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The map label for this gene is kdgR [H]

Identifier: 66768068

GI number: 66768068

Start: 2112787

End: 2113782

Strand: Direct

Name: kdgR [H]

Synonym: XC_1745

Alternate gene names: 66768068

Gene position: 2112787-2113782 (Clockwise)

Preceding gene: 66768062

Following gene: 66768072

Centisome position: 41.04

GC content: 68.78

Gene sequence:

>996_bases
GTGAGTATCAGCATCAATGACGTGGCCCGCGTGGCCGGGGTGTCCAAGTCCACGGTGTCGCGCGCCTTGGGCACCGGCCC
GGTGAGCGAAGAAGTGCGCGCCAAGGTGGAAGCTGCGGTGCGCCAGACCGGCTATCGCCCCAACCTGATGGCGCGGCGAT
TGCGATCCCAGCACTCCGGCATCCTCGGGGTGATCGTGGCCGACATCCGCAACCCGTACTTCACCGCGCTGATCCGTGCT
GTGGAAGAGGTCGCTTACAAGGCCGGTATGCGCGTGACCCTGTGCAATACCGATGAAGATCCCGAGCGCGAGGCGCTGTA
CCTGGAGCTGATGCAGGAAGAACGCATCACCGGGCTGATCTTCGCGCCCACCCGGGTCACGGTGGGGCGCATGCACGAGC
TGGTACTGGATTACCCCACCGTGCTGGTGGACCGCGCCGGTCCCGGCAGCCGCTACGACAGCGTGGTGCTGGACAACGCC
GCGGCCATGGCCGAACTGGTGGCGCATCTGCAGGCGCAGGGCTACCGCCGCATCGGCGGGTTGTTCGGCAGCACCAGCAC
TACCGCGGCCGAGCGCCGCGACGGCTACCTGGCAGCCATGCATGCCCAGGGCCTGGCACCGGACTACCGCGAGGTGGCAC
CCACCGCCGAGGCCGCGATTGCCGAACTGGAGCACTGGCTGGCCGCCGCCGACCGCCCCGAGGCCATCGTCACCAGTAAC
AGCCTGCTGCTGATGGGCGCATTGAAGGCCGCACGTACCGCCGGCCTGCGGCTGCCGCAGGACCTGGCGTTGGCGGGCTT
CGATAACGAGCGCTGGACCGATCTGGTCGAACCCGGCATCACCGTGGTCGAACAGCCGGTGGAGGACATGGGCCGCGCCG
CGATGTCGCTGCTGCTCGAACGCCTGGCCAGCCCGCAGCTGCCGATTCGCCGCATGGTGATGACCGGCCGCTGCGTGGTG
CGTGGCTCCACCGGCGCCCGCAGGCCGGGTATCTAA

Upstream 100 bases:

>100_bases
CAATGTGCGGTGCACAAAAACCCTGTAGTGCTTTCGGGTTAGCATCGGAATCGCAGGGCGCCTGGGTCCAGGTGCGCAAT
ATGGAGCGGGAACGGTCCCA

Downstream 100 bases:

>100_bases
CTGTCCCGAAGTAGCGCCAGCGCCGGCCCAAAATCCTGGCTCGTCGCGCGTGCGGTGCCCTCACCGCTCGCGGGACACGC
CGTGAACCCGTCCCTGGGGC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Kdg operon repressor [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSISINDVARVAGVSKSTVSRALGTGPVSEEVRAKVEAAVRQTGYRPNLMARRLRSQHSGILGVIVADIRNPYFTALIRA
VEEVAYKAGMRVTLCNTDEDPEREALYLELMQEERITGLIFAPTRVTVGRMHELVLDYPTVLVDRAGPGSRYDSVVLDNA
AAMAELVAHLQAQGYRRIGGLFGSTSTTAAERRDGYLAAMHAQGLAPDYREVAPTAEAAIAELEHWLAAADRPEAIVTSN
SLLLMGALKAARTAGLRLPQDLALAGFDNERWTDLVEPGITVVEQPVEDMGRAAMSLLLERLASPQLPIRRMVMTGRCVV
RGSTGARRPGI

Sequences:

>Translated_331_residues
MSISINDVARVAGVSKSTVSRALGTGPVSEEVRAKVEAAVRQTGYRPNLMARRLRSQHSGILGVIVADIRNPYFTALIRA
VEEVAYKAGMRVTLCNTDEDPEREALYLELMQEERITGLIFAPTRVTVGRMHELVLDYPTVLVDRAGPGSRYDSVVLDNA
AAMAELVAHLQAQGYRRIGGLFGSTSTTAAERRDGYLAAMHAQGLAPDYREVAPTAEAAIAELEHWLAAADRPEAIVTSN
SLLLMGALKAARTAGLRLPQDLALAGFDNERWTDLVEPGITVVEQPVEDMGRAAMSLLLERLASPQLPIRRMVMTGRCVV
RGSTGARRPGI
>Mature_330_residues
SISINDVARVAGVSKSTVSRALGTGPVSEEVRAKVEAAVRQTGYRPNLMARRLRSQHSGILGVIVADIRNPYFTALIRAV
EEVAYKAGMRVTLCNTDEDPEREALYLELMQEERITGLIFAPTRVTVGRMHELVLDYPTVLVDRAGPGSRYDSVVLDNAA
AMAELVAHLQAQGYRRIGGLFGSTSTTAAERRDGYLAAMHAQGLAPDYREVAPTAEAAIAELEHWLAAADRPEAIVTSNS
LLLMGALKAARTAGLRLPQDLALAGFDNERWTDLVEPGITVVEQPVEDMGRAAMSLLLERLASPQLPIRRMVMTGRCVVR
GSTGARRPGI

Specific function: Transcriptional repressor of the kdg operon for pectin utilization [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=329, Percent_Identity=33.1306990881459, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1790369, Length=329, Percent_Identity=31.306990881459, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1787948, Length=309, Percent_Identity=31.0679611650485, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1788474, Length=310, Percent_Identity=32.5806451612903, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1789202, Length=293, Percent_Identity=30.7167235494881, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789068, Length=299, Percent_Identity=29.4314381270903, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1787580, Length=324, Percent_Identity=29.6296296296296, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1787906, Length=339, Percent_Identity=28.9085545722714, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786268, Length=321, Percent_Identity=25.2336448598131, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI48994940, Length=305, Percent_Identity=29.8360655737705, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790689, Length=306, Percent_Identity=27.7777777777778, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790715, Length=311, Percent_Identity=26.3665594855305, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1786540, Length=308, Percent_Identity=25.3246753246753, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789456, Length=312, Percent_Identity=25, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35843; Mature: 35711

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISINDVARVAGVSKSTVSRALGTGPVSEEVRAKVEAAVRQTGYRPNLMARRLRSQHSG
CCCCHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
ILGVIVADIRNPYFTALIRAVEEVAYKAGMRVTLCNTDEDPEREALYLELMQEERITGLI
EEEEHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEE
FAPTRVTVGRMHELVLDYPTVLVDRAGPGSRYDSVVLDNAAAMAELVAHLQAQGYRRIGG
EECCHHHHHHHHHHHHHCCHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHH
LFGSTSTTAAERRDGYLAAMHAQGLAPDYREVAPTAEAAIAELEHWLAAADRPEAIVTSN
HCCCCCCHHHHHCCCEEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCEEEECC
SLLLMGALKAARTAGLRLPQDLALAGFDNERWTDLVEPGITVVEQPVEDMGRAAMSLLLE
CCHHHHHHHHHHHHCCCCCHHHEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RLASPQLPIRRMVMTGRCVVRGSTGARRPGI
HHCCCCCCHHHHHHCCCEEEECCCCCCCCCC
>Mature Secondary Structure 
SISINDVARVAGVSKSTVSRALGTGPVSEEVRAKVEAAVRQTGYRPNLMARRLRSQHSG
CCCHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
ILGVIVADIRNPYFTALIRAVEEVAYKAGMRVTLCNTDEDPEREALYLELMQEERITGLI
EEEEHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEE
FAPTRVTVGRMHELVLDYPTVLVDRAGPGSRYDSVVLDNAAAMAELVAHLQAQGYRRIGG
EECCHHHHHHHHHHHHHCCHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHH
LFGSTSTTAAERRDGYLAAMHAQGLAPDYREVAPTAEAAIAELEHWLAAADRPEAIVTSN
HCCCCCCHHHHHCCCEEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCEEEECC
SLLLMGALKAARTAGLRLPQDLALAGFDNERWTDLVEPGITVVEQPVEDMGRAAMSLLLE
CCHHHHHHHHHHHHCCCCCHHHEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RLASPQLPIRRMVMTGRCVVRGSTGARRPGI
HHCCCCCCHHHHHHCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]