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The map label for this gene is gpmA [H]

Identifier: 66767730

GI number: 66767730

Start: 1692995

End: 1693744

Strand: Direct

Name: gpmA [H]

Synonym: XC_1404

Alternate gene names: 66767730

Gene position: 1692995-1693744 (Clockwise)

Preceding gene: 66767726

Following gene: 66767731

Centisome position: 32.88

GC content: 66.0

Gene sequence:

>750_bases
GTGACCCGCAAACTCGTACTGCTGCGCCATGGCCAGAGCCAATGGAACCTGGACAACCGTTTCACCGGCTGGGTGGACGT
GGATCTCACCGAGCAGGGCCGCCAGGAAGCCGCCGCGGCCGGCAAGCTGATGAAGGACGAAGGGCTGCAGTTCGATGTGG
CGTACACCTCGGTGCTCAAGCGCGCCATCCACACGCTGCAGGGCGCGCTGAAGGAGCTCGACCAGGACTGGCTGCCGGTG
CACAAGAGCTGGCGCCTCAATGAGCGTCACTACGGTGGCCTGCAGGGCCTGGACAAGGCCGAAACCGCGGCCAAGCACGG
CGAAGAGCAGGTCAAGATCTGGCGCCGTTCCTACGACATCCCGCCGCCGGCCATGGACGTCACCGATCCGGGCCATCCCG
GGCATGACCGCCGCTATGCCACGCTGGACCGCAATGCATTGCCGGGCACCGAGTCGCTGGCGACCACGCTGGTGCGCGTG
TTGCCGTACTGGCACGACGCGATCGCCCCGCAGTTGAAGGCCGGCCAGACCGTGCTGGTCACCGCGCACGGCAACTCGTT
GCGCGCGCTGTACAAGTACCTCAACGACATCTCCAACGCGCAGATCCTGGAGCTCAACATTCCCACCGGCATCCCGCTGT
TGTTCGAGCTGGACGACAACCTGCAGGTGCAAAGCTACCGCTACCTGGGCGACCCGGAAGCGGCCAAGCGCGCCGCCGAA
GCCGTGGCCAACCAGGGCAAGGCCAAGTAA

Upstream 100 bases:

>100_bases
CGCAGCATCGCGCGCACGCCGTGGCGATGCCGTGCACGCCAGGCAGGCATCGGCTGCCGCTACAATCAGCGGTTGATCGG
CCCCCAATCGGAGAACCGTA

Downstream 100 bases:

>100_bases
GCCGCGCAGCGGGCGTGCACGCAGCACGCCCGCTGCCGGATTGGCCGGTGCTGCCGCCATGCATGAGGCGTGGCGGCGTT
GGCCGTGATGCAGCGGCGTG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTRKLVLLRHGQSQWNLDNRFTGWVDVDLTEQGRQEAAAAGKLMKDEGLQFDVAYTSVLKRAIHTLQGALKELDQDWLPV
HKSWRLNERHYGGLQGLDKAETAAKHGEEQVKIWRRSYDIPPPAMDVTDPGHPGHDRRYATLDRNALPGTESLATTLVRV
LPYWHDAIAPQLKAGQTVLVTAHGNSLRALYKYLNDISNAQILELNIPTGIPLLFELDDNLQVQSYRYLGDPEAAKRAAE
AVANQGKAK

Sequences:

>Translated_249_residues
MTRKLVLLRHGQSQWNLDNRFTGWVDVDLTEQGRQEAAAAGKLMKDEGLQFDVAYTSVLKRAIHTLQGALKELDQDWLPV
HKSWRLNERHYGGLQGLDKAETAAKHGEEQVKIWRRSYDIPPPAMDVTDPGHPGHDRRYATLDRNALPGTESLATTLVRV
LPYWHDAIAPQLKAGQTVLVTAHGNSLRALYKYLNDISNAQILELNIPTGIPLLFELDDNLQVQSYRYLGDPEAAKRAAE
AVANQGKAK
>Mature_248_residues
TRKLVLLRHGQSQWNLDNRFTGWVDVDLTEQGRQEAAAAGKLMKDEGLQFDVAYTSVLKRAIHTLQGALKELDQDWLPVH
KSWRLNERHYGGLQGLDKAETAAKHGEEQVKIWRRSYDIPPPAMDVTDPGHPGHDRRYATLDRNALPGTESLATTLVRVL
PYWHDAIAPQLKAGQTVLVTAHGNSLRALYKYLNDISNAQILELNIPTGIPLLFELDDNLQVQSYRYLGDPEAAKRAAEA
VANQGKAK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=251, Percent_Identity=56.5737051792829, Blast_Score=300, Evalue=9e-82,
Organism=Homo sapiens, GI4505753, Length=249, Percent_Identity=57.0281124497992, Blast_Score=287, Evalue=7e-78,
Organism=Homo sapiens, GI71274132, Length=249, Percent_Identity=55.0200803212851, Blast_Score=272, Evalue=2e-73,
Organism=Homo sapiens, GI4502445, Length=251, Percent_Identity=49.003984063745, Blast_Score=257, Evalue=8e-69,
Organism=Homo sapiens, GI40353764, Length=251, Percent_Identity=49.003984063745, Blast_Score=257, Evalue=8e-69,
Organism=Homo sapiens, GI310129614, Length=161, Percent_Identity=59.6273291925466, Blast_Score=189, Evalue=2e-48,
Organism=Escherichia coli, GI1786970, Length=246, Percent_Identity=62.6016260162602, Blast_Score=319, Evalue=1e-88,
Organism=Saccharomyces cerevisiae, GI6322697, Length=244, Percent_Identity=58.6065573770492, Blast_Score=279, Evalue=3e-76,
Organism=Saccharomyces cerevisiae, GI6324516, Length=301, Percent_Identity=33.2225913621262, Blast_Score=147, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6320183, Length=299, Percent_Identity=32.4414715719064, Blast_Score=140, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24646216, Length=250, Percent_Identity=54, Blast_Score=281, Evalue=2e-76,
Organism=Drosophila melanogaster, GI85725270, Length=250, Percent_Identity=54.8, Blast_Score=264, Evalue=5e-71,
Organism=Drosophila melanogaster, GI85725272, Length=250, Percent_Identity=54.8, Blast_Score=264, Evalue=5e-71,
Organism=Drosophila melanogaster, GI24650981, Length=250, Percent_Identity=54.8, Blast_Score=264, Evalue=5e-71,
Organism=Drosophila melanogaster, GI28571817, Length=255, Percent_Identity=39.2156862745098, Blast_Score=169, Evalue=1e-42,
Organism=Drosophila melanogaster, GI28571815, Length=255, Percent_Identity=39.2156862745098, Blast_Score=169, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24648979, Length=255, Percent_Identity=39.2156862745098, Blast_Score=169, Evalue=1e-42,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 27918; Mature: 27787

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKLVLLRHGQSQWNLDNRFTGWVDVDLTEQGRQEAAAAGKLMKDEGLQFDVAYTSVLK
CCCEEEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHH
RAIHTLQGALKELDQDWLPVHKSWRLNERHYGGLQGLDKAETAAKHGEEQVKIWRRSYDI
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCC
PPPAMDVTDPGHPGHDRRYATLDRNALPGTESLATTLVRVLPYWHDAIAPQLKAGQTVLV
CCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCEEEE
TAHGNSLRALYKYLNDISNAQILELNIPTGIPLLFELDDNLQVQSYRYLGDPEAAKRAAE
EECCCHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCEEEEEEECCCHHHHHHHHH
AVANQGKAK
HHHHCCCCC
>Mature Secondary Structure 
TRKLVLLRHGQSQWNLDNRFTGWVDVDLTEQGRQEAAAAGKLMKDEGLQFDVAYTSVLK
CCEEEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHH
RAIHTLQGALKELDQDWLPVHKSWRLNERHYGGLQGLDKAETAAKHGEEQVKIWRRSYDI
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCC
PPPAMDVTDPGHPGHDRRYATLDRNALPGTESLATTLVRVLPYWHDAIAPQLKAGQTVLV
CCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCEEEE
TAHGNSLRALYKYLNDISNAQILELNIPTGIPLLFELDDNLQVQSYRYLGDPEAAKRAAE
EECCCHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCEEEEEEECCCHHHHHHHHH
AVANQGKAK
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]