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The map label for this gene is metX

Identifier: 66768210

GI number: 66768210

Start: 2285745

End: 2286887

Strand: Reverse

Name: metX

Synonym: XC_1889

Alternate gene names: 66768210

Gene position: 2286887-2285745 (Counterclockwise)

Preceding gene: 66768211

Following gene: 66768209

Centisome position: 44.42

GC content: 65.97

Gene sequence:

>1143_bases
ATGACCGAATTCATTCCCACCGGTACCCGCTTCCACGCCCTGCCCTCGCCGTTGCCGATGAAACGCGGCGGTGTACTGCA
TCAGGCCAGGGTGGCCTATGAAACCTGGGGCACGCTGGATGCGGACCACGGCAATGCCGTGTTGATCGTCACCGGCCTGT
CGCCCAATGCCCACGCCGCGGCCAATGCCGACAACCCCGAGCCCGGTTGGTGGGAAGCGATGGTGGGCCCGGGCAAGCCG
ATCGACACCGATCGCTGGTTCGTGGTGTGCGTCAACTCGTTGGGCAGTTGCAAAGGCTCCACCGGCCCGGCTTCGATCGA
CCCGGCCACCGGCGCGCCCTACCGGCTGTCGTTCCCCGAATTGTCCATCGAAGATGTCGCCGATGCCGCGGCCGATGTGG
TGCGCGCACTGGGCATCGCGCAGCTGGCCTGCCTGATCGGCAACTCGATGGGGGGCATGACCGCGTTGGCGTTGCTGCTG
CGCCACCCGGGCATCGCGCGCAGCCACATCAACATCTCCGGCAGCGCGCAGGCGTTGCCGTTTTCGATCGCCATCCGCTC
GCTGCAGCGCGAAGCCATTCGCCTGGATCCGCACTGGAACGGCGGCCACTACGACGATGTGCAGTACCCGGAATCGGGCA
TGCGCATGGCGCGCAAGCTGGGCGTGATCACTTACCGCTCGGCGCTGGAATGGGATGGCCGTTTCGGCCGCGTGCGGCTG
GATTCCGAACTGACCGCCGAGGATCCATTCGGGCTCGAATTCCAGGTCGAAAGCTATCTCGAAGGCCATGCACGCCGCTT
CGTGCGCTTCTTCGACCCCAACTGCTATCTCTATCTAAGCCGCTCGATGGATTGGTTCGATCTGGCCGAATACGCACCGG
ACACACGCGCCGACGCCGCAGCGCCAGAATCCGGCGTGCTGGCAGGGCTGGCGCAGATCCGCATCGCGCGCGCACTGGCG
ATCGGCGCCAACACCGACATCTTGTTCCCGGTGCAGCAGCAGGAACAGATTGCCGAAGGCCTGCGTGCCGGGGGCGCCGA
TGCACAGTTCCTGGGCCTGGATTCCCCGCAGGGCCACGACGCCTTCCTGGTGGATTTCGCCCGCTTCGGCCCGGCAGTGC
GGGCCTTTCTTGCAGACTGCTGA

Upstream 100 bases:

>100_bases
GCGCACTGCCCACGCCCTCACAGCGCGACAGCGCGACAGCGCGACAGCGCGTGCCAAGCGTACGCATGCCGGCTCCCGCC
ATGCCGGATAGAATCACGCG

Downstream 100 bases:

>100_bases
GCCGCTCATGGTGGGGGATCGATGCGTTATCAGGGGCGTCTGAGCGATTGGGATGACCACAAGGGCTTCGGGTTCGTCGT
GCCGCATGGCGGTGGCGAGC

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MTEFIPTGTRFHALPSPLPMKRGGVLHQARVAYETWGTLDADHGNAVLIVTGLSPNAHAAANADNPEPGWWEAMVGPGKP
IDTDRWFVVCVNSLGSCKGSTGPASIDPATGAPYRLSFPELSIEDVADAAADVVRALGIAQLACLIGNSMGGMTALALLL
RHPGIARSHINISGSAQALPFSIAIRSLQREAIRLDPHWNGGHYDDVQYPESGMRMARKLGVITYRSALEWDGRFGRVRL
DSELTAEDPFGLEFQVESYLEGHARRFVRFFDPNCYLYLSRSMDWFDLAEYAPDTRADAAAPESGVLAGLAQIRIARALA
IGANTDILFPVQQQEQIAEGLRAGGADAQFLGLDSPQGHDAFLVDFARFGPAVRAFLADC

Sequences:

