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The map label for this gene is ubiG [H]

Identifier: 66768167

GI number: 66768167

Start: 2240829

End: 2241548

Strand: Direct

Name: ubiG [H]

Synonym: XC_1846

Alternate gene names: 66768167

Gene position: 2240829-2241548 (Clockwise)

Preceding gene: 66768166

Following gene: 66768168

Centisome position: 43.52

GC content: 65.83

Gene sequence:

>720_bases
ATGAATCCGAATCCACAATCCACATCGTCCAATTTCCACCAGACCGAGCTGGACAAGTTCGCTGCGCTGGCCAACCGCTG
GTGGGATGCCGACGGCCCGCAGAAGCCGCTGCATGCGCTCAATCCGGTGCGGCTGGACTACGTGGCCGCACGGGTTGCGC
TGCCGGGCGCACGCGTGCTCGACGTCGGCTGCGGTGGTGGCCTGCTCAGTGAAGCGATGGCGCGCCTGGGCGCGCAAGTC
ACCGCGATCGACCTGGCGCCGGAGCTGGTGAAAGTGGCGCGCCTGCACAGCCTGGAATCGAGCGTGCAGGTGGACTACCG
CGTGCAGTCGGTGGAAGACCTGGCTGCCGAGCAGCCGGGCAGCTTCGATGCGGTGACCTGCATGGAAATGCTGGAGCACG
TGCCAGACCCGCTGGCGATCATCCGCGCCTGCGCAAGCCTGCTCAAGCCGGGCGGCACGCTGTTCCTGTCTACACTCAAT
CGCACGCCGGCAGCGTTTGCGCTGGCGGTAGTAGGCGCCGAATACATCGCGCGGTTGCTGCCCAAGGGCACGCATCACTA
CAAGGATTTCATCAAGCCGTCCGAACTGGCCGCCTGGCTGCGCACTGCCGAGCTGCAGCTGCAAGACGTCAGCGGCATGC
TGTACGAGCCGTGGCGCAACCGCGCGCGCTTGTCCTCGCGCACCGAAGTGAACTATCTGGCGTGTGCGGTGAAGCCGTGA

Upstream 100 bases:

>100_bases
GACATGGATACCGCTGCCCTGGTCGCCAACGCGCGCCAGTGGCGCGACCGTATCCGCACCGTCCGCGCCTGAGCGCGGCC
ATCGCATCACGGAGAGCCAC

Downstream 100 bases:

>100_bases
CGAGCGGGGAATGGGGAATCGGGATTCGGGAATCGCAACGGCGGTTGGTTGCGGTCTTGATGTCGACCGGTTCCTGTCTG
ATGGCCGATCGCGCTGGGAT

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MNPNPQSTSSNFHQTELDKFAALANRWWDADGPQKPLHALNPVRLDYVAARVALPGARVLDVGCGGGLLSEAMARLGAQV
TAIDLAPELVKVARLHSLESSVQVDYRVQSVEDLAAEQPGSFDAVTCMEMLEHVPDPLAIIRACASLLKPGGTLFLSTLN
RTPAAFALAVVGAEYIARLLPKGTHHYKDFIKPSELAAWLRTAELQLQDVSGMLYEPWRNRARLSSRTEVNYLACAVKP

Sequences:

>Translated_239_residues
MNPNPQSTSSNFHQTELDKFAALANRWWDADGPQKPLHALNPVRLDYVAARVALPGARVLDVGCGGGLLSEAMARLGAQV
TAIDLAPELVKVARLHSLESSVQVDYRVQSVEDLAAEQPGSFDAVTCMEMLEHVPDPLAIIRACASLLKPGGTLFLSTLN
RTPAAFALAVVGAEYIARLLPKGTHHYKDFIKPSELAAWLRTAELQLQDVSGMLYEPWRNRARLSSRTEVNYLACAVKP
>Mature_239_residues
MNPNPQSTSSNFHQTELDKFAALANRWWDADGPQKPLHALNPVRLDYVAARVALPGARVLDVGCGGGLLSEAMARLGAQV
TAIDLAPELVKVARLHSLESSVQVDYRVQSVEDLAAEQPGSFDAVTCMEMLEHVPDPLAIIRACASLLKPGGTLFLSTLN
RTPAAFALAVVGAEYIARLLPKGTHHYKDFIKPSELAAWLRTAELQLQDVSGMLYEPWRNRARLSSRTEVNYLACAVKP

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=237, Percent_Identity=40.5063291139241, Blast_Score=191, Evalue=6e-49,
Organism=Escherichia coli, GI1788564, Length=234, Percent_Identity=52.1367521367521, Blast_Score=265, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI115533050, Length=236, Percent_Identity=34.3220338983051, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6324476, Length=263, Percent_Identity=33.4600760456274, Blast_Score=152, Evalue=3e-38,
Organism=Drosophila melanogaster, GI281365311, Length=244, Percent_Identity=36.8852459016393, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24585589, Length=265, Percent_Identity=33.9622641509434, Blast_Score=152, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 26039; Mature: 26039

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPNPQSTSSNFHQTELDKFAALANRWWDADGPQKPLHALNPVRLDYVAARVALPGARVL
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCEEE
DVGCGGGLLSEAMARLGAQVTAIDLAPELVKVARLHSLESSVQVDYRVQSVEDLAAEQPG
EECCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SFDAVTCMEMLEHVPDPLAIIRACASLLKPGGTLFLSTLNRTPAAFALAVVGAEYIARLL
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEHHCCCHHHHHHHHHHHHHHHHHC
PKGTHHYKDFIKPSELAAWLRTAELQLQDVSGMLYEPWRNRARLSSRTEVNYLACAVKP
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEEECC
>Mature Secondary Structure
MNPNPQSTSSNFHQTELDKFAALANRWWDADGPQKPLHALNPVRLDYVAARVALPGARVL
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCEEE
DVGCGGGLLSEAMARLGAQVTAIDLAPELVKVARLHSLESSVQVDYRVQSVEDLAAEQPG
EECCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SFDAVTCMEMLEHVPDPLAIIRACASLLKPGGTLFLSTLNRTPAAFALAVVGAEYIARLL
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEHHCCCHHHHHHHHHHHHHHHHHC
PKGTHHYKDFIKPSELAAWLRTAELQLQDVSGMLYEPWRNRARLSSRTEVNYLACAVKP
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]