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The map label for this gene is pepO [H]

Identifier: 66767866

GI number: 66767866

Start: 1850215

End: 1852227

Strand: Reverse

Name: pepO [H]

Synonym: XC_1542

Alternate gene names: 66767866

Gene position: 1852227-1850215 (Counterclockwise)

Preceding gene: 66767867

Following gene: 66767859

Centisome position: 35.97

GC content: 66.82

Gene sequence:

>2013_bases
ATGCCCACCATTCGTCCGCTTGCCCTCGCTCTTGGCTTCAGCCTGATCACGCTGTTGTCCGCCCCTGACGCCGACGCCGC
TCGCAAGAAGAAGGCAGCCCCCAAGGCCCCGGCTGTGCCGGCCGCCTGCACCGATTTCTACGATTACGCCAATGCCGGTT
GGCTCAAGAGCAACCCGGTGCCGCAGGCTGGCGCGGTCACCGCGCTGGGCCAGCTGTCCGACCGCGCCCTGCAGCAGCAG
CGCGAGCTGCTGGATGCGGCGATGAACAGCCCGCAAGGAAACGTGCAGAAGTTGCTCGGCGACTTCTGGGCCAGCGGCCT
GGATGAGGCCGCCGTGGAAAAGGACGGTTCCAATCCGATCGCCCCGTTGCTGTCGCGCATCGATGCGATCAAGAAGGCCA
AGGATGTGCCCGCTTCGATCGCCGCGCTGCACCAGGTCGGTATCCCGGTCGGCTTCAACTTCGGCCCGGACGTGGACCTG
AAGGCGCTCGACCGCCACATCGGTTACTTCATGCAGGGCGGCATGGGCATGCCGGATCCGGCGTTCTACACCCGCACCGA
CGCCGACACCCAGGCGCTGATGGGCCGCTACCGCGCCTACGTCAAGCAGATCCTGGCGCTGACCGGCACCCCGGCCGACA
AGCTCGATGCCGATGCGGCCTCGGTGTTACAGATCGAAACCGCACTGGCGCGCAGCGCGCAGTCCGTGCAGGGCATCAAC
AACCCGTTCAACAACTACGCGCCGATCGCCACCAAGGAGCTGACCAAGCAGTACAAGAACCTGCGCCTGGGCGACTTCCT
CGAGGCCCAGGGTGTCAAGGACGACCTGGTGTCGATGGCCGACCCGGCGATGTTCAAGCAGCTCGACAGCATGATCGTCA
GCATCAAGCCCGAGCAGTGGAAGGCCTACCTGCGCTGGCGCGTGGGCGATGCCATGGCGCCGTACCTGTCCAAGAGCTTC
CATGACGCCGAATACCAGTTCCGCGGCCGCTTGCTGCGTGGCGACGCCTTGCCGCCGCAGCGCTGGCAGCAGGTGCTCGA
TGCCATCAACGTGGCCGCCGGCCCGATGCTCGGCCGCGAGTACGTGAGCCGTTACCTCAGCAGCGACACCCGCCGCCAGG
CCGAAGCCATCGCCGACCAGATCCGCGATGCGCAGCTGGCCGCGCTGGAGCGCACCGGCTGGGGCAATGGCGAGGTCATC
GCCGAAGCCAAGGCCAAGCTGAGCGCCATGAAGATCGAAGTGGGCGCACCGCGCCGCGACCTCGACTACACCGTGCAGCC
GATGGGCCGTGGCAGCTTCGGCGCCAACATGCTGATCGCCTCCACCTGGCGTCACCGCGAAGAAATGAAGCGCATCGGCA
AGGGCAACGCCGACCGCCGTTGGGACGTGCTGCCGCAGCAGCCGGCGCTGGCCTACGACATCGCACAGAACCGCCTGATC
ATCACCGCTGCGGTGCTGCAGCCGCCGGTCTTGAGCACCGGCGCCACGCCGGCTGCACAATACGGTGCCTACGGCGCGCT
GGTGGCGCATGAAATGACGCGTGCCATCGATGCCAAGGGTGCGCTGGTCGATGCCAAGGGCGAACTGCGCAGCTGGTGGA
CGCCCGCCGAAAAGAGCAGCTGGACGCTGCTGACTGGCAAGGTAGCCAACCAGTACGGTGCCTACGCCTACCCGGGCGTG
CCCAATGCCAAGGTCAATGGCGCACAGACCGCCGAAGAAAACCTGGCCGATCTGGCCGGCGTGGAGTTGGCGTGGCAGGC
CTTCAGCAAGGCGCAGCCGGCGGCAACCCAGGCCGACAAGCAGGCCTTCTTCACCGCCTGGGCCGGCCTGTGGGCGCAGC
AGCTGTCACCGAACGAAGCGGTGCAGCGTGCCAGTGCTGACATCCGTGCACCTGGCCAGTGGCGCACCAACGGCCCGCTG
TCCAACCTGCCGGAGTTCGGTGCCACCTTCAGCTGCAAGCCGGGCCAGCCGATGCAGCGTGTGGATGCAGACCAGTTGAA
GATCTGGCGCTGA