>Translated_380_residues
MTEFIPTGTRFHALPSPLPMKRGGVLHQARVAYETWGTLDADHGNAVLIVTGLSPNAHAAANADNPEPGWWEAMVGPGKP
IDTDRWFVVCVNSLGSCKGSTGPASIDPATGAPYRLSFPELSIEDVADAAADVVRALGIAQLACLIGNSMGGMTALALLL
RHPGIARSHINISGSAQALPFSIAIRSLQREAIRLDPHWNGGHYDDVQYPESGMRMARKLGVITYRSALEWDGRFGRVRL
DSELTAEDPFGLEFQVESYLEGHARRFVRFFDPNCYLYLSRSMDWFDLAEYAPDTRADAAAPESGVLAGLAQIRIARALA
IGANTDILFPVQQQEQIAEGLRAGGADAQFLGLDSPQGHDAFLVDFARFGPAVRAFLADC
>Mature_379_residues
TEFIPTGTRFHALPSPLPMKRGGVLHQARVAYETWGTLDADHGNAVLIVTGLSPNAHAAANADNPEPGWWEAMVGPGKPI
DTDRWFVVCVNSLGSCKGSTGPASIDPATGAPYRLSFPELSIEDVADAAADVVRALGIAQLACLIGNSMGGMTALALLLR
HPGIARSHINISGSAQALPFSIAIRSLQREAIRLDPHWNGGHYDDVQYPESGMRMARKLGVITYRSALEWDGRFGRVRLD
SELTAEDPFGLEFQVESYLEGHARRFVRFFDPNCYLYLSRSMDWFDLAEYAPDTRADAAAPESGVLAGLAQIRIARALAI
GANTDILFPVQQQEQIAEGLRAGGADAQFLGLDSPQGHDAFLVDFARFGPAVRAFLADC

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=231, Percent_Identity=31.1688311688312, Blast_Score=124, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_XANC8 (Q4UVH1)

Other databases:

- EMBL:   CP000050
- RefSeq:   YP_242972.1
- ProteinModelPortal:   Q4UVH1
- SMR:   Q4UVH1
- STRING:   Q4UVH1
- GeneID:   3380436
- GenomeReviews:   CP000050_GR
- KEGG:   xcb:XC_1889
- eggNOG:   COG2021
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- PhylomeDB:   Q4UVH1
- ProtClustDB:   PRK00175
- BioCyc:   XCAM314565:XC_1889-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 41032; Mature: 40901

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: ACT_SITE 149-149 ACT_SITE 359-359

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFIPTGTRFHALPSPLPMKRGGVLHQARVAYETWGTLDADHGNAVLIVTGLSPNAHAA
CCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHCCCEECCCCCEEEEEECCCCCCCCC
ANADNPEPGWWEAMVGPGKPIDTDRWFVVCVNSLGSCKGSTGPASIDPATGAPYRLSFPE
CCCCCCCCCCEEEECCCCCCCCCCCEEEEEECHHCCCCCCCCCCCCCCCCCCCEEECCCC
LSIEDVADAAADVVRALGIAQLACLIGNSMGGMTALALLLRHPGIARSHINISGSAQALP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCH
FSIAIRSLQREAIRLDPHWNGGHYDDVQYPESGMRMARKLGVITYRSALEWDGRFGRVRL
HHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHCHHEEHHHHCCCCCCCEEEE
DSELTAEDPFGLEFQVESYLEGHARRFVRFFDPNCYLYLSRSMDWFDLAEYAPDTRADAA
CCCCCCCCCCCCEEEHHHHHHHHHHHHHEEECCCEEEEEECCCCHHHHHHHCCCCCCCCC
APESGVLAGLAQIRIARALAIGANTDILFPVQQQEQIAEGLRAGGADAQFLGLDSPQGHD
CCCCHHHHHHHHHHHHHHHEECCCCCEEEECHHHHHHHHHHHCCCCCCEEEECCCCCCCC
AFLVDFARFGPAVRAFLADC
CEEEEHHHHCHHHHHHHHCC
>Mature Secondary Structure 
TEFIPTGTRFHALPSPLPMKRGGVLHQARVAYETWGTLDADHGNAVLIVTGLSPNAHAA
CCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHCCCEECCCCCEEEEEECCCCCCCCC
ANADNPEPGWWEAMVGPGKPIDTDRWFVVCVNSLGSCKGSTGPASIDPATGAPYRLSFPE
CCCCCCCCCCEEEECCCCCCCCCCCEEEEEECHHCCCCCCCCCCCCCCCCCCCEEECCCC
LSIEDVADAAADVVRALGIAQLACLIGNSMGGMTALALLLRHPGIARSHINISGSAQALP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCH
FSIAIRSLQREAIRLDPHWNGGHYDDVQYPESGMRMARKLGVITYRSALEWDGRFGRVRL
HHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHCHHEEHHHHCCCCCCCEEEE
DSELTAEDPFGLEFQVESYLEGHARRFVRFFDPNCYLYLSRSMDWFDLAEYAPDTRADAA
CCCCCCCCCCCCEEEHHHHHHHHHHHHHEEECCCEEEEEECCCCHHHHHHHCCCCCCCCC
APESGVLAGLAQIRIARALAIGANTDILFPVQQQEQIAEGLRAGGADAQFLGLDSPQGHD
CCCCHHHHHHHHHHHHHHHEECCCCCEEEECHHHHHHHHHHHCCCCCCEEEECCCCCCCC
AFLVDFARFGPAVRAFLADC
CEEEEHHHHCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA