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The map label for this gene is blc [H]

Identifier: 66768006

GI number: 66768006

Start: 2021758

End: 2022294

Strand: Reverse

Name: blc [H]

Synonym: XC_1682

Alternate gene names: 66768006

Gene position: 2022294-2021758 (Counterclockwise)

Preceding gene: 66768008

Following gene: 66768005

Centisome position: 39.28

GC content: 67.6

Gene sequence:

>537_bases
ATGCGCCTGCCTCGCCTGTTGTTGTCATTCGCCGCCCTGCTGCCGCTGGCTGCCCTTGCGCAGCAACCGGTGCGCGCCGT
GCCGGCGTTGGATATCTCGCGTTATGCCGGGCAGTGGCACGAGATCGCCCATCTACCGGTGTCGTTCCAGAAGAAATGCC
GCAGCGATATCACCGCCAGCTACACCTTGCGCGACGACGGCCTGATCGGGGTGCGCAATGGCTGCCGCGTTGCCGATGGC
AGCCTGACCCAGGCCGACGGCGTGGCACGCCCGGTGGCCGGGCACCCCGGGCAGTTGCAGGTGCGCTTCGCGCCGGAATG
GCTGTCGTGGATCCCGCTGGTCTGGGCGGACTACTGGGTGATTGCGCTCGATCCCGACTATCAGTGGGCGGTGGTCGGCG
AGCCGGATCGCAAGTACCTGTGGATCCTGTCGCGCTCGCCAGAGATGCCGCGCGCGCAGTTCGAGCAGTTGAAGGCCACC
GCCACGCAGATGGGCTACGACCTGTCGCCCCTGATTGTGGCGGCGCCACTGCGCTGA

Upstream 100 bases:

>100_bases
ATGTCGTGTTGGGGCTGAGCCGCAGCCCGGTTTCTTGCGCCGGTTCACGCCAAGCGGGGGCGCCGATGGCCTAGCCTGCG
CGCGTCCTTTGGAGATTCGC

Downstream 100 bases:

>100_bases
GGGCGGCCACCGCCCGGCGGGCACCGTACTGCGTAGTATTCTTGGCAATGCACCAACCCGCCAAGGAACCGAGTTCATGC
ACCGTGCCTTTCGCCTCCTG

Product: outer membrane lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MRLPRLLLSFAALLPLAALAQQPVRAVPALDISRYAGQWHEIAHLPVSFQKKCRSDITASYTLRDDGLIGVRNGCRVADG
SLTQADGVARPVAGHPGQLQVRFAPEWLSWIPLVWADYWVIALDPDYQWAVVGEPDRKYLWILSRSPEMPRAQFEQLKAT
ATQMGYDLSPLIVAAPLR

Sequences:

>Translated_178_residues
MRLPRLLLSFAALLPLAALAQQPVRAVPALDISRYAGQWHEIAHLPVSFQKKCRSDITASYTLRDDGLIGVRNGCRVADG
SLTQADGVARPVAGHPGQLQVRFAPEWLSWIPLVWADYWVIALDPDYQWAVVGEPDRKYLWILSRSPEMPRAQFEQLKAT
ATQMGYDLSPLIVAAPLR
>Mature_178_residues
MRLPRLLLSFAALLPLAALAQQPVRAVPALDISRYAGQWHEIAHLPVSFQKKCRSDITASYTLRDDGLIGVRNGCRVADG
SLTQADGVARPVAGHPGQLQVRFAPEWLSWIPLVWADYWVIALDPDYQWAVVGEPDRKYLWILSRSPEMPRAQFEQLKAT
ATQMGYDLSPLIVAAPLR

Specific function: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids [H]

COG id: COG3040

COG function: function code M; Bacterial lipocalin

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the calycin superfamily. Lipocalin family [H]

Homologues:

Organism=Homo sapiens, GI4502163, Length=154, Percent_Identity=31.8181818181818, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1790592, Length=174, Percent_Identity=36.2068965517241, Blast_Score=93, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012674
- InterPro:   IPR011038
- InterPro:   IPR013208
- InterPro:   IPR022271
- InterPro:   IPR002446
- InterPro:   IPR022272 [H]

Pfam domain/function: PF08212 Lipocalin_2 [H]

EC number: NA

Molecular weight: Translated: 19870; Mature: 19870

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS00142 ZINC_PROTEASE ; PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLPRLLLSFAALLPLAALAQQPVRAVPALDISRYAGQWHEIAHLPVSFQKKCRSDITAS
CCHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHCCCHHHHCCCCCHHHHHHHCCCEEE
YTLRDDGLIGVRNGCRVADGSLTQADGVARPVAGHPGQLQVRFAPEWLSWIPLVWADYWV
EEECCCCEEEECCCCEECCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCEEE
IALDPDYQWAVVGEPDRKYLWILSRSPEMPRAQFEQLKATATQMGYDLSPLIVAAPLR
EEECCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCC
>Mature Secondary Structure
MRLPRLLLSFAALLPLAALAQQPVRAVPALDISRYAGQWHEIAHLPVSFQKKCRSDITAS
CCHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHCCCHHHHCCCCCHHHHHHHCCCEEE
YTLRDDGLIGVRNGCRVADGSLTQADGVARPVAGHPGQLQVRFAPEWLSWIPLVWADYWV
EEECCCCEEEECCCCEECCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCEEE
IALDPDYQWAVVGEPDRKYLWILSRSPEMPRAQFEQLKATATQMGYDLSPLIVAAPLR
EEECCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]