Click here to switch to the map view.

The map label for this gene is 66768240

Identifier: 66768240

GI number: 66768240

Start: 2319198

End: 2320082

Strand: Reverse

Name: 66768240

Synonym: XC_1919

Alternate gene names: NA

Gene position: 2320082-2319198 (Counterclockwise)

Preceding gene: 66768241

Following gene: 66768239

Centisome position: 45.06

GC content: 66.78

Gene sequence:

>885_bases
ATGACCCGACATCTCCTTCCCGTCGCGCTGATCCAGGAGCGCAACCACGGCGACGCCGAGGCCAATCTGGCCGTCATCGA
GTCGCGCGTGGCCGAAGCCGCCGCGCAGGGCGCCAAACTGGTGCTGCTGCAGGAACTGCACAACGGCGCGTATTTCTGCC
AGCACGAATCGGTAGACGTGTTCGATCTGGCCGAGCCGATTCCCGGCCCCAGCACCGAGCGCCTGGGCGCGCTGGCCAAG
CAGCATGGCGTGGTGATCGTGGCCTCGTTGTTCGAGCGCCGCGCCGCCGGCCTGTACCACAACACTGCCGTGGTGCTGGA
GGCGGACGGCCGTTTGCTTGGCAAGTACCGCAAGATGCACATCCCCGACGACCCGGGCTTCTACGAGAAGTTCTACTTCA
CCCCGGGCGATCTGGGCTTTACGCCGGTGGATACCTCGGTCGGCCGGCTCGGCGTGTTGGTGTGCTGGGACCAGTGGTAC
CCGGAAGCGGCGCGCCTGATGGCGCTGGCTGGTGCCGAATTGCTGCTCTACCCCACCGCGATCGGTTGGGATCCGGACGA
TGCGCAGGCCGAGCAGGAACGCCAGCGCGATGCGTGGGTGCTGAGCCATCGCGGCCATGCGGTGGCCAACGGCGTGCCGG
TGCTGTCGTGCAACCGTGTCGGTCACGAGCCGTCGCCGATCGGTGCTTCGGGCATCCAGTTCTGGGGCAATAGCCACGTG
CTGGGGCCGCAGGGCGAGTTCATTGCCGAAGCCGGGCAGGATCCGACCATCCTGGTGTGCGATGTGGACCTGCAGCGCAG
CGAGCATGTGCGGCGCATCTGGCCGTTCCTGCGCGACCGCCGCATCGACGCGTATGGCGATCTGCTCAAGCGTTACATCG
ACTGA

Upstream 100 bases:

>100_bases
TGCCGGCCTGCTGGCCGCCTGACCCGTATTGTTCCGGCCGGCAGGCCGGCGTTCCACCATGGCGCGCTACCCTGTGCGCC
ACCTAGCAGGACGAGTAGCC

Downstream 100 bases:

>100_bases
CCGCGCATGCCCGTCGAGCTGCGTGAGGTCCGCGACGCGGACATCCCGGCGATCACCGCGATCTACGCGGAGCAGATCGC
CGGGTGCAACACCTACGAAT

Product: beta-alanine synthetase

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MTRHLLPVALIQERNHGDAEANLAVIESRVAEAAAQGAKLVLLQELHNGAYFCQHESVDVFDLAEPIPGPSTERLGALAK
QHGVVIVASLFERRAAGLYHNTAVVLEADGRLLGKYRKMHIPDDPGFYEKFYFTPGDLGFTPVDTSVGRLGVLVCWDQWY
PEAARLMALAGAELLLYPTAIGWDPDDAQAEQERQRDAWVLSHRGHAVANGVPVLSCNRVGHEPSPIGASGIQFWGNSHV
LGPQGEFIAEAGQDPTILVCDVDLQRSEHVRRIWPFLRDRRIDAYGDLLKRYID

Sequences:

>Translated_294_residues
MTRHLLPVALIQERNHGDAEANLAVIESRVAEAAAQGAKLVLLQELHNGAYFCQHESVDVFDLAEPIPGPSTERLGALAK
QHGVVIVASLFERRAAGLYHNTAVVLEADGRLLGKYRKMHIPDDPGFYEKFYFTPGDLGFTPVDTSVGRLGVLVCWDQWY
PEAARLMALAGAELLLYPTAIGWDPDDAQAEQERQRDAWVLSHRGHAVANGVPVLSCNRVGHEPSPIGASGIQFWGNSHV
LGPQGEFIAEAGQDPTILVCDVDLQRSEHVRRIWPFLRDRRIDAYGDLLKRYID
>Mature_293_residues
TRHLLPVALIQERNHGDAEANLAVIESRVAEAAAQGAKLVLLQELHNGAYFCQHESVDVFDLAEPIPGPSTERLGALAKQ
HGVVIVASLFERRAAGLYHNTAVVLEADGRLLGKYRKMHIPDDPGFYEKFYFTPGDLGFTPVDTSVGRLGVLVCWDQWYP
EAARLMALAGAELLLYPTAIGWDPDDAQAEQERQRDAWVLSHRGHAVANGVPVLSCNRVGHEPSPIGASGIQFWGNSHVL
GPQGEFIAEAGQDPTILVCDVDLQRSEHVRRIWPFLRDRRIDAYGDLLKRYID

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=289, Percent_Identity=32.8719723183391, Blast_Score=144, Evalue=8e-35,
Organism=Homo sapiens, GI297632348, Length=291, Percent_Identity=28.1786941580756, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI297632350, Length=291, Percent_Identity=28.1786941580756, Blast_Score=107, Evalue=9e-24,
Organism=Homo sapiens, GI5031947, Length=291, Percent_Identity=28.1786941580756, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI7706509, Length=280, Percent_Identity=30.7142857142857, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI297632346, Length=195, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17533173, Length=311, Percent_Identity=29.903536977492, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17556280, Length=292, Percent_Identity=25.3424657534247, Blast_Score=95, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6323383, Length=299, Percent_Identity=30.4347826086957, Blast_Score=117, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6322335, Length=318, Percent_Identity=25.1572327044025, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21358471, Length=288, Percent_Identity=30.5555555555556, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21355835, Length=293, Percent_Identity=26.6211604095563, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17933642, Length=286, Percent_Identity=27.2727272727273, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: NA

Molecular weight: Translated: 32514; Mature: 32383

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRHLLPVALIQERNHGDAEANLAVIESRVAEAAAQGAKLVLLQELHNGAYFCQHESVDV
CCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEHHCCCEEEEECCCCCH
FDLAEPIPGPSTERLGALAKQHGVVIVASLFERRAAGLYHNTAVVLEADGRLLGKYRKMH
HHHCCCCCCCCHHHHHHHHHHCCEEEEHHHHHHHHCCCEECEEEEEECCCCEEHHHHCCC
IPDDPGFYEKFYFTPGDLGFTPVDTSVGRLGVLVCWDQWYPEAARLMALAGAELLLYPTA
CCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCEEEEEEEE
IGWDPDDAQAEQERQRDAWVLSHRGHAVANGVPVLSCNRVGHEPSPIGASGIQFWGNSHV
CCCCCCHHHHHHHHHHCCEEEECCCCCHHCCCCEEEECCCCCCCCCCCCCCCEECCCCEE
LGPQGEFIAEAGQDPTILVCDVDLQRSEHVRRIWPFLRDRRIDAYGDLLKRYID
ECCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TRHLLPVALIQERNHGDAEANLAVIESRVAEAAAQGAKLVLLQELHNGAYFCQHESVDV
CCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEHHCCCEEEEECCCCCH
FDLAEPIPGPSTERLGALAKQHGVVIVASLFERRAAGLYHNTAVVLEADGRLLGKYRKMH
HHHCCCCCCCCHHHHHHHHHHCCEEEEHHHHHHHHCCCEECEEEEEECCCCEEHHHHCCC
IPDDPGFYEKFYFTPGDLGFTPVDTSVGRLGVLVCWDQWYPEAARLMALAGAELLLYPTA
CCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCEEEEEEEE
IGWDPDDAQAEQERQRDAWVLSHRGHAVANGVPVLSCNRVGHEPSPIGASGIQFWGNSHV
CCCCCCHHHHHHHHHHCCEEEECCCCCHHCCCCEEEECCCCCCCCCCCCCCCEECCCCEE
LGPQGEFIAEAGQDPTILVCDVDLQRSEHVRRIWPFLRDRRIDAYGDLLKRYID
ECCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8526497 [H]