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The map label for this gene is 66768238

Identifier: 66768238

GI number: 66768238

Start: 2317439

End: 2318671

Strand: Reverse

Name: 66768238

Synonym: XC_1917

Alternate gene names: NA

Gene position: 2318671-2317439 (Counterclockwise)

Preceding gene: 66768239

Following gene: 77761175

Centisome position: 45.03

GC content: 67.07

Gene sequence:

>1233_bases
ATGAATGACCCCATGACCGAAATCACCCCCGTGTTGCAGGACGATGCGCTGTCCGGCCAGCCGCACCGCATCGTCGAACG
CGACGGTGTGCGCTACACCCTGCTCGGCACCGCGCATGTCTCGCTGGCAAGCGTGGCCGCGGTGCAGCGGGCGATCGGCA
GCGGCCGGTACGACGCGGTGGCCGTGGAGCTGGACGCGCAGCGCCTGCAGGCGCTCAGCGACCCCGATGCCCTCGCCCGC
CTGGATCTGGTGCAGGTAATCCGGAAGGGTCGCGTGGCGCTGTTCGCCGCCAACCTGGCATTGGCCGCCTACCAACGTCG
CCTGGCCAAGCAGTTGGGCATCGAGCCGGGTGCGGAGCTGAAGGAAGCGGTGAACCTGGCACGTGCGCAGGGCCTGCCGG
TGCATTTGATCGACCGCGAAGTGGGGCTGACCTTCAAACGTGCTTCCGGGCGGCTGGGCTTCTTCGGCAAGATGAAGCTG
GCCGGTGGCCTGCTGGCGGGGCTGTTCGCCGCTGACGAAGTGGGCGAAGAAGAGATCGAAAAGCTCAAGCAAGGCGACAT
GCTGGAGGCCAGTTTCGGCGATTTCGCCAGCGAAAGCCCGGAGCTGTACGAGACGGTGATTGCCGAGCGCGATCGCTACA
TGGCCACGCGGCTGCGCGAAGAAGCTAGCCCCACCCAGCGCGAGGTACTGGCCGTGGTCGGCGCTGGCCATCTTGCCGGG
CTCGCCCGCCACCTTGCGCAGGACACCGATGCGCCCGGCCCGCTGCGCGAGTCGCTGGAATACGTGCAGCAGCGCAAGCG
TATTCCCTGGATCACGCTGGGCATGCTGACGGTGATCGTTGCCGGGATCGGGATCGGGTTCTGGCGCGGCGGCATGTCGA
TGGGTGCGGACCTGCTGCTGCAATGGGCGATGTACACCGGCGGCCTGGCAGCGCTGGGCTGCCTATTGGCCGGTAGTCAT
CCGCTGAGCATTCTCACCGCCGCGGTGGTGGCACCGTTCAAGCCGTTCCGGCTGAGCGTGCCGACCGGCGCGTTCGCCGC
CTTGGTCGAAGTGCATATGCGCAAGCCGGCCTATGGCGACTTCCTCACCCTGCGCGACGATGCACAGACCTTGCGTGGCT
GGTACCGCAATCGTGTGTCGCGGGTGGTGCTGACGTTCCTGCTGACCAACCTGGGCAGCGGCGCGGGCGTGTGGCTGGCC
GGTGTGCAGATTTTTCAGCGCCTGCATGGGTGA

Upstream 100 bases:

>100_bases
GTCGGAGTCTTCACCGGACTGGGCCGCAAGCATGGCCGCTGGTTGGACGCGGTGCAGATGCAGCGCCCGCTCGGCTCCGG
TCACACCGCCCCTCCTTCCG

Downstream 100 bases:

>100_bases
GTTGGGGGAGCGCGGCCGCCGCATCAGCAGTTGATGCGGTCCTACCGTTGTAGGAGCGCACCTGGACGCAATGGTGACTT
GCGCGACTGACAGCTGGAAT

Product: pheromone shutdown protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MNDPMTEITPVLQDDALSGQPHRIVERDGVRYTLLGTAHVSLASVAAVQRAIGSGRYDAVAVELDAQRLQALSDPDALAR
LDLVQVIRKGRVALFAANLALAAYQRRLAKQLGIEPGAELKEAVNLARAQGLPVHLIDREVGLTFKRASGRLGFFGKMKL
AGGLLAGLFAADEVGEEEIEKLKQGDMLEASFGDFASESPELYETVIAERDRYMATRLREEASPTQREVLAVVGAGHLAG
LARHLAQDTDAPGPLRESLEYVQQRKRIPWITLGMLTVIVAGIGIGFWRGGMSMGADLLLQWAMYTGGLAALGCLLAGSH
PLSILTAAVVAPFKPFRLSVPTGAFAALVEVHMRKPAYGDFLTLRDDAQTLRGWYRNRVSRVVLTFLLTNLGSGAGVWLA
GVQIFQRLHG

Sequences:

>Translated_410_residues
MNDPMTEITPVLQDDALSGQPHRIVERDGVRYTLLGTAHVSLASVAAVQRAIGSGRYDAVAVELDAQRLQALSDPDALAR
LDLVQVIRKGRVALFAANLALAAYQRRLAKQLGIEPGAELKEAVNLARAQGLPVHLIDREVGLTFKRASGRLGFFGKMKL
AGGLLAGLFAADEVGEEEIEKLKQGDMLEASFGDFASESPELYETVIAERDRYMATRLREEASPTQREVLAVVGAGHLAG
LARHLAQDTDAPGPLRESLEYVQQRKRIPWITLGMLTVIVAGIGIGFWRGGMSMGADLLLQWAMYTGGLAALGCLLAGSH
PLSILTAAVVAPFKPFRLSVPTGAFAALVEVHMRKPAYGDFLTLRDDAQTLRGWYRNRVSRVVLTFLLTNLGSGAGVWLA
GVQIFQRLHG
>Mature_410_residues
MNDPMTEITPVLQDDALSGQPHRIVERDGVRYTLLGTAHVSLASVAAVQRAIGSGRYDAVAVELDAQRLQALSDPDALAR
LDLVQVIRKGRVALFAANLALAAYQRRLAKQLGIEPGAELKEAVNLARAQGLPVHLIDREVGLTFKRASGRLGFFGKMKL
AGGLLAGLFAADEVGEEEIEKLKQGDMLEASFGDFASESPELYETVIAERDRYMATRLREEASPTQREVLAVVGAGHLAG
LARHLAQDTDAPGPLRESLEYVQQRKRIPWITLGMLTVIVAGIGIGFWRGGMSMGADLLLQWAMYTGGLAALGCLLAGSH
PLSILTAAVVAPFKPFRLSVPTGAFAALVEVHMRKPAYGDFLTLRDDAQTLRGWYRNRVSRVVLTFLLTNLGSGAGVWLA
GVQIFQRLHG

Specific function: Unknown

COG id: COG1916

COG function: function code S; Uncharacterized homolog of PrgY (pheromone shutdown protein)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI33342278, Length=209, Percent_Identity=33.4928229665072, Blast_Score=103, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71988206, Length=307, Percent_Identity=26.0586319218241, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71988217, Length=307, Percent_Identity=26.0586319218241, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24646455, Length=209, Percent_Identity=30.1435406698565, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357445, Length=209, Percent_Identity=30.1435406698565, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002816
- InterPro:   IPR005230 [H]

Pfam domain/function: PF01963 TraB [H]

EC number: NA

Molecular weight: Translated: 44296; Mature: 44296

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDPMTEITPVLQDDALSGQPHRIVERDGVRYTLLGTAHVSLASVAAVQRAIGSGRYDAV
CCCCHHHHHHHHHCCCCCCCCCHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCEE
AVELDAQRLQALSDPDALARLDLVQVIRKGRVALFAANLALAAYQRRLAKQLGIEPGAEL
EEEECHHHHHHCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCCCCHHH
KEAVNLARAQGLPVHLIDREVGLTFKRASGRLGFFGKMKLAGGLLAGLFAADEVGEEEIE
HHHHHHHHHCCCCEEEECHHHCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHCCHHHHH
KLKQGDMLEASFGDFASESPELYETVIAERDRYMATRLREEASPTQREVLAVVGAGHLAG
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHH
LARHLAQDTDAPGPLRESLEYVQQRKRIPWITLGMLTVIVAGIGIGFWRGGMSMGADLLL
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
QWAMYTGGLAALGCLLAGSHPLSILTAAVVAPFKPFRLSVPTGAFAALVEVHMRKPAYGD
HHHHHHCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHCCCCCCC
FLTLRDDAQTLRGWYRNRVSRVVLTFLLTNLGSGAGVWLAGVQIFQRLHG
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNDPMTEITPVLQDDALSGQPHRIVERDGVRYTLLGTAHVSLASVAAVQRAIGSGRYDAV
CCCCHHHHHHHHHCCCCCCCCCHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCEE
AVELDAQRLQALSDPDALARLDLVQVIRKGRVALFAANLALAAYQRRLAKQLGIEPGAEL
EEEECHHHHHHCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCCCCHHH
KEAVNLARAQGLPVHLIDREVGLTFKRASGRLGFFGKMKLAGGLLAGLFAADEVGEEEIE
HHHHHHHHHCCCCEEEECHHHCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHCCHHHHH
KLKQGDMLEASFGDFASESPELYETVIAERDRYMATRLREEASPTQREVLAVVGAGHLAG
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHH
LARHLAQDTDAPGPLRESLEYVQQRKRIPWITLGMLTVIVAGIGIGFWRGGMSMGADLLL
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
QWAMYTGGLAALGCLLAGSHPLSILTAAVVAPFKPFRLSVPTGAFAALVEVHMRKPAYGD
HHHHHHCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHCCCCCCC
FLTLRDDAQTLRGWYRNRVSRVVLTFLLTNLGSGAGVWLAGVQIFQRLHG
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]