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The map label for this gene is ykoU [H]

Identifier: 66768129

GI number: 66768129

Start: 2195931

End: 2198480

Strand: Direct

Name: ykoU [H]

Synonym: XC_1808

Alternate gene names: 66768129

Gene position: 2195931-2198480 (Clockwise)

Preceding gene: 66768128

Following gene: 77761168

Centisome position: 42.65

GC content: 66.12

Gene sequence:

>2550_bases
ATGAGCCTGAGTGAATACCGCCGCAAGCGCAGCTTCGACAAGACCCGCGAGCCGGAGCCAGGCAAGTTGCTGCCGCAAGG
GCAGCGGGCGATCTTCGTGGTGCAGCTGCACCATGCCAGCCGGCGCCACTACGATTTCCGCTTGCAGGTGGGCGATGCGC
TCAAGAGCTGGGCGGTGCCGAAGGGGCCAAGCTACGACCCGGCAGTCAAGCGCATGGCGGTAGAGGTGGAAGACCACCCG
GTGGACTATGCCAGTTTCGAAGGCGAGATTCCGAAGGGCGAATACGGCGGCGGCCACGTGGCTCAGTTCGATCATGGGGT
CTGGGCCACCGCCGGTGACCCGGAAGCGCAGTTGGCCAAGGGCCACCTGCGCTTCGAGTTGTTCGGCAGCAAGCTCAAGG
GCGGCTGGCACCTGGTGCGCTCGAGCAAGCCGGCCCGCCAGCCGCAGTGGTTGCTGTTCAAGGAGGACGACGCCTATGCC
GGCACGCTGGAAGCCGACGATCTGCTGGCCGATGTGGCTGCGGCGCCAGCAGAAGATGTACGTCGCGCCGGTGCCGGCAA
GGCCCAACGCAAGGCACTCACCACCGTGCCTGTGCCCCGGGCGCGCGCACGTAACGCCTGGACCAACGCCGCGTTGAAAC
TCACGCACGCGCGGCGCGGCGACATCGACGATGCCGCGTTCGCACCGCAGCTGGCCAAGCTCGGGCAGGCGCCGCCGGAA
GGGGCGCAATGGGTGCATGAAATCAAGTGGGACGGTTATCGCATCCTGGCCACGGTGACCGATGGTCAGGTACGGCTGTG
GTCGCGCAATGCGCTGGAATGGACCGACAAGATTCCCGATATCCGCGATGCGATCCAGGCGCTCAACCTGCGCTCGGCAC
GGCTGGATGGCGAGCTGATCGCCGGGCGTGGCACCAAGGAGGATTTCAACCTGCTGCAGGCGACCTTGTCGGGCGAACGC
CAGGTGCCGCTGGCGCTGGCGGTGTTCGACCTGCTGCACATCGATGGCGTGGAGATCAGCGAGGCGCCGCTGCGCGAACG
CAAGCAGCTCTTGCAGCAGATCCTGGCGAATGCGCCGGCCGGCCATCTGGCCTACAGCTCGCATGTGGAGGGCGATGGGC
TGGAGGCGTTCCGGGTCGCCGGCGAGCAGCACTTCGAAGGCATCATTTCCAAGCGTGCCGACCGGCCGTACCGCGGCGGT
CGCAGCGATGATTGGCGCAAGACCAAGCAACTGGCCAGCCAGGAATACGCGGTCGTCGGCTATACCGCGCCCAAGGGCAG
CCGTACCGGCTTCGGCTCGCTGCTGCTGGCCACGCCGGACCCGCAGCACGGCTGGTTGTATGTGGGGCGGGTTGGTTCGG
GCTTTTCTGATACGTTGATGCAGGAGGTGACCCAGCACCTGCACGGGGGCGGCAAGCGGCCCACCGCGCATATCCCCACC
GAGGACACCGATCTGCGTGGCGCCACCTGGTTCGCGCCGCGGTTCGTGGTGGAGGTGTTCTATCGCGGCATCGGGGGGCA
GCAGCTGTTGCGCCAGGCCTCGCTCAAGGCGGTGCGTCTGGACAAGGACATCGCCGACCTGGCCGACAGCGATATGGGGG
ATGTCAGTCCCGCGCAGGCCGACGTGGCCGACACTCCAGCACGCGGGCGCAAGCGTGCAAACAAGCAAGCGCCCGCGCAG
GGCGAGCCCACGTTGTCCAGCCCGACCAAGCTGATCTACCCGGACATCCGCGCCACCAAGGGCGATGTCTGGGACTACTA
CCACGCGGTGATGGATCACCTGCTGCCAGAGATCGTGGGGCGGCCGTTGTCGATCATCCGTTGCCCCAATGGCGCGGAAA
AGCCGTGTTTCTTCCAGAAGCATCACACCGCCGGGCTGGAGCGGGTGAGCTCGGTGCGGTTGAAGGAAGAGACCGGCAGC
AATGCCTACTATCTGGTGGTCGAAGATGCGCCCGGGCTGCTGGAACTGGTGCAGTTCAATGCGCTGGAATTCCACCCCTG
GGGCTCGCATGCCGCGCGGCCGGACATGGCCGATCGCGTGGTGTTCGATCTGGATCCGGGCCCGGATGTGCCATTTGCCG
AGGTCAAACGGGCCGCCACCGATATCCGCAAGCTGCTGGCGCAGCTGGAGCTGGAATCGTTTCTGCGCGTCTCCGGTGGC
AAGGGCCTGCACGTGGTGGTGCCCTTGAATCCGGGCTGCGATTGGGAGTTGACCAAGCGCTTTGCCAAAGGCTTTGCCGA
CGCATTGGCGCAATCCGAGCCGGACCGCTTTGTGGCGACGGCAACCAAGCGCTTCCGCAACAAACGCATCTTTGTCGATT
ATCTGCGCAACGGGCGTGGGGCCACCGCAGTGGCGTCGTACTCGCTGCGCGGCCGCCCGGGCGCACCGGTGGCATTGCCG
CTGCCGTGGTCAGATTTGGCCAAGCTACATCGCGCCAACGCCTTCACCCTGCGCGATGTCCCAGACAAGTTGCGTCGCCG
CCGCAAGGACCCTTGGGCAGACATCGCGCAGATTCAACAGAACCTGGCGCGCTGGGCGGACCAGGGCTGA

Upstream 100 bases:

>100_bases
CCCTTGGCGTGAGCGCCGACGAACTGCGCGCGGCCGTGGATGCGGTGGGGCCGGTGGCCGCCAAGGTGCGCCAGCACCTG
GGCAAATAGGCCCGGCTTGC

Downstream 100 bases:

>100_bases
GGCACGTACTGCCTCTCACACAAGCACGCCGGATGCGTTGTTGCCGCACGCCGCCGCAGTCACGCGGCAAACGTGCGCAA
CACGCCGCTCAGGGCGTTGC

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 849; Mature: 848

Protein sequence:

>849_residues
MSLSEYRRKRSFDKTREPEPGKLLPQGQRAIFVVQLHHASRRHYDFRLQVGDALKSWAVPKGPSYDPAVKRMAVEVEDHP
VDYASFEGEIPKGEYGGGHVAQFDHGVWATAGDPEAQLAKGHLRFELFGSKLKGGWHLVRSSKPARQPQWLLFKEDDAYA
GTLEADDLLADVAAAPAEDVRRAGAGKAQRKALTTVPVPRARARNAWTNAALKLTHARRGDIDDAAFAPQLAKLGQAPPE
GAQWVHEIKWDGYRILATVTDGQVRLWSRNALEWTDKIPDIRDAIQALNLRSARLDGELIAGRGTKEDFNLLQATLSGER
QVPLALAVFDLLHIDGVEISEAPLRERKQLLQQILANAPAGHLAYSSHVEGDGLEAFRVAGEQHFEGIISKRADRPYRGG
RSDDWRKTKQLASQEYAVVGYTAPKGSRTGFGSLLLATPDPQHGWLYVGRVGSGFSDTLMQEVTQHLHGGGKRPTAHIPT
EDTDLRGATWFAPRFVVEVFYRGIGGQQLLRQASLKAVRLDKDIADLADSDMGDVSPAQADVADTPARGRKRANKQAPAQ
GEPTLSSPTKLIYPDIRATKGDVWDYYHAVMDHLLPEIVGRPLSIIRCPNGAEKPCFFQKHHTAGLERVSSVRLKEETGS
NAYYLVVEDAPGLLELVQFNALEFHPWGSHAARPDMADRVVFDLDPGPDVPFAEVKRAATDIRKLLAQLELESFLRVSGG
KGLHVVVPLNPGCDWELTKRFAKGFADALAQSEPDRFVATATKRFRNKRIFVDYLRNGRGATAVASYSLRGRPGAPVALP
LPWSDLAKLHRANAFTLRDVPDKLRRRRKDPWADIAQIQQNLARWADQG

Sequences:

>Translated_849_residues
MSLSEYRRKRSFDKTREPEPGKLLPQGQRAIFVVQLHHASRRHYDFRLQVGDALKSWAVPKGPSYDPAVKRMAVEVEDHP
VDYASFEGEIPKGEYGGGHVAQFDHGVWATAGDPEAQLAKGHLRFELFGSKLKGGWHLVRSSKPARQPQWLLFKEDDAYA
GTLEADDLLADVAAAPAEDVRRAGAGKAQRKALTTVPVPRARARNAWTNAALKLTHARRGDIDDAAFAPQLAKLGQAPPE
GAQWVHEIKWDGYRILATVTDGQVRLWSRNALEWTDKIPDIRDAIQALNLRSARLDGELIAGRGTKEDFNLLQATLSGER
QVPLALAVFDLLHIDGVEISEAPLRERKQLLQQILANAPAGHLAYSSHVEGDGLEAFRVAGEQHFEGIISKRADRPYRGG
RSDDWRKTKQLASQEYAVVGYTAPKGSRTGFGSLLLATPDPQHGWLYVGRVGSGFSDTLMQEVTQHLHGGGKRPTAHIPT
EDTDLRGATWFAPRFVVEVFYRGIGGQQLLRQASLKAVRLDKDIADLADSDMGDVSPAQADVADTPARGRKRANKQAPAQ
GEPTLSSPTKLIYPDIRATKGDVWDYYHAVMDHLLPEIVGRPLSIIRCPNGAEKPCFFQKHHTAGLERVSSVRLKEETGS
NAYYLVVEDAPGLLELVQFNALEFHPWGSHAARPDMADRVVFDLDPGPDVPFAEVKRAATDIRKLLAQLELESFLRVSGG
KGLHVVVPLNPGCDWELTKRFAKGFADALAQSEPDRFVATATKRFRNKRIFVDYLRNGRGATAVASYSLRGRPGAPVALP
LPWSDLAKLHRANAFTLRDVPDKLRRRRKDPWADIAQIQQNLARWADQG
>Mature_848_residues
SLSEYRRKRSFDKTREPEPGKLLPQGQRAIFVVQLHHASRRHYDFRLQVGDALKSWAVPKGPSYDPAVKRMAVEVEDHPV
DYASFEGEIPKGEYGGGHVAQFDHGVWATAGDPEAQLAKGHLRFELFGSKLKGGWHLVRSSKPARQPQWLLFKEDDAYAG
TLEADDLLADVAAAPAEDVRRAGAGKAQRKALTTVPVPRARARNAWTNAALKLTHARRGDIDDAAFAPQLAKLGQAPPEG
AQWVHEIKWDGYRILATVTDGQVRLWSRNALEWTDKIPDIRDAIQALNLRSARLDGELIAGRGTKEDFNLLQATLSGERQ
VPLALAVFDLLHIDGVEISEAPLRERKQLLQQILANAPAGHLAYSSHVEGDGLEAFRVAGEQHFEGIISKRADRPYRGGR
SDDWRKTKQLASQEYAVVGYTAPKGSRTGFGSLLLATPDPQHGWLYVGRVGSGFSDTLMQEVTQHLHGGGKRPTAHIPTE
DTDLRGATWFAPRFVVEVFYRGIGGQQLLRQASLKAVRLDKDIADLADSDMGDVSPAQADVADTPARGRKRANKQAPAQG
EPTLSSPTKLIYPDIRATKGDVWDYYHAVMDHLLPEIVGRPLSIIRCPNGAEKPCFFQKHHTAGLERVSSVRLKEETGSN
AYYLVVEDAPGLLELVQFNALEFHPWGSHAARPDMADRVVFDLDPGPDVPFAEVKRAATDIRKLLAQLELESFLRVSGGK
GLHVVVPLNPGCDWELTKRFAKGFADALAQSEPDRFVATATKRFRNKRIFVDYLRNGRGATAVASYSLRGRPGAPVALPL
PWSDLAKLHRANAFTLRDVPDKLRRRRKDPWADIAQIQQNLARWADQG

Specific function: Probably involved in the repair of DNA double-strand breaks by non-homologous-end joining (NHEJ) during spore germination [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Homo sapiens, GI4557719, Length=257, Percent_Identity=28.4046692607004, Blast_Score=79, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320038, Length=312, Percent_Identity=26.6025641025641, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR014145
- InterPro:   IPR014143 [H]

Pfam domain/function: PF01068 DNA_ligase_A_M [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 93977; Mature: 93846

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSEYRRKRSFDKTREPEPGKLLPQGQRAIFVVQLHHASRRHYDFRLQVGDALKSWAVP
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEEECHHHHHCCCC
KGPSYDPAVKRMAVEVEDHPVDYASFEGEIPKGEYGGGHVAQFDHGVWATAGDPEAQLAK
CCCCCCHHHHHEEEEECCCCCCHHHCCCCCCCCCCCCCEEEEECCCEEECCCCCHHHHHH
GHLRFELFGSKLKGGWHLVRSSKPARQPQWLLFKEDDAYAGTLEADDLLADVAAAPAEDV
CCEEEEEECCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCHHHH
RRAGAGKAQRKALTTVPVPRARARNAWTNAALKLTHARRGDIDDAAFAPQLAKLGQAPPE
HHCCCCHHHHCEECCCCCCCHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCC
GAQWVHEIKWDGYRILATVTDGQVRLWSRNALEWTDKIPDIRDAIQALNLRSARLDGELI
HHHHHHHHCCCCEEEEEEEECCEEEEEECCCHHHHHCCCCHHHHHHHHHHHHHCCCCEEE
AGRGTKEDFNLLQATLSGERQVPLALAVFDLLHIDGVEISEAPLRERKQLLQQILANAPA
ECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCC
GHLAYSSHVEGDGLEAFRVAGEQHFEGIISKRADRPYRGGRSDDWRKTKQLASQEYAVVG
CCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEE
YTAPKGSRTGFGSLLLATPDPQHGWLYVGRVGSGFSDTLMQEVTQHLHGGGKRPTAHIPT
EECCCCCCCCCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
EDTDLRGATWFAPRFVVEVFYRGIGGQQLLRQASLKAVRLDKDIADLADSDMGDVSPAQA
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCC
DVADTPARGRKRANKQAPAQGEPTLSSPTKLIYPDIRATKGDVWDYYHAVMDHLLPEIVG
CCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHC
RPLSIIRCPNGAEKPCFFQKHHTAGLERVSSVRLKEETGSNAYYLVVEDAPGLLELVQFN
CCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHCC
ALEFHPWGSHAARPDMADRVVFDLDPGPDVPFAEVKRAATDIRKLLAQLELESFLRVSGG
CEEECCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KGLHVVVPLNPGCDWELTKRFAKGFADALAQSEPDRFVATATKRFRNKRIFVDYLRNGRG
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEHHHCCCC
ATAVASYSLRGRPGAPVALPLPWSDLAKLHRANAFTLRDVPDKLRRRRKDPWADIAQIQQ
CEEEEEEEECCCCCCCEEEECCHHHHHHHHHCCCEEECCCHHHHHHHCCCCHHHHHHHHH
NLARWADQG
HHHHHHCCC
>Mature Secondary Structure 
SLSEYRRKRSFDKTREPEPGKLLPQGQRAIFVVQLHHASRRHYDFRLQVGDALKSWAVP
CHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEEECHHHHHCCCC
KGPSYDPAVKRMAVEVEDHPVDYASFEGEIPKGEYGGGHVAQFDHGVWATAGDPEAQLAK
CCCCCCHHHHHEEEEECCCCCCHHHCCCCCCCCCCCCCEEEEECCCEEECCCCCHHHHHH
GHLRFELFGSKLKGGWHLVRSSKPARQPQWLLFKEDDAYAGTLEADDLLADVAAAPAEDV
CCEEEEEECCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCHHHH
RRAGAGKAQRKALTTVPVPRARARNAWTNAALKLTHARRGDIDDAAFAPQLAKLGQAPPE
HHCCCCHHHHCEECCCCCCCHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCC
GAQWVHEIKWDGYRILATVTDGQVRLWSRNALEWTDKIPDIRDAIQALNLRSARLDGELI
HHHHHHHHCCCCEEEEEEEECCEEEEEECCCHHHHHCCCCHHHHHHHHHHHHHCCCCEEE
AGRGTKEDFNLLQATLSGERQVPLALAVFDLLHIDGVEISEAPLRERKQLLQQILANAPA
ECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCC
GHLAYSSHVEGDGLEAFRVAGEQHFEGIISKRADRPYRGGRSDDWRKTKQLASQEYAVVG
CCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEE
YTAPKGSRTGFGSLLLATPDPQHGWLYVGRVGSGFSDTLMQEVTQHLHGGGKRPTAHIPT
EECCCCCCCCCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
EDTDLRGATWFAPRFVVEVFYRGIGGQQLLRQASLKAVRLDKDIADLADSDMGDVSPAQA
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCC
DVADTPARGRKRANKQAPAQGEPTLSSPTKLIYPDIRATKGDVWDYYHAVMDHLLPEIVG
CCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHC
RPLSIIRCPNGAEKPCFFQKHHTAGLERVSSVRLKEETGSNAYYLVVEDAPGLLELVQFN
CCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHCC
ALEFHPWGSHAARPDMADRVVFDLDPGPDVPFAEVKRAATDIRKLLAQLELESFLRVSGG
CEEECCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KGLHVVVPLNPGCDWELTKRFAKGFADALAQSEPDRFVATATKRFRNKRIFVDYLRNGRG
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEHHHCCCC
ATAVASYSLRGRPGAPVALPLPWSDLAKLHRANAFTLRDVPDKLRRRRKDPWADIAQIQQ
CEEEEEEEECCCCCCCEEEECCHHHHHHHHHCCCEEECCCHHHHHHHCCCCHHHHHHHHH
NLARWADQG
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]