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The map label for this gene is yciR [C]

Identifier: 66768162

GI number: 66768162

Start: 2234514

End: 2236631

Strand: Direct

Name: yciR [C]

Synonym: XC_1841

Alternate gene names: 66768162

Gene position: 2234514-2236631 (Clockwise)

Preceding gene: 66768161

Following gene: 66768164

Centisome position: 43.4

GC content: 66.95

Gene sequence:

>2118_bases
ATGACGCAGGTGCGCTTTGGATTGCAGGCCCGGTTCCTGCTGGTGATGGCGCTGACGCTGTTGCTGGTCGGCGCCATCCT
GGCCTCGCTGTTGCAGCGGCAAAGTTCGATGCAGCGCGAGGTGCGCAGCCTGAGCGCGCAGATCCTGCATGAGTTGTTCG
ACCGCAGCCTGCGCACGCGTGGCGAGACCCTGGCCACCGAGCTGGCCTCGGGCCTGGCCAACCCGCTGTACTACTCGGAT
CTGGCGGCGGTGGGCGCGCTGGTGCGCAACGCCTCGCGCCAGCAGGTGGTGAGCTACGTGCGGGTGTTCGACCGCCGCGG
CCGGCTGGTGCACGACGGCAGCGCCACGCTGCAGGGCTATGGCCAGCCCATGCAGGACCCGCTCGCTGCCAAGGCGATCG
CCGCGCCGGCCCTGCTGTTGCAGTCTTCGCCGGAAGTGCTGGATGTGACGGTGCCGATCAAGGTCGGCGACCAGCGCATC
GGCGGCGTGCGGGTGGGCATGTCGCGCGAGCGCGTGCGCAAGATCGAATCCAGCGCCAACCTCACCCTGGTGCAGAATCT
CAATGCGATCGGCAAGCGCGATCTGGGCTGGCTGCTGGTACTGCTGGCAGCGCTGGTGGCGCTAGGAATCCTGCTGGCCA
TCTATGTGCAACGCACGCTGGTCGCGCCGGTGCGCCTGCTGGCGGCGGCGGCGCGGCAGATCGAACGTGGCGACTATCTG
GTGCAGCTGCCGCCGCATCCGCGCAATGACGAAATCGGCGAGCTGATTTCCGCGTTCGGGCGCATGAGCGAAAGCATTGC
CCGGCACGATCGCGAGGTGCGCCACATGGCCTACACCGACGCGCTGACCGGGCTGACCAACCGCCTGGGCTTCCGCGAAG
GCCTGGACCATCTGCTGCACACCGCACGCAGTACCGACAGCAAGCTGGCGCTGTTGTTCGCCGACATCGACGACTTCAAA
CGGGTCAACGACACCCTGGGCCACGAGGCCGGCGACGAGGCGCTGCTGCAGTTCTCCAGCCGCATCAGCCGTGCGGTGGC
GGCACTGGGCGGCGATGACGCCATCCTGGCGCGGTTTGGCGGCGACGAGTTCGTGATCCTGCTGCAGAGTGGCGATGTGA
CCTTGCTCGCCGCGCAGCTGGCCGACCGCCTGGTGCATGAGTTGAGCCGCCCGTTGAACGTGCAGGGACGCGAGGTGTTT
TTGGGCACGTCGATCGGCATCACCTTGTTCCCGGACGATGCCAACGACGCCACGGCGCTGCTGAAAAACGGCGACATCGC
GATGTACCAGGCCAAGGTGGCCGGCAAGAACTGCCACCGGTTCTACAGCCGCGCAGCCGACCATGCGGTGGAGCGCCGCG
TGCACATGGAACACGAGTTGCGCGGTGCCTGGGAGCGCGACGAATTACGCCTGGTCTATCAGCCGATCTACCGCACCAGC
GACCGCGTGCTGGTGGGCGTGGAAGTGTTGCTGCGCTGGCAGCACCCGGCGTTGGGCACGATTCCGCCGTCCACGTTCAT
TGATATTGCAGAGCAGAGTGGGCTGATCGAAGTGATCGGGCCCAAGGTGCTGCGTGCGGCCTGCCTGGAAGCGGCCAAAT
GGCCGGTGGTGGGCGAGGGCTTGTTCATTTCGGTCAACGTCTCGCCGCGCCAGCTGCGCAGTGGCGACCTGATCGACACC
GTGGCCGAGTGCCTGGCCGAATCCGGCCTGCCGGCCGCGCGCCTGCATCTGGAGCTCACCGAGACCGCGGTGATCGGCGA
CGAGATGATGGCTGCAAGCCTGCTCGATCAATTGCACCGCACCGGGGTGAAGGTGTGGCTGGACGATTTCGGCACCGGCT
TCTCCGGCCTGAGCCATCTGCGTCAGGTGCCGGTGGATGGCGTCAAGATCGACAAGAGCTTCATCGCCGACCTGCAGCGC
GACCCCGACGACCTGGCCCTGACCACGGCCATCATCGGCATGGCGCATTCGCTGGGGATCACCGTGGTGGCCGAGGGCAT
CGAGCAGGAAGCGCAGTTCAACCTGTTGCGCGACCGCGGCTGCGACCTGGGCCAGGGCTACTGGTTCAGCCGCCCACTGA
GCCCGGCTGACATGGTCAAGCTGATCGCGGCGGGCTGA