Upstream 100 bases:

>100_bases
CAGCGAGCGCTCGCACGGACGAACGGCCGCTGCGGCCTGCCTGCGCGAGGCGCAGCCTTGCTAAACTCCGCCGACTTCAA
TCTGGCCACCCTTCGTCTCG

Downstream 100 bases:

>100_bases
GTTAGCGCCCTGCGTCATCGGCAGTAATAAAAAAGAGCGCGGAATCCGCGCTCTTTTTTGTCTGGATTTTGAACCGTCGC
GTTGCTCACCACCGCCAAGC

Product: metallopeptidase

Products: NA

Alternate protein names: Endopeptidase O [H]

Number of amino acids: Translated: 670; Mature: 669

Protein sequence:

>670_residues
MPTIRPLALALGFSLITLLSAPDADAARKKKAAPKAPAVPAACTDFYDYANAGWLKSNPVPQAGAVTALGQLSDRALQQQ
RELLDAAMNSPQGNVQKLLGDFWASGLDEAAVEKDGSNPIAPLLSRIDAIKKAKDVPASIAALHQVGIPVGFNFGPDVDL
KALDRHIGYFMQGGMGMPDPAFYTRTDADTQALMGRYRAYVKQILALTGTPADKLDADAASVLQIETALARSAQSVQGIN
NPFNNYAPIATKELTKQYKNLRLGDFLEAQGVKDDLVSMADPAMFKQLDSMIVSIKPEQWKAYLRWRVGDAMAPYLSKSF
HDAEYQFRGRLLRGDALPPQRWQQVLDAINVAAGPMLGREYVSRYLSSDTRRQAEAIADQIRDAQLAALERTGWGNGEVI
AEAKAKLSAMKIEVGAPRRDLDYTVQPMGRGSFGANMLIASTWRHREEMKRIGKGNADRRWDVLPQQPALAYDIAQNRLI
ITAAVLQPPVLSTGATPAAQYGAYGALVAHEMTRAIDAKGALVDAKGELRSWWTPAEKSSWTLLTGKVANQYGAYAYPGV
PNAKVNGAQTAEENLADLAGVELAWQAFSKAQPAATQADKQAFFTAWAGLWAQQLSPNEAVQRASADIRAPGQWRTNGPL
SNLPEFGATFSCKPGQPMQRVDADQLKIWR

Sequences:

>Translated_670_residues
MPTIRPLALALGFSLITLLSAPDADAARKKKAAPKAPAVPAACTDFYDYANAGWLKSNPVPQAGAVTALGQLSDRALQQQ
RELLDAAMNSPQGNVQKLLGDFWASGLDEAAVEKDGSNPIAPLLSRIDAIKKAKDVPASIAALHQVGIPVGFNFGPDVDL
KALDRHIGYFMQGGMGMPDPAFYTRTDADTQALMGRYRAYVKQILALTGTPADKLDADAASVLQIETALARSAQSVQGIN
NPFNNYAPIATKELTKQYKNLRLGDFLEAQGVKDDLVSMADPAMFKQLDSMIVSIKPEQWKAYLRWRVGDAMAPYLSKSF
HDAEYQFRGRLLRGDALPPQRWQQVLDAINVAAGPMLGREYVSRYLSSDTRRQAEAIADQIRDAQLAALERTGWGNGEVI
AEAKAKLSAMKIEVGAPRRDLDYTVQPMGRGSFGANMLIASTWRHREEMKRIGKGNADRRWDVLPQQPALAYDIAQNRLI
ITAAVLQPPVLSTGATPAAQYGAYGALVAHEMTRAIDAKGALVDAKGELRSWWTPAEKSSWTLLTGKVANQYGAYAYPGV
PNAKVNGAQTAEENLADLAGVELAWQAFSKAQPAATQADKQAFFTAWAGLWAQQLSPNEAVQRASADIRAPGQWRTNGPL
SNLPEFGATFSCKPGQPMQRVDADQLKIWR
>Mature_669_residues
PTIRPLALALGFSLITLLSAPDADAARKKKAAPKAPAVPAACTDFYDYANAGWLKSNPVPQAGAVTALGQLSDRALQQQR
ELLDAAMNSPQGNVQKLLGDFWASGLDEAAVEKDGSNPIAPLLSRIDAIKKAKDVPASIAALHQVGIPVGFNFGPDVDLK
ALDRHIGYFMQGGMGMPDPAFYTRTDADTQALMGRYRAYVKQILALTGTPADKLDADAASVLQIETALARSAQSVQGINN
PFNNYAPIATKELTKQYKNLRLGDFLEAQGVKDDLVSMADPAMFKQLDSMIVSIKPEQWKAYLRWRVGDAMAPYLSKSFH
DAEYQFRGRLLRGDALPPQRWQQVLDAINVAAGPMLGREYVSRYLSSDTRRQAEAIADQIRDAQLAALERTGWGNGEVIA
EAKAKLSAMKIEVGAPRRDLDYTVQPMGRGSFGANMLIASTWRHREEMKRIGKGNADRRWDVLPQQPALAYDIAQNRLII
TAAVLQPPVLSTGATPAAQYGAYGALVAHEMTRAIDAKGALVDAKGELRSWWTPAEKSSWTLLTGKVANQYGAYAYPGVP
NAKVNGAQTAEENLADLAGVELAWQAFSKAQPAATQADKQAFFTAWAGLWAQQLSPNEAVQRASADIRAPGQWRTNGPLS
NLPEFGATFSCKPGQPMQRVDADQLKIWR

Specific function: Unknown

COG id: COG3590

COG function: function code O; Predicted metalloendopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M13 family [H]

Homologues:

Organism=Homo sapiens, GI157426891, Length=669, Percent_Identity=25.4110612855007, Blast_Score=202, Evalue=1e-51,
Organism=Homo sapiens, GI239049391, Length=732, Percent_Identity=22.2677595628415, Blast_Score=193, Evalue=6e-49,
Organism=Homo sapiens, GI164519136, Length=655, Percent_Identity=23.5114503816794, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI164519138, Length=655, Percent_Identity=23.5114503816794, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI4503443, Length=655, Percent_Identity=23.5114503816794, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI164519140, Length=655, Percent_Identity=23.5114503816794, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI153945761, Length=647, Percent_Identity=23.4930448222566, Blast_Score=176, Evalue=9e-44,
Organism=Homo sapiens, GI153945771, Length=647, Percent_Identity=23.4930448222566, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI153945836, Length=647, Percent_Identity=23.4930448222566, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI82617560, Length=647, Percent_Identity=23.4930448222566, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI116256333, Length=674, Percent_Identity=22.106824925816, Blast_Score=173, Evalue=5e-43,
Organism=Homo sapiens, GI116256331, Length=674, Percent_Identity=22.106824925816, Blast_Score=173, Evalue=5e-43,
Organism=Homo sapiens, GI116256329, Length=674, Percent_Identity=22.106824925816, Blast_Score=173, Evalue=5e-43,
Organism=Homo sapiens, GI116256327, Length=674, Percent_Identity=22.106824925816, Blast_Score=173, Evalue=5e-43,
Organism=Homo sapiens, GI90403592, Length=688, Percent_Identity=22.9651162790698, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI4557691, Length=662, Percent_Identity=20.2416918429003, Blast_Score=110, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17533333, Length=681, Percent_Identity=22.4669603524229, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI25148650, Length=672, Percent_Identity=22.9166666666667, Blast_Score=159, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI71987442, Length=665, Percent_Identity=22.8571428571429, Blast_Score=149, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI86562497, Length=675, Percent_Identity=22.0740740740741, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI32563993, Length=633, Percent_Identity=22.1169036334913, Blast_Score=138, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17564342, Length=378, Percent_Identity=24.3386243386243, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17532485, Length=318, Percent_Identity=24.8427672955975, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17533319, Length=320, Percent_Identity=23.75, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71994787, Length=420, Percent_Identity=20.4761904761905, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17534401, Length=342, Percent_Identity=21.6374269005848, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17534885, Length=199, Percent_Identity=25.6281407035176, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71988640, Length=325, Percent_Identity=22.4615384615385, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI133931212, Length=321, Percent_Identity=21.4953271028037, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17570047, Length=247, Percent_Identity=26.7206477732794, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24643425, Length=667, Percent_Identity=23.3883058470765, Blast_Score=211, Evalue=1e-54,
Organism=Drosophila melanogaster, GI17737761, Length=675, Percent_Identity=21.6296296296296, Blast_Score=169, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24640050, Length=663, Percent_Identity=22.3227752639517, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24640052, Length=663, Percent_Identity=22.3227752639517, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI45550777, Length=547, Percent_Identity=24.6800731261426, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI45551938, Length=547, Percent_Identity=24.6800731261426, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI221474862, Length=317, Percent_Identity=24.2902208201893, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24650765, Length=393, Percent_Identity=21.6284987277354, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24650889, Length=210, Percent_Identity=30.4761904761905, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24650487, Length=220, Percent_Identity=29.0909090909091, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281362760, Length=206, Percent_Identity=31.0679611650485, Blast_Score=100, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24650885, Length=726, Percent_Identity=22.4517906336088, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21355943, Length=343, Percent_Identity=21.865889212828, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24650883, Length=199, Percent_Identity=24.1206030150754, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000718
- InterPro:   IPR018497
- InterPro:   IPR008753 [H]

