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The map label for this gene is sufC [H]

Identifier: 66767673

GI number: 66767673

Start: 1632837

End: 1633601

Strand: Reverse

Name: sufC [H]

Synonym: XC_1346

Alternate gene names: 66767673

Gene position: 1633601-1632837 (Counterclockwise)

Preceding gene: 66767674

Following gene: 66767672

Centisome position: 31.73

GC content: 63.4

Gene sequence:

>765_bases
ATGCTCAACATTCAAAATCTCCACGCCAGCATCGCCGGCAAAGACATCCTCAAGGGCCTGTCGCTGGACATCCAGCCCGG
CCAGGTGCACGCCATCATGGGGCCCAACGGCGCCGGCAAATCGACCCTGGGCAATGTGCTCGCCGGTCGCGATGGCTACG
CAGTCACTGCCGGCAGCGTGCAGTTCGAAGGCGCCGACCTGCTCGACCTGCAGCCGGAAGAACGCGCTGCGGCCGGCCTG
TTCCTGGCCTTCCAGTACCCGGTGGAAATCCCCGGCGTAAACAACACCTACTTCCTGCGTGCCGCGCTCAATGCGCAGCG
CAAGGCGCGTGGCGAAGAAGAGCTGGATTCCATGCAGTTCCTCAAGCTGGTGCGGCAGAAGCTGGCGGTGCTGCATCTGA
AGGACGAGCTGCTGCACCGTGGCGTCAACGAAGGGTTCTCCGGCGGCGAAAAGAAGCGCAACGAGATCTTCCAGCTGGCC
GTACTCGAGCCGAAGTTGGCGATCCTGGACGAAACCGACTCCGGCCTGGATATCGATGCACTCAAGAGCGTGGCCGACGG
CGTCAATGCGCTGCGCTCGACCGAGCGTTCGTTCCTGGTGATCACCCATTACCAGCGCCTGCTCGACTACATCAAGCCGG
ACGTGGTGCATGTGCTGTCCGATGGGCGCATCGTGCAGAGTGGCGGCCCGGAGCTGGCGCTGGAGTTGGAAAAACACGGC
TACCACTTCCTGAAGGACCGTGTGGTGCCGGAGGCCGCCGCCTGA

Upstream 100 bases:

>100_bases
CCAAGTGCACCCAAACGGCACGATGCTTCGCACGAACCCTCACCCCAACCCCTCTCCCGGCAGGAGAGGGGCTACATACG
AATTCTGACGGACCATCAGC

Downstream 100 bases:

>100_bases
TGAGTGCCTTGTTGGAATCCCTTGCCAGCGGGTTTAGCGGCAATGCTGCACGGCGCGCCGAACTCGACGCGGCCTTGCAG
ACCGGCCTGCCCGGCCCGCG

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MLNIQNLHASIAGKDILKGLSLDIQPGQVHAIMGPNGAGKSTLGNVLAGRDGYAVTAGSVQFEGADLLDLQPEERAAAGL
FLAFQYPVEIPGVNNTYFLRAALNAQRKARGEEELDSMQFLKLVRQKLAVLHLKDELLHRGVNEGFSGGEKKRNEIFQLA
VLEPKLAILDETDSGLDIDALKSVADGVNALRSTERSFLVITHYQRLLDYIKPDVVHVLSDGRIVQSGGPELALELEKHG
YHFLKDRVVPEAAA

Sequences:

>Translated_254_residues
MLNIQNLHASIAGKDILKGLSLDIQPGQVHAIMGPNGAGKSTLGNVLAGRDGYAVTAGSVQFEGADLLDLQPEERAAAGL
FLAFQYPVEIPGVNNTYFLRAALNAQRKARGEEELDSMQFLKLVRQKLAVLHLKDELLHRGVNEGFSGGEKKRNEIFQLA
VLEPKLAILDETDSGLDIDALKSVADGVNALRSTERSFLVITHYQRLLDYIKPDVVHVLSDGRIVQSGGPELALELEKHG
YHFLKDRVVPEAAA
>Mature_254_residues
MLNIQNLHASIAGKDILKGLSLDIQPGQVHAIMGPNGAGKSTLGNVLAGRDGYAVTAGSVQFEGADLLDLQPEERAAAGL
FLAFQYPVEIPGVNNTYFLRAALNAQRKARGEEELDSMQFLKLVRQKLAVLHLKDELLHRGVNEGFSGGEKKRNEIFQLA
VLEPKLAILDETDSGLDIDALKSVADGVNALRSTERSFLVITHYQRLLDYIKPDVVHVLSDGRIVQSGGPELALELEKHG
YHFLKDRVVPEAAA