Upstream 100 bases:

>100_bases
GCTTTTTCGGCACCACGGCGTTCCATCCCGTGGACGCGCCCAGCCGCGCGCGCCTGGAGGCGTTGCGCAATGGGCTGCAA
CAGGTCAGGACCCAGGTGGA

Downstream 100 bases:

>100_bases
CGAGTGCCTCCACCGGCTTGATTGCAGCGTCTGTTCTTGGCGTCGCCTATACGATTGCGGGGGCAGTGCGGCTAGCTACG
TAGAGCGCACCTGTGCGCGA

Product: GGDEF family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 705; Mature: 704

Protein sequence:

>705_residues
MTQVRFGLQARFLLVMALTLLLVGAILASLLQRQSSMQREVRSLSAQILHELFDRSLRTRGETLATELASGLANPLYYSD
LAAVGALVRNASRQQVVSYVRVFDRRGRLVHDGSATLQGYGQPMQDPLAAKAIAAPALLLQSSPEVLDVTVPIKVGDQRI
GGVRVGMSRERVRKIESSANLTLVQNLNAIGKRDLGWLLVLLAALVALGILLAIYVQRTLVAPVRLLAAAARQIERGDYL
VQLPPHPRNDEIGELISAFGRMSESIARHDREVRHMAYTDALTGLTNRLGFREGLDHLLHTARSTDSKLALLFADIDDFK
RVNDTLGHEAGDEALLQFSSRISRAVAALGGDDAILARFGGDEFVILLQSGDVTLLAAQLADRLVHELSRPLNVQGREVF
LGTSIGITLFPDDANDATALLKNGDIAMYQAKVAGKNCHRFYSRAADHAVERRVHMEHELRGAWERDELRLVYQPIYRTS
DRVLVGVEVLLRWQHPALGTIPPSTFIDIAEQSGLIEVIGPKVLRAACLEAAKWPVVGEGLFISVNVSPRQLRSGDLIDT
VAECLAESGLPAARLHLELTETAVIGDEMMAASLLDQLHRTGVKVWLDDFGTGFSGLSHLRQVPVDGVKIDKSFIADLQR
DPDDLALTTAIIGMAHSLGITVVAEGIEQEAQFNLLRDRGCDLGQGYWFSRPLSPADMVKLIAAG

Sequences:

>Translated_705_residues
MTQVRFGLQARFLLVMALTLLLVGAILASLLQRQSSMQREVRSLSAQILHELFDRSLRTRGETLATELASGLANPLYYSD
LAAVGALVRNASRQQVVSYVRVFDRRGRLVHDGSATLQGYGQPMQDPLAAKAIAAPALLLQSSPEVLDVTVPIKVGDQRI
GGVRVGMSRERVRKIESSANLTLVQNLNAIGKRDLGWLLVLLAALVALGILLAIYVQRTLVAPVRLLAAAARQIERGDYL
VQLPPHPRNDEIGELISAFGRMSESIARHDREVRHMAYTDALTGLTNRLGFREGLDHLLHTARSTDSKLALLFADIDDFK
RVNDTLGHEAGDEALLQFSSRISRAVAALGGDDAILARFGGDEFVILLQSGDVTLLAAQLADRLVHELSRPLNVQGREVF
LGTSIGITLFPDDANDATALLKNGDIAMYQAKVAGKNCHRFYSRAADHAVERRVHMEHELRGAWERDELRLVYQPIYRTS
DRVLVGVEVLLRWQHPALGTIPPSTFIDIAEQSGLIEVIGPKVLRAACLEAAKWPVVGEGLFISVNVSPRQLRSGDLIDT
VAECLAESGLPAARLHLELTETAVIGDEMMAASLLDQLHRTGVKVWLDDFGTGFSGLSHLRQVPVDGVKIDKSFIADLQR
DPDDLALTTAIIGMAHSLGITVVAEGIEQEAQFNLLRDRGCDLGQGYWFSRPLSPADMVKLIAAG
>Mature_704_residues
TQVRFGLQARFLLVMALTLLLVGAILASLLQRQSSMQREVRSLSAQILHELFDRSLRTRGETLATELASGLANPLYYSDL
AAVGALVRNASRQQVVSYVRVFDRRGRLVHDGSATLQGYGQPMQDPLAAKAIAAPALLLQSSPEVLDVTVPIKVGDQRIG
GVRVGMSRERVRKIESSANLTLVQNLNAIGKRDLGWLLVLLAALVALGILLAIYVQRTLVAPVRLLAAAARQIERGDYLV
QLPPHPRNDEIGELISAFGRMSESIARHDREVRHMAYTDALTGLTNRLGFREGLDHLLHTARSTDSKLALLFADIDDFKR
VNDTLGHEAGDEALLQFSSRISRAVAALGGDDAILARFGGDEFVILLQSGDVTLLAAQLADRLVHELSRPLNVQGREVFL
GTSIGITLFPDDANDATALLKNGDIAMYQAKVAGKNCHRFYSRAADHAVERRVHMEHELRGAWERDELRLVYQPIYRTSD
RVLVGVEVLLRWQHPALGTIPPSTFIDIAEQSGLIEVIGPKVLRAACLEAAKWPVVGEGLFISVNVSPRQLRSGDLIDTV
AECLAESGLPAARLHLELTETAVIGDEMMAASLLDQLHRTGVKVWLDDFGTGFSGLSHLRQVPVDGVKIDKSFIADLQRD
PDDLALTTAIIGMAHSLGITVVAEGIEQEAQFNLLRDRGCDLGQGYWFSRPLSPADMVKLIAAG

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=431, Percent_Identity=35.4988399071926, Blast_Score=265, Evalue=7e-72,
Organism=Escherichia coli, GI87081921, Length=452, Percent_Identity=34.2920353982301, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI226510982, Length=523, Percent_Identity=29.0630975143403, Blast_Score=182, Evalue=9e-47,
Organism=Escherichia coli, GI87081845, Length=263, Percent_Identity=35.361216730038, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1788502, Length=306, Percent_Identity=31.6993464052288, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI1786507, Length=262, Percent_Identity=32.4427480916031, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1790496, Length=237, Percent_Identity=32.4894514767932, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI87081980, Length=257, Percent_Identity=33.4630350194552, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI1787055, Length=258, Percent_Identity=31.7829457364341, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI87081743, Length=250, Percent_Identity=32.4, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1788381, Length=423, Percent_Identity=29.7872340425532, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788849, Length=259, Percent_Identity=28.1853281853282, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1786584, Length=184, Percent_Identity=32.6086956521739, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082096, Length=247, Percent_Identity=27.1255060728745, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI87081977, Length=157, Percent_Identity=33.1210191082803, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788956, Length=159, Percent_Identity=36.4779874213836, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI145693134, Length=204, Percent_Identity=30.8823529411765, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787262, Length=172, Percent_Identity=31.3953488372093, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1787802, Length=173, Percent_Identity=31.2138728323699, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI87082280, Length=244, Percent_Identity=26.2295081967213, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081881, Length=173, Percent_Identity=30.635838150289, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1789650, Length=511, Percent_Identity=22.1135029354207, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI87082007, Length=164, Percent_Identity=29.2682926829268, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 76989; Mature: 76858

