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The map label for this gene is celR [H]

Identifier: 66767973

GI number: 66767973

Start: 1983882

End: 1985015

Strand: Reverse

Name: celR [H]

Synonym: XC_1649

Alternate gene names: 66767973

Gene position: 1985015-1983882 (Counterclockwise)

Preceding gene: 77761160

Following gene: 66767969

Centisome position: 38.55

GC content: 65.87

Gene sequence:

>1134_bases
TTGCCGATCATGACCATCAAGGGTAAAGCCACCTCGCTGGATATCGCCTACCTGGCCGGCGTCTCGCAACCGACCGTTTC
GCGTGCCCTGCGCGGCAGCCCGATGGTGAACGAGGACACCCGCCAGCGGATCCTGCGGATTGCCCGCGAGCTGAACTATA
AGGTCGACAAAAACGCCTCCTCGCTGCGGCTGCGCAACGCCGGCACGCTGGCGCTGCTGTTCTTCGAAGACCCCACCGCC
GATGACTCGCTGATCAACCCGTTCTTCCACTCGATGCTGGGCTCGATCACCCGTGCCTGCGCGCTGCAGGGCTACGACTT
GCTGGTGTCGTTCCAGCAGCTGTCCAAGGATTGGCAGGCCGATTACGAAGACAGCAACAAGGCCGACGGCATCATCCTGC
TCGGCTACGGCGATTATCAGGAATCACGCCAGCGGCTGCAGCTGCTGGTCGAACAAGGCACGCACTTCGTACGCTGGGGC
GCGGCGCTGCCGGGTCAACCGGGTATTTCGATCGGCAGCGATAACTATCAGGGCGGGCTGGACATCACCGAGCACCTGCT
CGCGCAGGGCTGCCGGCGGATCGCATTTCTCGGCCACGCCTCCAACCATTACCCGGAGTTCGAGGAGCGCTATCGCGGGC
ATGTCGCAGCGTTAGCGTTACAGGGTGTGGCGGCGGATGCCGCGCTGCAGTTCGATGCGATTACCACCGAGCTGTCCGGT
TACACCGCGTGCCTGGCGCTGCTCGACAGCGGGCAGGCGTTCGACGCGGTGTGCGCGGCCAGCGATTTGATTGCGATCGG
CGCGATGCGGGCACTGCGCGAACGCGGACTGCGCGTGCCGCAGGACGTGGCCGTCAGCGGCTTCGACGACATCGCCCTGG
CTGCCTCGGTGGCGCCAGCACTATCGACCGTGCAACAGGACACCAAGCAGGCCGGCGCCCTGTTGGTCGAAAGCCTGGTG
GCGCTGATTCGTGGTGACGCTGCACAGAGCCGCACAATCCCGGTTCGGCTGGCGGTGCGCGAGTCGTCGACCAGCAGTGG
CCTGCAACCGCCGCTGGGGTGGAACCCGTCGACGGCTGCGGAGTCCAGCGATGGGCTGCGCGGGAAGGCGGCGAGCGGAA
ACGCGACGCGCTGA

Upstream 100 bases:

>100_bases
AGGGTGTCTGAGGCGAATGGTAAACCAATCAGCGGGCCGATGCGCGTGGCAGCACGGGCCCGGCGGGCGCATGGCATGAT
GCCGGCCACTTGTCCTGCCG

Downstream 100 bases:

>100_bases
GATTCGGGAAGCGGGAAGCGGGAAGCGGGAAGCGGGAAGCGGGAAGCGGGAATCGTTGGAGCATGCGTCGCGCGGATGAG
TCGCCATCGTTGTTGGTCGC

Product: maltose transport gene repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MPIMTIKGKATSLDIAYLAGVSQPTVSRALRGSPMVNEDTRQRILRIARELNYKVDKNASSLRLRNAGTLALLFFEDPTA
DDSLINPFFHSMLGSITRACALQGYDLLVSFQQLSKDWQADYEDSNKADGIILLGYGDYQESRQRLQLLVEQGTHFVRWG
AALPGQPGISIGSDNYQGGLDITEHLLAQGCRRIAFLGHASNHYPEFEERYRGHVAALALQGVAADAALQFDAITTELSG
YTACLALLDSGQAFDAVCAASDLIAIGAMRALRERGLRVPQDVAVSGFDDIALAASVAPALSTVQQDTKQAGALLVESLV
ALIRGDAAQSRTIPVRLAVRESSTSSGLQPPLGWNPSTAAESSDGLRGKAASGNATR

Sequences:

>Translated_377_residues
MPIMTIKGKATSLDIAYLAGVSQPTVSRALRGSPMVNEDTRQRILRIARELNYKVDKNASSLRLRNAGTLALLFFEDPTA
DDSLINPFFHSMLGSITRACALQGYDLLVSFQQLSKDWQADYEDSNKADGIILLGYGDYQESRQRLQLLVEQGTHFVRWG
AALPGQPGISIGSDNYQGGLDITEHLLAQGCRRIAFLGHASNHYPEFEERYRGHVAALALQGVAADAALQFDAITTELSG
YTACLALLDSGQAFDAVCAASDLIAIGAMRALRERGLRVPQDVAVSGFDDIALAASVAPALSTVQQDTKQAGALLVESLV
ALIRGDAAQSRTIPVRLAVRESSTSSGLQPPLGWNPSTAAESSDGLRGKAASGNATR
>Mature_376_residues
PIMTIKGKATSLDIAYLAGVSQPTVSRALRGSPMVNEDTRQRILRIARELNYKVDKNASSLRLRNAGTLALLFFEDPTAD
DSLINPFFHSMLGSITRACALQGYDLLVSFQQLSKDWQADYEDSNKADGIILLGYGDYQESRQRLQLLVEQGTHFVRWGA
ALPGQPGISIGSDNYQGGLDITEHLLAQGCRRIAFLGHASNHYPEFEERYRGHVAALALQGVAADAALQFDAITTELSGY
TACLALLDSGQAFDAVCAASDLIAIGAMRALRERGLRVPQDVAVSGFDDIALAASVAPALSTVQQDTKQAGALLVESLVA
LIRGDAAQSRTIPVRLAVRESSTSSGLQPPLGWNPSTAAESSDGLRGKAASGNATR

Specific function: Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase genes; these operator sequences are modulated by cellobiose [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=319, Percent_Identity=29.4670846394984, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1789068, Length=337, Percent_Identity=29.3768545994065, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789202, Length=299, Percent_Identity=31.438127090301, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1790369, Length=342, Percent_Identity=28.3625730994152, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1790715, Length=335, Percent_Identity=24.7761194029851, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787948, Length=349, Percent_Identity=26.3610315186246, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1788474, Length=312, Percent_Identity=27.2435897435897, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1789456, Length=332, Percent_Identity=27.1084337349398, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI48994940, Length=334, Percent_Identity=23.0538922155689, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786540, Length=345, Percent_Identity=27.8260869565217, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787906, Length=381, Percent_Identity=24.6719160104987, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 40306; Mature: 40175

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIMTIKGKATSLDIAYLAGVSQPTVSRALRGSPMVNEDTRQRILRIARELNYKVDKNAS
CCEEEECCCCCEEEHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
SLRLRNAGTLALLFFEDPTADDSLINPFFHSMLGSITRACALQGYDLLVSFQQLSKDWQA
CEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
DYEDSNKADGIILLGYGDYQESRQRLQLLVEQGTHFVRWGAALPGQPGISIGSDNYQGGL
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCC
DITEHLLAQGCRRIAFLGHASNHYPEFEERYRGHVAALALQGVAADAALQFDAITTELSG
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHH
YTACLALLDSGQAFDAVCAASDLIAIGAMRALRERGLRVPQDVAVSGFDDIALAASVAPA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHH
LSTVQQDTKQAGALLVESLVALIRGDAAQSRTIPVRLAVRESSTSSGLQPPLGWNPSTAA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCC
ESSDGLRGKAASGNATR
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PIMTIKGKATSLDIAYLAGVSQPTVSRALRGSPMVNEDTRQRILRIARELNYKVDKNAS
CEEEECCCCCEEEHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
SLRLRNAGTLALLFFEDPTADDSLINPFFHSMLGSITRACALQGYDLLVSFQQLSKDWQA
CEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
DYEDSNKADGIILLGYGDYQESRQRLQLLVEQGTHFVRWGAALPGQPGISIGSDNYQGGL
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCC
DITEHLLAQGCRRIAFLGHASNHYPEFEERYRGHVAALALQGVAADAALQFDAITTELSG
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHH
YTACLALLDSGQAFDAVCAASDLIAIGAMRALRERGLRVPQDVAVSGFDDIALAASVAPA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHH
LSTVQQDTKQAGALLVESLVALIRGDAAQSRTIPVRLAVRESSTSSGLQPPLGWNPSTAA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCC
ESSDGLRGKAASGNATR
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10224066 [H]