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9961252, Length=240, Percent_Identity=29.5833333333333, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI9961250, Length=240, Percent_Identity=29.5833333333333, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI4505771, Length=240, Percent_Identity=29.5833333333333, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI156105685, Length=240, Percent_Identity=27.5, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI42741659, Length=238, Percent_Identity=30.2521008403361, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI62526033, Length=234, Percent_Identity=28.6324786324786, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI27436953, Length=251, Percent_Identity=29.0836653386454, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI46592956, Length=219, Percent_Identity=30.5936073059361, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI46592964, Length=219, Percent_Identity=30.5936073059361, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI46592971, Length=219, Percent_Identity=30.5936073059361, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI46592915, Length=217, Percent_Identity=30.8755760368664, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI46592898, Length=217, Percent_Identity=30.8755760368664, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI46592978, Length=219, Percent_Identity=30.5936073059361, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787972, Length=247, Percent_Identity=63.1578947368421, Blast_Score=328, Evalue=2e-91,
Organism=Escherichia coli, GI1788761, Length=231, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787370, Length=242, Percent_Identity=25.6198347107438, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790467, Length=250, Percent_Identity=28.4, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87081709, Length=235, Percent_Identity=25.531914893617, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1789672, Length=236, Percent_Identity=25, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081791, Length=233, Percent_Identity=26.1802575107296, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787029, Length=239, Percent_Identity=23.8493723849372, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789891, Length=263, Percent_Identity=27.7566539923954, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790190, Length=231, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787500, Length=221, Percent_Identity=28.9592760180996, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787792, Length=231, Percent_Identity=25.974025974026, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI87082267, Length=207, Percent_Identity=28.9855072463768, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17558664, Length=233, Percent_Identity=31.3304721030043, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25146777, Length=245, Percent_Identity=27.7551020408163, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71996809, Length=231, Percent_Identity=28.1385281385281, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538654, Length=235, Percent_Identity=27.2340425531915, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193211017, Length=231, Percent_Identity=28.1385281385281, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193211015, Length=231, Percent_Identity=28.1385281385281, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324498, Length=233, Percent_Identity=26.1802575107296, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319856, Length=237, Percent_Identity=27.8481012658228, Blast_Score=65, Evalue=8e-12,
Organism=Drosophila melanogaster, GI85816269, Length=239, Percent_Identity=28.8702928870293, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24580553, Length=239, Percent_Identity=28.8702928870293, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI85724864, Length=239, Percent_Identity=28.8702928870293, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24580555, Length=239, Percent_Identity=28.8702928870293, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24641565, Length=220, Percent_Identity=29.5454545454545, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281363262, Length=233, Percent_Identity=31.3304721030043, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24653245, Length=233, Percent_Identity=31.3304721030043, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI17136592, Length=251, Percent_Identity=27.4900398406374, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27653; Mature: 27653

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNIQNLHASIAGKDILKGLSLDIQPGQVHAIMGPNGAGKSTLGNVLAGRDGYAVTAGSV
CCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCEEEECCE
QFEGADLLDLQPEERAAAGLFLAFQYPVEIPGVNNTYFLRAALNAQRKARGEEELDSMQF
EECCCCEECCCCHHHHHHEEEEEEECCEECCCCCCCEEEEEHHCHHHHHCCHHHHHHHHH
LKLVRQKLAVLHLKDELLHRGVNEGFSGGEKKRNEIFQLAVLEPKLAILDETDSGLDIDA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEEEEEEECCCEEEEECCCCCCCHHH
LKSVADGVNALRSTERSFLVITHYQRLLDYIKPDVVHVLSDGRIVQSGGPELALELEKHG
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCHHHEEHHCCCEEEECCCCEEEEEEHHCC
YHFLKDRVVPEAAA
CHHHHHCCCCCCCC
>Mature Secondary Structure
MLNIQNLHASIAGKDILKGLSLDIQPGQVHAIMGPNGAGKSTLGNVLAGRDGYAVTAGSV
CCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCEEEECCE
QFEGADLLDLQPEERAAAGLFLAFQYPVEIPGVNNTYFLRAALNAQRKARGEEELDSMQF
EECCCCEECCCCHHHHHHEEEEEEECCEECCCCCCCEEEEEHHCHHHHHCCHHHHHHHHH
LKLVRQKLAVLHLKDELLHRGVNEGFSGGEKKRNEIFQLAVLEPKLAILDETDSGLDIDA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEEEEEEECCCEEEEECCCCCCCHHH
LKSVADGVNALRSTERSFLVITHYQRLLDYIKPDVVHVLSDGRIVQSGGPELALELEKHG
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCHHHEEHHCCCEEEECCCCEEEEEEHHCC
YHFLKDRVVPEAAA
CHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]