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50885 HAMP ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQVRFGLQARFLLVMALTLLLVGAILASLLQRQSSMQREVRSLSAQILHELFDRSLRTR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GETLATELASGLANPLYYSDLAAVGALVRNASRQQVVSYVRVFDRRGRLVHDGSATLQGY
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEECCCCHHCCC
GQPMQDPLAAKAIAAPALLLQSSPEVLDVTVPIKVGDQRIGGVRVGMSRERVRKIESSAN
CCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCEEECCCHHHHHHHHCCCC
LTLVQNLNAIGKRDLGWLLVLLAALVALGILLAIYVQRTLVAPVRLLAAAARQIERGDYL
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VQLPPHPRNDEIGELISAFGRMSESIARHDREVRHMAYTDALTGLTNRLGFREGLDHLLH
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
TARSTDSKLALLFADIDDFKRVNDTLGHEAGDEALLQFSSRISRAVAALGGDDAILARFG
HHCCCCCCEEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
GDEFVILLQSGDVTLLAAQLADRLVHELSRPLNVQGREVFLGTSIGITLFPDDANDATAL
CCEEEEEEECCCEEHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEEECCCCCCCHHHH
LKNGDIAMYQAKVAGKNCHRFYSRAADHAVERRVHMEHELRGAWERDELRLVYQPIYRTS
HCCCCEEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
DRVLVGVEVLLRWQHPALGTIPPSTFIDIAEQSGLIEVIGPKVLRAACLEAAKWPVVGEG
CCEEEEEHHHHEECCCCCCCCCCHHHHHHHHCCCCEEHHCHHHHHHHHHHHHCCCEECCC
LFISVNVSPRQLRSGDLIDTVAECLAESGLPAARLHLELTETAVIGDEMMAASLLDQLHR
EEEEEECCHHHHCCCCHHHHHHHHHHHCCCCHHEEEEEEHHHHHHHHHHHHHHHHHHHHH
TGVKVWLDDFGTGFSGLSHLRQVPVDGVKIDKSFIADLQRDPDDLALTTAIIGMAHSLGI
CCCEEEEHHCCCCHHHHHHHHHCCCCCEEECHHHHHHHHCCCHHHHHHHHHHHHHHHCCH
TVVAEGIEQEAQFNLLRDRGCDLGQGYWFSRPLSPADMVKLIAAG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TQVRFGLQARFLLVMALTLLLVGAILASLLQRQSSMQREVRSLSAQILHELFDRSLRTR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GETLATELASGLANPLYYSDLAAVGALVRNASRQQVVSYVRVFDRRGRLVHDGSATLQGY
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEECCCCHHCCC
GQPMQDPLAAKAIAAPALLLQSSPEVLDVTVPIKVGDQRIGGVRVGMSRERVRKIESSAN
CCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCEEECCCHHHHHHHHCCCC
LTLVQNLNAIGKRDLGWLLVLLAALVALGILLAIYVQRTLVAPVRLLAAAARQIERGDYL
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VQLPPHPRNDEIGELISAFGRMSESIARHDREVRHMAYTDALTGLTNRLGFREGLDHLLH
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
TARSTDSKLALLFADIDDFKRVNDTLGHEAGDEALLQFSSRISRAVAALGGDDAILARFG
HHCCCCCCEEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
GDEFVILLQSGDVTLLAAQLADRLVHELSRPLNVQGREVFLGTSIGITLFPDDANDATAL
CCEEEEEEECCCEEHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEEECCCCCCCHHHH
LKNGDIAMYQAKVAGKNCHRFYSRAADHAVERRVHMEHELRGAWERDELRLVYQPIYRTS
HCCCCEEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
DRVLVGVEVLLRWQHPALGTIPPSTFIDIAEQSGLIEVIGPKVLRAACLEAAKWPVVGEG
CCEEEEEHHHHEECCCCCCCCCCHHHHHHHHCCCCEEHHCHHHHHHHHHHHHCCCEECCC
LFISVNVSPRQLRSGDLIDTVAECLAESGLPAARLHLELTETAVIGDEMMAASLLDQLHR
EEEEEECCHHHHCCCCHHHHHHHHHHHCCCCHHEEEEEEHHHHHHHHHHHHHHHHHHHHH
TGVKVWLDDFGTGFSGLSHLRQVPVDGVKIDKSFIADLQRDPDDLALTTAIIGMAHSLGI
CCCEEEEHHCCCCHHHHHHHHHCCCCCEEECHHHHHHHHCCCHHHHHHHHHHHHHHHCCH
TVVAEGIEQEAQFNLLRDRGCDLGQGYWFSRPLSPADMVKLIAAG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]