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The map label for this gene is yccK [H]

Identifier: 66767762

GI number: 66767762

Start: 1734031

End: 1735014

Strand: Direct

Name: yccK [H]

Synonym: XC_1436

Alternate gene names: 66767762

Gene position: 1734031-1735014 (Clockwise)

Preceding gene: 66767761

Following gene: 66767764

Centisome position: 33.68

GC content: 66.06

Gene sequence:

>984_bases
ATGCATACACGCACACTAGGGCGCAGCGGGCTGCGGGTCTCCGCACTTGGCCTGGGCTGCATGGGGTTGAGCTACGGCTA
CGGGCCGGCCACCGAGCGCAAACAGGCGGTGGCACTGCTGCACGCCGCGGTGGAGCAGGGCGTGACCTTGTTCGACACCG
CAGAGGCGTACGGGCCGATCGCCAATGAGGAATTGCTGGGTGAGGCGCTTGCGCCGTACGGCGCGCAGGTGGTGGTTGCC
ACCAAGTTCGGCTTTCGCGATGGACATGCCGATGCCGGTCTGGACAGCCGGCCCGCGCGTATCCGCGCAGTGGCCGAGGC
CAGCCTGCTGCGGTTGAAGCGCGAGCGTATCGATCTGTTCTATCAGCACCGCGTGGATCCCGCGGTGCCGATCGAGGAAG
TGGCCGGCACGGTCAAGGATTTGATCGCCGAAGGCAAGGTGGGCCATTTCGGCCTGTCCGAAGCCAGCGCGGACACCATC
CGCCGCGCGCATGCGGTGCAACCGGTGGCCGCGGTGCAAAGCGAATACTCGCTGTGGTGGCGCGAACCGGAAGCCAGCGT
GCTGCCCACGCTGGAAGAACTGGGGATTGGCTTCGTGCCGTTCAGTCCGCTCGGCAAGGCATTTCTGACAGGCGCGATCC
AGCCCGACACGCAATTCGACCAGAGCGACTTCCGTAACAGCGTGCCGCGCTTTGCCGCGGAGGCGCGCCGTGCCAATCAG
GCGCTGGTGCAACGCCTGCAAGCCATCGCGGACGACAAGGGCGCGACGCCGGCACAGGTGGCGCTGGCCTGGCTATTGTC
GCGCAAGCCCTGGATCGTGCCGATTCCTGGCACCACCAAGCGTCATCGCCTGGACGAAAACATCGGCGGTGCTGCGCTCG
TCTTGAGCAGCGACGAGCTGGCACGTATTCAACAGGCACTCGATGCGGTGGAGATTGTCGGTGAGCGCTACAGCCCGGAG
CGGCAGAAGCTGGTGGGGAAGTGA

Upstream 100 bases:

>100_bases
ACTGCAATCCACCCGGCCTTGGCGGCTAACGTGTGCGCTCGGCGCTGCCACCTCACGTGGGACGCCATCGATCGACGCGG
CGCTGCCGCAGGAGCACACG

Downstream 100 bases:

>100_bases
GCACGGCGGTGTAACCGCAGTGACGGTATCTGCAAGAGATGTGTCGTAGGAGCGCGCGCGATGGGGCGTTACCGATAACG
CTTCATCGCGCGCGCTCCTA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MHTRTLGRSGLRVSALGLGCMGLSYGYGPATERKQAVALLHAAVEQGVTLFDTAEAYGPIANEELLGEALAPYGAQVVVA
TKFGFRDGHADAGLDSRPARIRAVAEASLLRLKRERIDLFYQHRVDPAVPIEEVAGTVKDLIAEGKVGHFGLSEASADTI
RRAHAVQPVAAVQSEYSLWWREPEASVLPTLEELGIGFVPFSPLGKAFLTGAIQPDTQFDQSDFRNSVPRFAAEARRANQ
ALVQRLQAIADDKGATPAQVALAWLLSRKPWIVPIPGTTKRHRLDENIGGAALVLSSDELARIQQALDAVEIVGERYSPE
RQKLVGK

Sequences:

>Translated_327_residues
MHTRTLGRSGLRVSALGLGCMGLSYGYGPATERKQAVALLHAAVEQGVTLFDTAEAYGPIANEELLGEALAPYGAQVVVA
TKFGFRDGHADAGLDSRPARIRAVAEASLLRLKRERIDLFYQHRVDPAVPIEEVAGTVKDLIAEGKVGHFGLSEASADTI
RRAHAVQPVAAVQSEYSLWWREPEASVLPTLEELGIGFVPFSPLGKAFLTGAIQPDTQFDQSDFRNSVPRFAAEARRANQ
ALVQRLQAIADDKGATPAQVALAWLLSRKPWIVPIPGTTKRHRLDENIGGAALVLSSDELARIQQALDAVEIVGERYSPE
RQKLVGK
>Mature_327_residues
MHTRTLGRSGLRVSALGLGCMGLSYGYGPATERKQAVALLHAAVEQGVTLFDTAEAYGPIANEELLGEALAPYGAQVVVA
TKFGFRDGHADAGLDSRPARIRAVAEASLLRLKRERIDLFYQHRVDPAVPIEEVAGTVKDLIAEGKVGHFGLSEASADTI
RRAHAVQPVAAVQSEYSLWWREPEASVLPTLEELGIGFVPFSPLGKAFLTGAIQPDTQFDQSDFRNSVPRFAAEARRANQ
ALVQRLQAIADDKGATPAQVALAWLLSRKPWIVPIPGTTKRHRLDENIGGAALVLSSDELARIQQALDAVEIVGERYSPE
RQKLVGK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=325, Percent_Identity=32.6153846153846, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI4504825, Length=322, Percent_Identity=33.2298136645963, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI27436964, Length=305, Percent_Identity=31.8032786885246, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI27436966, Length=305, Percent_Identity=31.8032786885246, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI27436962, Length=305, Percent_Identity=31.8032786885246, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI27436971, Length=305, Percent_Identity=32.1311475409836, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI223718702, Length=299, Percent_Identity=27.0903010033445, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI41327764, Length=290, Percent_Identity=27.5862068965517, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI41152114, Length=238, Percent_Identity=27.3109243697479, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87081735, Length=326, Percent_Identity=31.5950920245399, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1789375, Length=326, Percent_Identity=30.9815950920245, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787674, Length=312, Percent_Identity=31.0897435897436, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788070, Length=329, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789199, Length=345, Percent_Identity=27.8260869565217, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788081, Length=283, Percent_Identity=27.208480565371, Blast_Score=79, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6325169, Length=355, Percent_Identity=27.0422535211268, Blast_Score=113, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6325384, Length=340, Percent_Identity=27.0588235294118, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323998, Length=322, Percent_Identity=24.5341614906832, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319958, Length=297, Percent_Identity=22.2222222222222, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319951, Length=315, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6322615, Length=246, Percent_Identity=21.5447154471545, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24640980, Length=342, Percent_Identity=28.3625730994152, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI45549126, Length=339, Percent_Identity=28.6135693215339, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24646159, Length=168, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646155, Length=158, Percent_Identity=31.6455696202532, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35343; Mature: 35343

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTRTLGRSGLRVSALGLGCMGLSYGYGPATERKQAVALLHAAVEQGVTLFDTAEAYGPI
CCCCCCCCCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEECHHHHCCC
ANEELLGEALAPYGAQVVVATKFGFRDGHADAGLDSRPARIRAVAEASLLRLKRERIDLF
CCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YQHRVDPAVPIEEVAGTVKDLIAEGKVGHFGLSEASADTIRRAHAVQPVAAVQSEYSLWW
HHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHEE
REPEASVLPTLEELGIGFVPFSPLGKAFLTGAIQPDTQFDQSDFRNSVPRFAAEARRANQ
CCCCCCCCCCHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ALVQRLQAIADDKGATPAQVALAWLLSRKPWIVPIPGTTKRHRLDENIGGAALVLSSDEL
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHCCCCCEEEEECCHHH
ARIQQALDAVEIVGERYSPERQKLVGK
HHHHHHHHHHHHHHCCCCCHHHHHCCC
>Mature Secondary Structure
MHTRTLGRSGLRVSALGLGCMGLSYGYGPATERKQAVALLHAAVEQGVTLFDTAEAYGPI
CCCCCCCCCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEECHHHHCCC
ANEELLGEALAPYGAQVVVATKFGFRDGHADAGLDSRPARIRAVAEASLLRLKRERIDLF
CCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YQHRVDPAVPIEEVAGTVKDLIAEGKVGHFGLSEASADTIRRAHAVQPVAAVQSEYSLWW
HHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHEE
REPEASVLPTLEELGIGFVPFSPLGKAFLTGAIQPDTQFDQSDFRNSVPRFAAEARRANQ
CCCCCCCCCCHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ALVQRLQAIADDKGATPAQVALAWLLSRKPWIVPIPGTTKRHRLDENIGGAALVLSSDEL
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHCCCCCEEEEECCHHH
ARIQQALDAVEIVGERYSPERQKLVGK
HHHHHHHHHHHHHHCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]