Click here to switch to the map view.

The map label for this gene is ygjG [C]

Identifier: 66768092

GI number: 66768092

Start: 2153782

End: 2155164

Strand: Direct

Name: ygjG [C]

Synonym: XC_1771

Alternate gene names: 66768092

Gene position: 2153782-2155164 (Clockwise)

Preceding gene: 66768091

Following gene: 66768093

Centisome position: 41.83

GC content: 66.09

Gene sequence:

>1383_bases
ATGTCGGAGCGGGTCGTGGATCCTTCTGTGCTCAGGTCCCTGCAGCAACTCGATGCTGCGCATCATCTGCATCCGTTCAA
TGACAACGCGGCACTGGCCTCCAAGGGCACGCGCATCCTGACGCGGGGCGAGGGGGTGTATGTGTGGGATGCGGATGGCA
ACAAGTTGCTGGATGCGTTTGCCGGGCTGTGGTGCGTCAACTTGGGCTATGGGCGGGCCGAGCTTGCGCAGGCGGCGGCG
CGGCAGATGGAGCAGTTGGCGTACTACAACAGCTTCTTTCAATGCACCACCGAGCCCACCGTGCACCTGGCTGCCAAGTT
GGCGGAGCTGGCGCCGGGCGATTTGAATCATGCGTTCTTTGCCAATTCCGGCTCGGAGGCCAACGACACCATCCTGCGGC
TGGTGCGGCATTTCTGGGCGGTGCAGGGGCAGCCGCAGAAGCACATCTTCATCGGCCGCCACGATGGCTACCACGGCACC
ACCATGGGTGGGGCCAGTCTGGGCGGAATGCGCGGGATGCATCGGCAAGGTGGGTTGCCGATTCCGGGGATCGAGCACAT
CGCGCCACCCAATCATTTCGGCGAGGGTGGCGAGATGGACCCGGACGACTACGGTCTGCTCGCTGCGCGCCGGCTGGAAG
AGAAGATCCTGCAGTTGGGGCCCGACACCGTGGCGGCCTTTATCGGTGAGCCGATCATGGGCGCGATCGGGGTCTACATC
CCACCGCGCAGCTACTGGCCGGAAATCGAACGCATCTGCCGGCGCTACGACGTACTGCTGGTGGCCGACGAGGTGATCTG
CGGGTTCGGCCGCACCGGTGCCTGGTTCGGCGCGGAGTATTTCGGTTTCCAGCCCGATGTGATGACCCTGGCCAAGGGCA
TCACTTCCGGCTACATCCCGCTGGCCGCGGCGATGTTCAACGACCGCGTAGCCGGTGTGCTCAAGCGTCAGGGCGGTGAA
CTGGCGCACGGCGGTACCTATGCCGGGCATCCGGTCTGCGCTGCGGTGGCGCTGGAAAACCTGCGGCTACTGCAGGACGA
GGGCATCGTGGACACCGCACGCACGCAGATTGCGCCGTACCTGGCGCAGCGCTGGGCCGAACTGGGCGCGCACCGTCTGG
TGGGCGAGGCGCGCATCGCCGGGCTGGTCGGTGCGCTGGAGCTGGTGCCCGACAAGCGCCGCCGTGGTGTGTACTTCCCG
GAGCGCGGGCGCGTAGGCGCGCTGTGCCGCGACTTTGCCCTGCGGCGCGGGCTGATCCTGCGGGCCACTTACGACGCCAT
GCTGCTGTCGCCGCCGTTGATCATCACCTGCGAACAGGTCGATGAGCTGTTCGACAAAACCTGGGCCGCGCTGGACGACA
CCGCGCAGGCGCTGGGCAAGTAA

Upstream 100 bases:

>100_bases
GCAAGGCAAAGCAGGGCAAGGTAGTTCTTGTGTCGCCATGCATGCCTGTGCGCTCCATCCACGGCATGGCAACAGTGCGC
GGGTATGCTCGTTGTTTCTC

Downstream 100 bases:

>100_bases
GCGCGGCGGCAGGCCTCACGCCGCCGAGCTGCGCAGCCACGACGCAGCGAGCGCCACCGCCGCAGTGAGCTTTGCCGTCC
CCGACGCTGCAGCGCATCGC

Product: putative aminotransferase

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MSERVVDPSVLRSLQQLDAAHHLHPFNDNAALASKGTRILTRGEGVYVWDADGNKLLDAFAGLWCVNLGYGRAELAQAAA
RQMEQLAYYNSFFQCTTEPTVHLAAKLAELAPGDLNHAFFANSGSEANDTILRLVRHFWAVQGQPQKHIFIGRHDGYHGT
TMGGASLGGMRGMHRQGGLPIPGIEHIAPPNHFGEGGEMDPDDYGLLAARRLEEKILQLGPDTVAAFIGEPIMGAIGVYI
PPRSYWPEIERICRRYDVLLVADEVICGFGRTGAWFGAEYFGFQPDVMTLAKGITSGYIPLAAAMFNDRVAGVLKRQGGE
LAHGGTYAGHPVCAAVALENLRLLQDEGIVDTARTQIAPYLAQRWAELGAHRLVGEARIAGLVGALELVPDKRRRGVYFP
ERGRVGALCRDFALRRGLILRATYDAMLLSPPLIITCEQVDELFDKTWAALDDTAQALGK

Sequences:

>Translated_460_residues
MSERVVDPSVLRSLQQLDAAHHLHPFNDNAALASKGTRILTRGEGVYVWDADGNKLLDAFAGLWCVNLGYGRAELAQAAA
RQMEQLAYYNSFFQCTTEPTVHLAAKLAELAPGDLNHAFFANSGSEANDTILRLVRHFWAVQGQPQKHIFIGRHDGYHGT
TMGGASLGGMRGMHRQGGLPIPGIEHIAPPNHFGEGGEMDPDDYGLLAARRLEEKILQLGPDTVAAFIGEPIMGAIGVYI
PPRSYWPEIERICRRYDVLLVADEVICGFGRTGAWFGAEYFGFQPDVMTLAKGITSGYIPLAAAMFNDRVAGVLKRQGGE
LAHGGTYAGHPVCAAVALENLRLLQDEGIVDTARTQIAPYLAQRWAELGAHRLVGEARIAGLVGALELVPDKRRRGVYFP
ERGRVGALCRDFALRRGLILRATYDAMLLSPPLIITCEQVDELFDKTWAALDDTAQALGK
>Mature_459_residues
SERVVDPSVLRSLQQLDAAHHLHPFNDNAALASKGTRILTRGEGVYVWDADGNKLLDAFAGLWCVNLGYGRAELAQAAAR
QMEQLAYYNSFFQCTTEPTVHLAAKLAELAPGDLNHAFFANSGSEANDTILRLVRHFWAVQGQPQKHIFIGRHDGYHGTT
MGGASLGGMRGMHRQGGLPIPGIEHIAPPNHFGEGGEMDPDDYGLLAARRLEEKILQLGPDTVAAFIGEPIMGAIGVYIP
PRSYWPEIERICRRYDVLLVADEVICGFGRTGAWFGAEYFGFQPDVMTLAKGITSGYIPLAAAMFNDRVAGVLKRQGGEL
AHGGTYAGHPVCAAVALENLRLLQDEGIVDTARTQIAPYLAQRWAELGAHRLVGEARIAGLVGALELVPDKRRRGVYFPE
RGRVGALCRDFALRRGLILRATYDAMLLSPPLIITCEQVDELFDKTWAALDDTAQALGK

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=431, Percent_Identity=28.0742459396752, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI4557809, Length=433, Percent_Identity=26.7898383371824, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI37574042, Length=432, Percent_Identity=27.5462962962963, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI226442705, Length=433, Percent_Identity=27.9445727482679, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI24119277, Length=432, Percent_Identity=26.8518518518519, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI226442709, Length=404, Percent_Identity=27.970297029703, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI284507298, Length=334, Percent_Identity=27.8443113772455, Blast_Score=103, Evalue=5e-22,
Organism=Escherichia coli, GI145693181, Length=406, Percent_Identity=28.3251231527094, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786991, Length=447, Percent_Identity=27.9642058165548, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI1789759, Length=405, Percent_Identity=26.9135802469136, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1788044, Length=418, Percent_Identity=28.4688995215311, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1789016, Length=419, Percent_Identity=26.491646778043, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1787560, Length=314, Percent_Identity=30.5732484076433, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786349, Length=351, Percent_Identity=25.0712250712251, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25144271, Length=426, Percent_Identity=26.2910798122066, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI71992977, Length=435, Percent_Identity=26.6666666666667, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI32564660, Length=440, Percent_Identity=27.0454545454545, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI25144274, Length=280, Percent_Identity=27.5, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323470, Length=466, Percent_Identity=24.8927038626609, Blast_Score=139, Evalue=8e-34,
Organism=Saccharomyces cerevisiae, GI6324386, Length=495, Percent_Identity=25.2525252525253, Blast_Score=123, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6324432, Length=423, Percent_Identity=25.0591016548463, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21356575, Length=417, Percent_Identity=30.6954436450839, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21357415, Length=431, Percent_Identity=27.3781902552204, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI161085790, Length=453, Percent_Identity=28.6975717439294, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI28574759, Length=466, Percent_Identity=27.8969957081545, Blast_Score=134, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 50166; Mature: 50035

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERVVDPSVLRSLQQLDAAHHLHPFNDNAALASKGTRILTRGEGVYVWDADGNKLLDAF
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEEECCEEEEECCCCHHHHHHH
AGLWCVNLGYGRAELAQAAARQMEQLAYYNSFFQCTTEPTVHLAAKLAELAPGDLNHAFF
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCCCCCCEE
ANSGSEANDTILRLVRHFWAVQGQPQKHIFIGRHDGYHGTTMGGASLGGMRGMHRQGGLP
ECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHCCCCC
IPGIEHIAPPNHFGEGGEMDPDDYGLLAARRLEEKILQLGPDTVAAFIGEPIMGAIGVYI
CCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHCEEE
PPRSYWPEIERICRRYDVLLVADEVICGFGRTGAWFGAEYFGFQPDVMTLAKGITSGYIP
CCCCCCHHHHHHHHHHCEEEEEHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHHCCCCHH
LAAAMFNDRVAGVLKRQGGELAHGGTYAGHPVCAAVALENLRLLQDEGIVDTARTQIAPY
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LAQRWAELGAHRLVGEARIAGLVGALELVPDKRRRGVYFPERGRVGALCRDFALRRGLIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHCCEEE
RATYDAMLLSPPLIITCEQVDELFDKTWAALDDTAQALGK
EEEHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SERVVDPSVLRSLQQLDAAHHLHPFNDNAALASKGTRILTRGEGVYVWDADGNKLLDAF
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEEECCEEEEECCCCHHHHHHH
AGLWCVNLGYGRAELAQAAARQMEQLAYYNSFFQCTTEPTVHLAAKLAELAPGDLNHAFF
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCCCCCCEE
ANSGSEANDTILRLVRHFWAVQGQPQKHIFIGRHDGYHGTTMGGASLGGMRGMHRQGGLP
ECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHCCCCC
IPGIEHIAPPNHFGEGGEMDPDDYGLLAARRLEEKILQLGPDTVAAFIGEPIMGAIGVYI
CCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHCEEE
PPRSYWPEIERICRRYDVLLVADEVICGFGRTGAWFGAEYFGFQPDVMTLAKGITSGYIP
CCCCCCHHHHHHHHHHCEEEEEHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHHCCCCHH
LAAAMFNDRVAGVLKRQGGELAHGGTYAGHPVCAAVALENLRLLQDEGIVDTARTQIAPY
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LAQRWAELGAHRLVGEARIAGLVGALELVPDKRRRGVYFPERGRVGALCRDFALRRGLIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHCCEEE
RATYDAMLLSPPLIITCEQVDELFDKTWAALDDTAQALGK
EEEHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]