Pfam domain/function: PF01431 Peptidase_M13; PF05649 Peptidase_M13_N [H]

EC number: NA

Molecular weight: Translated: 72730; Mature: 72599

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTIRPLALALGFSLITLLSAPDADAARKKKAAPKAPAVPAACTDFYDYANAGWLKSNPV
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
PQAGAVTALGQLSDRALQQQRELLDAAMNSPQGNVQKLLGDFWASGLDEAAVEKDGSNPI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCH
APLLSRIDAIKKAKDVPASIAALHQVGIPVGFNFGPDVDLKALDRHIGYFMQGGMGMPDP
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
AFYTRTDADTQALMGRYRAYVKQILALTGTPADKLDADAASVLQIETALARSAQSVQGIN
CCEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
NPFNNYAPIATKELTKQYKNLRLGDFLEAQGVKDDLVSMADPAMFKQLDSMIVSIKPEQW
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHCCHHHHHHHHHHHEECCHHHH
KAYLRWRVGDAMAPYLSKSFHDAEYQFRGRLLRGDALPPQRWQQVLDAINVAAGPMLGRE
HHHHHHHHCCHHHHHHHHHHCCCHHHHHCEEEECCCCCHHHHHHHHHHHHHHHCCHHHHH
YVSRYLSSDTRRQAEAIADQIRDAQLAALERTGWGNGEVIAEAKAKLSAMKIEVGAPRRD
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHEEEEECCCCCC
LDYTVQPMGRGSFGANMLIASTWRHREEMKRIGKGNADRRWDVLPQQPALAYDIAQNRLI
CCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCEE
ITAAVLQPPVLSTGATPAAQYGAYGALVAHEMTRAIDAKGALVDAKGELRSWWTPAEKSS
EEEHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCEECCCCCHHHCCCCCCCCC
WTLLTGKVANQYGAYAYPGVPNAKVNGAQTAEENLADLAGVELAWQAFSKAQPAATQADK
EEEEECHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QAFFTAWAGLWAQQLSPNEAVQRASADIRAPGQWRTNGPLSNLPEFGATFSCKPGQPMQR
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCEECCCCCCCHHH
VDADQLKIWR
CCHHHHEECC
>Mature Secondary Structure 
PTIRPLALALGFSLITLLSAPDADAARKKKAAPKAPAVPAACTDFYDYANAGWLKSNPV
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
PQAGAVTALGQLSDRALQQQRELLDAAMNSPQGNVQKLLGDFWASGLDEAAVEKDGSNPI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCH
APLLSRIDAIKKAKDVPASIAALHQVGIPVGFNFGPDVDLKALDRHIGYFMQGGMGMPDP
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
AFYTRTDADTQALMGRYRAYVKQILALTGTPADKLDADAASVLQIETALARSAQSVQGIN
CCEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
NPFNNYAPIATKELTKQYKNLRLGDFLEAQGVKDDLVSMADPAMFKQLDSMIVSIKPEQW
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHCCHHHHHHHHHHHEECCHHHH
KAYLRWRVGDAMAPYLSKSFHDAEYQFRGRLLRGDALPPQRWQQVLDAINVAAGPMLGRE
HHHHHHHHCCHHHHHHHHHHCCCHHHHHCEEEECCCCCHHHHHHHHHHHHHHHCCHHHHH
YVSRYLSSDTRRQAEAIADQIRDAQLAALERTGWGNGEVIAEAKAKLSAMKIEVGAPRRD
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHEEEEECCCCCC
LDYTVQPMGRGSFGANMLIASTWRHREEMKRIGKGNADRRWDVLPQQPALAYDIAQNRLI
CCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCEE
ITAAVLQPPVLSTGATPAAQYGAYGALVAHEMTRAIDAKGALVDAKGELRSWWTPAEKSS
EEEHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCEECCCCCHHHCCCCCCCCC
WTLLTGKVANQYGAYAYPGVPNAKVNGAQTAEENLADLAGVELAWQAFSKAQPAATQADK
EEEEECHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QAFFTAWAGLWAQQLSPNEAVQRASADIRAPGQWRTNGPLSNLPEFGATFSCKPGQPMQR
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCEECCCCCCCHHH
VDADQLKIWR
CCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9726890 [H]