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The map label for this gene is 66768121

Identifier: 66768121

GI number: 66768121

Start: 2188616

End: 2189239

Strand: Reverse

Name: 66768121

Synonym: XC_1800

Alternate gene names: NA

Gene position: 2189239-2188616 (Counterclockwise)

Preceding gene: 66768124

Following gene: 66768119

Centisome position: 42.52

GC content: 65.06

Gene sequence:

>624_bases
ATGTCATTGCACTCGCCTTTGCCGCGCGCTTTTTATGCAGCCGATGCGCGCACCGTTGCGCCACTGCTACTCAACAAGGT
TCTGGTGAGTGCCGACGGCCGCCGCGGCCGCATCACCGAAGTCGAAGCGTATTGCGGCAGCGAAGATGCCGCTGCGCATT
CGTTTCGCGGCATGACCCCACGCACGCAGGTGATGTTCGGTGCGCCCGGGCATTTGTATGTGTATTTCATCTACGGCATG
CACTGGGCAATCAACGCGGTATGTGGCGGCGCGCCCGGGCACGCAGTGTTGATCCGTGCGCTGGAACCGTTGGCCGGCTG
CGATGCGATGCACGCTGCACGCGGCGCAGCGCCGTTCAAATCGTTGACCACCGGTCCAGGCCGCCTGGCGCAAGCCTTTG
GCGTGAGCGCAGTCGATAACGGACTGGACCTGACCACTGGCGTGGCGCGCTTGTGGATCGAGGACGACGGCACTCCGTCA
CCAGCGGCACCGCTTGCCGGCCCGCGCATCGGCATTCGCAAGGCCGTGGAATTGCCGTGGCGCTGGGTTGTGCCTGGCAG
CGCCTATCTGTCGCGTCCGCTGCCACGTGTGAGCGGCGCACGCGCATCAGTAACCGGCGACTGA

Upstream 100 bases:

>100_bases
CTTGCCGCGCGCCCCATTCGGAAAATCCCTACCCGCGTTATGCACGCTGTCCGGGACAGTCCCGCAGAGACATCACAACC
ACCGCGTTAGGCTTGCGCGC

Downstream 100 bases:

>100_bases
GCGAGCCATTGCTGCAGTGGCGTCTGCTCGGCGGCGCCCGGCCCACGTTGCAGCAATCGCAATGCCTGCTCGCCGTGCTC
GTGTGAGAGCTCTTGCAGCG

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSLHSPLPRAFYAADARTVAPLLLNKVLVSADGRRGRITEVEAYCGSEDAAAHSFRGMTPRTQVMFGAPGHLYVYFIYGM
HWAINAVCGGAPGHAVLIRALEPLAGCDAMHAARGAAPFKSLTTGPGRLAQAFGVSAVDNGLDLTTGVARLWIEDDGTPS
PAAPLAGPRIGIRKAVELPWRWVVPGSAYLSRPLPRVSGARASVTGD

Sequences:

>Translated_207_residues
MSLHSPLPRAFYAADARTVAPLLLNKVLVSADGRRGRITEVEAYCGSEDAAAHSFRGMTPRTQVMFGAPGHLYVYFIYGM
HWAINAVCGGAPGHAVLIRALEPLAGCDAMHAARGAAPFKSLTTGPGRLAQAFGVSAVDNGLDLTTGVARLWIEDDGTPS
PAAPLAGPRIGIRKAVELPWRWVVPGSAYLSRPLPRVSGARASVTGD
>Mature_206_residues
SLHSPLPRAFYAADARTVAPLLLNKVLVSADGRRGRITEVEAYCGSEDAAAHSFRGMTPRTQVMFGAPGHLYVYFIYGMH
WAINAVCGGAPGHAVLIRALEPLAGCDAMHAARGAAPFKSLTTGPGRLAQAFGVSAVDNGLDLTTGVARLWIEDDGTPSP
AAPLAGPRIGIRKAVELPWRWVVPGSAYLSRPLPRVSGARASVTGD

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family

Homologues:

Organism=Homo sapiens, GI62632769, Length=158, Percent_Identity=39.873417721519, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI62632771, Length=158, Percent_Identity=39.873417721519, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI62632765, Length=158, Percent_Identity=39.873417721519, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 3MGH_XANC8 (Q4UVR0)

Other databases:

- EMBL:   CP000050
- RefSeq:   YP_242883.1
- HSSP:   P29372
- ProteinModelPortal:   Q4UVR0
- SMR:   Q4UVR0
- STRING:   Q4UVR0
- GeneID:   3380347
- GenomeReviews:   CP000050_GR
- KEGG:   xcb:XC_1800
- eggNOG:   COG2094
- HOGENOM:   HBG664239
- OMA:   CANIVCG
- ProtClustDB:   PRK00802
- BioCyc:   XCAM314565:XC_1800-MONOMER
- HAMAP:   MF_00527
- InterPro:   IPR011034
- InterPro:   IPR003180
- Gene3D:   G3DSA:3.10.300.10
- PANTHER:   PTHR10429
- TIGRFAMs:   TIGR00567

Pfam domain/function: PF02245 Pur_DNA_glyco; SSF50486 FMT_C_like

EC number: 3.2.2.-

Molecular weight: Translated: 21755; Mature: 21624

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLHSPLPRAFYAADARTVAPLLLNKVLVSADGRRGRITEVEAYCGSEDAAAHSFRGMTP
CCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEHHHCCCCCHHHHHHCCCCC
RTQVMFGAPGHLYVYFIYGMHWAINAVCGGAPGHAVLIRALEPLAGCDAMHAARGAAPFK
CCEEEECCCCCEEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCHH
SLTTGPGRLAQAFGVSAVDNGLDLTTGVARLWIEDDGTPSPAAPLAGPRIGIRKAVELPW
HCCCCCHHHHHHHCCHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCE
RWVVPGSAYLSRPLPRVSGARASVTGD
EEECCCHHHHHCCCCCCCCCCEECCCC
>Mature Secondary Structure 
SLHSPLPRAFYAADARTVAPLLLNKVLVSADGRRGRITEVEAYCGSEDAAAHSFRGMTP
CCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEHHHCCCCCHHHHHHCCCCC
RTQVMFGAPGHLYVYFIYGMHWAINAVCGGAPGHAVLIRALEPLAGCDAMHAARGAAPFK
CCEEEECCCCCEEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCHH
SLTTGPGRLAQAFGVSAVDNGLDLTTGVARLWIEDDGTPSPAAPLAGPRIGIRKAVELPW
HCCCCCHHHHHHHCCHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCE
RWVVPGSAYLSRPLPRVSGARASVTGD
EEECCCHHHHHCCCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA