Click here to switch to the map view.

The map label for this gene is yieH [H]

Identifier: 66767722

GI number: 66767722

Start: 1684712

End: 1685389

Strand: Direct

Name: yieH [H]

Synonym: XC_1396

Alternate gene names: 66767722

Gene position: 1684712-1685389 (Clockwise)

Preceding gene: 66767719

Following gene: 66767725

Centisome position: 32.72

GC content: 66.67

Gene sequence:

>678_bases
ATGGCGTACGAGCTACTGATCAGTGACTGCGATGGGGTTCTTGTCGACAGCGAAATCCTGGCCGACCGGGTAATGCGTGA
GGCGCTGGCAGCGTTCGTGCCGGCCGAGCCGTTGGAACATCTGCTGGAAACCACGTTCGGGCAGACCACGCGCGAGGTAT
TGCGGCGGGTGGAAGAACACTTTGCGCTGCAGTTGCCGGAAACCTTGCTGGCGCAGATCCAGGCGCGCAGCGAAGCCTTG
ATCGCCGCCGAGGTGCAGCCGATTGCGGGCGTGCGACAGGCGCTGGAGCAGATCCCGCTGCCGCTGGCGGTGGCCTCCAA
TAGCCGCCGCCACAACGTGATTGCATCGGTGGAGCGGGCCGGGCTCACGGCGCGTGCGGCAGGGCGGATCTTCAGCGCCG
ACATGGTGGAGCGGCCCAAGCCCGCACCGGATGTTTACCTGCTGGCCGCGCGCACGGCCGGTGTAGCACCGGAGCGTTGC
CTGGTCATCGAAGACAGCCCCACCGGTGCGACCGCCGCGCTGGCGGCCGGCATGCAGGTGCTGGGCTTTACCGGTGCCAG
CCATATTCCGCAAGGGCACGGCGACACCCTGCGACGGATCGGCGTGCTGGAGGTGTTCGACGATATGCGCGATTTGCACG
CATTGTTCGAGCGGCTCGCGCAAACGCGCGCTGGTTGA

Upstream 100 bases:

>100_bases
ACGGGCGCGCGGGCGTCTTCGTCCCCTGTGCGGGCGCTGCGCCACAGCCGACGGTCACGACCGGGTCGGCATAATGGCGC
TTTGCAAGCAGATGGGTGCA

Downstream 100 bases:

>100_bases
GGGTGTCGCGTCGTTGCTTCGTTTGGCTGCAGTCAGTGCTTGGATCAAAAGTCTGGTCGGTCGCGCGTGCGGTGCCCTCA
CCGCTTGCGGACACGCCGCA

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MAYELLISDCDGVLVDSEILADRVMREALAAFVPAEPLEHLLETTFGQTTREVLRRVEEHFALQLPETLLAQIQARSEAL
IAAEVQPIAGVRQALEQIPLPLAVASNSRRHNVIASVERAGLTARAAGRIFSADMVERPKPAPDVYLLAARTAGVAPERC
LVIEDSPTGATAALAAGMQVLGFTGASHIPQGHGDTLRRIGVLEVFDDMRDLHALFERLAQTRAG

Sequences:

>Translated_225_residues
MAYELLISDCDGVLVDSEILADRVMREALAAFVPAEPLEHLLETTFGQTTREVLRRVEEHFALQLPETLLAQIQARSEAL
IAAEVQPIAGVRQALEQIPLPLAVASNSRRHNVIASVERAGLTARAAGRIFSADMVERPKPAPDVYLLAARTAGVAPERC
LVIEDSPTGATAALAAGMQVLGFTGASHIPQGHGDTLRRIGVLEVFDDMRDLHALFERLAQTRAG
>Mature_224_residues
AYELLISDCDGVLVDSEILADRVMREALAAFVPAEPLEHLLETTFGQTTREVLRRVEEHFALQLPETLLAQIQARSEALI
AAEVQPIAGVRQALEQIPLPLAVASNSRRHNVIASVERAGLTARAAGRIFSADMVERPKPAPDVYLLAARTAGVAPERCL
VIEDSPTGATAALAAGMQVLGFTGASHIPQGHGDTLRRIGVLEVFDDMRDLHALFERLAQTRAG

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates phosphoenolpyruvate and AMP [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1790151, Length=187, Percent_Identity=27.807486631016, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789046, Length=179, Percent_Identity=31.8435754189944, Blast_Score=63, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17137324, Length=183, Percent_Identity=31.1475409836066, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 24258; Mature: 24127

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYELLISDCDGVLVDSEILADRVMREALAAFVPAEPLEHLLETTFGQTTREVLRRVEEH
CCCEEEEECCCCEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHH
FALQLPETLLAQIQARSEALIAAEVQPIAGVRQALEQIPLPLAVASNSRRHNVIASVERA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHH
GLTARAAGRIFSADMVERPKPAPDVYLLAARTAGVAPERCLVIEDSPTGATAALAAGMQV
CCHHHHHCCHHHHHHHCCCCCCCCEEEEEEHHCCCCCCEEEEEECCCCCHHHHHHHHHHH
LGFTGASHIPQGHGDTLRRIGVLEVFDDMRDLHALFERLAQTRAG
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AYELLISDCDGVLVDSEILADRVMREALAAFVPAEPLEHLLETTFGQTTREVLRRVEEH
CCEEEEECCCCEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHH
FALQLPETLLAQIQARSEALIAAEVQPIAGVRQALEQIPLPLAVASNSRRHNVIASVERA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHH
GLTARAAGRIFSADMVERPKPAPDVYLLAARTAGVAPERCLVIEDSPTGATAALAAGMQV
CCHHHHHCCHHHHHHHCCCCCCCCEEEEEEHHCCCCCCEEEEEECCCCCHHHHHHHHHHH
LGFTGASHIPQGHGDTLRRIGVLEVFDDMRDLHALFERLAQTRAG
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]