDILDDKQALED
FLRMEKWIFDSPDLAGEAFREFVTQFYQRNGLVTGDVRIGGQAVDLHAVDMPVLNIYAEHDHLVPPDASRALRGLVGSED
YTELSFRGGHIGIYVSGRAQREVPVAIHRWLQARGGNG

Sequences:

>Translated_358_residues
MKGPLGFSAEDLMQETLSMQRKLREGLKLLPGVEDVDYGVTERQEVWRDGKVVLYRFVGDAAPVARTPLLIVYALVNRPY
MVDLQADRSLVKGLLGHGQDVYVLDWGYPDRSERYLTLEDYLLRYIDGAVDHLRAASGLEAVDVLGICQGGTFALCYAAL
ERAKIRNLITMVTPVDFHTPDNMLSNWARMVDVDLFVDTMGNVPADLMNASYLMLKPFRLNLQKYVGLLDILDDKQALED
FLRMEKWIFDSPDLAGEAFREFVTQFYQRNGLVTGDVRIGGQAVDLHAVDMPVLNIYAEHDHLVPPDASRALRGLVGSED
YTELSFRGGHIGIYVSGRAQREVPVAIHRWLQARGGNG
>Mature_358_residues
MKGPLGFSAEDLMQETLSMQRKLREGLKLLPGVEDVDYGVTERQEVWRDGKVVLYRFVGDAAPVARTPLLIVYALVNRPY
MVDLQADRSLVKGLLGHGQDVYVLDWGYPDRSERYLTLEDYLLRYIDGAVDHLRAASGLEAVDVLGICQGGTFALCYAAL
ERAKIRNLITMVTPVDFHTPDNMLSNWARMVDVDLFVDTMGNVPADLMNASYLMLKPFRLNLQKYVGLLDILDDKQALED
FLRMEKWIFDSPDLAGEAFREFVTQFYQRNGLVTGDVRIGGQAVDLHAVDMPVLNIYAEHDHLVPPDASRALRGLVGSED
YTELSFRGGHIGIYVSGRAQREVPVAIHRWLQARGGNG

Specific function: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation [H]

COG id: COG3243

COG function: function code I; Poly(3-hydroxyalkanoate) synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHA/PHB synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010125 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 40194; Mature: 40194

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGPLGFSAEDLMQETLSMQRKLREGLKLLPGVEDVDYGVTERQEVWRDGKVVLYRFVGD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEEEEECCC
AAPVARTPLLIVYALVNRPYMVDLQADRSLVKGLLGHGQDVYVLDWGYPDRSERYLTLED
CCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEHHH
YLLRYIDGAVDHLRAASGLEAVDVLGICQGGTFALCYAALERAKIRNLITMVTPVDFHTP
HHHHHHHHHHHHHHHHCCCCHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DNMLSNWARMVDVDLFVDTMGNVPADLMNASYLMLKPFRLNLQKYVGLLDILDDKQALED
HHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEHHHHCHHHHHHHHHHHCCHHHHHH
FLRMEKWIFDSPDLAGEAFREFVTQFYQRNGLVTGDVRIGGQAVDLHAVDMPVLNIYAEH
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCEEEEEEEECCCCEEEEECC
DHLVPPDASRALRGLVGSEDYTELSFRGGHIGIYVSGRAQREVPVAIHRWLQARGGNG
CCCCCCCHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKGPLGFSAEDLMQETLSMQRKLREGLKLLPGVEDVDYGVTERQEVWRDGKVVLYRFVGD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEEEEECCC
AAPVARTPLLIVYALVNRPYMVDLQADRSLVKGLLGHGQDVYVLDWGYPDRSERYLTLED
CCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEHHH
YLLRYIDGAVDHLRAASGLEAVDVLGICQGGTFALCYAALERAKIRNLITMVTPVDFHTP
HHHHHHHHHHHHHHHHCCCCHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DNMLSNWARMVDVDLFVDTMGNVPADLMNASYLMLKPFRLNLQKYVGLLDILDDKQALED
HHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEHHHHCHHHHHHHHHHHCCHHHHHH
FLRMEKWIFDSPDLAGEAFREFVTQFYQRNGLVTGDVRIGGQAVDLHAVDMPVLNIYAEH
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCEEEEEEEECCCCEEEEECC
DHLVPPDASRALRGLVGSEDYTELSFRGGHIGIYVSGRAQREVPVAIHRWLQARGGNG
CCCCCCCHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1396692 [H]